• Radiation Oncology Journal
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• v.16 no.3
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• pp.325-335
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• 1998

Purpose : Since the mid cranial fossa is composed of various thickness of bone, the tissue inhomogeneity caused by bone would produce dose attenuation in cobalt-60 gamma knife irradiation. The correction factor for bone attenuation of cobalt-60 which is used for gamma knife source is -3.5$\%$. More importantly, nearly all the radiosurgery treatment planning systems assume a treatment volume of unit density: any perturbation due to tissue inhomogeneity is neglected, This study was performed to confirm the bone attenuation in mid cranial fossa using gamma knife. Materials and Methods : Computed tomography was performed after Leksell stereotactic frame had been liked to the Alderson Rando Phantom (human phantom) skull area. Kodak X-omat V film was inserted into two sites of pituitary adenoma point and acoustic neurinoma point, and irradiated by gamma knife with 14mm and 18mm collimator. An automatic scanning densitometer with a 1mm aperture is used to measure the dose profile along the x and y axis. Results : Isodose curve constriction in mid cranial fossa is observed with various ranges. Pituitary tumor point is greater than acoustic neurinoma point (0.2-3.0 mm vs 0.1-1.3 mm) and generally 14 mm collimator is greater than 18mm collimator (0.4-3.0 mm vs. 0.2-2.2 mm) Even though the isodose constriction is found, constriction of 50$\%$ isodose curve which is used for treatment reference line does not exceed 1 mm. This range is too small to influence the treatment planning and treatment results. Conclusion : Radiosurgery planning system of gamma knife does not show significant error to be corrected without consideration of bone attenuation.

• Journal of Institute of Control, Robotics and Systems
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• v.3 no.2
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• pp.139-148
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• 1997

본 논문에서는 비선형 마찰이 존재하는 조준경 안정화 시스템에 대해서 마찰력 보상과 성능개선을 위한 신경망제어기의 설계방법을 제시한다. 제안한 신경망제어기는 비례, 적분, 진상(PI/LEAD) 제어기와 신경회로망과의 병렬로 구성되며, 제어 목적은 비선형 마찰과 외란이 존재하여도 안정거울의 각속도 추적성능과 안정화 성능의 향상에 있다. 신경회로망의 입력으로 안정거울의 각속도 추적오차와 추적오차의 적분, 제어입력이 필터를 통과한 신호가 사용되며, 신경호로망은 간접학습구조에 의해 학습된다. 조준경 시스템의 비선형 마찰력인 쿨롱마찰력의 크기가 외부환경에 따라 변하는 경우와 시스템으로 외란이 인가되는 경우에 대하여도 제안한 병렬제어기는 기존의 PI/LEAD 제어기보다 추적과 안정화 성능면에서 우수함을 컴퓨터 모의 실험으로 확인한다.

• The Korean Journal of Nuclear Medicine
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• v.22 no.2
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• pp.205-207
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• 1988

이제까지 슬관절 파열의 진단에는 관절조영술이나 관절경검사가 주로 이용되어 왔다. 저자들은 골스캔을 이응해서 슬관절 반월판 파열의 진단을 시도하였다. 슬관절 조영술이나 관절경검사로 확진된 반월판 파열 환자 7명에 대해 $^{99m}Tc-MDP$와 $^{99m}Tc-PYP$, 20mCi를 주사해서 동적, 정적영상 및 바늘구명 조준기를 이용한 영상을 얻었다. 그 소견은 1) 동적영상에서 반월판 손상부위의 혈류가 국소적으로 증가되었고, 2) 정적영상 및 바늘구멍 조준기를 이용한 영상에서 손상 부위의 경골과(tibial plateau)를 따라 특징적으로 얇은판 모양의 방사능 집적을 관찰할 수 있었다. 슬관절의 골신티그래피는 반월판 파열의 유용한 진단 방법으로 사료된다.

• 대한핵의학회:학술대회논문집
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• 1981.05a
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• pp.130.3-131
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• 1981

• The Korean Journal of Nuclear Medicine
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• v.39 no.6
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• pp.445-455
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• 2005

Purpose: We developed an animal SPECT system using clinical Philips ARGUS scintillation camera and pinhole collimator with specially manufactured small apertures. In this study, we evaluated the physical characteristics of this system and biological feasibility for animal experiments. Materials and Methods: Rotating station for small animals using a step motor and operating software were developed. Pinhole inserts with small apertures (diameter of 0.5, 1.0, and 2.0 mm) were manufactured and physical parameters including planar spatial resolution and sensitivity and reconstructed resolution were measured for some apertures. In order to measure the size of the usable field of view according to the distance from the focal point, manufactured multiple line sources separated with the same distance were scanned and numbers of lines within the field of view were counted. Using a Tc-99m line source with 0.5 mm diameter and 12 mm length placed in the exact center of field of view, planar spatial resolution according to the distance was measured. Calibration factor to obtain FWHM values in 'mm' unit was calculated from the planar image of two separated line sources. Te-99m point source with i mm diameter was used for the measurement of system sensitivity. In addition, SPECT data of micro phantom with cold and hot line inserts and rat brain after intravenous injection of [I-123]FP-CIT were acquired and reconstructed using filtered back protection reconstruction algorithm for pinhole collimator. Results: Size of usable field of view was proportional to the distance from the focal point and their relationship could be fitted into a linear equation (y=1.4x+0.5, x: distance). System sensitivity and planar spatial resolution at 3 cm measured using 1.0 mm aperture was 71 cps/MBq and 1.24 mm, respectively. In the SPECT image of rat brain with [I-123]FP-CIT acquired using 1.0 mm aperture, the distribution of dopamine transporter in the striatum was well identified in each hemisphere. Conclusion: We verified that this new animal SPECT system with the Phlilps ARGUS scanner and small apertures had sufficient performance for small animal imaging.

• Progress in Medical Physics
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• v.13 no.1
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• pp.37-43
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• 2002

Effect of scatter media materials and thickness, located between radioactivity and small gamma camera, on imaging characteristics was evaluated. The small gamma camera developed for breast imaging was consisted of collimator, NaI(T1) crystal(60$\times$60$\times$6 ㎣), PSPMT(position sensitive photomultimplier tube), NIMs and personal computer. Monte Carlo simulation was performed to evaluate the system sensitivity with different scatter media thickness(0~8 cm) and materials(air and acrylic) with parallel hole collimator and diverging collimator. The sensitivity and spatial resolution was measured using the small gamma camera with the same condition applied to the simulation. Counts was decreased by 10%(air) and 54%(acryl) with the parallel hole collimator and by 35%(air) and 63%(acryl) with the diverging collimator. Spatial resolution was decreased as increasing the thickness of scatter media. This study substantiate the importance of a gamma camera positioning and the minimization of the distance between detector and target lesion in the clinical application of a gamma camera.

• The Korean Journal of Nuclear Medicine
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• v.26 no.1
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• pp.160-163
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• 1992

유골골종(osteoid osteoma)은 특징적으로 직경 약 1cm미만의 원형 또는 타원형의 유골질제부(nidus)가 병소의 중심부에 있고, 그 주위는 반응성골질로 둘러싸여 있다. 그러므로 반응성골질 병소에서 제부의 확인은 유골골종의 진단에 매우 중요하다. 더우기 유골골종의 치료는 반드시 제부를 제거하여야 하기 때문에, 제부의 위치를 정확히 아는 것이 중요하다. 그러나, 유골골종의 제부는 단순 X-선 촬영상에서 잘 안나타나는 경우가 많아 진단에 어려움이 있다. 또한 골스캔도 유골골종의 진단에 많이 이용되고 있으나, 단순 신티그램에서 제부의 정확한 위치 파악은 어렵다. 이에 저자들은 바늘구멍조준기 골스캔을 시행하여 유골골종 제부에는 아주 진한 동위원소 집적이 보였고 주위의 반응성 골질 부위에는 제부보다 약한 동위원소 집적이 보여 특징적인 '이중 농도 집적' 소견을 얻었기에 바늘구멍조준기 골스캔이 유골골종의 진단에 매우 유용한 검사로 사료되어 보고하는 바이다.

• Journal of the Institute of Convergence Signal Processing
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• v.8 no.3
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• pp.156-162
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• 2007

The parallel beam SPECT system acquires projection data by using collimators in conjunction with photon detectors. The projection data of the parallel beam SPECT system is, however, blurred by the point response function of the collimator that is used to define the range of directions where photons can be detected. By increasing the number of parallel holes per unit area in collimator, one can reduce such blurring effect. This approach also, however, has the blurring problem if the distance between the object and the collimator becomes large. In this paper we consider correction methods for artifacts caused by non-circular orbit of parallel beam SPECT with many parallel holes per detector cell. To do so, we model the relationship between the object and its projection data as a linear system, and propose an iterative reconstruction method including artifacts correction. We compute the projector and the backprojector, which are required in iterative method, as a sum of convolutions with distance-dependent point response functions instead of matrix form, where those functions are analytically computed from a single function. By doing so, we dramatically reduce the computation time and memory required for the generation of the projector and the backprojector. We conducted several simulation studies to compare the performance of the proposed method with that of conventional Fourier method. The result shows that the proposed method outperforms Fourier methods objectively and subjectively.

• Journal of the Korean Society of Radiology
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• v.14 no.5
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• pp.563-575
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• 2020

The purpose of this study is to evaluate the activation characteristics that occur in a linear accelerator for container security inspection. In the computer simulation design, first, the targets consisted of a tungsten (Z=74) single material target and a tungsten (Z=74) and copper (Z=29) composite target. Second, the fan beam collimator was composed of a single material of lead (Z=82) and a composite material of tungsten (Z-74) and lead (Z=82) depending on the material. Final, the concrete in the room where the linear accelerator was located contained magnetite type and impurities. In the research method, first, the optical neutron flux was calculated using the MCNP6 code as a F4 Tally for the linear accelerator and structure. Second, the photoneutron flux calculated from the MCNP6 code was applied to FISPACT-II to evaluate the activation product. Final, the decommissioning evaluation was conducted through the specific activity of the activation product. As a result, first, it was the most common in photoneutron targets, followed by a collimator and a concrete 10 cm deep. Second, activation products were produced as by-products of W-181 in tungsten targets and collimator, and Co-60, Ni-63, Cs-134, Eu-152, Eu-154 nuclides in impurity-containing concrete. Final, it was found that the tungsten target satisfies the permissible concentration for self-disposal after 90 days upon decommissioning. These results could be confirmed that the photoneutron yield and degree of activation at 9 MeV energy were insignificant. However, it is thought that W-181 generated from the tungsten target and collimator of the linear accelerator may affect the exposure when disassembled for repair. Therefore, this study presents basic data on the management of activated parts of a linear accelerator for container security inspection. In addition, When decommissioning the linear accelerator for container security inspection, it is expected that it can be used to prove the standard that permissible concentration of self-disposal.

• 대한핵의학회:학술대회논문집
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• 2004.11a
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• pp.403.2-403.2
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• 2004