• Clinical and Experimental Pediatrics
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• v.52 no.11
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• pp.1241-1248
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• 2009

Purpose:The etiology of Kawasaki disease (KD) is still unknown. Recently, an association between human coronavirus NL63 (HCoV-NL63) and KD was implicated. Hence, we attempted to determine the association between KD and acute respiratory viral infections. Methods:Nasopharyngeal aspirate samples were obtained from 54 patients diagnosed with KD at the Seoul National University (SNU) Children's Hospital and SNU-Bundang Hospital between October 2003 and September 2006. Viral diagnoses of 11 respiratory viruses were made using multiplex reverse transcriptase-polymerase chain reaction (RT-PCR): respiratory syncytial virus (RSV), adenovirus, rhinovirus (RV), parainfluenza viruses (PIVs) 1 and 3, influenza viruses (IFVs) A and B, human metapneumovirus (HMPV), human bocavirus (HBoV), HCoV OC43/229E, and HCoV-NL63. Clinical data were reviewed retrospectively. Results:The median age was 32 months (6 months-10.4 years). Respiratory symptoms were observed in 37 patients (69%). The following respiratory viruses were identified in 12 patients (22%): RV (n=4), PIV-3 (n=2), HBoV (n=2), and adenovirus, RSV, PIV-1, IFV-A, and HCoV-NL63 (n=1). Co-infection with PIV-3 and RV was observed in one patient. Respiratory symptoms were observed in 7 (58.3%) and 30 (71.4%) patients of the virus-positive and virus-negative groups (P>0.05). Response rate to intravenous immunoglobulin administration was 67% (n=8) and 86% (n=36) in the virus- positive and virus-negative groups (P>0.05). Conclusion:Respiratory symptoms were commonly observed in KD patients but the association between respiratory viruses and KD were not found. Large multicenter-based investigations are required to confirm the association between acute respiratory viral infections and KD.

• Pediatric Infection and Vaccine
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• v.29 no.2
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• pp.70-76
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• 2022

Coronavirus disease 2019 (COVID-19) in patients with underlying diseases, is associated with high infection and mortality rates, which may result in acute respiratory distress syndrome and death. Mucopolysaccharidosis (MPS) type II is a progressive metabolic disorder that stems from cellular accumulation of the glycosaminoglycans, heparan, and dermatan sulfate. Upper and lower airway obstruction and restrictive pulmonary diseases are common complaints of patients with MPS, and respiratory infections of bacterial or viral origin could result in fatal outcomes. We report a case of COVID-19 in a 16-year-old adolescent with MPS type II, who had been treated with idursulfase since 5 years of age. Prior to infection, the patient's clinical history included developmental delays, abdominal distension, snoring, and facial dysmorphism. His primary complaints at the time of admission included rhinorrhea, cough, and sputum without fever or increased oxygen demand. His heart rate, respiratory rate, and oxygen saturation were within the normal biological reference intervals, and chest radiography revealed no signs of pneumonia. Consequently, supportive therapy and quarantine were recommended. The patient experienced an uneventful course of COVID-19 despite underlying MPS type II, which may be the result of an unfavorable host cell environment and changes in expression patterns of proteins involved in interactions with viral proteins. Moreover, elevated serum heparan sulfate in patients with MPS may compete with cell surface heparan sulfate, which is essential for successful interaction between the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein and the host cell surface, thereby protecting against intracellular penetration by SARS-CoV-2.

• Journal of the korean academy of Pediatric Dentistry
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• v.48 no.3
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• pp.324-332
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• 2021

This study was conducted to investigate changes in dental visits in children and adolescents due to COVID-19. Based on the data provided by the Korea Health Insurance Review and Assessment Service, the number of dental visits among children and adolescents from January 2019 to August 2020, and the rate change according to Korean disease classification in 2019 and 2020 were analyzed by month and region. From January to August 2020, compared to the same period in 2019, the total number of visits to dental clinics and dental hospitals among children and adolescents decreased by 642,202 times (16.3%) in the 0 - 9 years old group, and 313,488 times (9.2%) in the 10 - 19 years old group. During the same period, the decreases due to Z29 (Need for other prophylactic measures) decreased by 118,219 times (34%) in the 0 - 9 years old group and 83,944 times (31%) in the 10 - 19 years old group, showing the greatest change. It is analyzed that overall dental service of children and adolescents has decreased due to COVID-19, and this may lead to deterioration of oral health of children and adolescents in the future, and this study can be used as a reference in case of an infectious disease such as COVID-19 in the future.

• Journal of the Korea Convergence Society
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• v.11 no.6
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• pp.423-431
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• 2020

This study attempted to identify the effects of stress caused by the COVID-19 epidemic on quality of life and the moderating effect of positive psychological capital. The study subjects were 180 adults, and data were collected from April 9 to April 15, 2020. For the collected data, frequency analysis, descriptive statistics, one-way ANOVA, Pearson's correlation coefficients, and hierarchical multiple regression analysis were used using SPSS WIN 23.0 program. As a result of the study, stress caused by the COVID-19 epidemic affected quality of life, and positive psychological capital showed a significant moderating effect. Based on this study, a study is needed to develop a program to mediate a lower quality of life due to stress caused by the COVID-19 epidemic and to verify its effectiveness.

• Journal of Korean Society of Archives and Records Management
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• v.20 no.4
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• pp.229-236
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• 2020

In light of SARS-CoV-2's significant impact, human society has experienced rapid changes in lifestyle that it has not yet experienced before. One way this virus has influenced people's lives is the emergence of the zero-contact society, an initiative for preventing the spread of infectious diseases. As can be seen, the social impact of COVID-19 is widespread. Various issues, such as those about government policy, personal information protection, and health care, are affecting society as a whole. At the same time, factual information is difficult to track and record because of the rapid and transient nature of related events and issues. As such, a method of effectively describing COVID-19 and real-time information is necessary. The "COVID-19: Our Memory" project is an attempt to record the sociocultural impact of the coronavirus infection. This project collects major events and issues classified into several subjects, records those events from a neutral point of view, and develops a digital archive so that all records are accessible. All the data collected and built through the project, the application, including the source code and visualization, are all published to bring about new opportunities for collaboration.

• Journal of Advanced Technology Convergence
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• v.2 no.3
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• pp.25-32
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• 2023

This study was conducted to find out the relationship between knowledge and attitudes about COVID-19 and infection control performance among college students in paramedicine. The subjects of the study were 154 university students attending a 3-4 year paramedicine located in Gwangju Metropolitan City, Jeollabuk-do Province, and the collected data were frequency, percentage, sum, average and It was analyzed by standard deviation, t-test, ANOVA(Scheffe), Pearson's Correlation Coefficient, and Multiple Linear Regression. The order of attitude and knowledge about COVID-19 affected the infection control performance of college students in the paramedicine. Therefore, it is necessary to develop and apply regular or non-regular curriculum and multidisciplinary curriculum that can improve knowledge and attitudes about COVID-19 in order to improve the infection control performance of paramedic students.

• Korean Journal of Occupational Health Nursing
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• v.29 no.3
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• pp.202-207
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• 2020

Purpose: COVID-19 infections have been erupting in places of worship, long-term care facilities, and call centers in Korea since January 2020. This study aims to diagnose and present an infection control system solution for long-term care facilities where at-risk elderly individuals are actively engaged in communal life. Methods: We conducted comparative analyses of infection control systems between long-term care facilities and medical institutions respective of relevant laws and this study's evaluation system. Results: To prepare for future infectious diseases, it is necessary to establish a long-term care facility infection control system and strengthen the standards thereof, to strengthen long-term care facility evaluation standards and to newly establish medical charges for infection control. Conclusion: Systematic procedure fortification and financial support provisions are necessary for infection control at long-term care facilities.

• Annual Conference on Human and Language Technology
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• 2021.10a
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• pp.85-90
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• 2021

코로나바이러스감염증-19로 인한 팬데믹 상황이 지속되면서 감염증 정보의 불확실성으로 인해 코로나 관련 루머가 온라인상에서 빠르게 전파되고 있다. 이러한 코로나 관련 가짜 뉴스를 사전에 탐지하기 위해, 본 연구에서는 한국어 코로나 가짜 뉴스 데이터셋을 구축하고, 개체명과 사용자 재확산 정보를 이용한 한국어 가짜 뉴스 탐지 모델을 제안한다. 가짜 뉴스 팩트체킹 언론인 서울대팩트체크센터에서 코로나 관련 루머 및 가짜 뉴스에 대한 검증 기사를 수집한 후, 기사로부터 개체명 추출 모델을 통해 주제 키워드를 추출하고, 이를 이용해 유튜브 상의 사용자 재확산 정보를 수집하여 데이터셋을 구성하였다. BERT 기반의 제안 모델을 다양한 비교군과 비교하였고, 특성 조합에 따른 실험을 통해 각 특성 정보(기사 텍스트, 개체명 데이터, 유튜브 데이터)가 가짜 뉴스 탐지 성능에 미치는 영향을 알아보았다.

• Journal of the Korean Society of Radiology
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• v.84 no.4
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• pp.964-969
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• 2023

Guillain-Barré syndrome (GBS) is an immune-mediated demyelinating polyneuropathy characterized by progressive, ascending, and symmetrical paralysis. It is known to be triggered by an antecedent infection or vaccination. Recently, GBS development following coronavirus disease 2019 (COVID-19) vaccination has been reported. Cranial neuropathies in typical GBS patients usually involve the facial and the lower cranial nerves (from IX to XII). We report a rare case of multiple cranial neuropathies involving trigeminal, abducens, and facial nerves in a patient who developed GBS following COVID-19 vaccination on the basis of obvious MRI features.

• Proceedings of the Korea Information Processing Society Conference
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• 2020.11a
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• pp.413-415
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• 2020

코로나 바이러스 감염증-19가 처음 발생한 이래로 확산세가 전혀 줄지 않고 계속 늘어나는 지금, 확진자는 물론이거니와 자가격리자에 대한 관리 또한 매우 중요하다. 국가 간 이동이나 코로나 바이러스 확진자와 접촉한 일이 있는 사람의 경우 2주간의 자가격리를 해야 되니만큼 그 숫자가 매우 많으며 그에 대한 관리 또한 중요하다. 이에 따라 본 논문에서는 블록체인을 이용하여 자가격리자에 대한 체계적이고 신뢰성 있는 관리 시스템을 제안한다. 프라이빗 블록체인 합의 알고리즘인 PBFT를 이용하여 방역당국과 같은 중앙에서 그것을 실시간으로 확인하여 자가격리 이탈자가 있을 경우 바로 알 수 있는 효과를 기대한다.