• The korean journal of orthodontics
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• v.24 no.4 s.47
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• pp.871-883
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• 1994

This experiment was designed to study possible roles of $interleukin-1\beta$, interleukin-6 and tumor necrosis $factor-\alpha$ in bone remodeling by measuring their effects on $PGE_2,\; LTB_4$ and collagenase production when they were administered to human periodontal ligament fibroblasts. Human periodontal ligament fibroblasts were collected from first premolars extracted for orthodontic treatment. They were incubated in the environment of $37^{\circ}C,\;5\%\;Co^2,\;and\;100\%$ humidity. They were treated with $0.25\%$ trypsin-EDTA solution and centrifuged. PDL cells in the fifth to seventh passage were used for the experiment. Cells were seeded onto the culture dishes and when they were successfully attached, human recombinant $interleukin-1\beta$, interleukin-6, and tumor necrosis $factor-\alpha$ were administered, alone or in combination. They were incubated for 4, 8 and 24 hours and the levels of $PGE_2,\;LTB_4$ and collagenase released into the culture media were assessed by enzymeimmunoassay and collagenase activity assay. The conclusions are as follows: 1. $IL-1\beta\;and\;TNF-\alpha$ were very active in stimulating the production of $PGE_2$ and collagenase by human periodontal ligament fibroblasts, while IL-6 increased $LTB_4$ production. 2. $IL-1\beta$ significantly increased $PGE_2$, but $LTB_4$ Production was not increased. $IL-1\beta$ is thought to act mainly via the cyclooxygenase pathway of arachidonic acid metabolism. 3. IL-6 tended to inhibit $IL-1\beta$ in the production of $PGE_2$ and collagense whereas IL-6 and $TNF-\alpha$ showed auditive effect in the level of $PGE_2$. The above cytokines increased the release of at least one of $PGE_2,\;LTB_4$ and collagenase. It suggests that cytokines are involved in bone remodeling process by stimulating PDL fibroblasts to produce various bone-resorptive agents. The roles of cytokines in bone remodeling as a whole would need further study.

• The korean journal of orthodontics
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• v.30 no.3 s.80
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• pp.287-296
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• 2000

It is well known that oral appliance could improve respiratory difficulty in patients with obstructive sleep apnea (OSA). To evaluate the effect of oral appliance, polysomnography and cephalometry were performed in OSA patients before and after oral appliance was used. Twenty four OSA patients were included in this study. Respiratory difficulty index (RDI) was obtained from polysomnography and the movement of soft palate, tongue, posterior pharygeal wall, hyoid bone, and mandible and the variables of the facial pattern were measured on the cephalogram. The changes of cephalometric parameters were compared to the RDI changes and the correlation was tested. After oral appliance was used, RDI decreased from 46.8 to 13.3. There was significant relationship between RDI improvement and the anterior movement of the mandible and superior movement of the hyoid bone. In 8 patients whose RDI was most improved, RDI improvement rate was correlated with the anterior movement of the tongue and anterior-posterior (AP) diameter of the airway at the levels between the lower portion of the soft palate and epiglottis. These results could conclude that anterior movement of the tongue and superior movement of the hyoid bone would be favorable cephalometric parameters for the improvement of OSA.

• The korean journal of orthodontics
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• v.30 no.3 s.80
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• pp.273-285
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• 2000

The aim of this investigation was to evaluate the differences of two canti-leyer springs by using a new simulation system. This was done using a Calorific machine that compared iron uprighting spring and root uprighting spring. The Calorific machine was designed to allow observation of the whole process of tooth moving, and is composed of three parts(a temperature regulating system, electro-thermodynamic teeth, and an artificial alveolar bone component). The experiment of both mechanics were repeated five times and measured two times. The intra-examiner agreement and inlet-examiner agreement were $96.54\%\;and\;95.73\%$ and these data were statistically tested by paired t-test. The obtained results were as follows. 1. Distal and buccal movement of the anchor teeth were observed greater in the root uprighting spring than the crown uprighting spring. 2. Crown uprighting spring showed distal movement of the crown of lower second molar for 3.29mm but root uprighting spring showed only 1.68mm. 3. Crown uprighting spring exhibited forward movement of mesial and distal root of the lower second molar for 3.91mm, 3.60mm but the root uprighting spring showed 6.76mm, 6.26mm.

• The korean journal of orthodontics
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• v.35 no.6 s.113
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• pp.451-458
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• 2005

Cephalometric superimposition is unable to evaluate tooth movement along the occlusal plane and the errors of photographing and superimposition of the occlusogram is also inevitable. The purpose of the present study was to evaluate the rotational movements of the maxillary posterior teeth following space closure after extraction of maxillary first premolars. using 3D dental images. In 19 adult females. analysis of rotational movements of the maxillary posterior teeth was performed between the initial and final 3D dental images superimposed on the maxillary hard palate. The results showed a diversity of rotational movements of posterior teeth. The causes of various rotational movements may be different rotation of molars in each case at the beginning of treatment. individual characters of the dental arch and tooth morphology. The results of the study indicate that accurate evaluation of rotational movements of posterior teeth following space closure after extraction of premolars using 3D dental images can be obtained through the subdivision of tooth movement during the initial aligning, space closure and finishing stages.

• The korean journal of orthodontics
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• v.25 no.3 s.50
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• pp.263-271
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• 1995

The purpose of this study nab to evlauate and compare the effect of the variable factors of wire on the elastic properties of looped rectangular wire. Five variable factors were presented-material(Hi-T, blue Elgiloy), wire size(.016'$\;\times\;$.022', .018'$\;\times\;$.025'), loop length(15mm, 20mm), loop configuration(open loop, closed loop), gabling (non-gable, gable). So, the total 256 specimens were divided into 32 groups, and each of those nab pulled on Instron testing machine. The load-deflection curve of each wire obtained, from which force, range in elastic limit, and stiffness were computed and analyzed statistically. The results were obtained as follows : 1. All of the variable factors - wire material, size, loop length loop configuration, and gabling - took a significant effect on load-deflection rate of looped wire. 2. The force at elastic limit was the smallest in the group of Hi-T, .016'$\;\times\;$.022', 20mm loop length, open loop, non-gable, and the largest in the group of blue Elgiloy, .018'$\;\times\;$.025', 15mm loop length, closed loop, non-gable. 3. The range at elastic limit was the smallest in the group of Hi-T, .018'$\;\times\;$.025', 15mm loop length, open loop, non-gable, and the largest in the group of HI-T, .016'$\;\times\;$.022', 20mm loop length, closed loop, gable. 4. Loop configuration and loop length were the most effective factors on the elastic properties of looped wires, and gabling was the least effective.

• The korean journal of orthodontics
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• v.23 no.4 s.43
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• pp.633-644
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• 1993

There has been so much controversies about the position of upper and lower jaws, and their first permanent molars in normal occlusion and Angle's class $I{\cdot}II{\cdot}III$ malocclusions. So, the purpose of this study is to compare the position of upper and lower jaws, and their first molars in normal occlusion and Angle's class $I{\cdot}II{\cdot}III$ malocclusions by lateral cephalometric analysis. The sample consisted of one hundred and twenty girls(thirty in each group) who had completed growth. The findings of this study were as follows : 1. In class I malocclusion, both maxilla and mandible were slightly posterior position than normal occlusion, but they showed harmonious relationship. 2. In class II malocclusion, the mandible was greatly retruded, and the maxilla was also slightly retruded to the cranial base as compared with normal occlusion. 3. In class III malocclusion, the maxilla was significantly retruded to the cranial base, but no significant difference was found in mandibular position as compared with normal occlusion. 4. The maxillary first molar was located at posterior position in class II malocclusion, and anterior position in class III malocclusion to the cranium, so that the rotation of mandible was influenced by that. 5. The mandibular first molar showed constant relationship to the mandible in all four groups, but different position to the cranial base in direct proportion to the mandibular position. 6. On the treatment planning of class III malocclusion, it seems to be better to promote the mandibular horizontal growth by inhibiting the vertical growth of maxillary molar area, and on the treatment planning of class III malocclusion, it seems to be better to promote the antero-inferior growth of maxilla mi to promote the mandibular vertical growth by inducing the vertical growth of maxillary molar area.

• The korean journal of orthodontics
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• v.28 no.3 s.68
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• pp.419-429
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• 1998

This study was carried out in order to study early histologic changes and repair reaction appling to extrusive force for 3rd premolar of adult dogs. After 1 week of extrusive force with elastic chain, one of dogs was sacrified and after 3 weeks retention period, another dog was sacrified. The paraffin sections of samples were stained with Hematoxylin - Eosin and Masson's Trichrome and were examed by light microscopy . The obtained results as follows 1. In Hematoxylin - Eosin and Masson Trichrome stain of control group , the periodontal ligament width was constant from apical third to cervical third of the root and periodontal fiber arrangement was horizontal or oblique in cervical third. oblique in middle third, oblique in apical third of root. in alveolar bone, smooth appearance was shown 2. In Group 1, all periodontal fiber arrangement was oblique toward tooth, and the periodontal ligament width increased Partially PDL was ruptured in apex. In MT stain, immature bone formation was seen at alveolar crest area. Active bone formation was observed along the one side of alveolus, and apical portion of pulp was involved with blood vessel rupture , vacuolization of pulp tissue and hyperemia 3. In Group 2, most periodontal ligament arrangement and PDL width was repaired and fiber density increased. In MT stain, mineralization of immature bone on the alveolar crest was progressed. In pulp, vacuole and hyperemia was diminished and fibrotic change was diminished 4. After 3 week periodontal ligament has more repair ability than pulp tissue. pulp was involved with vacuolization and fibrosis, so it takes more time for repair.

• The korean journal of orthodontics
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• v.9 no.1
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• pp.85-98
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• 1979

This investigation was designed to compare the craniofacial and dental morphology of class III malocclusion with that of normal occlusin in children, and to determine the incidence of various class III craniofacial skeletal patterns. The material selected for this study consisted in standard lateral cephalograms of eighty two Korean children, forty one boys and forty one girls, aged 10 through 12 years, having class III malocclusion, and forty two Korean children, twenty boys and twenty two girls, with normal occlusion in the same age. Using the tracings of the standard lateral cephalograms, various angular and linear measurements were recorded, tabulated and statistically analyzed, and then the class III craniofacial skeletal morphology was divided into various patterns by the degree of SNA and SNB, which respectively were below, within or beyond the normal range of those of normal occlusion. The following characteristics of the craniofacial and dental morphology of class III malocclusion were observed. 1. The cranial base length of class III malocclusion was smaller than that of normal occlusion, and the small saddle angle was a characteristic figure of class III malocclucion. 2. Maxillary length of class III malocclusion was smaller than that of normal occlusion, and point A was retropositioned relative to cranial base but not PNS in class III malocclusion. Maxillary base inclination was not significantly different between the two, but occlusal plane to palatal plane was small in class III malocciusion. 3. The mandibular body length shown no difference between the two, but the mandibular body positioned anteriorly relative to cranial base in class III malocclusion. Ramus height, gonial angle, and mandibular effective length were large in class III malocclusion. Mandibular plane angle and joint angle had no difference between the two, and occlusal plane to mandibular plane angle was large in class III malocclusion. 4. Maxillary incisor inclination was not significantly different between class III malocclusion and normal occlusion, but mandibular incisors positioned and inclined lingually and consequently interincisal angle was large in class III malocclusion. 5. Class III malocclusion was divided into six categories of craniofacial skeletal pattern. The most common class III pattern was found to be one in which the maxilla was within the normal range of prognathism while the mandible extended beyond this range. The pattern in which the maxilla was below the normal range of prognathism while the mandible was within this range was approximately one fifth of the class III sample.

• The korean journal of orthodontics
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• v.25 no.4
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• pp.425-432
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• 1995

The purposee of this study is to investigate the correlation between the horizontal and vertical discrepancy of facial bones and the horizontal and vertical position of glenoid fossa. For this study, the cephalograms were taken to the adults over 18 of age(96 men and 108women). The cephalograms were divided into three groups according to the ANB angle(below 0.5 degree, 0.5 to 4.0 degree and above 38 degree), and they were divided into three groups according to the SN-MP angle(below 30 degree, 30 to 38 degree and above 38 degree). The following conclusions were obtained : 1. In the horizontal discrepancy of facial bone(ANB), the horiontal position of glenoid fossa(X) was anterior position as the order of Class II, Class I, Cias III. 2. The horizontal position of glenoid fossa(X) showed the significant correlation with ANB and SNB, but not with SNA. 3. In the vertical discrepancy of facial bone(SN-MP), thee less anglee was the greater vertical position of glenoid fossa (X) and was followed by the medium and high angle in order. 4. The vertical position of glenoid fossa(Y) showed thhat the SN-FH was the most significant correlation, and it was followed as the order of SN-FH, SN-MP and SN-OP angle. 5. There was the samllest length of anterior cranial base in the Class III malocclusion.

• The korean journal of orthodontics
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• v.41 no.4
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• pp.280-287
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• 2011

Objective: This study compared the stability of cylindrical miniscrews (Cy, 7 mm in length) with that of tapered miniscrews (Ta, 5 mm in length), using torque values to determine if the healing time before loading affects the stability of the miniscrew and if the insertion torque is associated with the removal torque measured after a few weeks of healing. Methods: Ta and Cy with different thread lengths were placed in the tibias of 12 female New Zealand white rabbits (body weight: 3.0 - 3.5 kg), and the maximum insertion torque values (ITV) were measured. No orthodontic forces were applied so as to allow us to determine the pure effects of the different shapes. After 3 different healing periods (2, 4, and 6 weeks), maximum removal torque values (RTV) were measured immediately before the rabbits were sacrificed. Results: No miniscrews were loosened. There were no significant differences in ITV or RTV between the Ta and Cy nor were there any significant differences in the ITV and RTV between the 3 groups, which had different healing periods. There was a correlation between the ITV and RTV. Conclusions: Shorter Ta showed similar stability as Cy, as determined by torque values. This result strongly suggests that the tapered shape is more advantageous than the cylindrical shape. The RTV did not increase significantly over time. It is recommended that a miniscrew be loaded immediately; waiting a few weeks before loading should be avoided. The correlation between the ITV and RTV suggests that the ITV can be used to estimate a screw's future stability.