• Journal of Science Education
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• v.43 no.3
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• pp.342-362
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• 2019

This study is to explore the applicability of PBL classes in undergraduate education at a School of Dentistry. To do this study, PBL modules were developed and applied to the students with different background knowledge to easily learn Integrated Medicine and Lifescience classes. Participants were 12 students in the first year of Integrated MS program at P University. Four tutors who majored in Dentistry and had PBL teaching experience participated. As a result of the PBL classes, students' concepts and knowledge about gene expression and expression were expanded, and they recognized the importance of self-directed learners and experienced the importance of collaborative learning. PBL tutor presented a positive assessment of attending PBL class experience and the educational need for PBL instruction. The results of this study show the possibility of PBL as a model for Integrated Medicine and Lifescience class in Dentistry education.

• The Korean Journal of Oral and Maxillofacial Pathology
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• v.42 no.6
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• pp.167-174
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• 2018

Natural products are vastly utilized as a source of chemotherapeutic agents for human cancers. Kochia scopraia is traditionally used for the cure of urological and dermatological diseases. Recently, methanol extract of Kochia scoparia (MEKS) has been shown to have anti-cancer activity to various human cancers. However, there is no report demonstrating the anti-cancer activity of MEKS in human mucoepidermoid carcinoma (MEC) cells. In this study, the authors studied the effects of MEKS on the cell proliferation and underlying mechanism in YD15 human MEC cells. MEKS decreased YD15 cell proliferation proven by trypan blue exclusion assay and induced apoptosis, evidenced by cell cycle analysis and western blotting. Autophagy induction by MEKS was verified by western blotting. In addition, MEKS regulated the expression of phosphorylated Akt, phosphorylated p38 and Nrf2 protein. This results can imply that MEKS might be a potential candidate for the treatment of human MEC cells.

• Journal of Dental Rehabilitation and Applied Science
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• v.40 no.3
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• pp.107-113
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• 2024

Temporomandibular disorder is a disease caused by various factors such as trauma, mental stress, occlusal factors, and parafunctional habits. Among them, many scholars have been interested in the relationship between occlusion and temporomandibular disorder for a long time and have conducted numerous studies, but controversy over this relationship continues to this day. Based on previous studies, this review clearly establishes the relationship on occlusion and temporomandibular disorders and presents the direction for follow-up research by summarizing the limitations of current studies.

• Journal of the Korean earth science society
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• v.27 no.4
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• pp.486-502
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• 2006

Earth Science is the study of Earth, where diverse organisms live, and it mainly focuses on the healthy, wealthy, and comfortable environment for our descendants. UNESCO and IUGS recently established the International Working Group on Medical Geology (1996), IGCP 454 Medical Geology (2000-2004), and International Medical Geology Association (IMGA, 2006) with the primary concerns of increasing awareness of Medical Geology among scientists, medical specialists, and the general public. Medical Geology and IMGA have been very successful in informing(educating) about the relationship between geological factors and health problems in humans and animals in the world through numerous international meetings, seminars, workshops, symposiums, and publications. Since there is a close correlation between Earth Science and Medical/ Dental Sciences as shown in the Medical Geology and IMGA, Earth Science, as with other areas in science, (i.e., Biology, Chemistry and Physics) should be included in the Medical Education Eligibility Test (MEET) and Dental Education Eligibility Test (DEET) for the Medical and Dental Graduate School. In this brief note, services and activities of UNESCO IGCP 454 Medical Geology and IMGA are introduced, sothat the inclusion of Earth Science as a subject requirement in the MEET and DEET can be considered. Such outcome will balance the development of Science Education in Korea.

• The Journal of Korean Academy of Prosthodontics
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• v.59 no.4
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• pp.405-414
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• 2021

Purpose. This study was conducted to evaluate clinical usefulness by evaluating the marginal bone resorption and survival rate of an implant with a taper straight type SLA surface domestically available on the market recently. Materials and methods. 40 implants satisfying the including criteria were observed for one year of 125 implants of 83 adult men and women who had KISPLANT^® implanted from August 2016 to December 2019 at the Department of Periodontology, Chonnam National University Dental Hospital. The marginal bone level was measured on periapical radiographs taken initially and 1 year later and we analyzed implant survival and success rates. A t-test was used for the analysis of the association between the marginal bone resorption and the severity of periodontitis, supportive periodontal therapy, the inserted site, the cause of extraction, immediate placement, and systemic disease. Results. After 1 year of loading, the mesial bone resorption was 0.74 ± 1.07 mm, and the distal bone resorption was 0.53 ± 1.04 mm. The marginal bone resorption of 2 mm or more occurred at 3 implants out of 40 implants after 1 year, so the success rate of implant was 92.5% and survival rate was 100%. There was a significant difference in mesial marginal bone resorption according to the inserted site and no significant differences were found between marginal bone resorption and the other factors. Conclusion. As a result of marginal bone resorption, success rate, and survival rate in this study, we found little marginal bone resorption and high survival and success rate. It can be concluded that they represent excellent clinical results.

• Journal of the korean academy of Pediatric Dentistry
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• v.50 no.3
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• pp.318-333
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• 2023

The purpose of this study is to analyze changes in dental trauma in children under the age of 12 during the period of Coronavirus Disease 2019 (COVID-19). March 2020, when COVID-19 was officially declared a pandemic by the World Health Organization, was set as the starting point for COVID-19. From March 2018 to February 2020, subjects in the pre-COVID-19 period were classified as the Pre-COVID-19 group, and from March 2020 to March 2022, subjects in the post-COVID-19 period were classified as the COVID-19 group. Information related to trauma was collected through electronic medical records. The number of trauma patients before and after the outbreak of COVID-19 decreased significantly. During the COVID-19 period, there was no significant difference in the male-female ratio or the distribution order of age groups. In the COVID-19 group of permanent teeth, the ratio of trauma caused by personal mobility was higher than trauma caused by sports. In the COVID-19 group of permanent teeth, the ratio of crown fracture with pulp involvement was significantly higher than the ratio of crown fracture without pulp involvement. Changes in trauma patterns caused by COVID-19 were observed more clearly in school-aged children than in preschool children. In a pandemic situation such as COVID-19, it is expected to be used as a good educational basis for knowing that frequent diagnoses can change due to changes in the environment.

• Korean Journal of Dental Materials
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• v.45 no.4
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• pp.301-310
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• 2018

The purpose of this study is to evaluate the compatibility of universal adhesives with two dual-cured resin cements. Eighty human molars were divided into eight groups. Tooth was embedded in self-curing acrylic resin and sectioned horizontally to exposure dentine surface. After polishing with 600-grit SiC paper, adhesives were applied. All-Bond Universal (Bisco), G-premio bond (GC), Scotch-bond universal (3M ESPE), Scotch-bond Multipurpose (3M ESPE) were used in this study. Calibra (Dentsply) as a conventional dual-curing resin cement and RelyX Ultimate (3M ESPE) as an amine free resin cement were used. The adhesives and the cements were applied according to the manufacturer's instructions. Final specimens were cylinder (diameter 2mm, height 3mm) shape. After storing in distilled water at $37^{\circ}C$ for 7 days the shear bond strength (SBS) test was performed. There was no significant difference in shear bond strength between the adhesives when RelyX Ultimate was used (p>0.05). However, when Calibra used with Scotch-bond Multipurpose and All-Bond Universal were used, statistically higher SBS was observed, as compared to the groups which Calibra cements with G-premio bond and Scotch-bond universal adhesive (p<0.05) were used. Within the limitations of this study, RelyX Ultimate resin cement was compatible with universal adhesives of various pH. All-Bond Universal adhesive was compatible with a resin cement containing the tertiary amine.

• Journal of the korean academy of Pediatric Dentistry
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• v.48 no.3
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• pp.280-290
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• 2021

Color stability of pulp-capping material is considered vital to the final aesthetic result since the material is placed in the coronal area. The purpose of this study was to compare the color stability of various pulp-capping materials by analyzing color change of tooth over time. A cavity was formed in the crown of the extracted premolar, and 4 types of pulp-capping materials were filled. Color assessment was performed with a spectrophotometer at different intervals: before placement; immediately after material placement; 1 day, 1 week, 2 weeks, 4 weeks, 8 weeks, 12 weeks, and 16 weeks after placement. Proroot white MTA^® and TheraCal LC^® showed a significant decrease in the L^* value and an increase in the ∆E^* value over time. In contrast, Biodentine^® and Well-Root^TM PT showed no significant change in the L^* value and maintained a steady ∆E^* value. The application of pulp-capping materials containing bismuth oxide as a radiopacifier may result in a color change of teeth. Long-term color stability of pulp-capping materials should be considered when treating teeth with thin enamel thickness or in aesthetically important area.

• Journal of the korean academy of Pediatric Dentistry
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• v.49 no.3
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• pp.274-284
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• 2022

The purpose of this study was to analyze the trend of the number of births in Gwangju and the number of outpatients in Pediatric Dentistry at Chonnam National University Dental Hospital over the past 10 years (2010 - 2019) and predict the next year using time series analysis. The number of births showed an unstable downward trend with monthly variations, with the highest in January and the lowest in December. The average number of births in 2020 was predicted to be 682 (595 to 782, 95% CI), and the actual number of births was an average of 610. The number of outpatients was relatively stable, showing a month-to-month variation, with highest in August and the lowest in June. The average number of patients in 2020 was predicted to be 603 (505 to 701, 95% CI), and the average number of actual visits was 587. Despite the decrease in the number of births, the number of outpatients was expected to increase somewhat. Due to the special situation of COVID-19, the actual number of births and patients was to be slightly lower than the predicted values, but it was that they were within the predicted confidence interval. Time series analysis can be used as a basic tool to prepare for the low fertility era in the field of pediatric dentistry.

• Journal of the korean academy of Pediatric Dentistry
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• v.50 no.3
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• pp.263-276
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• 2023

The purpose of this study was to evaluate the performance of a model using You Only Look Once (YOLO) for object detection of proximal caries in periapical radiographs of children. A total of 2016 periapical radiographs in primary dentition were selected from the M6 database as a learning material group, of which 1143 were labeled as proximal caries by an experienced dentist using an annotation tool. After converting the annotations into a training dataset, YOLO was trained on the dataset using a single convolutional neural network (CNN) model. Accuracy, recall, specificity, precision, negative predictive value (NPV), F1-score, Precision-Recall curve, and AP (area under curve) were calculated for evaluation of the object detection model's performance in the 187 test datasets. The results showed that the CNN-based object detection model performed well in detecting proximal caries, with a diagnostic accuracy of 0.95, a recall of 0.94, a specificity of 0.97, a precision of 0.82, a NPV of 0.96, and an F1-score of 0.81. The AP was 0.83. This model could be a valuable tool for dentists in detecting carious lesions in periapical radiographs.