• Title/Summary/Keyword: 질환 심각도

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TONGUE INJURIES BY SELF MUTILATION IN LESCH-NYHAN SYNDROME PATIENT: A CASE REPORT (Lesch-Nyhan 증후군 환아의 자해에 의한 혀의 외상)

  • Kim, Ji-Hee;Choi, Byung-Jai;Kim, Seong-Oh;Choi, Hyung-Jun;Son, Heung-Kyu;Lee, Jae-Ho
    • Journal of the korean academy of Pediatric Dentistry
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    • v.35 no.3
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    • pp.532-538
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    • 2008
  • Lesch-Nyhan syndrome is a rare X-linked recessively inherited disorder, caused by complete absence or decrease in activity of hypoxanthine guanine phosphoribosyl transferase(HPRT), an enzyme involved in purine metabolism. This enzyme deficiency gives rise to nephropathy symptoms, such as hyperuricosuria and hyperuricemia by excessive uric acid production and neuropathy symptoms, such as mental retardation, choreoathetosis and self mutilation behavior. Patients with Lesch-Nyhan syndrome have tendency to bite their lip, tongue and finger. In severe cases, partial or even total amputation of tongue or finger occur. Self-inflicted bites are often complicated by secondary infection to the injured site as well as pain. Furthermore tissue loss by biting results in esthetic problems. The dental management of self mutilation includes treatment with appliances such as soft mouth guard or lip bumper, extraction of all the teeth, and orthognathic surgery. We report a case of a 13 year-old boy with Lesch-Nyhan syndrome, who severely injured himself on his tongue. At first, conservative treatment using soft mouth guard was considered, but it could not prevent trauma on his tongue. Therefore, extraction of the lower anterior and posterior teeth was carried out.

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The Perception of Mental Health Status, Mental Health Literacy, Mental Health Welfare Center and Mental Health Business of among Local Students (일 지역사회 학생의 정신건강상태, 정신건강지식, 정신건강복지센터와 정신건강사업에 대한 인식조사)

  • Oh, Mi-Jung;Kim, Min-Ja;Chang, Koung-Oh
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.3
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    • pp.427-437
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    • 2020
  • This study investigated perceptions of mental health literacy, mental health status, mental health welfare center, and mental health business of local students. Totally, 388 students visiting the mental health welfare center located in G city were enrolled for the study. Data were collected from October 1 to October 26, 2018 using structured questionnaires, and analyzed by applying the IBM SPSS 24.0 statistics program. The mental health status of subjects was found to be most severely stressed (31.4%). The mental health literacy score of the subjects was 40.99 points, and 45.9% of the respondents had never heard of mental health welfare center. Considering mental health business, 68.3% had never heard of mental health counseling, and the most common way to access information about mental health or mental illness was the internet (58.0%). In addition, 75.3% respondents answered that an increase in the government budget for management of mental health and illness was required. Taken together, our results indicate the necessity to strengthen continuous education, promotion for mental health improvement, and the development of a customized mental health promotion program suitable for the student's level, through involvement of the community mental health welfare center.

외상 후 스트레스 장애의 평가

  • Kim Jeong-Beom
    • 대한불안의학회:학술대회논문집
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    • 2004.06a
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    • pp.185-213
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    • 2004
  • 우리는 살아가면서 흔히 개인적으로 극심한 스트레스를 겪거나 불행히도 어떤 뜻밖의 재난이나 큰 사고를 경험할 수 있다. 이런 외상적 사건들을 겪고 대부분의 사람들은 잘 극복할 수 있으나 일부 사람들은 심각한 의상 후 스트레스 반응을 보여 그런 외상이 지나감에도 불구하고 괴로운 기억 속에서 그것을 회상시키는 활동과 상황을 피하며 늘 불안한 마음으로 몸은 현재에 살고 있지만 마음은 실상 과거에 매달려 있고 과거의 고통 속에서 헤어 나오지 못하고 있다. 외상 후 스트레스 장애는 다른 불안 장애, 우울증처럼 흔한 질환으로 사회생활에 큰 지장을 주며 삶의 질을 손상시킨다. 그렇지만 외상을 당한 당사자들이 이런 이야기를 하기 꺼려하고, 이런 사람들을 진료실에서 종종 만날 수 있는 임상가들도 외상의 심각성과 외상 후 스트레스 장애에 대한 인식이 부족하여, 우리 주위에 많은 사람이 외상 후 스트레스 장애로 고생하고 있지만 외상 후 스트레스 장애로 진단되는 경우가 실제보다 훨씬 적다. 따라서 외상 후 스트레스 장애에 대한 평가를 배움으로써 더 많은 환자들을 정확히 진단하며 다른 질환과의 감별을 쉽게 할 수 있고, 환자들의 고통과 어려움이 과연 무엇인지 잘 알 수 있으며, 치료 표적과 치료 전략을 정하고, 치료 계획을 세우는 데 도움을 얻을 수 있다. 평가 방법으로는 구조화된 면담, 평가 척도, 정신 생리적 측정법, 치료자의 임상적인 결정 등이 있다. 향후에는 외상 후 스트레스 장애의 증상 정도뿐만 아니라 일상생활, 사회적 관계, 직업적, 사회적 적응 및 기능에 미치는 영향도 같이 평가하는 도구들이 개발되고, 현재 개발된 많은 평가 척도들이 새로이 수정되고 표준화되어, 이런 평가 척도들을 통해 외상 후 스트레스 장애의 경과와 외상 후 스트레스 장애로 인한 정신 사회적 영향을 더 잘 알 수 있는 자료들이 많이 수집되길 바란다. 대칭이, 작은대칭이, 펄조개는 저질이 니질인 곳에서 주로 서식하고 있었고 귀이빨대칭이는 사니질과 사질에 주로 서식하고 있었다. 특히 삽교호 수계 채집된 귀이빨대칭이는 사니질과 사질의 저질에서 출현하였다.및 내장낭 조직들이 중요한 에너지 저장소이며, 영양 공급 기관임을 알 수 있었으며, 폐각근 조직과 내장낭 조직들의 영양물질 함량 변화는 생식소의 에너지 요구에 따라 변하고 있음을 알 수 있었다.. 따른 신장 기능에 대한 영향을 평가해 보아야 한다.하를 조사한 결과, 연간 진동해역으로 유입되는 오염부하량은 부유물질 기준으로 전체 37,316 ton/yr로 추정되었고, 이중 육지기원 부하량이 9,809 ton/yr (26.3%) 였고, 해역의 침강량 23,576 ton/yr (63.2%), 양식생물의 배설량이 3,932 ton/yr (10.5%) 로 대부분이 해역의 침강량에 의한 것으로 조사되었다. 육지오염부하량이 변동이 없다는 전제 조건 아래, 진동만의 피조개 채묘장을 미더덕 양식장으로 품종전환시킬 경우, 전체 부하량은 산술적으로 약 196%가 증가한 72,998 ton/yr 가 되고, 양식생물의 배설량은 10배 정도 증가하게 되어 진동만의 오염부하를 가중하게 된다. 진동만은 여름철 빈산소수괴 및 적조가 빈번하게 발생하고 있으므로 미더덕 양식장을 새로이 시설할 경우 오염부하가 가중될 것으로 판단되어, 앞으로 진동만의 양식장 수용능력을 파악하여 적정량의 양식물량이 시설되어야 할 것이다.25 psu에서 가장 높게 나타났다.인 단백뇨는 진행성 경과의 위험성을 동시에 암시해 주는 매우 유용한 지표이다. 본 연구 결과 학교 신체 검사상에서 발견된 단독 단백뇨의 주된 원인은 기립성 단백뇨로 81.8%를 차지하였다. 그러나 지속성 단백뇨의 경우 비록 9.1%의 빈도를 보였지만, 신장 조직검사를 시행한 결과 진행성 경과를 취할 수 있는

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Clinical Evaluation of Surgical Treatment for Hemoptysis Patients (객혈환자의 외과적 처치에 대한 임상적평가)

  • 이성주;문승철
    • Journal of Chest Surgery
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    • v.30 no.11
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    • pp.1097-1104
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    • 1997
  • The expectoration of blood is always a fearful experience for the patient and a matter of grave concern to the attending physician, because it may be the warning sign of serious diseases. When such bleeding occurs, the possibility of its being due to pulmonary tuberculosis, bronchiectasis or carcinoma of the lung is promptly suggested. Nowadays, with the advance of modern diagnostic studies, differential diagnosis has become possible for the hemoptysis patients to have appropriate treatment. This evaluation is based on the review of 75 cases of patients whom we performed emergency open thoracotomies for 6 years from March 1992 to February 1997 in the Department of Thoracic and Cardiovascular Surgery, Seoul Adventist Hospital. The mean age of the patients was 36.6 years old with a range from 19 to 68, and most prevalent age group was thirties. The most common underlying lung disease causin hemoptysis was tuberculosis(44%). Most accurate diagnostic study was bronchoscopy during hemoptysis(95 Vo) and right middle & lower lobe(17.3%) was the most common site of lesion. Lobectomy(50%) was the most frequent operative method and recurrent hemoptysis(31.6%) was the most common postoperative complication. But most of the patients(82.6%) were completely recovered by surgical treatment. Now we concluded that the proper management of hemoptysis was completed by surgical approach with definite diagnosis and supportive medication.

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Acrodysostosis Associated with Symptomatic Cervical Spine Stenosis

  • Ko, Jung-Min;Kwack, Kyu-Sung;Kim, Sang-Hyun;Kim, Hyon-Ju
    • Journal of Genetic Medicine
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    • v.7 no.2
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    • pp.145-150
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    • 2010
  • Acrodysostosis is an extremely rare disorder characterized by short fingers and toes with peripheral dysostosis, nasal hypoplasia, and mental retardation. We report a 16-year-old Korean boy with acrodysostosis who had characteristic clinical features and cervical spine stenosis manifested by neurologic symptoms. On presentation, he complained of difficulty in raising his arms, and suffered from intermittent pain and weakness in both upper extremities. He had short stature and dysmorphic facial features, including a broad, depressed nasal bridge, small, upturned nose, bilateral epicanthal folds, and mild hypertelorism. Moderate mental retardation and sensorineural hearing loss in both ears were also present. Radiological findings included broad, short metacarpals and phalanges with cone-shaped epiphyses, bilateral Madelung deformities, hypertrophied first metatarsals, and thickening of the calvarium. Magnetic resonance imaging findings included stenosis of the cervical spine, platybasia with compression into the cervicomedullary junction, and downward displacement of the cerebellar tonsils. Here, we report a case of acrodysostosis with symptoms and signs of cervical spinal stenosis first in Korea. If it is diagnosed in the early stages, possible life-threatening complications, including spinal canal stenosis, can be managed properly and permanent neurologic sequelae might be avoided. Therefore, it is important to consider acrodysostosis in the differential diagnosis of peripheral dysostosis.

The Perception of Mental Health Literacy, Mental Health Status, Mental Health Welfare Center and Mental Health Business and of among Local Public Officials (일 지역사회 일반직 공무원의 정신건강지식, 정신건강상태, 정신건강복지센터 및 정신건강사업에 대한 인식조사)

  • Kim, Min-Ja;Chang, Koung-Oh;Lee, Seung-Ae
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.12
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    • pp.639-650
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    • 2020
  • The purpose of this study was to investigate perceptions of mental health literacy, mental health status, mental health welfare center and mental health business of local public officials. The participants were 762 public officials working in G city. Data were collected from October 1, to October 26, 2019 using structured questionnaires, and IBM SPSS 24.0 statistics program was used for the analysis. As a result, the mental health status of the subjects was the most severe stress 28.1%. The mental health literacy score of the subjects was 40.99 points and mental health status was 1.66 points. And 46.6% of the respondents had never heard of mental health welfare center. As for mental health business, 57.0% had never heard of mental health counseling, and the most common route for gaining information on mental health or mental illness was TV at 65.2%. In addition, 85.0% answered that an increase in the government budget for the management of mental health and illness was necessary. Therefore, it is necessary to strengthen the continuous education and promotion for mental health improvement and the development of customized mental health promotion programs suitable for the public officials level through of the community mental health welfare center.

Recent Studies on Natural Products that Improve Browning (Browning 촉진에 관여하는 최근 천연물의 동향)

  • Lee, Eunbi;Nam, Ju-Ock
    • Journal of Life Science
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    • v.31 no.11
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    • pp.1037-1045
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    • 2021
  • The prevalence of obesity is increasing worldwide, and since obesity is associated with dietary factors and sedentary lifestyles, it is a disease that is readily developing in the modern population. Because obesity is accompanied by serious complications such as diabetes and cardiovascular disease, prevention and treatment are important. Currently, drugs such as liraglutide and phentermine are used to treat obesity by suppressing appetite and inducing gastrointestinal motility delay. However, various side effects may occur, including thyroid cancer, cardiovascular problems, and central nervous system disorders. Therefore, to explore an obesity treatment method with relatively few side effects, a method known as "fat browning" was introduced to change white adipose tissue into brown adipose tissue to increase energy consumption. Ongoing studies are attempting to find effective natural substances to safely induce browning. Many natural substances have been identified. The induction of browning by treatment with natural substances generally involves three mechanisms: positive control of browning-inducing factors, inhibition of differentiation into white adipose tissue, and the activation of mechanisms related to browning. In this study, we describe plant extracts with known browning-inducing effects, such as strawberry, black raspberry, cinnamomum cassia, and Ecklonia stolonifera extracts. We also summarize the underlying mechanisms of action identified thus far, including the signaling pathway mediated by these extracts to induce browning. Furthermore, the effects of brown adipose tissue generated through browning on heart disease as an endocrine organ disruptor are discussed.

A Study on Effects of the Fall Prevention in the Rehabilitation Pilates Exercise (노인의 재활 필라테스 운동이 낙상 예방 효과에 대한 고찰)

  • Ji-Sun Kim
    • Journal of the Korean Applied Science and Technology
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    • v.40 no.2
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    • pp.290-300
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    • 2023
  • This study was understood the risk mechanism of falls in the elderly and reviewed previous research data to see if the principle of Pilates rehabilitation exercise could have a positive effect on balance ability and postural stabilization in the elderly, and the purpose of this study is to present literature-based data on the fall prevention effect of rehabilitation Pilates exercise. First, the rehabilitation Pilates exercise makes it available for strengthening the center of the body to stabilize the spine and pelvis and stimulates the nerve root, thereby having an effect on the balance and the joint stabilization. Second, a proprioceptive sensory impairment and a musculoskeletal degenerative disease due to aging increase the loss of balance ability and the instability in posture maintenance, thereby coming to raise the risk of a fall damage caused by the difficulty in performing motor functions and by the gait disturbance. Third, the rehabilitation Pilates exercise leads to improving the core muscle strength in older adults, resulting in being capable of expecting the betterment in the balance and the reaction time motor function. And there is a positive impact on the improvement in body imbalance and on the stability in movement involved in the fall prevention, resulting in being able to suggest the possibility of likely contributing to a reduction in a fall risk rate. In conclusion, the rehabilitation Pilates as the elderly exercise program showed effects on the improvement in the body's muscular strength, on the upgrade in a sense of balance, and on the stabilization of core. Thus, it was considered to diminish the risk factors for a fall damage caused by musculoskeletal degeneration and to be capable of preventing a serious disorder of activity due to a chronic senile disease.

Factors affecting the ability of older adults to identify symptoms of depression (노인의 우울증상 식별력에 영향을 미치는 요인)

  • Lee, Sun Hae;Ko, Jung Eun
    • 한국노년학
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    • v.29 no.2
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    • pp.529-546
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    • 2009
  • Depression in old age not only is prevalent but also causes a considerable amount of burden in physical, psychosocial, and economic terms. Intervention, however, is often delayed due to the understanding that considers depressive symptoms as a normal process of aging or signs of physical illnesses. Since the recognition of symptoms often initiate one's help seeking process, a correct identification of symptoms can contribute to early detection and intervention to depression in oneself as well as in others. This study interviewed 104 older adults living in an urban area, and explored their ability to correctly identify depressive symptoms and factors related to identification. The study results show that respondents who were able to correctly identify symptoms of depression were only 14%, and the rest defined the symptoms as social, economic, and other psychological issues. Of the factors in the logistic regression model, age being 75 and over and mass media as source of mental health information affected negatively their ability to correctly identify symptoms; mental health education programs affected positively their ability. Based on these results, it is suggested that such strategies as employing a face-to-face provision of concrete information and counseling can be more effective than delivering information via large-scale lectures. Additionally, a future research deems necessary to conduct an in-depth examination of mental health/illness-related contents on mass media.

A Study on the Implementation of Urban Senior Multi-Carezon for the Elderly (고령화에 따른 도시형 노인 시니어 멀티 케어존 실효성에 관한연구)

  • Lee, Jong-Sik
    • Journal of the Korea Knowledge Information Technology Society
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    • v.13 no.2
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    • pp.273-286
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    • 2018
  • Korean government has taken various population policy so far According to demographic results, The aging population is rapidly aging and it is expected to deepen in the future. However, many senior citizens are also exposed to poor economic conditions and inconsistent health care risks Most seniors suffer from mental illness and chronic diseases. seniors in traditional cities feel very alienated as they change from large family to small family. As the number of elderly people living alone grows, social problems increase. At present, the health care for the elderly who live alone is not being taken properly, and they are under a very poor management system, both physically and mentally. Every human being has to be old, and we aim to spend our old age processes physically and mentally healthy. As the basic age of the elderly increases, it is necessary to consider various aspects of the welfare policies and medical policies that are followed. In this study, 100 elderly people over the age of 65 were surveyed for economic situations and physical and mental health conditions, and specially performed study on utility of 'urban senior multi care zone' to prove the necessity of introducing the latest digital devices to resolve these problems more effectively by analyzing serious feelings of alienation, loneliness, and emotional situations. Lastly, We conducted this research to find ways to help the elderly through customized health care.