• Title/Summary/Keyword: 창상(創傷)

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Effects of Chitosan on Wound Healing in Pigs (돼지에서 창상치유에 대한 키토산의 영향)

  • Byun, Hong-Sub;Kim, Myung-Jin;Lee, Jae-Yeon;Cho, Sung-Whan;Park, Chang-Sik;Kim, Myung-Cheol
    • Journal of Veterinary Clinics
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    • v.24 no.2
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    • pp.114-118
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    • 2007
  • The objective of this study was to investigate the effects of implanted chitosan applied to surgically created wound in pigs. Six healthy $2{\sim}3$ months old Landrace and Yorkshire mixed breeds of both genders were used. A 2 cm straight skin incision was made and undermined skin ($2{\times}2cm$) over on the each pig's both sides of dorsal midline at 0, 7. 14 and 18 days. One wound (left side) was implanted 0.4 mg of cotton type chitosan and other wound was treated saline (3 ml). Each wound was closed with two interrupted suture of 2-0 sutures. The wounds created at 18, 14.7 and 0 days were named post-wounding day (PWD) 3, 7, 14 and 21, respectively. At 21 days after initial wounding, each wound was taken for histological observations. Reepithelialization tended to be greater in the chitosan group than in the control group at PWD 3 and 14. Granulation tissue formation did not show especial differences in two groups. Number of inflammatory cells was lesser statistically in level in the chitosan group than those in the control group at 21 days after wounding (p<0.05). Fibroblasts and neovasculature tended to be greater in the chitosan group than in the control group at PWD 3 and 7, and tended to be lesser in the chitosan group than in the control group at PWD 14 and 21. Collagen and fibrin were observed to be evenly distributed around the wound in the chitosan group. But collagen and fibrin were observed to be converged along the wound in the control group.

The Current Status of Bacterial Identification by Wound Culture for Diabetic Foot Lesions in a Single Tertiary Hospital in South Korea (단일 3차 의료기관에 내원한 당뇨병성 족부병변 환자의 창상 배양검사를 통한 세균 검출 현황)

  • Jung, Sung Yoon;Lee, Myoung Jin;Lee, Seung Yup;Lee, Sang Yoon
    • Journal of Korean Foot and Ankle Society
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    • v.25 no.2
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    • pp.100-107
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    • 2021
  • Purpose: The present study aimed to develop guidelines regarding initial choice of antibiotics for diabetic foot ulcers (DFU) by investigating bacterial isolates. Materials and Methods: This study included 223 DFU patients that visited a single tertiary hospital and underwent bacterial culture between January 2016 and February 2020. The study was conducted in two parts: 1) to compare bacterial isolates and wound healing according to comorbidities such as chronic kidney disease (CKD) and peripheral artery disease (PAD), and 2) to compare bacterial isolates according to wound depth using the Wagner classification. Results: Of the 223 patients, 43 had CKD (group A), 56 had PAD (group B), 30 had CKD and PAD (group C), and 94 had none of these comorbidities (group D). The isolation rate for multidrug-resistant gram-negative bacteria (MRGNB) and gram-negative to gram-positive bacteria ratio were highest in group C (p=0.018, p=0.038), and the proportion that achieved wound healing was lowest in group C (p<0.001). In the second part of the study, subjects were classified into 5 grades by wound depth using the Wagner classification; 13 grade I, 62 grade II, 60 grade III, 70 grade IV, and 17 grade V. No significant difference was observed between these grades in terms of isolation rates or gram-negative to gram-positive bacteria ratios. Conclusion: This study suggests antibiotics that cover gram-negative bacteria including MRGNB produces better results in the presence of CKD and PAD and that initial antibiotic choice should be based on the presence of CKD and PAD rather than wound depth.

Reconstruction of a Circumferential Penile Shaft Defect Using Bilateral Superficial External Pudendal Artery Perforator Flaps (양측 천외음부동맥 천공지 피판을 이용한 음경둘레 연조직 결손의 재건)

  • Park, Jongohk;Shin, Donghyeok;Choi, Hyungon;Kim, Jeenam;Lee, Myungchul
    • Archives of Hand and Microsurgery
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    • v.23 no.4
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    • pp.296-300
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    • 2018
  • Penile shaft reconstruction requires adequate soft tissue characteristics as well as constant vascular pedicles when considering a perforator flap. The free flap technique using various donor sites and regional conventional and perforator flaps have been utilized for penile shaft reconstruction. Still, the free flap techniques include challenging surgical procedures in addition to postoperative management. The regional flap can be applied to limited defects due to the size and shape. We performed the bilateral superficial external pudendal artery (SEPA) perforator flaps in order to reconstruct a circumferential penile shaft defect. The circumferential wound has noted necrotic tissue involving superficial (Dartos) fascia. We underwent debridement, preserving deep (Buck's) fascia and corpus spongiosum. Thereafter, the soft tissue defect was covered with bilateral SEPA perforator flaps. The patient has been observed for 27 months, showing penile resilience without deformity or wound-related problems.

The Development of N2O Emission Factor at Killn Type Pyrolysis Melting Facility (외열킬른형 열분해용융시설의 N2O 배출계수 개발)

  • Yun, Hyun-Ki;Lee, Dae Kyeom;Cho, Changsang;Kang, Seongmin;Yoon, Young joong;Jeon, Youngjae;Jeon, Eui Chan
    • Journal of Climate Change Research
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    • v.8 no.3
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    • pp.231-237
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    • 2017
  • In this study, the $N_2O$ emission factor of the facility was developed by measuring the kiln type pyrolysis melting facility. This used PAS (Photoacoustic Spectroscopy) method and measured the $N_2O$ emission concentration. From March 2016 to April 2016, it was measured over a total of two times and $N_2O$ concentrations were measured continuously for 24 hours using a 24 hour continuous measuring instrument (LSE-4405). The measured $N_2O$ emission concentration of the pyrolysis melting facility was 0.263 ppm on average and the emission concentration distribution in the range of 0.013~0.733 ppm was obtained. Therefore, the $N_2O$ emission factor of the kiln-type pyrolysis melting facility was estimated to be $0.829gN_2O/ton$-Waste. As a result of comparing the $N_2O$ emission factor of the thermal kiln type pyrolysis melting facility and the previous study, previous studies were about 18 times higher. It is estimated that this is due to the difference of furnace temperature, oxygen concentration and denitrification facilities. It is considered that the study of the emission factor of pyrolysis melting facility is an important factor in improving the credibility of greenhouse gas inventory in waste incineration sector.

Comparison of N2O Emissions by Greenhouse Gas Emission Estimation Method (온실가스 배출량 산정 방법에 따른 N2O 배출량 비교)

  • Kang, Soyoung;Cho, Chang-Sang;Kim, Seungjin;Kang, Seongmin;Yoon, Hyeongi;Jeon, Eui-Chan
    • Journal of Climate Change Research
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    • v.6 no.3
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    • pp.175-184
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    • 2015
  • In this study GC and PAS were used to calculate $N_2O$ concentration of exhaust gas from Wood Chip combustion system. Fuel supplied to the incinerator was collected and analyzed and then the analysis result was used to calculate $N_2O$ emissions. Tier 3 and Tier 4 Method were used to calculate the $N_2O$ emissions. Plant's Specific emission factor of $N_2O$ by Tier 3 Method was 0.35 kg/TJ, while default emission factor of Wood?Wood Waste proposed by 2006 IPCC G/L was 4 kg/TJ. So the $N_2O$ emission factor of this study was 3.65 kg/TJ lower compared to the IPCC G/L. The total emissions calculated by Plant's specific emission factor was 4.22 kg during the measuring period, but by Tier 4 Method it was 7.88 kg. This difference in emissions was caused by the difference of continuous measuring and intermittent sampling. It would be necessary to apply continuous measuring to calculate emissions of $Non-CO_2$ gas whose the density distribution is relatively high. However currently, according to the target management guideline of greenhouse gas and energy, the continuous measuring method to calculate greenhouse gas emission is applied only to $CO_2$. Therefore for reliable greenhouse gas emission calculation it would be necessary to apply continuous measuring to calculate $Non-CO_2$ gas emission.

A Study on the Quantitative and Evaluation Weights of National Greenhouse Gas Emission Factors in the Mineral Industry (광물산업의 국가온실가스배출계수 정량·평가항목 가중치에 관한 연구)

  • Yoon, Yoongjoong;Cho, Changsang;Jeon, Eui Chan
    • Journal of Climate Change Research
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    • v.9 no.1
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    • pp.81-90
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    • 2018
  • "The Framework Act on Low-Carbon Green Growth" specifies the requirements for the development and verification of emission factors for establishing reliable national greenhouse gas statistics. The scope of the regulations covers the development and validation of energy, industrial processes, solvents and other product use, agriculture, land use, land use change and emission and absorption coefficients of the forestry and waste sector as defined in the 1996 IPCC Guideline and GPG 2000, The minerals sector to be covered in this study belongs to industrial processes. As a representative method for quantifying and evaluating GHG emission factors, there are emission grade quality grading and DARS (Data Rating Rating System) in the 'Procedures for Preparing Emission Factor Documents (1997)' reported by US-EPA. However, the above two methods are not specific and comprehensive, and lack the details for accurate emission factor verification. Therefore, there is a need for a method for verifying and quantifying certified greenhouse gas emission factors that reflects characteristics of each industry sector in Korea and accord with IPCC G/L and GHG target management. In this study, we conducted a weighted study on quantitative and evaluation lists of emission factor using questionnaires to develop a more accurate methodology for quantifying national greenhouse gas emission factors in the mineral sector. Quantification and evaluation of emission factor are classified into essential verification and quality evaluation. The essential verifications are : administrative compatibility, method of determining emission factors, emission characteristics, sampling methods and analysis methods, representativeness of data. The quality evaluations consisted of the quality control of the data, the accuracy of the measurement and analysis, the level of uncertainty, not directly affect the emission factor, but consisted of factors that determine data quality.

Domestic Bituminous Coal's Calorific Value Trend Analysis (2010~2014) and Carbon Emission Factor Development (국내 유연탄의 발열량 추이 분석(2010~2014년) 및 탄소배출계수 개발)

  • Kim, Min wook;Cho, Changsang;Jeon, Youngjae;Yang, Jinhyuk;Sin, Hochul;Jeon, Eui Chan
    • Journal of Climate Change Research
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    • v.7 no.4
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    • pp.513-520
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    • 2016
  • Korea's energy consumption has been constantly increasing. Final energy consumption was increased by an annual average of 2.9% compared to 2010. The consumption of all energy sources except for its oil was increased during the same time. While electric demand has increased coal consumption increased rapidly. Therefore, calorfic value and carbon emission factor development can improve the quality of Korea's greenhouse gas inventory. Calorific value is the amount of heat generated while burning coal. Caloric value is one of the most important factors in the development of carbon emission factors. Calorific value is used as the basis for the analysis of the various energy statistics. This study has calculated the other bituminous coal and coking coal's calorfic value by the data received from domestic coal-fired power plants and steel manufacturer. Calorofic value's trend analysis period is the year of 2010~2014. Through analyzing the carbon content it was calculated the carbon emission factor. The bituminous coal and coking coal's uncertainty analysis was performed using a Monte Carlo simulation.

Temporal Variability of CH4 Gas Concentration Collected in Sampling Bag (온실가스 시료 보관시간에 따른 CH4 농도 변화)

  • Hong, Yoonjung;Cho, Changsang;Kang, Seongmin;Yun, Hyun-Ki;Jeon, Eui-Chan
    • Journal of Climate Change Research
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    • v.7 no.4
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    • pp.477-484
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    • 2016
  • In general, $CH_4$ concentrations generated in combustion facilities are known to be ppm units. In most cases, $CH_4$ samples are collected in Tedlar bags and transported to laboratories for analysis. Considering this fact, in the present study, an attempt was made to find out how long samples can be stored in cases where they are kept in bags and transported as a preliminary study for sampling. According to the results of the experiment using simulated gases (1 ppm, 5 ppm, 10 ppm) in Tedlar bag, $CH_4$ was safe up to 240 hr which is the full time. In the case of simulated gases are containing 4 kind gases ($N_2$, $CO_2$, $CH_4$, and $N_2O$). Field samples (samples of obtained by collecting combustion facilities' exhaust gases) are known to contain highly reactive substances (for example NOx, SOx, and VOCs) and may affect each other. In the present study, one site sample was secured from each of a bituminous coal combustion facility and an LNG combustion facility and whether the concentrations of $CH_4$ gas would change over time (24 hr, 96 hr, 144 hr, 192 hr) was checked. Since site samples could not be analyzed on the day of collection, an experiment was started 24 hr after the time point of sampling to analyze the samples. As with the results of analysis of the simulated gas (240 hr), the results of analysis using the site sample indicated that it could be stored for the full study period 192 hr. Therefore, it was judged that if 192 hr would be taken after sampling before the sample would be analyzed, the concentration value should be reliable.

Temporal Variability of N2O Gas Concentration Collected in Tedlar Bag (테들러백에서 N2O농도의 시간적 변동성 연구)

  • Hong, Yoonjung;Kang, Seongmin;Cho, Changsang;Yun, Hyun-Ki;Jeon, Eui Chan
    • Journal of Climate Change Research
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    • v.9 no.1
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    • pp.59-67
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    • 2018
  • In this study, the $N_2O$, emitted from combustion facility, were analyzed by using simulated gas and field samples to find out how long samples can be stored in Tedlar bag. According to the results of the experiment using simulated gases (1 ppm, 5 ppm, 10 ppm) in Tedlar bag, After 144hr, $N_2O$ concentration of simulated gases changed that 1 ppm is 5.3%, 5 ppm is 12.8%, and 10ppm is 10.5%. The higher initial concentration of simulated gas was, the larger rate of $N_2O$ concentration was changed. In case of high concentration samples, it need to be careful when it was analyzed after 144 hr. Stability evaluation in Tedlar bag was carried out through field samples such as combustion facility of bituminous coal, B-C oil and LNG. The concentration rate of field samples, which is under 1 ppm of average initial concentration, was evaluated using statistical method. As a result, $N_2O$ concentrations were changed to field samples in the bag even when 96 hr had passed. And after sampling, it is necessary that sample analysis should be quickly as soon as possible.

Sub-bituminous Coal's Calorific Value Trend Analysis and Carbon Emission Factor Development (국내 아역청탄의 발열량 추이 분석과 탄소배출계수 개발)

  • Kim, Min wook;Cho, Changsang;Jeon, Youngjae;Yang, Jinhyuk;Sin, Hochul;Jeon, Eui Chan
    • Journal of Climate Change Research
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    • v.8 no.2
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    • pp.145-151
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    • 2017
  • Korea's energy consumption has been constantly increasing. Final energy consumption was increased by anannual average of 2.9% compared to 2010. The consumption of all energy sources except for its oil was increased during the same time. While electric demand has increased coal consumption increased rapidly. Therefore, calorfic value and carbon emission factor development can improve the quality of Korea's greenhouse gas inventory. Calorific value is the amount of heat generated while burning coal. Caloric value is one of the most important factors in the development of carbon emission factors. Calorific value is used as the basis for the analysis of the various energy statistics. This study has calculated the sub-bituminous coal's calorfic value by the data received from domestic coal-fired power plants. Calorofic value's trend analysis period is the year of 2011~2015. Through analyzing the carbon content it was calculated the carbon emission factor. The sub-bituminous coal's uncertainty analysis was performed using a Monte Carlo simulation.