• The Journal of Internal Korean Medicine
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• v.21 no.4
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• pp.575-581
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• 2000

Objective : Asthma is a lung disorder characterized by periodic attacks of wheezing alternating with periods of relatively normal breathing. And quality of life in asthmatic patients shows a tendency to decrease. So we had a clinical study whether if oriental medical treatment could improve their quality of life or not. Methods : The 15 cases were new patients that visited at division of respiratory system, department of internal medicine in Kyunghee medical center from the 1 st of July, 2000 to the 1 st of August. All of them were diagnosed as asthma and treated by western medical therapy. We used a Quality of Life Questionnaire for adult Korean Asthmatics(QLQAKA) and evaluated the results after two times answers, at an interval of two weeks. Results : The mean of the first answer was 2.84 marks and 3.36 ones after two weeks. If there is a difference of over 0.5 points between the two, we can admit significant effect. After the asthmatic patients treated by oriental medical therapy, they gained a difference of 0.52 points, 10.4%. Conclusions : We suggest that oriental medical therapy can improve the quality of life of asthmatic patients arid we can alternate side effects of western medical therapy with oriental one. if they carry out two different treatments at the same time.

• The Journal of Korean Medicine
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• v.24 no.3
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• pp.184-191
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• 2003

Background : Nowadays asthma is considered to be an inflammatory disease characterized by airway hyperresponsiveness and pulmonary eosinophilia. Production of cytokines by bronchial epithelial cells may contribution to the local accumulation of inflammatory cells in patients with bronchial asthma. Chungsangboha-tang is the herbal treatment of choice in persistent asthma patients. It has been recognized that cessation of treatment with Chungsangboha-tang evokes a recurrence of symptoms in patients with controlled asthma. This study was designed to evaluate the long-term effect of Chungsangboha-tang. Materials and Methods : The subjects consisted of 24 patients with asthma who had been treated with Chungsangboha-tang for four weeks. Chungsangboha-tang is an herbal decoction which has been used as the traditional therapeutic agent for asthma. PFT, QLQAKA, blood eosinophils, serum IgE, Serum IL-4, IL-5, $IFN-{\gamma}$ were checked before treatment, before withdrawal and 3 months after cessation of treatment with Chungsangboha-tang. Results : Treatment with Chungsangboha-tang for four weeks resulted in significant increase in FEV1.0%, PEFR%, and QLQAKA. The patients were treated with Chungsangboha-tang for four weeks with no significant difference in the blood eosinophils, serum IgE, IL-4 and IL-5. The serum $IFN-{\gamma}$ in asthmatic patients decreased significantly after 4 weeks of treatment. Discontinuation of treatment with Chungsangboha-tang resulted in significant drops in QLQAKA. Others measures in asthmatic patients 3 months after discontinuation of treatment with Chungsangboha-tang showed no significant difference. Conclusion : This study demonstrates that asthma can be exacerbated by discontinuation of treatment with Chungsangboha-tang in patients with asthma. Obviously further research concerning this is still necessary.

• Tuberculosis and Respiratory Diseases
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• v.51 no.6
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• pp.585-589
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• 2001

Pneumoperitoneum, Pneumomediastinum, subcutaneous emphysema and a pneumothorax are some of the mechanical complications of bronchial asthma. The incidence of pneumoperitoneum during an attack of acute asthma is rare. The pathogenesis is free gas track from the overdistended alveoli, through the bronchovascular sheaths to the mediastinum. If the high pressure is maintained, air can escape retroperitoneally into the abdomen and burst into the peritoneal cavity. A 43-year-old woman was admitted due to a severe asthma attack. She was required endotracheal intubation and AMBU(air mask bag unit) ventilation. Immediately after these procedures, pneumoperitonewn, pnewnomediastinwn, and subcutaneous emphysema developed. She was treated with mechanical ventilation and medical therapy. The pneumoperitonewn was resolved after 27days. Here, we report this case with the review of the relevant literature.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.17 no.3
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• pp.371-381
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• 2010

Purpose: The purpose of this study was to develop a scenario and evaluate students' performance in simulation learning of care for patients with asthma in emergency units. Methods: Meetings of experts were used to develop a scenario based on actual patients and textbook material. An evaluation protocol was developed to evaluate the simulation learning. The scenario was used in 2006 with six groups of 26 senior nursing students who participated voluntarily. Results: The scenario was developed according to the nursing process for 15 minutes of simulation learning. The nursing students were able to demonstrate their knowledge and skills. The results showed a need to improve problem solving ability. In the self-evaluation, the students reported that simulation learning helped them to integrate their knowledge to practice and recognize their weaknesses and strengths. However, the scores for self-confidence about patient care after the simulation learning were low (4.8/10). Conclusion: The scenario in this study gave the students the experience of providing qualified and secure nursing care under conditions similar to reality. Further development of a variety of scenarios for simulation learning is needed.

• Analytical Science and Technology
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• v.17 no.1
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• pp.53-59
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• 2004

Up to now, methods for the detection of genetic alterations as single strand conformation polymorphism (SSCP) or denaturing gradient gel electrophoresis (DGGE) have been used. It is too labor-intensive and expensive to serve for routine analysis. Moreover, lower in its sensitivity and specificity being also strongly dependent on the experience of the investigater. To improve these problems, we analysed mutation of ${\beta}_2$-adrenergic receptor gene that controls bronchial asthma by denaturing high performance liquid chromatography (DHPLC) according to ion-pair reversed phase chromatography (IP-RPC). We extracted genomic DNA from 80 asthma patients and then amplified DNA using PCR and analysed PCR product by SSCP and DHPLC. As a result, we analysed mutation frequency is 19 (23.75%) on SSCP and 25 (31.25%) on DHPLC in ${\beta}_2$-adrenergic receptor gene. We conclude that DHPLC is a fast and simple screening method rather than SSCP analysis.

• Korean Journal of Clinical Pharmacy
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• v.34 no.3
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• pp.194-201
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• 2024

Background: Asthma is a chronic inflammatory airway disease associated with systemic inflammation and increased prevalence of various comorbid conditions. This study investigates the prevalence of non-respiratory comorbidities among adult asthma patients in South Korea, aiming to elucidate potential correlations and impacts of asthma on overall health, thereby affecting patients' quality of life and healthcare systems. Methods: This retrospective cohort study utilized the National Health Insurance Service data (HIRA-NPS-2020) and included adults diagnosed with asthma. Non-respiratory diseases were identified using the Korean Standard Disease Classification (KCD-8) codes, with exclusions applied for other respiratory conditions. The prevalence of comorbidities was analyzed and compared between asthma and non-asthma patients, adjusting for confounders such as age, gender, and insurance status through inverse probability treatment weighting (IPTW). Results: The analysis revealed that asthma patients exhibit significantly higher rates of cardiovascular diseases, metabolic disorders, gastrointestinal conditions, and mental health issues compared to the control group. Notably, conditions such as heart failure, gastroesophageal reflux disease, and anxiety were more prevalent, with odds ratios (OR) ranging from 1.18 to 3.90. These results demonstrate a substantial burden of comorbidities associated with asthma, indicating a broad impact on health beyond the respiratory system. Conclusion: The findings highlight the systemic nature of asthma and the interconnectedness of inflammatory processes across different organ systems. This comprehensive analysis confirms previous research linking asthma with an increased risk of various non-respiratory diseases, providing insights into the multifaceted impact of asthma on patient health.

• Journal of Sasang Constitutional Medicine
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• v.14 no.1
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• pp.112-117
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• 2002

An Athma is a hypersensitive reaction of bronchus on various stimulus. It has a cough and laboring breath caused by narrowing of inflammatory bronchus. In this study, the three asthma patients classified by Sasang constitutional medicine had a notable medical effects. So we report the healing process and results of these three patients in this study.

• The Korean Chronic Disease News
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• no.317
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• pp.1-18
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• 2007

경북 고령군 보건소 안순기 소장/“만성질환관리 건강투자 전략의 핵심”/‘보호자 없는 병원’시범사업/치매?뇌혈관질환?파킨슨병 등/“만성질환관리는 미래의료의 핵심”/한방보건 최우수기관‘익산보건소’/공공보건 EHR선진화 1577억 투입/전국비만학회연합회 비만 가이드라인 제시/맞춤의학 실현 KARE 프로젝트 착수/“신약개발.보건의료 연구투자 협력”/지난해 국내 의약품 생산 12조원 돌파/식욕억제제 관리 위반 의원?약국 적발/“well-dying”...사랑의 공동체 실현/가정호스피스.완화의료사업/신장내과 외래환자 58.4%가 40~60대/“천식 등 호흡기질환 예방관리 총력”/WHO 국제암연, 학술위원에 방영주 교수/30대 이상 70% 남성‘성관계’실패 경험/부실한 인적 자본, 미래 위한 건강투자 시급/2005년 시도별 생명표 및 사망원인통계 결과/유럽 고혈압학회 가이드라인 업데이트/

• Journal of Korean Medicine Rehabilitation
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• v.25 no.3
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• pp.103-109
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• 2015

Objectives The objective of this study si to report clinical effect of korean medical treatments and Buteyko breathing technique for asthma patient with pneumonia. Methods The patient was treated by korean medical treatment including acupunture, moxibustion, herbal medication and Buteyko breathing technique. The improvement of clinical symptoms was observed by visual checking and X-ray, Pulmonary Function Test that index include TV, FVC, FEV1. Results After treatments, the patient was improved in visual checking and X-ray on chest, TV, FVC, FEV1. Conclusions We suggest that korean medical treatment and Buteyko breathing technique could be an effective method to improve the asthma patient with pneumonia.

• The Journal of Internal Korean Medicine
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• v.39 no.2
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• pp.184-191
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• 2018

Objectives: This study evaluated the effects of traditional Korean medicine treatment on a patient with asthma. Methods: A patient was treated with acupuncture, herbal medicine, and cupping. The effect of treatment was evaluated via the quality of life questionnaire for adult Korean asthmatics (QLQAKA), the visual analog scale (VAS), and night awakening frequency. Results: After treatment, improvements were observed. The total QLQAKA score increased from 36 to 50. Conclusions: This study observed that traditional Korean medicine treatments are effective in caring for a patient with asthma.