• Journal of the korean academy of Pediatric Dentistry
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• v.43 no.4
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• pp.452-460
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• 2016

Burkitt lymphoma (BL) is an aggressive form of non-Hodgkin's B-cell lymphoma found primarily in the pediatric population. In the oral cavity, this tumor can grow rapidly and often brings about facial swelling or development of an exophytic mass involving the jaws. A 5-year-old boy was referred for swelling and pain in the left mandibular area. The patient showed diffuse swelling on the left side of the mandible and firm-moderate tenderness upon palpation. An intraoral examination showed moderate mobility and sensitivity to percussion on the left primary first and second molars, without severe caries. A radiographic examination revealed complete loss of the lamina dura on the left primary second molar and permanent first molar. There was a radiolucent osteolytic lesion and destruction of the cortical bone of the left mandibular body. Based on the clinical, radiographic, and immunohistochemical findings, the patient was diagnosed with BL, and was referred to a pediatrician for systemic evaluation and intensive chemotherapy. Even before the completion of chemotherapy, the swelling resolved and the displaced teeth were relocated to a normal position. This patient showed a good prognosis due to prompt diagnosis and intensive chemotherapy. Early diagnosis and referral for treatment can prevent the development of BL.

• Tuberculosis and Respiratory Diseases
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• v.63 no.4
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• pp.387-391
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• 2007

Fibrosing mediastinitis is a rare disease that is characterized by the proliferation of dense fibrous tissue of the mediastinum. The pathogenesis of fibrosing mediastinitis is unknown in most cases. However, histoplasmosis, tuberculosis, autoimmune disease, radiation therapy, and other idiopathic fibroinflammatory diseases have been implicated in some cases. Most clinical features are related to an obstruction or compression of the mediastinal structure. Fibrosing mediastinitis is often progressive and occurs diffusely throughout the mediastinum. We encountered a case of fibrosing mediastinitis of a very focal lesion without evidence of mediastinal involvement. The condition was confirmed by biopsy and graft bypass surgery was performed because of SVC syndrome.

• Journal of the Korean Society of Safety
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• v.23 no.3
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• pp.79-86
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• 2008

In the manufacturing industries using HDI(hexamethylene diisocyanate) product hardeners, exposure to HDI is common to spray painters in terms of inhalation and dermal or ocular contact. Due to a lack of information for spray painters in automobile and furniture industries, a questionnaire survey was conducted for the prevalence of adverse health symptoms(33 spray painters and an unexposed group n = 91) to assess the importance of personal controls. Despite the small sample size, common health symptoms were reported, such as skin symptoms(dry cracked skin-61% and dermatitis/skin irritation-33%) and respiratory symptoms(phlegm-49%, asthma-21%). In addition, other adverse health symptoms were reported, such as skin rash(12%), cough(39%), shortness of breath with wheezing(30%), chest tightness and difficulty in breathing(30%). No significant eye symptoms were reported. It was founded that the adverse health symptoms reported in this study were related to poor personal work practices and inappropriate PPE use. Therefore, appropriate personal controls like PPE use, work practices, regular training and education are suggested to minimize the risk of health symptoms. In addition, medical examination will also be suggested for individual health effects.

• The Journal of Internal Korean Medicine
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• v.26 no.4
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• pp.785-794
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• 2005

Little is known concerning the pathophysiology and symptomatology of gastric dysmotility of patients who have sought treatment in eastern traditional medicine. The aim of this study was to investigate gastric electrical activity and clinical characteristics between gastroparesis and non-gastroparetic functional dyspepsia(FD) and assess the necessity to distinguish them for eastern traditional medical treatment. 60 patients were surveyed by questionnaire. Gastric electrical activity was recorded and analyzed using electrogas-trography. Patients were divided into gastroparesis and non-gastroparetic FD by 1.0 of power ratio. Healthy persons were used as reference. Postprandial normogastria of gastroparesis decreased and that of non-gastroparetic functional dyspepsia increased compared before and after meals. Suggested causes of onset were the meat diets that most patients were on in the gastroparesis group, and that drugs that patients in the non-gastroparetic FD group were taking. Distribution of main symptom was equally regular in patients with gastroparesis, but patients with non-gastroparetic FD showed mainly upper abdominal pain and fullness. Values for the gastroparesis group were double those for the non-gastroparesis FD group in frequency of upper GI endosopic examination. Results suggest that effective application of eastern traditional medical treatment requires that first a clear distinction be made in state of gastric dysmotility and clinical characteristics of gastroparesis and non-gastroparesis FD when treating dyspepsia.

• Korean Journal of Environmental Biology
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• v.18 no.1
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• pp.1-20
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• 2000

There are increasing evidences of climate change in the Antarctic and Arctic Oceans, especially elevated temperature due to the continuous burning of the fossil fuels and ultraviolet B(UV-B) flux within the ozone hole. Light-dependent, temperature-sensitive, and fast-growing organisms respond to these physical and biogeochemical changes. Polar marine phytoplankton, which are pioneer endemic species and important carbon contributors in the polar waters, are therefore highly suitable biological indicators of such changes. By virtue of light requirement, the primary producers are exposed to extreme seasonal fluctuations in temperature, photosynthetically active radiation, and UV radiation. Local environmental warming and increased UV-B radiation during ozone depletion may have profound effects on the primary producers that are primary carbon producers in the polar water. Small changes in climate temperature and solar radiation may have profound effects on the activity threshold of the polar phytoplanktion. To demonstrate biological response to the environmental changes, standardized representative natural and biological parameters are needed so that replicate samples (including controls) can be taken over extended periods of time. In this paper, we review general characteristics of polar phytoplankton, their environment, environmental changes in the polar waters, the effects on the environmental changes to the polar phytoplankton, and the importance of the polar phytoplankton to understand the global environmental changes. [Biological indicators, Global environmental change, Polar phytoplankton, UV].

• Research in Community and Public Health Nursing
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• v.7 no.2
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• pp.410-419
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• 1996

This study was reviewed from 1000 articles related to family planning from 1970 to 1990 and 20 articles associated with natural family planning from 1980 until the present. The purpose of natural family planning(NFP) is to identify the time ovulation of women themselves, to have intercourse with periodic abstinence, and to deliver a healthy child. The ultimate goal of NFP is to promote the family's health. The NFP method is described as periodic abstinence of intercourse to avoid pregnancy by identifying the ovulation time in the menstration cycle. Clinical symptoms and signs of reflection underlying changes in Estrogen and Progesterone are the change of basal body temperature, the change of cervical mucus and cervix, abdominal pain and breast tenderness. The types of NFP are the calender rthythm method, basal body temperature methods, cervical mucus method, symptothermal method, cyclo-thermal method and home based ovulation test kits. Recently the cyclo-thermal method involved. It is calendar rhythm method applied to B.B.T. For the cervical mucus method, when the estrogen level in the blood concentration is increased, the mucus begins to excrete, the amount of moist mucus increases while the mucus is clear, slippery, and smooth. For 3 days, this timing can be considered contraception. Fertility is at a maximum on the day mucus appears, abstinence for 3 days is a type of contraception. Sexual intercourse on a maximum day of mucus maximizes pregnancy potential. But, the contraception depends on the practice of a perfect rule. For basal body temperature methods, at ovulation time, the temperature increases $0.2^{\circ}C-0.5^{\circ}C$. Through the review of literature a high temperature above $0.2^{\circ}C$ for 3 days indicates that the previous 6 day period was ovulation and fertilization. The Symptothermal method is used to determine the prediction of ovulation through the observation of mucus excretion, high temperature, the change of cervical mucus, low abdominal pain, vaginal discharge, and breast change. Home based ovulation test kits are cervico-vaginal fluid aspiration, test a digital electric thermometer, body fluid(blood, saliva, urine) test kits, They are on the market. However, research on the contraception method is still in progress. For pregnancy it is still too early to use home based ovulation test kits because of deficit of reliability and simplicity more research on the technology is needed. It is suggested that NFP methods be included in nursing curriculum in order to educate NFP users how to effectively use NFP methods. Furthermore, this study has implications for the dissemination of NFP methods in terms of Korean policies of family planning and the support of community welfare agences.

• The Journal of Korean Medicine
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• v.26 no.2 s.62
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• pp.77-84
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• 2005

Objectives: Chunghyul-dan is a combinatorial herbal medicine, and previous studies reported it had therapeutic effects for microangiopathy, which is a major part. in the progression of stroke, as well as having anti-hypertensive, anti-hyperlipidemic, anti-apoptotic, anti-oxidative, and anti-inflammatory activities, Therefore, we examined the inhibitory effect of Chunghyul-dan on stroke occurrence in patients with silent brain infarction. Methods: We prescribed Chunghyul-dan at 600 mg a day to patients with silent brain infarction confirmed by brain MRI, and monitored stroke occurrence, drug compliances, and adverse effects for 1 year, We then performed follow-up brain MRI to detect new vascular lesions after 1 year of Chunghyul-dan medication. As for the subjects lost to follow-up, we assessed their prognosis after 1 year by telephone. Results: There were twenty-one subjects who were treated with Chunghyul-dan for more than 1 year, None of them experienced new clinical syndromes characterized by rapidly developing clinical symptoms and signs of focal and at times global loss of brain function, which could be accompanied with evidence of stroke occurrence, or any adverse effects during the Chunghyul-dan medication period. These results might be explained by various biochemical effects of Chunghyul-dan on microangiopathy, which is closely related with cell cycle progression, hypertension, hyperlipidemia, vascular inflammation, and oxidative damage. Of the 10 subjects lost to follow-up, six were reached; two of them had stroke occurrence. Conclusions: We suggest Chunghyul-dan could be useful for prevention of stroke occurrence in patients with silent brain infarction by preventing the progression of microangiopathy. Further study with a randomized controlled trial is needed to confirm this suggestion.

• The Journal of Pediatrics of Korean Medicine
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• v.31 no.4
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• pp.31-38
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• 2017

Objectives The purpose of this study was to find out the clinically reliable relationships between the Risser sign and chronological age, bone age, menarche, and adult height prediction (AHP) and to evidence the reliability of the Risser sign. Methods This study had been carried out with 50 children who had their growth checked in an oriental medical hospital from January 2015 to February 2017. We investigated Risser sign in AP X-rays with iliac crest, bone age, AHP for all 50 children and the timing of menarche from the 22 girls in the study subjects. We also investigated a correlation between the Risser stage and the other indicators to analyze statistical data. Results The mean chronological ages of Risser 1, 2, 3 and 4 were 11.2, 12.6, 14.4, and 15.5 years respectively for the boys and 10.8, 12.2, 13.8 and 14.8 years respectively for the girls. The mean bone ages of Risser 1, 2, 3 and 4 were 12.3, 13.6, 15.7 and 16.5 years respectively for the boys and 11.7, 13.8, 14.3 and 14.9 years respectively for the girls. We analyzed 22 girls' Risser stages in accordance with the duration from menarche. The result showed that in the first six months after menarche, all girls were in Risser 1 and 2; in the next six months, the girls were in Risser 2 on average; in the next 12 months, all girls were in Risser 3 and 4; after more than two years from menarche, all girls were in Risser 4. The mean remaining growth height of Risser 1, 2, 3 and 4 were 27.8, 17.3, 4.4 and 1.0 cm respectively for the boys and 14.5, 5.1, 3.1 and 1.1 cm respectively for the girls. The Risser stage was correlated strongly with chronological age (Spearman's rho=0.707 (boy), 0.841 (girl)), bone age (Spearman's rho=0.869 (boy), 0.875 (girl)), duration from menarche (Spearman's rho=0.909) and remaining growth height (Spearman's rho=-0.784 (boy), -0.878 (girl)). Conclusions This study showed that the Risser sign can be useful in assessing skeletal maturity and predicting remaining growth height based on the Risser stage and the other growth indicators.

• Journal of Korean Medical classics
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• v.18 no.4 s.31
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• pp.155-165
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• 2005

진당시기대상한론치법적연구유(晋唐時期對傷寒論治法的硏究有): 왕숙화운용당시성행적(王叔和運用當時盛行的)‘한(汗), 토(吐), 하(下), 온(溫), 구(灸), 자(刺), 수(水), 화(火)’등팔법(等八法), 귀납료상한론적증치경험(歸納了傷寒論的證治經驗); 손사막근거자기적임상경험(孫思邈根據自己的臨床經驗), 파상한론적태양병편진행료(把傷寒論的太陽病篇進行了)‘이방명법(以方名法), 안법류증(按法類證)’, 저시해시기대상한론육경병치법적대표성적연구(這是該時期對傷寒論六經病治法的代表性的硏究), 저종연구유원시화력사적국한성(這種硏究有原始和歷史的局限性), 종중국의학대상한론육경병치법적연구력사고려(從中國醫學對傷寒論六經病治法的硏究歷史考慮), 저성위료후세적치법연구적선구자(這成爲了後世的治法硏究的先驅者), 구유비상대적영향(具有非常大的影響). 재송대대상한론치법적연구상(在宋代對傷寒論治法的硏究上), 기관건작용적의가유방안시화주굉(起關鍵作用的醫家有龐安時和朱肱). 타문대상한론치료원칙적천발(他們對傷寒論治療原則的闡發), 대륙경병적분석귀납(對六經病的分析歸納), 이급제시구체적치법상(以及提示具體的治法上), 도주출료공헌(都做出了貢獻). 방안시주장료응안인(龐安時主張了應按人), 지(地), 시제정치료적사상(時制定治療的思想); 주굉이(朱肱以)‘병유표본(病有標本), 치유선후(治有先後)’위치료원칙(爲治療原則), 여상한론상결합진행치료(與傷寒論相結合進行治療), 대후세의가산생료영향(對後世醫家産生了影響). 도료금원대성무기(到了金元代成無己), 류완소(劉完素), 왕호고등(王好古等), 대내경내용각자이사상관점(對內經內容各自以思想觀点), 분별안변증론치총결료육경병적치료규율(分別按辨證論治總結了六經病的治療規律), 동시대증후화방약진행료분석(同時對證候和方藥進行了分析), 천명료구체적육경병치법적병리전귀(闡明了具體的六經病治法的病理轉歸), 도유기독창성(都有其獨創性). 성무기용내경해석료상한론(成無己用內經解釋了傷寒論), 총결해기(總結解肌) 발한(發汗) 중제발한(重劑發汗) 해표행수(解表行水) 화해(和解) 공비 지열(止熱) 삼설등치법, 위후세대상한론치법적연구개벽료도로, 인이갱가명확화해적개념(因而更加明確和解的槪念), 병응용지금(幷應用至今). 류완소제창료주화론(劉完素提倡了主火論), 중시료상한론한(重視了傷寒論汗), 토(吐), 하삼법적연구(下三法的硏究), 창립료신량해표법(創立了辛凉解表法), 대후세온병치료적발전대래료흔대영향. 왕호고작위이수학파(王好古作爲易水學派), 운용장부적한열허실이론결합약미효능(運用臟腑的寒熱虛實理論結合藥味效能), 탐색료상한론육경병적치료규율(探索了傷寒論六經病的治療規律), 강조료양명병적익진액적치료원칙(强調了陽明病的益津液的治療原則), 대후세연구상한론치법급여료흔대적계발. 이상대상한론치법연구(以上對傷寒論治法硏究), 불근성위당시임상의학적선도(不僅成爲當時臨床醫學的先導), 이차성위료후세연구상한론치법적기초(而且成爲了後世硏究傷寒論治法的基礎).

• Journal of Yeungnam Medical Science
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• v.10 no.1
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• pp.157-165
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• 1993

The authors conducted a clinical observation of 13 cases of pulmonary aspergilloma at Yeungnam University Hospital from March 1983 to March 1992, and the following results were observed : 1) The male to female ratio was 1 : 1.2, and the age distribution was ranged 30 to 67 years old. 2) All cases were symptomatic : hemoptysis, cough, sputum and dyspnea. Especially, hemoptysis was the presenting compliant in 10 patients(77%). 3) The underlying lung disease were pulmonary tuberculosis in 9, COPD in 5 and bronchiectasis in 2, 3 cases were without underlying disease. 4) According to radiographic appearance, 8 cases had the typical crescent sign and 5 cases were seen nodular lesion. And the lesions of 11 cases were located in both upper lung. 5) 10 cases were treated with surgical resection. Among these cases, 8 cases were alieved and 2 cases, died. And other 3 cases were treated with conservative treatment. We suggest that these findings would be helpful for the diagnosis and treatment of pulmonary aspergilloma and further study might be needed to evaluate the prognosis of pulmonary aspergilloma.