• Journal of Sasang Constitutional Medicine
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• v.13 no.1
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• pp.61-69
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• 2001

사상의학적 견지에서 태음인(太陰人)의 중풍, 치매와 같은 신경계질환에 다용되고 있는 열다한소탕(熱多寒少湯)은 최근에 그 임상적 효과를 뒷받침할 다각적인 연구들이 이루어지고 있음에도 불구하고 그 정확한 약리학적 기전에 대해서는 밝혀지지 않고 있다. 본 연구에서는 인간성상세포를 이용하여 열다한소탕(熱多寒少湯)이 substance P (SP)와 lipopolysaccharide (LPS)에 의해 유도되는 다양한 세포활성물질의 분비량의 조절을 검토함으로써 열다한소탕(熱多寒少湯)의 약리기전을 면역학적 측면에서 보다 세밀하게 살펴보고자 하였다. 열다한소탕(熱多寒少湯) 수침액은 인간 뇌 성상세포로 부터 LPS와 SP의 동시자극에 의해 생성되는 세포활성물질중 interleukin (IL)-1, IL-4, IL-6 및 tumor necrosisfaccor-${\alpha}$ (TNF-${\alpha}$)의 분비를 농도의존적으로 억제했다. 그러나 interferon-${\gamma}$ (IFN-${\gamma}$) 및 IL-2의 분비 조절에는 영향을 미치지 않았다. 그리고 항 IL-$1{\beta}$ 항체에 의해 SP 유도성 TNF-${\alpha}$ 분비의 증가가 억제되기 때문에 IL-1은 TNF-${\alpha}$ 증가를 매개하는 역할을 하는 것으로 사료된다. 이상의 결과는 열다한소탕(熱多寒少湯)에 의한 급성기 중풍환자 치료 효과가 뇌 성상세포로부터 분비되는 세포활성물질의 조절과 밀접한 관련성이 있다는 것을 암시하고 있다.

• Perspectives in Nursing Science
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• v.9 no.1
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• pp.1-8
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• 2012

Purpose: The purpose of this study was to compare variables related to weight control between normal weight and overweight/obese female adolescents. Methods: This study is a supplementary analysis using a total of 293 female adolescents in Seoul. Data were collected through self-report questionnaires on the topics of stages of change, processes of change, and the decisional balance pertaining to weight control. Body weight and height were also measured. Results: There was a significant difference in the stages of change between the normal weight and overweight/obese groups. Of 12 processes of change, 9 processes were significantly higher in the overweight/obese group than in the normal weight groups. Also, female adolescents who were overweight or obese had significantly higher pros and eating efficacy scores comparing to those in the normal weight group. Conclusion: The findings of this study suggest that overweight/obese female adolescents, especially those in the action stage need supports to continue their weight control behaviors. In addition, a weight control program for female adolescents should emphasize their participation in physical activities in addition to their dietary control efforts.

• Journal of Digital Convergence
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• v.11 no.11
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• pp.509-519
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• 2013

The purpose of this study was to identify the factors related to awareness, treatment, and control of hypertension in Korea using data from the 4th KNHANES. The analytical technique employed multivariate logistic regression analysis and the major findings of this research are as follows. First, awareness of hypertension was positively associated with age, occupation, self-rated health, Body Mass Index, and health examination since 2 years ago, in both males and females. Second, treatment of hypertension was positively associated with age, self-rated health, Body Mass Index, and health examination since 2 years ago, in both males and females. Third, control of hypertension was positively associated with age, self-rated health, Body Mass Index, and health examination since 2 years ago, in both males and females. Finally, the results of analysis suggest that the government should especially focus on the vulnerable group and continue to strengthen effective efforts for improving awareness, treatment, and control of hypertension.

• Journal of Korean Medicine Rehabilitation
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• v.15 no.1
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• pp.67-75
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• 2005

목 적 : 면역 세포에서 주로 생성되는 사이토카인인 인터루킨-1 (interleukin-1)은 다양한 신경내분비계와 대사 기능에 영향을 미치며, 비만인의 말초혈액 단핵구에서 증가하는 경향이 있는 것으로 연구보고 되고 있다. 본 연구의 목적은 $IL-1{\alpha}$ 다형성과 사상체질이 비만과 관련이 있는지를 조사하는데 있다. 연구방법 : 본 연구에서는 현저한 체질량지수 (body mass index, BMI) 다양성을 보이는 건강한 한국 여성 182명을 대상으로 $IL-1{\alpha}$ 유전자형을 분석하였다. 결 과 : T 대립 유전자는 BMI 감소와 관련이 있었다. BMI $27-30kg/m^2$ 그룹(group III)에서 T 대립유전자의 빈도는 $25kg/m^2$ 미만의 그룹(group I)에 비하여 유의하게 감소하였다 (odds ratio, OR, 0.141; 0.25% CI, 0.04-0.54). 더욱이 태음인 여성에서 $IL-1{\alpha}$ T 대립유전자의 빈도가 normal group에 비하여 overweight group (BMI $27-29kg/m^2$)에서 명확하게 감소하였다 (OR, 0.139; 95% CI, 0.04-0.54). 결 론 : 본 연구에서 175명의 체질분석결과 $BMI{\geq}25$인 군들의 태음인의 빈도가 높았으며, BMI는 CC genotype를 가진 사람에서보다 CT+TT genotype를 가진 사람에게서 더 낮았다. 태음인에서 동형접합 또는 이형접합 T 대립유전자가 $BMI{\geq}25$인 군에서 유의하게 감소하였다. 이상의 결과는 한국 여성에서 $IL-1{\alpha}$ 유전자 조절부위에 위치한 -889C/T 다형성과 비만 및 사상체질의 관련되는 것을 의미한다.

• Korean Journal of Psychosomatic Medicine
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• v.18 no.1
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• pp.40-47
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• 2010

Objectives：Body image is closely related to self-esteem and weight-control related behaviors. In particular, relationship between two factors would be stronger in female adolescents. False recognition on body image and weight can be a risk factor of eating disorder, depression, and suicidal ideation. This study aimed to examine the effects of body image and eating disorders on developing depressive symptoms and suicidal ideation in female adolescents. Methods：Two hundred thirty nine students of a Girls' Commercial High School in Seoul were recruited. Eating Attitude Test for Korean Adolescents, Self-Esteem Scales, Impulsiveness Scale, Beck's Depression Inventory and Beck's Suicidal Ideation Scale were used to measure eating attitude and severity of psychiatric symptoms. Results：Among 239 subjects, the estimated risk group of eating disorders was 10%(n=24). They experienced more depressive symptoms than the control group. The bigger discrepancy in current and ideal body mass index was significantly related with higher depressive mood, suicidal idea, abnormal eating habits and lower self-esteem. Discrepancy between current and idea BMI was the most meaningful predictive factor about depression and suicidal thoughts by linear regression analysis. Conclusion：In spite of normal weight range of enrolled subjects, they experienced significant depressive mood, suicide thoughts and lower self-esteem associated with the discrepancy of their own subjective body image and current body mass index. Hence educational approach regarding normal body image and healthy weight control is needed for their mental health and preventing eating disorder.

• Journal of Industrial Convergence
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• v.22 no.5
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• pp.79-88
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• 2024

The study aim was to investigate the relationship between adolescents' physical activity and subjective health perceptions and determine whether body mass index (BMI), an obesity-related indicator, had a mediating or moderating effect on this relationship. To achieve the purpose of this study, raw data from the 18th Youth Health Behavior Online Survey (2022) were used, and data from 23,612 people were ultimately selected for the research analysis. A confirmatory factor analysis and structural equation modeling were applied to the data, and bootstrapping techniques were used to verify the mediating effect. To verify the moderating effect, a multigroup analysis of the structural equation model was applied to calculate pairwise parameter comparison values. All statistical significance levels were set at .05. The results of this study follow. First, the greater the amount of physical activity among adolescents, the more positive was the effect on subjective health perception. Second, subjective body type perception had a partial mediating effect on the relationship between physical activity and subjective health perception. Third, subjective body type had a moderating effect on physical activity and subjective health perception. Specifically, people who perceived their subjective body types as average viewed their subjective health more positively when they engaged in more physical activity than those who perceived their body types as slightly or very overweight. In conclusion, preventing obesity and positively changing the subjective health status through sufficient physical activity during adolescence are important.

• Journal of the Korean Society of Food Science and Nutrition
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• v.34 no.9
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• pp.1381-1387
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• 2005

This study was intended to evaluate the weight control program for 18 obese female college students during 9 weeks. The weight control program was composed of periodical counsel for self-control of dietary attitude and exercise with personal/group program. The female college students were average 21.3 years old and average 161.8 cm of height. The subjects were classified into 2 groups based on BMI: overweight group $25\le{BMI}<27$, obese group BMI$\ge$27. The subjects were average 71.56 kg of weight and $27.25 kg/m^2$ of BMI before they joined the program. The prompt of joining was less self-confidence for appearance. After 9 weeks, the overweight group lost their weight about 3.28 kg and also reduced 1.61 percentage of body fat. The obese group also lost their weight about 3.0 kg but reduced only 0.8 percentage of body fat. The serum levels of total cholesterol and LDL-cholesterol dropped significantly (p<0.05) in the overweight group. The $VO_2$ max inclosed 2.71 mL/kg/min in the overweight group. The obese group reduced caloric intakes from $109.2\%\;to\;86.5\%$ of RDA. The scores of dietary attitude such as eating speed, snack frequency, watching TV or reading during the eating were significantly increased (p<0.05) in obese group. These overall results suggest this program would be effective in self-weight control of overweight people. But the obese group assumed negative attitude in self-exercise program. So it is necessary to manage weight control programs, as considering obesity degree of subjects.

• Journal of Sasang Constitutional Medicine
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• v.10 no.2
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• pp.589-613
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• 1998

The purpose of this research was to investigate effects of Bangpoongtongsungsan water extract(BTSE) on the immune reaction, anti-allergy action and anti-inflammatory action in BALB/c mice. The administration of BTSE (500mg/kg) enhanced the cell viability of thymocytes and the population of helper T cells in splenic T-lymphocytes. BTSE suppressed the production of nitric oxide, but enhanced the phagocytic activity in peritoneal macrophages. BTSE enhanced hemagglutination titer in mice. BTSE inhibited passive cutaneous anaphylaxis induced by egg albumin in rat, the lethal anaphylaxis induced by platelet activating factor and compound 48/80 in mice, and then inhibited the degranulation of peritoneal mast cells induced by compound 48/80. BTSE did not inhibit Arthus reaction, but inhibited the delayed type hypersensitivity induced by SRBC and contact dermatitis induced by DNFB. BTSE inhibited the acute hind paw edema induced by histamine after 30 minutes, the permeability of evans blue into peritoneal cavity induced by acetic acid and the writhing syndrome induced by acetic acid. These results suggest that BTSE has an immunopotentiative action, anti-allergy action and anti-inflammatory action via the inhibition of histamine release.

• Journal of Sasang Constitutional Medicine
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• v.10 no.1
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• pp.1-11
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• 1998

Constitution means to combine the function into the body. It also includes the genetic factor and the environmental factor. Sasang Constitutional Medicine has the organized and unique ideas of the theory and the practice. So it is widly used in korea. But It has a problem to be popular. That's the objectification of Sasang constitution. There are so many studies to classify Sasang constitution analytic and objectively. I try to classify the studies to identify Sasang constitution objectively and check the problems. 1. The morphologic studies of Sasang Constitution are dividied into the figure and the face-speech through the morphologics and the phonetics. We need to standardize and make a simple method through computer software. 2. The study of the mind is used by the questionnaire about the telent, the character, and the greed each constitution. Recently QSCC II computer software is made and is used at many clinics in Korea. We need to recheck children and Taeyangin. 3. The symptom and the disease are subjective. So the study of them is usually used by some diagnostic equipments. But these have to be revaluated on the view of Oriental Medicine and Sasang Constitutional Medicine and try to study the objectification of Sasang constitution. And then we must try to objectify Sasang constitutional disease. 4. Disease and symptoms have to be studied much more about the mechanism and the relation. The study of medicine was done the way of the homeopathy using EAV. But that had some problems. So it should depend on the new science.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.25 no.1
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• pp.37-54
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• 1999

Planarized SiO$_2$ particles were prepared by two-step reduction method of making much smaller particles, micron-sized ones, to improve spreadability, adherence, and smoothness. Various pigments known as flaky extender usually have terrace layers on their surfaces, but SiO$_2$ Particles in this study exhibit a smooth surface structure. These single SiO$_2$ particles were used for core particles to prepare the composite particles coated with ultra fine TiO$_2$ particles by a homogeneous precipitation method. The thickness and the morphology of the deposited TiO$_2$ layer could be altered by adjusting the reactant concentrations, reaction time and temperature. The characteristics of SiO$_2$/TiO$_2$composite in the field of color cosmetics is to give a UV-cut effect and to enhance the chroma of human skin color, one of optical properties.