• Title/Summary/Keyword: 질량 추정

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Hydrogen Peroxide Modulates Phospholipase $A_2$ Aactivity and Endogenous Oxidative Stress in the Free Radical Induced Acute Lung Injury (과산화수소에 의한 급성폐손상시 염증성 지질분자의 생성기전에 관한 연구)

  • Bae, Chi-Hoon;Kang, Hyung-Seok;Lee, Sub;Jheon, Sang-Hoon;Ahn, Wook-Wu;Kwon, Oh-Choon
    • Journal of Chest Surgery
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    • v.35 no.5
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    • pp.343-349
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    • 2002
  • background: In an attempt to investigate the role of oxidants in the activation of phospholipase $A_2$(PLA$_2$) and endogenous oxidative stress in the lung. acute inflammatory lung injury was induced by the instillation of hydrogen peroxide into the trachea of Sprague-Dawley rats. Material and Method: To prove the hypothesis thats released oxidants from neutrophils activate the PLA$_2$ retrogradely, activities of PLA$_2$ and lysoplatelet activating factor acetyltransferase(lysoPAF AT) were assayed i hours after instillation of hydrogen peroxide. In addition, to confirm the impairing effects of the activation of PLA$_2$ associated with endogenous oxidative stress, lung weight/body weight ratio(L$\times$10$^{-3}$ B), protein contents(mg/two lungs) in bronchoalveolar lavage(BAL) were measured. As neutrophilic respiratory burst has been known to play a pivotal role in the genesis of endogenous oxidative stress associated with acute inflammatory lung injury, BAL neutrophils counts and level of lung myelperoxidase(MPO) were measured after hydorgen peroxide insult. Morphological and histochemical studies were also performed to identify the effect of the endogenous oxidative stress. Result: Five hours after hydrogen peroxide instillation, lungs showed marked infiltration of neutrophils and increased weight. Protein contents in BAL increased significantly compared to those of normal rats. PLA$_2$ activity was enhanced in the hydrogen peroxide instilled group. Interestingly, the accelerated production of platelet activating factor(PAF) was confirmed by the increased activity of lysoPAF AT in the $H_2O$$_2$ employed lung. Morphologically, light microscopic findings of lungs after instillation of hydrogen peroxide showed atelectasis and infiltration of inflammatory cells, which was thought to be caused by lipid mediators produced by PLA$_2$ activation. In cerium chloride cytochemical electron microscopy, dense deposits of cerrous perhydroxide were identified. In contrast, no deposit of cerrous perhydroxide was found in the normal lung.

Principle and Recent Advances of Neuroactivation Study (신경 활성화 연구의 원리와 최근 동향)

  • Kang, Eun-Joo
    • Nuclear Medicine and Molecular Imaging
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    • v.41 no.2
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    • pp.172-180
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    • 2007
  • Among the nuclear medicine imaging methods available today, $H_2^{15}O-PET$ is most widely used by cognitive neuroscientists to examine regional brain function via the measurement of regional cerebral blood flow (rCBF). The short half-life of the radioactively labeled probe, $^{15}O$, often allows repeated measures from the same subjects in many different task conditions. $H_2^{15}O-$ PET, however, has technical limitations relative to other methods of functional neuroimaging, e.g., fMRI, including relatively poor time and spatial resolutions, and, frequently, insufficient statistical power for analysis of individual subjects. However, recent technical developments, such as the 3-D acquisition method provide relatively good image quality with a smaller radioactive dosage, which in turn results in more PET scans from each individual, thus providing sufficient statistical power for the analysis of individual subject's data. Furthermore, the noise free scanner environment $H_2^{15}O$ PET, along with discrete acquisition of data for each task condition, are important advantages of PET over other functional imaging methods regarding studying state-dependent changes in brain activity. This review presents both the limitations and advantages of $^{15}O-PET$, and outlines the design of efficient PET protocols, using examples of recent PET studies both in the normal healthy population, and in the clinical population.

Estimation of Potential Evapotranspiration using LAI (LAI를 고려한 잠재증발산량 추정)

  • Kim, Joo-Hun;Kim, Kyung-Tak
    • Journal of the Korean Association of Geographic Information Studies
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    • v.8 no.4
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    • pp.1-13
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    • 2005
  • In the process of a hydrology circulation, evapotranspiration is considered a very important factor to build a plan for the development of water resources and to operate water resources system. This study purposes to estimate daily potential evapotranspiration quantity in consideration of energy factors of the surface by using spatial information such as Landsat TM (ETM+) data, DEM and Landcover. Kyounan-cheon, Han River is selected as a target area, and landcover is divided by vegetation and non-vegetation covered area. Penman-Monteith equation which considers leaf-area index is used to estimate potential evapotranspiration quantity of vegetation covered area. The combination method (energy burget and aerodynamic method) is used in non-vegetation covered area. Among the input data for estimating potential evapotranspiration, NDVI, SR and Albedo is formed by Landsat, TM and ETM+ from 1986 through 2002. ground heat flux is estimated by using NDVI distribution map, LAI distribution map is drawn by using SR distribution map. The result of estimation shows that the average potential evapotranspiration in the whole basin is about 1.8-3.2mm/day per each cell. THe results of estimating potential evapotranspiration quantity by each landcover are as follows; water surface 3.6-4.9mm/day, city 1.4-3.1mm/day, bareland 1.4-3.5mm/day, grassland 1.7-3.7mm/day, forest 1.7-3.0mm/day and farmland 1.8-3.6mm/day. The potential evapotranspiration quantity is underestimated in comparison with observed evaporation data by evaporation pan, but it is considered that it has physical propriety.

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Implementation of Intelligent Image Surveillance System based Context (컨텍스트 기반의 지능형 영상 감시 시스템 구현에 관한 연구)

  • Moon, Sung-Ryong;Shin, Seong
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.47 no.3
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    • pp.11-22
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    • 2010
  • This paper is a study on implementation of intelligent image surveillance system using context information and supplements temporal-spatial constraint, the weak point in which it is hard to process it in real time. In this paper, we propose scene analysis algorithm which can be processed in real time in various environments at low resolution video(320*240) comprised of 30 frames per second. The proposed algorithm gets rid of background and meaningless frame among continuous frames. And, this paper uses wavelet transform and edge histogram to detect shot boundary. Next, representative key-frame in shot boundary is selected by key-frame selection parameter and edge histogram, mathematical morphology are used to detect only motion region. We define each four basic contexts in accordance with angles of feature points by applying vertical and horizontal ratio for the motion region of detected object. These are standing, laying, seating and walking. Finally, we carry out scene analysis by defining simple context model composed with general context and emergency context through estimating each context's connection status and configure a system in order to check real time processing possibility. The proposed system shows the performance of 92.5% in terms of recognition rate for a video of low resolution and processing speed is 0.74 second in average per frame, so that we can check real time processing is possible.

Thermal CVD of Silica Thin Film by Organic Silane Compound (유기 실란화합물을 이용한 SiO2 박막의 열CVD)

  • Kim, Byung-Hoon;Ahn, Ho-Geun;Imaishi, Nobuyuki
    • Applied Chemistry for Engineering
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    • v.10 no.7
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    • pp.985-989
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    • 1999
  • Silica($SiO_2$) thin film was synthesized by a low pressure metal organic chemical vapor deposition(LPMOCVD) using organic silane compound. Triethyl orthosilicate was used as a source material. Operation pressure was 1~100 torr at outlet of the reactor and deposition temperature was $600{\sim}900^{\circ}C$. The experimental results showed that the high reaction temperature and high source gas concentration led to higher growth rate of $SiO_2$. The step coverage of films on micro-scale trenches was fairly good, which resulted from the phenomena that the condensed oligomers flow into the trenches. We estimated a reaction path that the source gas polymerizes and produces oligomers (dimer, trimer, tetramer, etc.), which diffuse and condense on the solid surface. The chemical species in the gas phase at the outlet of reactor tube were analyzed by quadrapole mass spectrometer. The peaks, assigned to be monomer, dimer of source gas and geavier molecules, were observed at 650 or $700^{\circ}C$. At higher temperature($900^{\circ}C$), the peaks of the heavy molecules disappeared, because almost all the source gas and intermediate(polymerized oligomer) molecules were oxidized or condensed on colder tube wall.

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Material Characteristics of White Wares from Yeongdong Province, Gangwon-do: Gangneung and Donghae Kiln Sites (강원 영동지역 백자의 재료과학적 특성 연구: 강릉 남양리 백자가마터와 동해 발한동2(사문동) 가마터를 중심으로)

  • Lee, Byeong Hoon;So, Myoung-Gi
    • Journal of Conservation Science
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    • v.31 no.3
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    • pp.181-192
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    • 2015
  • This study aims to examine production technique of twelve white wares from the Gangneung Namyang-ri and Donghae Balhan-dong2(Samun-dong) kiln sites, Kangwon Province and characteristics of the used materials, and to find a correlation among materials of the excavated white wares. X-ray fluorescence sequential spectroscopy(XRF), X-ray diffraction(XRD), Dilatometer and Inductively coupled plasma mass spectrometry(ICP-MS), Inductively coupled plasma automic emission spectrometer(ICP-AES) were applied to determine the chemical composition, crystalline phase of samples, firing temperatures, trace elements and rare earth elements. When analyzing body crystalline phases of the white wares using the XRD method, quartz and mullite were extracted from all the samples. Though firing temperature of each sample was different, they were mostly fired at a temperature below $1200^{\circ}C$. Analyzing the excavated white wares using the Seger formula, compositional properties of white wares in Gangneung Namyang-ri kiln showed diffrently from the Donghae Balhan-dong2(Samun-dong) kiln. The body of white wares from Gangneung Namyang-ri kiln have higher raito of $RO_2$ and $RO+R_2O$ than of white wares from Donghae Balhan-dong2(Samun-dong) kiln site. The white wares from Gangneung Namyang-ri kiln and Donghae Balhan-dong2(Samun-dong) kiln were made of host rocks of the different geological origin, according to the result of rare earth elements analysis.

The Effect of Radiation Therapy on the Healing Ability of Subsequent Surgical Wounds (방사선조사가 피부의 창상치유에 미치는 실험적 연구)

  • Suh, Hyun-Suk;Rhee, Chung-Sik
    • Radiation Oncology Journal
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    • v.9 no.1
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    • pp.17-25
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    • 1991
  • This study was undertaken to find the effect of radiation therapy on the healing ability of surgical wounds and on this basis, to find the proper time interval between the radiation therapy and surgery. Two hundred and fifty-two mice were used and a single dose of 2000 cGy was given in each instances to the hind limb of mice. Incisional wounds were produced after varying intervals in the previously irradiated areas and then they were followed up at regular intervals by the measurement of tensile strength. The wounds which received surgery immediately, 1 or 2 weeks after irradiation revealed marked delay and the wounds which received surgery 12, 16 or 20 weeks after irradiation demonstrated slight delay in wound healing in terms of tensile strength measurement. But the wounds which received irradiation 4 or 8 weeks before surgery did not differ much in the wound healing process from that of the control group. Histopathologic studies of the wounds demonstrated epithelization in most instances as quickly as in the control wounds. The appearance of fibroblasts and collagen fibers has delayed momently and appeared to have close correlation with the tensile strength healing curves.

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IUE SPECTRA OF SEYEERT 1 GALAXY NGC 7469-BLR CHARACTERISTICS OF NGC 7469 (SEYFERT 1 은하 NGC 7469의 IUE SPECTRA-NGC 7469 BLR의 물리적 특성)

  • Son, Dong-Hoon;Hyung, Siek
    • Journal of Astronomy and Space Sciences
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    • v.22 no.3
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    • pp.187-196
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    • 2005
  • From the line ratios of Si III] 1892 to C III] 1909 (Feibelman & Aller 1987), we estimated the BLR electron densities and their changes of Seyfert 1 galaxy NGC 7469 using IUE spectra observed from June 11 to July 29, 1996 (Wanders et al. 1997). We separated blended Si III] and C III] lines using the STARLINK/DIPSO and measured their fluxes within the error of $12.4\%\;and\;6.6\%,$ respectively. Electron density fluctuated from $10^{9.69}\;to\;10^{10.93}$ during about two month period, i.e. 17.3 times density variation within 50 days. We also derived time delays from UV emission line variations .elative to the continuum $(at\;1315{\AA}):$ 2 days for C IV, 4 days for C III], 8 days for Si III]. This suggests that their stratified UV line emission regions are at 0.002 pc, 0.004 pc and 0.006 pc, respectively, from the central region. Based on the BLR sizes and their rotation velocities deduced from the line profiles, we estimate the central black hole mass as about $10^6M_{\odot}$

Reference Spent Nuclear Fuel for Pyroprocessing Facility Design (파이로공정 시설 개념설계를 위한 기준 사용후핵연료 선정)

  • Cho, Dong-Keun;Yoon, Seok-Kyun;Choi, Heui-Joo;Choi, Jong-Won;Ko, Won-Il
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.6 no.3
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    • pp.225-232
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    • 2008
  • An estimation has been made for inventories and characteristics of spent nuclear fuel(SNF) to be generated from existing and planned nuclear power plants based on the 3rd Basic Plan for Electric Power Demand and Supply. The characteristics under consideration in this study are dimensions, a fuel rod array, a weight, $^{235}U$ enrichment, and the discharge burnup in terms of fuel assembly. These are essentially needed for designing a pyroprocessing facility. It is appeared that the anticipated quantity by the end of 2077 is about 23,000 tU for PWR spent nuclear fuel. It is revealed that the proportion of SNF with the initial $^{235}U$ enrichment below 4.5 weight percent(wt.%) is approximately 95 % in total. For SNF with 16$\times$16 fuel rod array the proportion is expected approximately 74% in total. It appears that the average burnup of SNF will be 55 GWd/tU after the medium and/or latter part of 2010s while the average burnup is 45 GWd/tU at present. Finally, a requirement in terms of reference SNF for designing the pyroprocessing facility has been derived from the above-mentioned results. The anticipated SNF seems to be 16$\times$16 Korean Standard Fuel Assembly with a cross section of 21.4 cm$\times$21.4 cm, a length of 453 cm, a mass of 672 kg, the initial $^{235}U$ enrichment of 4.5 wt.%, and the discharge burnup of 55 GWd/tU.

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Age Constraints on Human Footmarks in Hamori Formation, Jeiu Island, Korea (제주도 하모리층에 발달하는 사람 발자국의 형성시기)

  • Cho Deung-Lyong;Park Ki-Hwa;Jin Jae-Hwa;Hong Wan
    • The Journal of the Petrological Society of Korea
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    • v.14 no.3 s.41
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    • pp.149-156
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    • 2005
  • Ar-Ar, carbon AMS and OSL dating was carried out to clarify the age of the human footmarks on the Hamori Formation, Jeju Island, Korea. $^{40}Ar/^{39}Ar$ ages of trachybasalt from the Songaksan Tuff, which is underlain by the Hamori Formation, range between $10.6{\pm}19.9\;Ka$ and $11.7{\pm}26.3\;Ka$. Radiocarbon AMS ages of humin fractions extracted from sediment samples yielded the maximum limit age of the Hamori Formation as $15,161{\pm}70\;yr$ B.P. The OSL dating of the top and bottom layers of the Hamori Formation gave $6.8{\pm}0.3\;ka$ and $7.6{\pm}0.5\;ka$, respectively, suggesting that timing of the human footmarks formation can be constrained as between ca 6,800 yr B.P. and 7,600 yr B.P.