• Journal of Korean society of Dental Hygiene
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• v.13 no.3
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• pp.517-523
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• 2013

Objectives : The aim of the study is to investigate the antimicrobial activity of jaborandi and sorbitol to various oral microbes. Methods : Jaborandi leaves contain pilocarpine. The conditions for extraction were optimized on the basis of substances, temperatures and pHs. Total pilocarpine content after extraction was analyzed by HPLC. The herbal antimicrobial activity of jaborandi and sorbitol were evaluated for oral microbes containing ATCC 25175 S. mutans, ATCC 13419 S. salivarius, ATCC 6249 S. mitis, ATCC 33398 S. equi, ATCC 29213 S. aureus, ATCC 14053 C. albicans. Results : The optimum conditions for highest yielding extraction were pilocarpine content after boiling at $100^{\circ}C$ for 1 hour at pH 3. The level of total pilocarpine content was analyzed at 833 mg/kg by HPLC. The most effective antimicrobial activity was obtained by combination of pilocarpine and sorbitol rather than pilocarpine, menthol and sorbitol, respectively. Conclusions : This results supported the preventive oral health care using safe and convenient jaborandi herb.

• The Journal of Korean Academy of Prosthodontics
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• v.24 no.1
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• pp.91-103
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• 1986

Using imprint cultures and epithelial smears, the density and prevalence of colonization of oral mucosal sites and denture surfaces by Candida albicans has been determined in 28 healthy dentate subjects and 20 denture wearers. With questionnaire, oral and denture examination, the relationship between the carrier rates and several factors; DMFT, oral hygiene index, salivary pH & denture plaque score were studied. But these factors have not significant relationship to the carrier rates. Imprint culture appears to be sensitive technique for detecting candidal carriers and be useful for distinguishing between the healthy carrier state and candidal infection. Cigarette smokers had a significantly increased carrier state (P<0.05) compared with nonsmoker in male dentate subjects. Female were more frequent carriers than male in dentate and denture group, but these differences were not significant. In denture wearers, there was a higher density and frequency of candidal colonization of all mucosal sites sampled, compared with that of healthy dentate group especially anterior palate and posterior palate showed highly significant differences in frequency of candidal colonization (P<0.05). The distribution of Candida albicans is not uniform throughout the mouth. The tongue in the healthy dentate subjects and the impression surfaces of upper dentures are the primary oral reservoirs for the fungus. Overnight wearing of dentures was associated with increased density and frequency of candidal colonization and density.

• Journal of Dairy Science and Biotechnology
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• v.37 no.1
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• pp.49-56
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• 2019

Vulvovaginal candidiasis is a major urogenital infection in women. Lactobacilli are important in maintaining vaginal health. In the present study, the effect of heat adaptation at $47{\sim}52^{\circ}C$ prior to heat stress at $60^{\circ}C$ in improving the viability of Lactobacillus salivarius MG242 was examined. L. salivarius MG242 has antifungal effects against Candida albicans. Heat-adapted cells had a higher survival rate than non-adapted cells during the subsequent heat stress. When chloramphenicol was added during the adaptation process, heat tolerance was abolished, suggesting the involvement of de novo protein synthesis with the heat adaptation of L. salivarius MG242 strain. Exopolysaccharide quantification and scanning election microscopy did not reveal any appreciable changes during heat adaptation. The antifungal activity of L. salivarius MG242 against C. albicans was maintained during the heat adaptation. These results suggest that heat adaptation can be applied for the development of probiotic products using L. salivarius MG242 to improve its stress tolerance during processing.

• Archives of design research
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• v.17 no.2
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• pp.373-382
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• 2004

The value of Korean ginseng has been known in the world since the 4th century B. C. Red ginseng is hot-steamed, and then dried for the purpose of long-term storing. Through the steaming and drying process, its moisture rate is reduced to 14% and its color becomes citrine or light yellowish brown. Its hardened structure enables long-term storage without any deformation. Especially, Korean red ginseng contains substances that promote micro-physiological activities which are not found in American or Sanchi ginseng. Ginseng is produced in diverse forms for the customer's convenience. In this study, these are classified as sliced, dried, and honeyed ginseng, granulated tea, extract, powder, capsules, tablets, drinks and candy. Package design is one of the most effective method in the marketing fields. However, in this research, we found that red ginseng packages are not variously and properly developed in materials and designs. The research pointed out the problems and discuss ways and means of the package design.

• Journal of Fashion Business
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• v.7 no.2
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• pp.15-25
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• 2003

In this study on the Persiandress called Persiandress or Mediandress, its names, styles, and structures that are still subject to a great deal of controversy were investigated. In addition, the reason why the Persiandress was wrongly named as Kandys by the early researchers was also examined. The documents of reliefs on the Apadanastairs in Persepolis and the European papers concerning this themes were subject of this analysis. Such investigation and examination results are summarized as follows. There is still no agreed name describing the Persiandress, which is called "Persiandress" or "Mediandress". Further, there is no definite conclusion on whether the Persiandress was made in one piece or two pieces. The first person who insisted that the Persiandress was made in one piece is a German archaeologist, Ernst Herzfeld. He said that the Persiandress was made in one long tetragonal piece, had a hole in the middle for head, and had lots of pleats when it was tied with a belt. On the contrary, researchers who insisted that the Persiandress was made in two pieces stressed the sleeve pleats in four folds, which is one of the representative characteristics, and said that such four-fold sleeve pleats would not be formed when the Persiandress was made in one piece and worn by a belt. Consequently, they have conducted studies according to their insistence and the resultant pattern. Kandys, the Median's typical dress, is a coat worn over the jacket and trousers. Although it had sleeves, the Median did not use them. Indeed, Kandys was used as a kind of cloak. However, the wrong term, Kandys is still used in Korea. So, it is necessary to correct use of such wrong term.

• Korean Journal of Food Science and Technology
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• v.18 no.5
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• pp.389-392
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• 1986

To evaluate a pigment of the flower of cockscomb, Cclosia critata. as a natural food colorant, jelly-po, candy and sherbet were chosen as model foods and colorized to red with the pigment of the flower. Color changes were evaluated by analyses with Hunter color difference colorimeter. Lovibond tintometer and UV-visible spectrophotometer. Also sensory evaluation was carried out. The results obtained indicated that the red pigment of the flower had a good potential as food colorant, when it is utilized under the certain limited conditions: low water activity such as candy or low temperature. Data obtained indicated good correlation between instrumental analyses and sensory evaluation as well.

• Proceedings of the Korean Society of Dyers and Finishers Conference
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• 2012.03a
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• pp.69-69
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• 2012

지구상에는 약 40만 종의 식물이 존재하는 것으로 알려져 있으며 이 중에 는 질병의 치료를 위한 약재로 이용되거나 나무는 대부분 목재 등으로 이용된다. 향나무(Juniperus chinenesis L.)는 항균성 및 방충성이 뛰어난 상록수로서 목재는 조각재나 가구재로 사용되고 민간 및 한의학에서 다양한 증상의 약재로 쓰이고 있으며 부패한 냄새를 제거할 목적이나 향재 및 향료로도 쓰이고 있다. 열매의 정유성분은 화장품, 술, 캔디 등에 사용되며 cedrol은 향료보류제, 유분은 훈향료, 목부는 고혈압, 곽란, 심복통, 통기파혈에 쓰인다. 향나무는 폴레페놀 성분이 함유되어 있고 피톤치드가 많이 나오는 것으로 알려져 있으며 심재의 폴리페놀 화합물은 항암, 항균, 항알러지, 노화방지 및 심장질환 등을 예방하거나 지연시키는 등 광범위한 약리학적 활성을 나타내어 식품, 의약품, 화장품, 향료등 다양한 분야에 활용되고 있다. 향나무 추출물에 관한 연구로는 성분분석과 생리활성 등에 관한 의약학 분야의 다양한 연구와 항산화, 항균활성 등 약리작용에 연구가 최근 다양하게 이루어지고 있는 것을 볼 수 있다. 측백나무속에 속하는 나무들은 대부분 정유 성분을 함유하고 있는 특성으로 항균성 등 바이오 기능성 소재 개발을 위한 연구가 활발히 진행되고 있으나, 향나무 추출물의 염색성에 관한 연구는 찾아보기 어려운 실정이다. 이에 본 연구에서는 다양한 용매를 이용하여 향나무의 잎, 열매, 수피, 심재 각 부위 추출물을 이용하여 견직물에 대한 염색성을 살펴봄으로써 향나무 추출물을 활용한 천연염색과 염재로서의 가능성을 확인하고자 하였다. 실험 결과 증류수를 염액 용매로 염색한 결과 모든 추출물의 잎, 열매 염색포의 색상은 대부분 옅은 Y계열로 나타났으며 향나무의 수피와 심재 염색포는 대부분 적색기미가 강한 YR계열로 나타났다. 에탄올 혼합액을 염액 용매로 하여 염색한 결과 향나무의 잎과 열매의 색상은 대부분 Y계열의 색상을 나타냈고 유기용매 추출염색포에서 정유성분으로 추정되는 물질 때문에 균염이 어려웠으며 수피와 심재 염색포에서 대부분 R계열의 색상이 뚜렷이 나타났다.

• Microbiology and Biotechnology Letters
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• v.37 no.3
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• pp.273-279
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• 2009

Hyungbangjihwang-Tang (HT), an Oriental herbal formula, has been known to play a role which helps to recover vigor of human in the Orient. In this study, antifungal substance (HTI) was purified from the ethyl-acetate extracts of HT by using $SiO_2$ column chromatography and HPLC, and the antifungal effects of HTI and its mode of action were investigated. By using a broth micro-dilution assay, the activity of HTI was evaluated against fungi. HTI showed antifungal activities without hemolytic effect against human erythrocytes. To confirm antifungal activity of HTI, we examined the accumulation of intracellular trehalose as stress response on toxic agents and effect on dimorphic transition in Candida albicans. The results demonstrated that HTI induced the accumulation of intracellular trehalose and exerted its antifungal effect by disrupting the mycelial forms. To understand its antifungal mode of action, cell cycle analysis was performed with C. albicans, and the results showed HTI arrested the cell cycle at the S phase in yeast. The present study indicates that HTI has considerable antifungal activity, deserving further investigation for clinical applications.

• Journal of Korean Society of Rural Planning
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• v.19 no.4
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• pp.261-268
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• 2013

사무르디는 스리랑카의 빈곤퇴치를 위한 프로그램 중 가장 규모가 큰 사회복지 지원 사업으로 1995년 청년, 여성, 장애인 등의 취업기회의 제공과 역량을 제고하여 궁극적으로 국가의 빈곤을 퇴치하고자 중앙정부에 의해 마련되었다. 본 연구는 사무르디 프로그램 수혜자의 만족도를 높이기 위한 사회경제적 관련 인자들이 무엇인지를 밝히고자 하였다. 사례연구지역은 스리랑카 중부지역에 위치한 오지이며 빈곤도가 높아 본 프로그램의 수혜율이 비교적 높은 캔디(Kandy) 지역을 대상으로 하였다. 본 프로그램의 주목적인 소득향상을 비롯하여 훈련프로그램, 사무르디은행의 신용, 정부보조금, 보험금, 기술정보제공, 마케팅시설, 고용기회제공, 도로개발, 관개수로시설 및 공공기반시설 등 프로그램의 지원내용 등과 관련된 다양한 인자들을 대상으로 수혜자의 만족도는 물론 이에 영향을 미치는 사회경제적 인자의 특성 등을 밝히고자 하였다. 다단계 표본 추출방법으로 150 사무르디프로그램 수혜자를 선정하여 관련 설문조사를 실시하였으며(유효설문 127), SAS9.1 통계분석용 소프트웨어를 사용하여 빈도분석, 회귀분석 등을 실시하였다. 그 결과 사무르디 수혜자들은 정부보조 및 사무르디 은행의 신용 제공, 보험금 지급, 도로개발, 소득 증대 등에 대해서는 만족도가 매우 높은 반면 종자나 비료 등의 농업투입요소나 마케팅시설, 기술정보 제공 등에 대해서는 비교적 낮은 만족도를 보였다. 회귀분석 결과 사무르디 프로그램 실시 후 소득증대, 고용 기회와 훈련프로그램 제공, 사무르디 은행의 신용 제공 등이 중요한 요인임을 확인할 수 있었다. 본 사무르디 프로그램을 통하여 지역주민의 생활여건 개선은 물론 소득을 향상시켜 나아가 빈곤 퇴치라는 본래의 취지와 역할을 제대로 수행하기 위해서는 농업인 조직 강화, 농산물집하시설 등 마케팅 및 유통 시설 확충, 농기계 지원, 농업생산시설 등을 지속적으로 확충하여야 할 것이며, 정부의 지속적인 모니터링과 평가 등을 통하여 사무르디 프로그램을 보다 긍정적으로 발전시켜 나가야 할 것이다.

• Journal of the Korean Dietetic Association
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• v.26 no.1
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• pp.30-41
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• 2020

As the morbidity of chronic diseases such as diabetes and high blood pressure has increased, the frequency of oral dryness upon taking drugs for a long time or several drugs at the same time has greatly increased. This study was conducted to investigate the status of oral dryness and utilize the data to develop treatment products. Surveys were assembled from October to December 2018, and a statistical analysis of the 144 responses was conducted. The surveyed consisted of 60 males and 84 females, with 31.3% of those in their 70s and older. Among them, 100 people took drugs for chronic diseases, while 27 people took drugs for more than 10 years and less than 20 years. Exactly 23 respondents who took drugs suffered from more than two types of chronic diseases, of which high blood pressure was the most cited, followed by hyperlipidemia and diabetes. Regarding complications, oral dryness (33.8%) was the most frequent, and there were significant differences in the degree of discomfort when taking medicine, especially for oral dryness depending on the age (P<0.05). Groups that took medicine showed severe symptoms of dry mouth, especially when waking up at night or in the morning (P<0.001) and eating food (P<0.01), and had difficulty in swallowing food (P<0.01) and speaking (P<0.01). Exactly 89.6% of the respondents didn't take lozenges (candy) for improvement of oral dryness, and the type of the product that they wanted to purchase the most was candy (45.1%). Respondents worried about rising blood sugar, dental caries, and calories when eating candy for relieving dryness (P<0.01).