• Title/Summary/Keyword: 치수합성

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Histological evaluation of direct pulp capping with DSP-derived synthetic peptide in beagle dog (비글견에서 DSP 유도 합성 펩타이드를 이용한 직접 치수 복조술에 대한 조직학적 연구)

  • Kim, Jae-Hoon;Hong, Jun-Bae;Lim, Bum-Soon;Cho, Byeong-Hoon
    • Restorative Dentistry and Endodontics
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    • v.34 no.2
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    • pp.120-129
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    • 2009
  • The purpose of this study was to investigate the pulpal response to direct pulp capping with dentin sialoprotein (DSP) -derived synthetic peptide in teeth of dogs, and to compare its efficacy to capping substances $Ca(OH)_2$ and white mineral trioxide aggregate (WMTA). A total of 72 teeth of 6 healthy male beagle dogs were used. The mechanically exposed pulps were capped with one of the following: (1) DSP-derived synthetic peptide (PEP group): (2) $Ca(OH)_2$ (CH group): (3) a mixture paste of peptide and $Ca(OH)_2$ (PEP+CH group): or (4) white MTA (WMTA group). The access cavity was restored with a reinforced glass ionomer cement. Two dogs were sacrificed at each pre-determined intervals (2 weeks, 1 month, and 3 months). After the specimens were prepared for standard histological processing, sections were stained with hematoxylin and eosin. Under a light microscope, inflammatory response and hard tissue formation were evaluated in a blind manner by 2 observers. In the PEP group, only 3 of 17 specimens showed hard tissue formation, indication that the DSP-derived synthetic peptide did not induce proper healing of the pulp. Compared with the CH group, the PEP group demonstrated an increased inflammatory response and poor hard tissue formation. The CH and WMTA groups showed similar results for direct pulp capping in mechanically exposed teeth of dogs.

THE CYTOTOXICITY OF PULPOTOMY MEDICAMENTS ON HUMAN PULP FIBROBLAST CELLS (치수 절단술 약제의 치수 섬유모세포에 대한 세포독성 연구)

  • Lee, Yeong-Hee;Lee, Keung-Ho
    • Journal of the korean academy of Pediatric Dentistry
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    • v.27 no.1
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    • pp.151-160
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    • 2000
  • The effect of concentration as factor in cytotoxicity, protein synthesis and alkaline phosphatase activity was compared for pulpotomy medicaments (formaldehyde, formocresol, paraformaldehyde, ferric sulfate) Human pulp fibroblasts were exposed to a range of concentrations(0.01, 0.05, 0.10, 0.25, 0.50, $1.00{\mu}l/ml$) of each agents, for period of 24hrs. The cell activities were evaluated by MTT assay, protein assay and alkaline phosphatase activity examination. The results as follows : 1. After 24hrs culture, pulp fibroblasts adding formaldehyde, formocresol and paraformaldehyde were suppressed cell activities with concentration increasing, but, no depression of cell activities by ferric sulfate. No significant difference was in formaldehyde, formocresol and paraformaldehyde. 2. Protein synthesis by pulpotomy agents were not significant difference in pulp fibroblasts but protein synthesis were a little decreased by paraformaldehyde. 3. Alkaline phosphatase activity was a little decreased by pulpotomy medicaments.

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THE COMPARISON OF GENE EXPRESSION FROM HUMAN DENTAL PULP CELLS AND PERIODONTAL LIGAMENT CELLS (사람 치수 세포와 치주 인대 세포의 유전자 발현에 관한 비교 연구)

  • Hyoun, So;Park, Sang-Hyuk;Choi, Gi-Woon
    • Restorative Dentistry and Endodontics
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    • v.34 no.5
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    • pp.430-441
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    • 2009
  • The purpose of this study was to characterize functional distinction between human dental pulp cells(PC) and periodontal ligament cells(PDLC) using cDNA micro array assay and to confirm the results of the microarray assay using RT-PCR. 3 genes out of 51 genes which were found to be more expressed(>2 fold) in PC were selected, and 3 genes out of 19 genes which were found to be more expressed(>2 fold) in PDLC were selected for RT-PCR as well. According to this study, the results were as follows: 1. From the micro array assay, 51 genes were more expressed (2 fold) from PC than PDLC. 2. RT-PCR confirmed that ITGA4 and TGF ${\beta}2$ were more expressed in PC than in PDLC 3. From the micro array assay, 19 genes were more expressed (2 fold) from PDLC than PC. 4. RT-PCR confirmed that LUM, WISP1. and MMP1 were more expressed in PDLC than in PC. From the present study, different expression of the genes between the PC and PDLC were characterized to show the genes which play an important role in dentinogenesis were more expressed from PC than PDLC, while the genes which were related with collagen synthesis were more expressed from PDLC than PC.

A Study of Mechanism Synthesis of One-Degree-of-Freedom Planar Linkages with Revolute Joints (회전대우를 갖는 1자유도 평면기구의 기구합성에 관한 연구)

  • 조선휘;신동원
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.17 no.6
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    • pp.1330-1341
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    • 1993
  • The kinematic synthesis deals with the systematic design of mechanisms for a given performance. The area of synthesis may be grouped into two categories to determine the type and to size the dimensions of a mechanism for a specified task. In this paper, using a database of mechanisms a designer can determine the type of mechanism conveniently and design equations are automatically generated for a given input performance. The solving method of design equations utilizes an optimization routine to obtain roots effectively. The linkages of 4, 6, and 8bars with revolute joints are considered in this study but may be extended to linkages of more bars.

한국인 운전자의 성별, 체형, 신체 치수를 고려한 내수용 승용차 규격 개선에관한 연구

  • 신원경;박민용
    • Proceedings of the ESK Conference
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    • 1998.04a
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    • pp.25-30
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    • 1998
  • 본 연구는 점점 다양해지고있는 사용자들의 성별, 체형, 신체치수를 고려한 내수용 승용차 규격 개선 을 위한 기초연구로서 기존의 승용차 연구에서 특별히 고려되지 않은 여성 운전자를 대상으로 기초 연 구를 한 후 여러 운전자 체형에 맞는 승용차 규격을 제안하고자 한다. 본 논문에서는 우선 여성 운전자 들이 부적합한 자동차 규격으로 느끼는 여러 불편 사항을 설문조사를 통해 조사하여 규격 개선의 방향 을 분석한 후, 한국인 인체 치수자료를 이용하여 각 퍼센타일을 통합한 여성 운전자를 3차원 인체 모델 링 도구를 이용하여 모델링 한 후 주요 내수용 승용차의 실제규격과의 비교를 통한 비적합성 여부를 파 악한다. 그 결과에 의하여 한국인 운전자의 성별과 체형을 다양하게 고려한 내수용 승용차의 규격 개선 을 제안하고자 한다.

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Edutainment를 결합한 스토리텔링의 하천개발 적용

  • Park, Ki-Bum;Park, So-Yoon;Kim, Sung-Won
    • Proceedings of the Korea Water Resources Association Conference
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    • 2012.05a
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    • pp.751-754
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    • 2012
  • 에듀테인먼트는 교육(education)과 오락(entertainment)의 합성어이다. 교육적인 내용을 놀이와 접목시킨 것을 말한다. 최근 하천개발은 치수적인 면에 개발과정을 넘어서 친수적인 면, 환경적인 면을 부각시켜 보다 질높은 삶을 살아가는 방향으로 발전하고 있다. 치수사업에 있어서도 과거의 제방중심의 사업에서 보다 다양하고 진보된 대책의 개발과 적용이 이루어지고 있다. 이러한 치수적인 안정을 기반으로 친수적인 면이 부각되면서 보다 접근성이 용이하고, 친수적인 하천의 개발이 지속적으로 이루어지고 있다. 최근의 지역축제로 성공적인 하천 축제로 강원도 양양군 연어축제(남대천), 경상북도 봉화은어축제(내성천)등이 있다. 이러한 축제들은 주요내용이 물고기를 잡는 체험과 관계기관의 적극적인 참여와 관리로 전국의 관광객들이 찾는 축제로 발전하고 있다. 일반적으로 이러한 축제들은 대상어종에 대해 설명하고 있으며, 물고기를 잡는 체험으로 진행되고 하천에 대한 스토리를 접목시키지만, 하천변 개발로 이루어지는 것은 부족한 실정이다. 본 연구에서는 하천개발에 있어 다양한 소재를 접목시켜 친수적 하천개발에 교육적 요소를 결합하여 스토리 텔링기법으로 하천을 개발하는 방안을 제안하였다.

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30대 여성의복의 치수적 합성을 위한 연구

  • 홍수숙;류경옥;서미아
    • Proceedings of the Costume Culture Conference
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    • 2003.09a
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    • pp.95-96
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    • 2003
  • 오늘날 여성은 고학력화와 더불어 여성 전문직 비율 증가, 직장에서의 승진기회 확대, 소득증가, 미혼여성의 급증, 결혼 연령의 증가 등으로 과거와는 달리 사회참여의 기회가 다양하게 증가하고 있다. 이에 따라 여성 중에 기혼 여성은 가정용 전자제품의 발달로 육아노동 및 가사노동의 감소 및 낮은 출산율을 보이고 있고, 미혼여성의 비율은 증가하는 추세에 있다. (중략)

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Evaluation of Bending Strength for Ceramic Honeycomb Using Design of Experiments (실험계획법을 이용한 세라믹 허니컴의 굽힘강도평가)

  • Kim, Jong-Kyu;Baek, Seok-Heum;Cho, Seok-swoo;Shin, Soon-Ki;Joo, Won-Sik
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
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    • v.1
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    • pp.379-384
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    • 2006
  • Since the monolithic ceramic substrate was introduced for automotive catalytic converters, the durability of the substrate has been a continuing requirement to reduce the emission gas of vehicle. The substrate can occupy a volume as small as 82 $cm^3$ and as large as 8200 $cm^3$ to provide the required substrate for catalytic activity. The long-term durability varies with the size of the substrate from manufacture's point of view. Therefore This study presents that the response surface model using central composite design can explain size effect on the modulus of rupture in a cordierite ceramic monolithic substrate.

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Development of the Standard Size Dimensions and Reference Sizes for Improving Size Suitability of Gloves (장갑치수적합성 향상을 위한 기본치수 및 참고치수 설정)

  • Kim, Eun-Kyong
    • Fashion & Textile Research Journal
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    • v.10 no.6
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    • pp.966-978
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    • 2008
  • The aim of this study was to provide size intervals in hand requisite in design of gloves. In this study, a survey was administered to gather information about glove manufacturers' sizing systems. In addition, KS glove standards' size dimensions were analyzed. As well, the ISO hand sizing system was also studied. Based on all the analyses' results, a new glove size intervals were composed. The size comprised the control dimensions of hand length and hand circumference. The size interval was 8mm in hand length and 13mm in hand circumference. The size range was established by making the coverage above 80%. The coverage of the new size interval system for an adult's hand was 86.4% and 13 sizes were suggested. The coverage of the male size system was 86.0% and 10 sizes were suggested. The coverage of the female size system was 87.6% and 8 sizes were suggested. For the unfitted gloves, size ranges based on hand length and hand circumference were developed. For the adults group, S, M, L, and XL were suggested and the coverage of the new size range was 78.8%. For the male group, S, M, and L were suggested and the coverage was 82.3%. For the female group, S, M, and L were also suggested and the coverage was 81.3%.

A Study on the Intelligent Design Method of Snap-fit in Injection Molded Part (사출제품에서 스냅핏의 지적 설계에 관한 연구)

  • 강성남;허용정
    • Proceedings of the KAIS Fall Conference
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    • 2001.05a
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    • pp.241-244
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    • 2001
  • 스냅핏은 일종의 결속장치로서 흔히 플라스틱 부품들을 서로 체결하는데 이용되는데, 다른 결속장치에 비해 간편하고 생산품의 조립단가를 줄일 수 있고, 또한 분리력은 큰 반면에 결합력은 작게 만들 수 있는 장점을 가지고 있어 널리 사용된다. 스냅핏의 설계는 재료에 따른 물성(property) 및 구조적 강성(stiffness)이 설계 초기단계에서 고려되어야 하고, 또한 사출성형공정에서 스냅핏의 성형성도 예측되어야 한다. 그러나 스냅핏의 형상, 치수, 위치 등을 적절히 설계합성(synthesis)하고 적절한 재료를 선택하는 작업은 공정에 관한 종합적인 지식을 지원해 주는 합리적인 설계도구가 제공되지 못했던 이유로 사출 전문가의 오랜 기간 축적된 경험과 지식에만 전적으로 의존하여 왔다. 본 연구에서는 기존의 전문가에 의존해온 스냅핏 설계방법을 개선하기 위해 사출성형에 의해 제한되어지는 지식을 규칙베이스화하고 재료의 물성과 스냅핏의 형상 및 치수에 파라 스냅핏이 갖는 결합력, 분리력, 변형하중 및 허용언더컷 등을 출력하는 지적 설계 프로그램을 제안하였다.