• Applied Microscopy
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• v.40 no.1
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• pp.15-19
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• 2010

The present study was designed to demonstrate ionic zinc in the rat DRG by means of zinc selenium autometallography($ZnSe^{AMG}$). Ganglion cells varied in size from 15 to 100 ${\mu}m$. The smaller neurons were strongly stained with AMG, whereas the larger cells were weakly stained. Each large ganglion cell was surrounded by perineuronal satellite cells, showing apparent AMG staining. We demonstrated for the first time the existence of zinc-containing satellite cells in the rodent DRG. Using electron microscopy, fine AMG grains were observed scattered in the somata of the DRG neurons, especially small cells. However, much lower concentrations of the AMG grains occupied in the large cells, and these were mostly localized in lysosome-like organelles. These results indicate that zinc may be involved in sensory transmission in the DRG level.

• Journal of Oral Medicine and Pain
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• v.38 no.2
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• pp.109-114
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• 2013

Chemical burn on the oral mucosa is caused by contact with various chemical products and manifests with localized mucositis, keratotic white lesions, bleeding, and painful tissue surface due to the coagulation of the tissue. Policresulen ($Albothyl^{(R)}$) is a topical antiseptic, commonly used over-the-counter drug for vaginitis, thrush and stomatitis. This drug is highly acidic with pH 0.6, and can act as a strong corrosive agent to oral mucosa. When inadvertently used in oral cavity, it may cause chemical burns of oral mucosa, resulting necrosis and bleeding surface resembling to erythema multifome. A 56 years old female patient presented with the chief complaints of painful ulcerations on the tongue, the upper and lower lips. On intraoral examination, an erythromatous, erosive or ulcerative surface covered with inflammatory exudates or bleeding crust is observed on the anterior half of the tongue and the upper and lower lips. She has occasionally applied the policresulen solution topically on the tongue to relieve pain from recurrent focal glossitis for about 10 years. In this time she applied it broadly and repeatedly to the tongue, the upper and lower lips for the purpose of pain relief by herself without instruction by physician or dentist. After cessation of policresulen application, the oral mucosa was rapidly recovered with use of topical steroids. In 2 weeks the lesions subsided completely. In summary, inadvertent use of $Albothyl^{(R)}$ on oral mucosa may result in chemical burn, causing mucosal erosion, ulceration and inflammation. It can be recovered by topical use of corticosteroid for 2 weeks after cessation of using $Albothyl^{(R)}$.

• Journal of Oral Medicine and Pain
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• v.34 no.4
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• pp.429-433
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• 2009

Burning mouth syndrome (BMS) is defined as burning pain in the tongue or other oral mucous membrane associated with normal sign and laboratory findings at least 4 to 6 months. There are many factors that affect this condition and the pain characters are various among the sufferers, so it is difficult to diagnose exactly and treat properly. The cause of BMS is currently unknown. The etiology is presumed to be that it is related with local, systemic and psychogenic factor. The BMS is related with local factor such as allergic reaction, oral fungal infection(candidiasis), parafunctional oral habits and systemic factors such as diabetes mellitus, hypothyroidism, nutritional deficiencies(vitamin $B_{12}$, folic acid), hyposalivation and psychogenic factor such as depression, anxiety, cancerphobia. So clinicians must be aware of these factors and can give proper treatment options to patients. The management of BMS are pharmacologic management, cognitive behavioral therapy and psychotherapy treatment. Clonazepam, gabapentin, amitriptyline, alpha-lipoic acid and capsaicin are used to manage the BMS. Among these, topical clonazepam is reported that the effect is higher than systemic medication and the complications are rare. This case report is about some cases of the effect of topical clonazepam on BMS.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.7
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• pp.301-310
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• 2016

This is a nonequivalent control group non-synchronized experiment research to verify the effect of moxibustion therapy on efficient management of daily living disabilities and sleep patterns in elderly women with chronic low back pain. Total 12 sessions of moxibustion therapy were applied to elderly women(30 subjects in an experimental group and 30 subjects in a control group) in G City once a week for 12 weeks from March 15th to May $31^{st}$ 2015. Then the follow-up study was conducted 2 weeks after the post survey. For moxibustion, was applied to Shen-shu, Ashi point, Ta chang shu, Yang kuan and Yosu. 5 sheets of moxibustion were applied to 7 acupuncture points of Mugeukboyang moxibustion; Zu san li & Chu chi, Chung wan, Chung chi & Shui tao, Fei shu, Kao hung and Tien shu, Wijung respectively and experimental treatment was conducted. For assessing the degree of back pain, Visual Analog Scale(VAS) developed by Scott & Huskisson(1979) was used and for measuring the degree of daily living disability, Oswestry Disability Index, which was developed by Fairbank et al(1980) and translated and revised by Yim, Hyeon-sul et al.(1998), was used. For measuring sleep patterns, the sleep pattern measurement tool developed by Oh, Jin-su, Song, Mi-soon and Kim, Sin-mi(1998) was used. For data analysis, SPSS/WIN 18.0 was employed and Chi-square test, t-test and repeated measures ANOVA were performed. There were significant differences in pain score(F=2510.32, p<.001), daily living disability score(F=1937.82, p<.001) and sleep pattern score((F=15.54, p<.001) of elderly women that were provided with moxibustion therapy, compared to the control group. Therefore, it was found that moxibustion therapy made a positive contribution to reduction in pain and daily living disabilities and improvement in sleep quality. Based on this study finding, there is a need to apply moxibustion therapy to elderly people with chronic low back pain as a nursing intervention in future.

• Journal of Oral Medicine and Pain
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• v.14 no.1
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• pp.25-34
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• 1989

The author performed on epidemiological study of the TMD in 189 elderly people and 195 young people with Helkimo index. The clinical dysfunction index was based on data from clinical examination and the anamestic dysfunction index was based on data from the interview with the investigated person. The results were as follows : 1. In the elderly population, 27.5% reported that they had subjectively symptom of TMD but 43.4% had sign and symptoms of TMD in clinical examination. 2. The mean values for maximal opening differed significantly between elderly and young populations, 47.22mm and 51.44mm (p<0.001) and less than a 40mm opening was observed 7.9% in elderly population, 0.5% in young population (p<0.001). 3. The mean values for lateral movement to the right and left did not differ with age, which were 8.56mm and 8.47mm in elderly population, 8.90mm and 8.81mm in young population, but the mean value for protrusion differed significantly between elderly and young populations, 6.89mm and 7.64mm (p<0.01). 4. A higher incidence of TMJ noise was recorded in the elderly and young populations than young population, especially crepitus, but a higher incidence of clicking was recorded in young population (p<0.05).

• Journal of Oral Medicine and Pain
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• v.23 no.1
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• pp.57-64
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• 1998

Personality characteristics were studied by means of SCL-90-R test, Behavioral problem and pain site was studied Isleep disturbance, irregular eating habit, decreased physical activity, decreased social activity, increased emotional tension) by examination sheets. This study was conducted to examine the mature and extent of psychological difference between the students who failed the college-entrance examination and freshment and to determine whether psychological distress acts as a precipitate for craniocervical pain. 96students who failed the college-entrance examination (examination-failed student) and 86 freshmen were included in this study. The obtained results were as follows : Mean T-score of SCL-90-R primary scaled and global Indies in examination-failed students were significantly higher than the freshmen group. In comparison with examination-failed student group, the prevalence of neck and shoulder pain was significantly higher than the freshmen group. When the study and control group were compared in behavioral problem the study group had not more sound sleep than the control group. The study group had more irregular eating habit than control group. The study group had the lower physical activity than control group. The study group had poor social activity than control group. There was no significant difference in emotional tension.

• Journal of Oral Medicine and Pain
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• v.35 no.4
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• pp.237-243
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• 2010

Acanthosis nigricans usually has the characteristics that involve the development of darker pigmented patches and thickened skin with velvety texture on the body folds, and papillomatosis on lip and intraoral regions including tongue, gingiva, mucosa, palate. Malignant acanthosis nigricans, a type of acanthosis nigricans, occurs most commonly in association with underlying malignancy and characterically appears with three characteristic mucocutaneous lesion : especially of the lips and eyelids, hyperkeratosis of the palms and soles, the sign of Leser-Trelat. In the present report, the patient had typical clinical and histological findings of oral acanthosis nigricans, as well as past medical history associated with malignant gastric adenocarcinoma.

• Journal of Oral Medicine and Pain
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• v.15 no.1
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• pp.9-25
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• 1991

타액의 유동학적 성질은 타액의 윤활작용 및 구강내 경조직, 연조직 보호작용에 영향을 미친다. 그러므로 타액의 유동성을 잘 이해하면, 구강내 기능적 불편감의 평가와 인공타액의 개발에 필요한 중요한 정보를 얻을 수 있다. 저자는 전단율 변화에 따른 타액점도 변화의 연령 및 성별에 따른 차이를 알고자, 각 연령층별로 구강건조증으로 고통받은 병력이 없으며 타액채취시 약물을 복용하고 있지 않은 남녀 각 20명씩 총 240명을 대상으로 자극시 분비된 타액의 점도를 cone-and-plate 형태의 점도계를 이용하여 전단율 11.3에서부터 450.0(/sec )사이에서 측정하였다. 또, 20대 남녀 각각 20명의 경우, 자극시 분비 된 전타액의 점도와 함께 비자극시 분비된 전타액, 자극시 분비된 이하선 타액, 자극시 분비된 악하선 설하선 혼합타액의 점도를 같은 방법으로 측정한 결과 다음과 같은 결론을 얻었다. 1. 타액은 점탄성의 성질을 가지는 non-Newtonian 유체로서 점도와 전단율 사이의 관계는 점근선으로 표시될 수 있었다. 2. 자극시 분비된 전타액의 점도는 연령이 높을수록 증가된 양상을 보였으나, 남자의 경우 50대 이상에서 가장 높고 여자의 경우 30대에서 가장 높았다. 3. 자극시 분비된 전타액의 점도는 20대, 30대, 40대에서 여자가 남자보다 높았다. 4. 타액 점도는 자극시 분비된 악하선 설하선 혼합타액에서 가장 높았으며, 비자극시 분비된 전타액, 자극시 분비된 전타액, 자극시 분비된 이하선 타액 순이었다.

• Clinical and Experimental Pediatrics
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• v.52 no.9
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• pp.1038-1043
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• 2009

Two adolescent cases of Fitz-Hugh-Curtis syndrome, which has not been previously reported in Korean girls, presenting with right upper-quadrant abdominal pain, nausea, vomiting, and fever are reported here. A careful and thorough inquiry into the sexual history of the first patient, which was not done upon admission, led to a careful reassessment of the dynamic abdominal computed tomography scan revealing hepatic capsular enhancement without evidence of gallbladder or liver disease. Both cases were diagnosed noninvasively and were treated successfully by medical intervention. A high index of suspicion of Fitz-Hugh-Curtis syndrome should be implemented in the differential diagnosis of right upper quadrant pain, particularly in sexually active girls, for a prompt diagnosis and rapid cure.

• The Journal of Korean Orthopaedic Ultrasound Society
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• v.7 no.2
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• pp.132-137
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• 2014

We can test for small structures located at the surface layer as high resolution ultrasonic techniques and small probes were developed. Accordingly ultrasound became a useful tool in the diagnosis and treatment of wrist diseases. It is important to understand the anatomical structures and apply clinical features as well as these technical aspects when using ultrasound. The purpose of this article is to evaluate the usefulness and approach of ultrasound about typical diseases according to the area of the wrist pain.