• Journal of the Korea Convergence Society
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• v.9 no.3
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• pp.101-109
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• 2018

The purpose of this study was to investigate the relation between health behaviors and asthma among male and female adolescents. The data were derived from the 12th Korea youth risk behavior web-based survey 2016 in Korea. The subjects were 65,528 Korean adolescents. The diagnosis rate of asthma in male adolescents was 10.3% and the diagnosis rate of asthma in female adolescents was 7.8%. In male adolescent, health behaviors that related to diagnosis of asthma were drinking (OR=1.087), second-hand smoke exposure (OR=1.087), non-vigorous physical activity (OR=1.084), obesity (OR=1.291), insufficient sleep time (OR=1.113), and stress (OR=1.257). In female adolescents, health behaviors related to asthma were smoking (OR=1.242), second-hand smoke exposure (OR=1.111), vigorous physical activity (OR=0.899), obesity (OR=1.178), and stress (OR=1.251). The results of this study will be used as basic data to develop a health promotion program of asthma youth according to gender.

• The Journal of the Convergence on Culture Technology
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• v.10 no.1
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• pp.105-110
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• 2024

Among those who participated in the 8th 1st year of the National Health and Nutrition Examination Survey (2019), diabetes patients were divided into 4 types and the prevalence and diagnosis rates of diabetes were investigated by age group. In addition, we analyzed the correlation between glycated hemoglobin levels and body weight, waist circumference, cholesterol, triglyceride levels, weight-adjusted waist circumference, and body mass index in patients already diagnosed with diabetes. As a result of the study, the prevalence of diabetes in 2019 was 16.03%, and male The prevalence rate for men continued to increase after the 30s, and that for women was lower than that for men until the 40s, but increased rapidly after the 50s and became similar to that of men after the 70s. In the diabetes diagnosis group, the glycated hemoglobin level had a low and non-significant correlation with weight, waist circumference, BMI, and WWI levels, but showed a correlation coefficient of 0.178 with the triglyceride level, and the p value was less than 0.001, which was statistically very significant.

• Proceedings of the KSAR Conference
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• 2001.03a
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• pp.65-65
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• 2001

본 연구는 칡소 귀세포를 공여핵으로 이용한 체세포 복제송아지 생산에 있어서 배양방법이 배발생 및 배반포 발달율에 미치는 영향과 체세포 복제란의 이식후 수태율에 미치는 영향을조사하여 복제송아지의 생산 효율을 제고하고자 실시하였다. 실험에 공시된 공여핵은 칡소 의 귀세포를 회수하여 10%FBS가 첨가된 DMEM배지에서 3-4일 동안 배양하여 monolayar Confluent 형성 후 0.25% trypsin을 처리하여 준비하였으며 공여세포는 적어도 passage가 5회 이상의 세포만을 사용하였다. 복제수정란의 생산은 18-20시간 동안 체외성숙 된 난자의 핵을 제거하고 공여핵을 주입하여 2.2kv/cm, 10$\mu\textrm{s}$의 전압으로 2회 자극함으로 융합하였으며, 융합된 난자는 5$\mu\textrm{g}$/$m\ell$ ionomycin에서 4분간, 1.9mM 6-dimethyl aminopurine에서 4시간동안 배양하여 활성화처리를 하였다. 핵이식수정란의 배양은 39$^{\circ}C$, 5%$CO_2$ incubator에서 처리구 I은 CRlaa에서 4일간 배양 후 CR2aa배지에서 배양, 처리구II는 CRlaa에 4일간 배양후 CR2aa배지에 cumulus cell과 공배양, 처리구III은 CR2aa 배지에 camulus cell과 함께 배양하였다. 수정란이식은 발정발현 7일째에 비외과적 방법으로 젖소 미경산우에 이식하였으며 이식란수는 2~4개의 핵이식된 수정란을 이식하였다. 임신진단은 45~60일 사이에 직장검사 및 초음파 진단기를 이용하여 실시하였다. 배양방법에 따른 배발생율은 처리구 I에서 92.2 %(83/90)으로 처리구II와 III의 62.4%(63/101)와 77.8%(144/185)에 비하여 높게 나타났으나 배반포 발달율은 처리구II와III에서 65.1%(41/63)와 50.0%(72/144)로 처리구 I의 30.1%(25/83)보다 높게 나타났다. 각 처리구에 따른 수정란 이식후 수태율은 처리구II와 III에서 공히 20%의 수태율을 나타낸 반면 처리구 I에서는 수태가 되지 않았다. 따라서 체세포 복제수정란의 생산에 있어서 배반포 발달율과 수태율을 높이기 위해서는 단순배양보다 공배양이 더 효과적인 것으로 사료되지만 이런 결과가 복제송아지 생산효율에 있어서도 효과적일지는 향후 더 많은 연구가 있어야 할 것으로 사료된다.

• Progress in Medical Physics
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• v.21 no.1
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• pp.22-28
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• 2010

To evaluate the potential value of $^1H$ Magnetic resonance spectroscopy (MRS) for detecting and characterizing invasive ductal carcinoma of breast. We conducted $^1H$ Magnetic resonance spectroscopy (MRS), using a 3.0T MR scanner, on 40 patients who were histologically diagnosed to have invasive ductal carcinoma (IDC); tumor areas of the patients were designated as experimental samples, and non-tumor areas as control samples. The peak at 3.2 ppm is characteristically intense and observed in 34 cases of the total 40 invasive ductal carcinoma (sensitivity 86.2%; specificity 100%; positive predictive value 100%; negative predictive value 60%). In constrast peak at 1.3 ppm is characteristically intense and observed in normal breast (sensitivity 86.2%; specificity 100%; positive predictive value 100%; negative predictive value 60%). The study shows that $^1H$ MRS can effectively discriminate invasive ductal carcinoma from normal breast in most cases. It also demonstrates the feasibility of localized in vivo $^1H$ MRS technique as a new diagnostic modality in the detection of breast tumor.

• Tuberculosis and Respiratory Diseases
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• v.44 no.2
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• pp.391-400
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• 1997

Background : Bronchoscopy is an essential procedure for identifying the bleeding site and evaluating cause of hemoptysis. However, it is controversial regarding to the timing of bronchoscopy in patients with hemoptysis. Early bronchoscopy, which was performed during hemoptysis or with 48hour after cessation of bleeding, was better for identifying the site of bleeding compared with delayed bronchoscopy, which was performed 48 hours after cessation of bleeding. The diagnostic yield of identifying the bleeding site by bronchoscopy was variable in reported literature and the safety of early bronchoscopy was not mentioned in previous literature. Therefore, we evaluated the efficacy and safety of early bronchoscopy in patients with hemoptysis. Method : From October 1994 to August 1996 in Samsung Medical Center, bronchoscopy was performed in patients with hemoptysis. Early bronchoscopy was performed prospectively during hemoptysis or within 48 hours after cessation of bleeding from May 1995 to August 1996. Delayed bronchoscopy group included patients who did not received early bronchoscopy at the same period or in whom bronchoscopy was performed 48 hour after cessation of bleeding from October 1994 to May 1995. Results : Early bronchoscopy group was performed 73 times in 71 patients. Delayed bronchoscopy was performed in 57 times in 55 patients. There was no difference as to amount and underlying cause of hemoptysis between both groups. Indentification of bleeding site by visualizing active bleeding was significantly higher in early bronchoscopy (38.3%) than delayed bronchoscopy group (8.7%)(p < 0.05). Indentification of bleeding site by bleeding after clot removal was 8 in early and 10 in delayed bronchoscopy. Indentification of bleeding site by visualizing active bleeding and bleeding after clot removal was 36 in early and 15 patients in delayed bronchoscopy(p > 0.05). Causes of hemoptysis was found in 18 patients in early and 16 patients in delayed bronchoscopy group. patients who had early bronchoscopy underwent surgery. We diagnosed the site of bleeding in 4 patients preoperatively. In 3 patients we made a treatment plan promptly right after bronchoscopy. Among early bronchoscopy group, bleeding over 100cc during bronchoscopy occurred in 2 patients. In early bronchoscopy group there was no other major complication during bronchoscopy. Conclusion : In patients with hemoptysis, early bronchoscopy which performed within 48 hours after cessation of bleeding was more effective procedure for identifying the bleeding site than delayed bronchoscopy which was performed after 48 hour cessation of bleeding.

• 건강소식
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• v.36 no.2
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• pp.24-25
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• 2012

우리나라의 암 발생률 1위인 위암 유병률이 0.4%인 반면 갑상선암의 유병률은 1% 정도로 높게 나타나고 있다. 최근 건강검진사업이 활성화 되면서 초음파를 통한 갑상선결절 진단율이 28.7%까지 보고되는 것을 보면 10명 중에 2~3명은 갑상선에 이상이 있음을 알 수 있다. 갑상선암은 20세 이하, 60세 이상에서는 드문 암으로 되어 있으며, 최근 전 국민 건강검진실시와 더불어 중년의 여성에서 진단되는 경우가 매우 증가하는 추세다. 목에 뭔가 만져지면서 이유 없이 붓거나, 이물감으로 음식물을 삼키기 어려울 때, 목소리가 이상할 때는 갑상선 전문의와의 상담이 중요하다.

• Proceedings of the KIEE Conference
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• 2007.07a
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• pp.758-759
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• 2007

본 논문은 변압기 이상진단을 위한 유중가스분석법의 진단신뢰도 향상을 위해 기존의 추출율이 높은 토플러 추출방법에 대한 결과와 Headspace 분석법에 의한 결과를 각각 비교하고, Headspace 추출법에 의한 결과의 정확도 향상을 위해 여러가지 인자들을 고려하였다. 향후 최적 조건을 수립하여 수은에 의한 인체 유해성이 없는 Headspace 분석법으로의 전환을 모색하고자 한다.

• Journal of the korean veterinary medical association
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• v.30 no.3
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• pp.145-148
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• 1994

광견병은 모든 온혈동물의 급성전염병으로 일부 선진국가를 제외한 세계 각국에서 발생되고 있는 인수공통전염병이다. 병원체는 신경친화성을 가진 광견병바이러스(rabies virus)로써 전파는 주로 감염 동물의 교상에 의하며 드물게는 감염동물이 분비하는 배설물에 의해 공기전염도 가능하다. 일단 사람이 동물로 부터 감염되었을 때 즉시 치료하지 않으면 사망율이 높은 질병이다. 따라서 조기 진단과 예방이 무엇보다도 중요하므로 이 글에서는 국내 수의분야에서 실시하고 있는 진단방법과 예방약의 개발현황 등을 소개하고자 한다.

• Journal of Veterinary Clinics
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• v.19 no.3
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• pp.295-298
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• 2002

This study was conducted to develope noninvasive fecal PCR assay for detecting the Helicobacter species in dogs. From the DNA isolated from fecal samples, and a region of the 16S rRNA gene conserved among Helicobacter spp. was amplified In comparison with gastric biopsy test, the fecal PCR assay showed high specificity(100%) and sensitivity(96%). The prevalence of Helicobacter spp. infection in privately owned pet dogs in Korea detemined by the fecal PCR assay was 72.1%. the fecal PCR assay determined in this study can a new noninvasive test detecting Helicobacter spp. infection in dogs.

• The Journal of Korean Medicine
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• v.17 no.2 s.32
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• pp.337-393
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• 1996

The purpose of this study is to evaluate and standardize the four scales of Questionnaire for the Sasang Constitution Classification 　II (QSCCII). QSCCII is newly prepared by statistical item analysis and is designed to examine its diagnostic discriminability. QSCCII is administered to 1366 random informants. From the survey, we could get the data for the standardization. The criteria of standardization are based on the data from 265 informants who are examined by professionals. Collectted data are analyzed by internal consistency, variation analysis(ANOVA), Duncan test and discrimination analysis of SPSS PC+ V4.0 program. The results are as follows reliability of four scales for QSCCII is relatively valid. The internal consistency of Tae-yang(太陽) (太陽) scale is Cronbach's a=0.5708. That of So-yang(少陽) scale is a=0.5708. That of Tae-eum(太陰) scale is a =0.5922. That of So-eum(少陰) scale is a=0.6319. 2. There is a significant difference between each group through variation analysis of four scales. 3. The process of standardization is based on the average value and standard deviation with respect to age and sex difference of each criteria 4. This study suggests a source of standardization of Sasang Constitution Classification by providing norms in which the differences of age, sex, and number of items are taken into deep consideration. QSCC Ⅱ, therefore, can be applied to every age(the 10's to the 60's) and sex groups. 5. The recalculation of the raw-score to standard value (T-score) shows that the diagnostic discriminability (Hit-ratio: 70.08%) of QSCC Ⅱ brings about 37% improvement than proportional chance criteria (33.33%). Especially, Hit-ratios of Tae-eum In(74.5%) and So-eum In(70.8%) are higher than that of So-yang In(60.0%). 6. QSCC has discriminability only to male informants. Compared with QSCC, however, QSCC II has relatively efficient discriminability both to male and female informants. 7. These results would be a demonstration of the fact that the QSCC II could be used as a tool for sasang constitution classification.