• Tuberculosis and Respiratory Diseases
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• v.48 no.5
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• pp.757-765
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• 2000

Background : Angiogenesis plays a critical role in human tumor growth and metastasis. Microvessel count as a measure of tumor angiogenesis, has been significantly correlated with invasive and metastatic patterns in breast. prostate and cutaneous carcinomas. Materials and Methods : Fifty patients with curatively resected non-small cell lung cancer were evaluated. Tumor tissues embedded in paraffin block were stained by anti CD 31 (PECAM, platelet endothelial cellular adhesion molecule) using immunohistochemical method to assess microvessel count. Microvessels were counted in the most active areas of neovascularization(microscopy, 200$\times$). Results: 1) Mean microvessel count was 47.1$\pm$17.7(per 200$\times$field) in total 50 cases. 2) Mean microvessel count of adenocarcinoma (54.4$\pm$19.9) was significantly higher than that of squamous cancer (43.9$\pm$16.2) (p<0.05), but there were no relationship between microvessel count and TNM stages. 3) Median survival time, 2-year and 5-year survival rates of the low microvascular group (microvessel count<45, 22 cases) were 61 months, 80% and 40%, respectively, and those of the high microvascular group(microvessel count$\geq$45, 28 cases) were 46 months, 75% and 12%, respectively. As results, prognosis of low microvascular group is statistically significantly superior to that of the high microvascular group (p=0.0162, Kaplan-Meier, log-rank). Conclusion : Angiogenesis assessed by microvessel count can be used as one of the significant prognostic factors in non-small cell lung cancer.

• Proceedings of the Korea Water Resources Association Conference
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• 2010.05a
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• pp.1031-1034
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• 2010

지난 2008년 11월 중앙정부와 팔당수계 7개 시 군은 수질보전과 더불어 지역사회의 개발을 위해 2008년 '수질오염총량관리제도'(이하 오총제)의 의무제 도입을 합의하였다. 오총제의 의무제 도입에 따라 수행되어야 할 각 유역별 토지이용 특성 분석 및 배출되는 오염물질의 정도의 명확한 규명이 이루어지지 않고 있기 때문에 유역관리의 방향 설정이 어려운 상황에 놓여있다. 이에 본 연구는 기존의 농도규제에서 좀 더 과학적 수질관리 기법인 총량관리 개념의 '수질오염 총량관리제도'의 도입에 따라 효율적이며 과학적인 소유역 관리를 위해, 토지이용과 오염물질 유출 간의 관계를 파악하고자 하였다. 대상유역은 앞서 언급한 7개 시 군의 각각 주요 하천 3개소를 선정하여 총 21개소를 2009년 6월부터 12월까지 7개월 동안 월 3회씩 BOD 및 COD를 모니터링하였다. 또한 그 유역을 전수조사를 통해 토지이용도를 조사하였다. 연구결과를 요약하면, 토지이용에 따른 산림지역이 가장 많은 지역은 가평군 남양주시로 나타났고, 도시 및 주거지가 많은 지역은 여주군, 용인시 및 이천시이며, 농지가 많은 지역은 양평군 여주군으로 나타났다. COD 및 BOD의 배출 정도는 농지와 도시 및 주거지가 많은 지역에서 높은 수준(p<$0.05^*$)으로 나타났으며, 특히 도시 및 주거지가 많은 유역에서 그 정도가 더욱 심각한 것으로 나타났다. 이에 반하여 임지의 토지 이용률이 증가할수록 BOD 및 COD 평균농도는 감소하는 것으로 나타났다(p<0.001).

• Journal of Oral Medicine and Pain
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• v.31 no.2
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• pp.113-120
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• 2006

The purpose of this study was to investigate whether there were any changes in taste sensitivity with oral lichen planus (OLP). Sixty subjects (26 males and 34 females) were included for the study and they were categorized into 2 groups (oral lichen planus 30 persons,control 30 persons), oral lichen planus group was investigated in the department of Oral Medicine, College of Dentistry, Pusan National University from April, 2005 to February, 2006 and control group was investigated in the clinic at Cheongju City from february, 2006 to april, 2006. The electrical taste thresholds were measured using an electrogustometer of the 4 different sites (tongue tip, tongue lateral, circumvallate papilla and soft palate) in oral cavity. The results were as follows; 1. The electrical taste threshold showed a tendency to decrease in the OLP group. 2. The electrical taste threshold showed a tendency to decrease in female group, but showed a tendency to increase in male group of the OLP group. 3. The electrical taste threshold showed a tendency to increase in tongue tip, tongue lateral of the multiple OLP group, but showed a tendency to decrease in circumvallate papilla, soft palate of the multiple OLP group. 4. The electrical taste threshold showed a tendency to increase in tongue tip, tongue lateral of the acute OLP group, but showed a tendency to decrease in circumvallate papilla, soft palate of the acute OLP group. 5. After treatment, electrical taste threshold was significant lower in soft palate of the OLP group than control group. 6. After treatment, NAS was significantly lower in soft palate of the OLP group than control group.

• Journal of the Korea Society of Computer and Information
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• v.16 no.2
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• pp.257-266
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• 2011

Over the society the trial for several systems to be connected with Network has been continued to share information and to make it various. In accordance with such a change, the concept of military warfare conduction has been changing form platform centric warfare in separate combat system based on network centric warfare in network based. We have continuously made an effort that we try to get the goal with efficient system which is linked up with network, but such a study on that one in military system analysis is still slower than the study out of military until now. So this study is searching network influence factor by using military network with application of social network analysis method which is used broadly in the society and the science as well. At this time we search co-relationships between social network and the thing that we can analyse C2 time by effectiveness measurement means. By this study it has value of network influence factor identification for the growing network composition.

• Korean Journal of Heritage: History & Science
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• v.42 no.1
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• pp.62-70
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• 2009

The study was conducted from Jan. 11 to Jan. 12 2008 on 17 areas which were the wintering area of Aegypius monachus and where the birds were observed. In the study, a total of 1,912 individuals were observed to winter in the areas, which was larger than any previous observation. The study found that 1,500 individuals wintered in the central region of Korea including Gyeonggido and Kangwondo, which accounted for 78.45%, and 412 individuals (21.55%) in the southern region such as Gyeongbuk, Gyeongnam, Jeannam and Jejudo (Island). Given the number of individuals wintering by region, Jangdan Peninsula (777 individuals), Cheorwon (488 individuals) and Sancheonggun(193 individuals) were mostly found. In comparison with the previous studies, 20-30% of the individuals have moved south since 2006. This movement might be attributed to the suspension of feeding campaigns, but the birds still crowded some specific areas.

• Convergence Security Journal
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• v.18 no.1
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• pp.43-60
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• 2018

Recently, with the arrival of the 4th industrial revolution, the security risks are converging and complexly changing, and the demand of cybersecurity experts is increasing. Therefore, in this paper, it is the largest of the domestic educational institutions, it has the largest number of emissions talent, and selects the representative major field of humanities and society. Then, after analyzing the common curriculum in each major field, compare it with the training course of cybersecurity experts derived through existing previous research. Through analysis results, we try to design a retraining course for cybersecurity professional human resources. Utilizing the results of this research, it is expected that it will be used as the basic material necessary for the subjects of the re-curriculum education. It is also expected to contribute to resolving the supply-demand gap of cybersecurity professionals.

• Journal of Korean Society of Transportation
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• v.26 no.1
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• pp.15-24
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• 2008

Located in the middle of lanes, the station of a median exclusive bus lane generates pedestrian groups on the green light of a crosswalk and causes pedestrians delays passing the access section. For the purpose of showing these facts, the pedestrian analysis, on which the queuing theory is applied, is presented in this study. The Result is that the pedestrian environment was deteriorated (LOS D) compared to an exciting pedestrian analysis based on 15 minutes of pedestrian volume (LOS A). A pedestrian level of service has been reevaluated based on an arrival rate on the median bus station in order to examine whether the result reflects reality or not. In result, it was similar outcomes to this study.

• Korean Journal of Clinical Pharmacy
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• v.22 no.2
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• pp.95-102
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• 2012

HIV 치료를 위한 강력한 항바이러스 약물요법이 널리 사용됨에 따라 HIV에 감염된 상태에서 신장질환 발생 위험성을 지닌 채 오랜 기간 생존하는 환자들이 증가하고 있다. 본 연구는 국립중앙의료원 감염병 센터를 내원한 만18세 이상의 HIV 감염 환자를 대상으로 HIV 감염 환자에게 신기능 장애를 유발하는 위험인자를 평가하고자 환자군 대조군 연구를 후향적으로 실시하였다. 2006년 1월부터 2011년 3월까지 5년 3개월 동안 신기능이 저하된 모든 HIV 감염 환자를 환자군으로 하며, 정상 신기능을 가진 HIV 감염 환자들 중 대조군을 무작위로 선정하여 환자군과 대조군을 1:2의 비율로 하였다. 환자군과 대조군을 비교해 만성신질환을 유발하는 위험인자를 평가하기 위한 분석변수로 성별, 연령, CD4+ 세포수, 혈중 바이러스 수, HAART 56일 이상 여부, 당뇨병과 C형 간염을 선정하였다. 또한 추가적으로 개별 antiretroviral 약물들 사용과 신기능이 얼마나 관련되어 있는지 알아보기 위해 각각의 약물과 eGFR의 상관관계를 분석하였다. 환자군은 CD4+ 세포수가 < $200{\times}10^6$ cells/l 인 군이 7.7배(OR: 7.7; 95% CI, 1.8-32.9) 단백뇨가 있는 환자의 경우 7.8배(OR: 7.8; 95% CI, 1.6-37.8) 더 유의하게 만성신질환 발생위험이 높았다. 개별 antiretroviral 약물들과 eGFR의 상관관계를 분석한 결과, lamivudine 이 eGFR 과 약한 음적 상관관계를 보이는 것으로 나타났으며(r = -.211, p < .05), 다른 약물들의 경우 통계적으로 유의한 값을 보이지 않았다. 이번 환자군-대조군 연구는 HIV 감염 환자들이 만성 신질환으로 발전하는데 여러 인자들의 역할에 대해 평가하고자 하였다. 여러 변수들을 평가해 본 결과, 만성 신질환 환자들의 경우 CD4+ 세포수가 < $200{\times}10^6$ cells/l 이거나 단백뇨를 동반한 경우가 통계적으로 유의하게 많았다.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.35 no.6
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• pp.1339-1345
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• 2015

Korean government annually estimates and reports the traffic safety index to evaluate the traffic safety of 228 Gu Gun. However, since the traffic safety index is derived from the spatially macroscopic perspective based on collected relative data, there are a couple of problems such as inability to investigate the individual traffic accidents on the spot, insecurity of accuracy and reliability of traffic safety index estimation method, and absence of establishing temporal relationship of traffic accidents. Thus, this study investigated temporal traffic safety in macroscopic manner for Gu Gun in Busan depending on the installation of the traffic safety facility (i.e., urban median), employing meta analysis. As a result, all Gu Gun in Busan except Saha, Buk, Dong, and Busanjin experienced more traffic accidents after installing the urban median, indicating that there are more rooms for improvement of macroscopic traffic safety evaluation.

• Journal of Digital Convergence
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• v.17 no.1
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• pp.1-8
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• 2019

The purpose of this study is to analyze the employment trends of autonomous automobile industry which is related to the 4th Industrial Revolution. Previously, big data of the employment trends were divided into skill field and task field. As a result, if a company was employed in the field of skill field, it was required to have talent in which personality traits and innovation traits were prominent. Second, if the task field is a production worker, it is desirable to have talented person with outstanding personality traits. In addition, if the task field is management, it has been confirmed that communication qualities require outstanding talent. The results of this study suggest that it is possible to use the data as a basic data for finding an effective employment strategy by identifying the characteristics of the talented person and considering the suitability of the tendency of hiring.