• Journal of Sasang Constitutional Medicine
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• v.11 no.1
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• pp.281-293
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• 1999

1. The backdrop of the study. Accurate diagnasis of the constitution is very important Sasang constitution medicine. This study make research of man's penis and woman's breast, make observation these are significant or not in diagnosis of the constitution. 2. The process. The constitution of the people was diagnosed by QSCCII, specialist, (86 persons, men 39, women 47), the men was taken measure of atony and excited length, thickness of the penis with a rule, thread. the women have a personal interview about her height, weight, the girth of the breast, brassiere cup size. 3.The result. This study shows that Tae-eum-in Is 28 persons(32.6%), So-eum-in 37 persons (43%), So-yang-in 21 persons(24.4%). Man's observation is insignificant statistically, woman's observation is insignificant statistically too.

• Korean Journal of Microbiology
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• v.51 no.4
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• pp.419-426
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• 2015

The aims of this study were to isolate spore-forming Bacillus strains that exhibit high digestibility and anti-pathogenic bacteria toward feed for calves. Total 136 spore-forming strains were isolated from finished feeds and their ingredients. Among them, 93 strains were identified as Bacillus species when analyzed by 16S rRNA sequencing. For industrial use, three strains named as Bacillus licheniformis SHS14, B. subtilis LCB7, B. amyloliquefaciens LCB10 were selected after evaluating the industrial standards that are related with heat and acid resistance, enzyme activities, and anti-pathogenic activities against Samonella dublin ATCC15480 and E. coli K99. After each culture, 3 selected strains were mixed together at 1:1:1 (v/v/v) ratio and then prepared as the mixed starter culture for feeding. The changes in microbial community were analyzed via 16S rRNA metagenomics. The initial community ratio among three strains was maintained even after manufacturing into final products. Also, in vitro, enzymatic and anti-pathogenic activities were almost same as those when cultured in single culture, and results of anti-pathogenic activities conducted with calves showed 90% activities against lincomycin, which would be indicative of a promising feed starter.

• Journal of fish pathology
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• v.5 no.2
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• pp.159-164
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• 1992

The skin of fishes is also the important external barrier against a variety of the environmental detrimental agents, allowing normal internal physiological function, so its condition is very important in many disease processes. Since fishes are aquatic, morphologically and physiologically they posses specific characteristics lacking in terrestial animals. Thus, it is necessary to keep in mind various specific histologic characteristics for a precise interpretation of the histopathological lesions. In the normal environment the fish skin is more subtly adapted for its physiological requirements as a limiting barrier than the skin of higher terrestial vertebrates. However, its delicacy makes it high vulnerable to damage in fish culture facilities or polluted waters. Although changes in the skin of fish such as discoloration, ulcerative lesions, are the the most readily observed clinical features of fish, there is a wide variety of possible responses, which are best considered in terms of their site within the skin. Up to now, there are relatively few sytematically described information on the histological structure of the teleost skin as well as integrated reviews of the range of pathological processes that can occur in teleost skin. Therefore it was tried in this article to rearrange the information already described by other investigators on the histological structure and histopathological changes of teleost skin.

• Journal of fish pathology
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• v.24 no.2
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• pp.85-93
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• 2011

Edwardsiella tarda is a broadly infectious agent against freshwater and seawater fishes. In the present study, E. tarda specific phage was isolated from fish farms on the west coast of Korea, and the effect of environmental factors such as pH and water temperature on the phage activity was investigated. As a fish model, Nile tilapia (Oreochromis niloticus) was used and the interaction between E. tarda and phage was investigated. The phage activity, in pH test, appeared even higher in seawater than freshwater and was evenly constant up to $50^{\circ}C$. The phage and E. tarda were inoculated in tilapia and the phage activity and E. tarda viability were checked on the time intervals. As a result, the number of E. tarda in the group of E. tarda plus phage was constantly reduced to 24 hr post-inoculation compared to the control group without phage, whereas the phage activity was slightly increased in the experiment group. The results suggest that it might be possible to use phage to control the fish disease caused by E. tarda.

• Journal of the Korean Society of Food Science and Nutrition
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• v.25 no.6
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• pp.1055-1061
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• 1996

This study was conducted to assess meal management and nutrient intake of 357 elderlies in Ulsan. 114 male and 243 female elderlies over 65 year old were recruited from July 5 to August 13, 1995. Questionnaires for general characteristics of the subjects(such as family size, living cost, pocket money and health condition) and for meal management were used. The levels of depression and anxiety were measured by CED-S and Spielbuger's STAI-S, respectively In addition, nutrient intakes were conducted by convenience methods. Nutrient intake of male and female showed the average daily intake of energy, Protein, vitamin A, vitamin $B_2, $ and vitamin C were lower than Korean recommended dietary allowances(RDA). But other nutrient intake were higher than RDA except that calcium intake of female was lower. Most nutrient intakes were positively correlated with family size, living cost, pocket money and health condition. Depression and anxiety scores were also negatively correlated with most of nutrient intakes. The pattern of meal management could predict nutrient intakes as expected : regularity and pleansantness of eating were positively correlated with nutrient intakes, whereas unbalanced meal and eating lonely were negatively correlated with them.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.27 no.1
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• pp.133-150
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• 2001

자유라디칼은 반응성이 커서 세포의 구성 물질인 단백질, 지질, 당, DNA등과 반응하여 세포 및 조직을 손상시킴으로서 노화를 가져온다. 이러한 자유라디칼들은 자외선, 일반 대사, 스트레스, 질병, 흡연 등에 의해 생성되고 특히, 활성 산소 종인 hydroxyl radical, superoxide radical, lipid peroxide radical등은 피부 노화를 발생시키는 원인이 된다. 따라서 본 연구에서는 한방 식물로부터 유해한 활성 산소종을 소거하는 활성을 가진 물질을 기 위해 1차 스크리닝 하였고, 이중 육두구, 관중, 초두구, 빈랑, 금은화, 포공영, 우롱차, 황금, 녹차 추출물이 효과가 높게 나타났으며, 그중 초두구와 빈랑 90% 메탄올 추출물에서 가장 우수한 소거 활성을 나타냄으로써 이 추출물에 대하여 자유라디칼 소거 활성에 대하여 여러 가지 생물학적 활성을 조사하였다. 초두구와 빈랑추출물에 대한 hydroxyl radical, superoxide radical, lipid peroxide radical을 소거하는 활성을 핵산, 클로로포름, 에틸아세테이트, 물층으로 분획하여 조사한 결과 에틸아세테이트층에서 가장 우수한 활성을 보였다. 에틸아세테이트 분획에 대한 lipid peroxide radical 소거에 있어서 빈랑 추출물이 $IC_{50}$/ 값 50 $\mu\textrm{g}$/ml, 초두구 추출물은 $IC_{50}$/ 값 59 $\mu\textrm{g}$/ml로서 기준물질로 사용되는 vitamic C (120 $\mu\textrm{g}$/ml)나 butylated hydroxyl toluene (80 $\mu\textrm{g}$/ml) 보다 더 우수한 소거 효과를 보여주었고, hydroxyl radical을 소거하는 능력은 25 $\mu\textrm{g}$/ml와 150 $\mu\textrm{g}$/ml로 hydroxyl radical의 소거 능이 좋은 vitamin C (180 $\mu\textrm{g}$/ml) 보다 뛰어난 소거 활성을 나타내었다. Superoxide radical을 소거하는 효과는 초두구 추출물의 $IC_{50}$/ 값 10 $\mu\textrm{g}$/ml, 빈랑 추출물이 15 $\mu\textrm{g}$/ml을 나타냈고, 이는 기준 물질인 vitamin C (35 $\mu\textrm{g}$/ml)보다 좋은 소거 활성을 보여주었으며, gallic acid 9 $\mu\textrm{g}$/ml과 유사한 효과를 나타내었다. 사람 섬유아세포를 배양하여 hydroxyl radical과 superoxide radical를 발생시킨 후 초두구와 빈랑 추출물의 세포 보호 효과를 실험한 결과 25 $\mu\textrm{g}$/ml의 농도로 처리하였을 때 각각 85% 이상의 우수한 세포 보호 효과를 나타내었다. 초두구로부터는 자유라디칼 소거 활성이 있는 물질을 분리하기 위하여 분획한 후 가장 높은 소거 활성을 보인 에틸아세테이트 층에 대하여 silica column chromatography, preparative TLC를 수행하였다. 초두구로부터 분리된 물질은 HPLC를 이용한 분리에서 phenol성 물질인 gallic acid와 동일한 retention time을 보여줌으로써 초두구로부터 분리된 물질은 gallic acid와 유사한 phenol성 물질이거나 그의 유도체일 것으로 추측된다. 따라서, 초두구와 빈랑 추출물은 피부 노화의 주요인이 되고 있는 lipid radical, hydroxyl radical, superoxide radical을 소거하는 활성이 뛰어나 자유라디칼에 의하여 발생되는 피부노화를 방지할수 있는 물질로서의 효과가 기대된다.가 기대된다.

• Journal of Hospice and Palliative Care
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• v.20 no.2
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• pp.81-92
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• 2017

Chronic obstructive pulmonary disease (COPD) is characterized by persistent airflow limitation that is usually progressive. It is a major cause of morbidity and mortality worldwide, leading to substantial and increasing economic and social burden. Palliative care for COPD patients aims to reduce symptoms and exacerbations and improve exercise tolerance and quality of life. It is difficult to make a prognosis for COPD patients due to the variable illness trajectory and advanced care of patients. However, severity of breathlessness, assessment of lung function impairment, and frequency of exacerbations can help to identify palliative care needs and determine effective methods to mitigate symptoms, which is discussed in this paper. In these patients, it is recommended to provide individualized palliative care along with curative/restorative care at the onset of COPD symptoms. Before launching a palliative care system in Korea, it is necessary to prepare pulmonary rehabilitation resources, patient-centered communication, timely palliative responsiveness, and a program for effective advanced care planning. A multidisciplinary approach involving collaboration with not only the respiratory and palliative care teams but also primary care offers a new model of care for these patients and should be considered with a priority.

• Korean Journal of Social Welfare
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• v.57 no.2
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• pp.41-70
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• 2005

The object of the study is to examine the change of social-economic structure and poverty-shape to escape poverty. In Korea, the working poor have been increased by flexibility and division of labor market since the economic crisis in 1997, and are faced with hard conditions due to the vulnerable welfare system. Especially the workers who engage in irregular jobs were increased by restructure of labor market. Besides they are in unstable employment terms such as low payment, low-skill and exclusion from welfare-benefit. Many small independent businessmen are also in danger of poverty for enterprises trend to move abroad by globalization. Poverty policy in our country was focused on the absolute poor class that has relation with old age, unemployment, disable, disease etc, so they were the object of welfare policy. The poverties, however, are increasing rapidly after the economic crisis, and they work so hard but are still poor, that is, participation in labor market doesn't become an element to escape poverty. Thus the emergence of new poverties whose core consists of the working poor becomes to need new poverty policy. The study is to survey change of their economic conditions, their welfare conditions, their experiences and responses of social dangers after the economic crisis, then to explore the policy to escape poverty. As the result of the study, it shows that the working poor experienced many kinds of social dangers like unemployment, decrease of income etc. In their welfare conditions as their responses to the social dangers, the benefit of social insurance, enterprise welfare like legal retirement pay and paid leave and private welfare such as private pension and insurance are low. The working poor are faced with social dangers, moreover, they don't have skill or education for adapting themselves to information society. The study says that it needs variable policies for the working poor to escape poverty, and suggests payment & tax policies as stable income policy, occupational discipline and skill-education for promoting the quality of employment, moreover, social insurance as expansion of social welfare policy and housing & education policies whose objects are the working poor.

• Tuberculosis and Respiratory Diseases
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• v.40 no.5
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• pp.595-601
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• 1993

Background: Today, tuberculosis continues as an important cause of death in Korea despite the effective treatment and prevention. So we have studied charicteristic distribution of death by pulmonary tuberculosis through epidemiologic survey. Subjects and Method: The mortality data were obtained from 684 pulmonary tuberculosis cases who died in a tuberculosis-centered hospital in Seoul during the period of 5 years from 1986 to 1990. In order to estimate the distribution of death by tuberculosis, t-test and $x^2$-text were performed on the data. Results: 1) 19.9% of patients died among the total 3,441 hospitalized pulmonary tuberculosis cases during 5 years. 2) In distribution of sex and age, male death occupies 81% of total death. Significantly high proportions of younger female death (under 40 years-old) were also observed. 3) In terms of medical security status, medical assistance group occupies 42.3% of medical insurance group while the non-security group also occupies 11.8% of total death. 4) Treatment interruption was observed in 78% of total death. Conclusion: Special attention should be given to the identification, management and follow up of high risk group in nationwide tuberculosis control program.

• Journal of the Korean Data and Information Science Society
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• v.28 no.6
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• pp.1337-1348
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• 2017

In this paper, we develop the high-risk drinking predictive model in Korea using the cross-sectional data from Korea Community Health Survey (2014). We perform the logistic regression analysis, the decision tree analysis, and the neural network analysis using the data mining technique. The results of logistic regression analysis showed that men in their forties had a high risk and the risk of office workers and sales workers were high. Especially, current smokers had higher risk of high-risk drinking. Neural network analysis and logistic regression were the most significant in terms of AUROC (area under a receiver operation characteristic curve) among the three models. The high-risk drinking predictive model developed in this study and the selection method of the high-risk intensive drinking group can be the basis for providing more effective health care services such as hazardous drinking prevention education, and improvement of drinking program.