• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 1994.10a
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• pp.225-230
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• 1994

본 연구에서는 진동특성을 개선하기 위한 방법으로서 구조물이 가지는 공간적인 좌표를 설계변수로 하여 감도를 구하고, 이를 이용하여 구조물의 길이와 높이에 대한 형상을 변경하는 최적구조변경법에 대해 예시하고자 한다. 먼저 모우드합성법을 이용하여 임의 치수의 L형 구조물의 진동특성을 해석하고, 진동 특성을 변경하기 위해 감도해석법으로 변경할 부분의 감도를 구하여 변경할 부분의 변경량을 계산한다. 그리고 변경한 후 재해석을 통해 결과를 비교함으로써 제시한 방법의 타당성을 고찰하고자 한다.

• The Transactions of the Korean Institute of Electrical Engineers B
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• v.48 no.1
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• pp.1-6
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• 1999

Object-oriented porgramming is a major trend in computer software because it increases the flexibility of large scale software system. In this paper the advantages of the new software approach for optimal design of induction motor are demonstrated with an implementation of the motor design and characteristics analysis functions. And evolution strategy is used in optimization process.

• Annual Conference of KIPS
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• 2001.10a
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• pp.689-692
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• 2001

본 논문에서는 주어진 제약조건을 만족하며 저비용 고효율의 목적물 합성을 위하여 어느 부분을 하드웨어로 또는 소프트웨어로 구현할 것인지를 결정하는 분할 알고리즘을 제안한다. 논문[6]에서 제시한 시뮬레이티드 어닐링의 후보자 선택은 랜덤한 방식에 의해 노드의 이동이 이루어지기 때문에 중복된 후보자의 선택으로 인하여 시간이 오래 걸리는 단점이 있다. 이러한 단점을 극복하기 위해, 본 논문에서는 비용 함수를 구성하는 변수들 중에서 시스템 실행시간과 구현 비용에 영향을 미칠 수 있는 부분들을 고려해 후보자를 선택하도록 하여 최적해 탐색을 위한 분할 알고리즘의 실행 시간을 단축시켰다. 실험 결과는 대상 노드가 많아질수록 기존의 방법보다 빠른 시간에 최적의 해를 탐색한다.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1995.04a
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• pp.131-131
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• 1995

제제설계 및 컴퓨터 최적화기법을 응용하여 고형으로 바뀌는 Gel화 시간이 가장 짧은 기본처방을 구하고, Indomethacin을 주 약물로하여 약물방출에 영향을 줄 수 있는 PVA, PEG 및 Ethanol 을 독립변수로, 약물방출속도를 종속변수로 하여 중심 합성계획법에 따라 실험을 행하여 최적처방을 구한다. 최적처방에 의한 Soft Hydrogel 을 제조하여 약물방출속도 및 Rheometer 에 의한 유동특성을 측정하였다.

• Journal of the Korean Society of Food Science and Nutrition
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• v.46 no.9
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• pp.1122-1127
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• 2017

Currently, the consumer trends are increasing towards "natural" in all food systems. Therefore, in the flavor industry, the production of flavor esters by "natural" methods are needed. On the other hand, "natural flavor" is expensive to produce because of the limited natural source. Recently, the flavor obtained from the enzyme or microbial could be represented as "natural flavor". Ethyl butyrate is used most frequently as a fruity aroma in drinks and the processed food industry. In this study, ethyl butyrate was synthesized enzymatically using the ester synthetase obtained from the waste of pineapple and banana peel. The ethyl butyrate production optimization was analyzed using a response surface methodology. The enzyme reaction variances were composed of the ethanol content, butyric acid content, and reaction time. As a result, in ester synthetase obtained from banana peel, the maximum predicted production amounts were 45.8199 mM at an ethanol content of 38.7050 mM, butyric acid content of 50.9019 mM, and reaction time of 4.3662 h. In ester synthetase obtained from pineapple peel, the maximum predicted production was 65.1087 mM at an ethanol content of 54.6502 mM, butyric acid content of 58.7638 mM, and reaction time of 4.7436 h. In conclusion, ethyl butyrate production was shown the more useful using the ester synthetase obtained from pineapple peel than that from banana peel.

• Applied Chemistry for Engineering
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• v.33 no.4
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• pp.402-407
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• 2022

Statistical design of experiments was used to optimize the MOF-5 synthesis process. A mixture design was employed to optimize precursor concentration. The optimal composition of three chemical materials, terephthalic acid, zinc acetate dihydrate, and N,N-dimethylformamide for MOF-5 synthesis was determined by extreme vertices design methods as follows; 1 mol : 2.7 mol : 40 mol. A multilevel factorial design was selected to screen the significance of synthesis reaction conditions such as temperature, time, and stirring speed. Statistical analysis results suggested excluding stirring speed from further investigation. Using a central composition design, the synthesis time and temperature were optimized. The quadratic model equation was derived from 13 synthesis experiments. The model predicted that MOF-5 synthesized at 119 ℃ for 10.4 h had the highest crystallinity.

• Food Industry And Nutrition
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• v.2 no.1
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• pp.7-9
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• 1997

내열설 미생물, Thermus caldophilus CK24에 대한 탄수화물 생합성을 연구하는 과정에서 다양한 탄수화물 관련효소를 탐색하고 그레 대한 생화학적 및 분자생물학적 연구를 수행하고 있다. 일차로 내열성 미생물내 1) 당핵산염 합성효소와 당전이 효소, 2) 탄수화물 대사효소. 3)탄수화물 분해 및 전환효소의 존재를 HPLC/Bio-LC분석을 통하여 확인하고 이들에 대한 연구를 진행하고 있다. 본 연구발표에서는 포도당을 과당으로 전환하는 이성화효소(xylose isomerase), 그리고 맥아당을 트레할로스로 전환하는 트레할로스 합성효소(trehalose synthase)를 소개하고저 한다. 이성화효소는 이미 산업적 과당 생산에서 대규모적으로 사용되고 있는 식품산업효소이다. 본 연구에서는 Thermus caldophilus GK24, Thermus thermophilus HB8, Thermus flavus AT62 3종의 내열성 미생물에 대한 이성화효소 유전자를 클로닝 하고, 각 재조합하고 이성화효소를 대량생산하였다. 이 내열성 이성화효소는 최적 반응 온도가 8$0^{\circ}C$이고, 포도당을 과당으로 전환하는 수유른 55%이었다. 이러한 과당전환률은 이미 산업적으로 사용되고 있는 이성화효소의 과당전환률(43%)보다 훨씬 높은 것으로 과당 생산공정의 단순화의 생산성 향상에 결정적인 요인이라 할 수 있다. 한편 본 이성화효소의 산업적 특성을 증대하기 위하여 구조-기능관계 연구를 착수하였다. 우선 내열성 이산화 효소의 입체 구조를 결정하였고, 구조조정에 따른 기능적 특성을 조사하기 위하여 특정 위치의 선택적 변이 연구를 진행하고 있다. 끝으로 포도당 전이 효소를 추적하던 과정에서 맥아당을 트레할로스로 전환하는 새로운 효소를 Thermus caldo-philus GK24에서 발견하였다. 그 트레할로스 합성효소는 분자량이 약 110kDa이고 최적 반응온도가 75$^{\circ}C$이면, 조효소없이 맥아당을 트레할로스로 80%이상 전환해 주는 가역효소이었다. 본 연구에서는 효소반응의 조건과 특성을 조사하였고, 효소 아미노-밀단의 서열결정정보를 통하여 효소의 유전자를 클로닝 하고 그 유전자의 구조와 발현연구를 진행하고 있다.

• Nuclear Engineering and Technology
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• v.25 no.1
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• pp.148-153
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• 1993

A fifth-order Fourier series technique is applied in Core Operating Limit Supervisory System (COLSS) to construct the on-line core average axial power shape from in-core detector signals because of its simplicity and fast computation. Such a synthesizing accuracy depends on number of Fourier series modes and axial boundary conditions. COLSS currently uses the five-mode Fourier series technique which utilizes the five axially located fixed in-core detector signals and a constant axial boundary condition. Therefore, the constant axial boundary condition should be appropriately chosen based on the evaluation of its effect on the accuracy of the on-line calculations. The four cases of axial buckling (0.75, 0.8, 0.9 and 1.0) were examined for Yonggwang Nuclear Units 3&4 as the axial boundary conditions in this paper. The core average axial power shapes and the operating margins were compared for each case to determine the optimal constant axial buckling. The axial buckling of 0.9 was found to be the optimal value.

• Applied Biological Chemistry
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• v.35 no.5
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• pp.339-345
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• 1992

In order to enhance the processing quality and utility of alaska-pollack meat, the optimum conditions for the preparation of pronase hydrolysate and the synthesis of plastein were investigated. The optimum temperature and pH for the hydrolysis of alaska-pollack by pronase were $40^{\circ}C$ and pH 7.0. The reaction time and enzyme concentration were 4 hr and 1,000 units per g of substrate. Under the above optimum conditions alaska-pollack was hydrolyzed by pronase yielding a hydrolytic degree of about 89%. Pronase hydrolysate was employed as substrate for plastein synthesis. The 30% pronase hydrolysates were adjusted to pH 7 for fruit-bromelain and pH 5 for stem-bromelain, and then plastein were synthesized by 1% bromelain at $40^{\circ}C$ for 24 hr. The plasteins synthesized by fruit- and stem-bromelain were consisted of peptides having average peptide length of 22.6 and 20.8 under the optimum synthetic conditions. The plastein synthesis reaction reduced considerably the bitterness of pronase hydrolysate.

• KIPS Transactions on Computer and Communication Systems
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• v.8 no.11
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• pp.271-276
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• 2019

Conventional ARIA algorithm which is used LUT based-S-Box is fast the processing speed. However, the algorithm is hard to applied to small portable devices. This paper proposes the hardware design of optimized ARIA crypto-processor based on the modified composite field S-Box in order to decrease its hardware area. The Key scheduling in ARIA algorithm, both diffusion and substitution layers are repeatedly used in each round function. In this approach, an advanced key scheduling method is also presented of which two functions are merged into only one function for reducing hardware overhead in scheduling process. The designed ARIA crypto-processor is described in Verilog-HDL, and then a logic synthesis is also performed by using Xilinx ISE 14.7 tool with target the Xilnx FPGA XC3S1500 device. In order to verify the function of the crypto-processor, both logic and timing simulation are also performed by using simulator called ModelSim 10.4a.