• Journal of Life Science
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• v.32 no.7
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• pp.532-541
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• 2022

Obesity induced by high-fat diet (HFD) is verified as a strong risk factor and negative prognostic factor for prostate cancer in several genetically engineered mice although it was not examined in the normal mice. To investigate whether HFD-induced obesity can affect the development and progression of cancer in the prostate of normal mice, alterations in the weight and histological structure of the prostate as well as the expression of cancer-related proteins were analyzed in obese C57BL/6N mice fed with 60% HFD for 16 weeks. First, HFD-induced obesity, including an increase in organ weight, body weight, fat accumulation, and serum lipid profile, was successfully induced in C57BL/6N mice after HFD treatment. The total weight of the prostate significantly increased HFD-induced obesity in the model mice compared with the control group. Among the four lobes of the prostate, the weight of the ventral prostate (VP) and anterior prostate (AP) were higher in HFD-induced obesity model mice than in the control group, although the weights of the lateral prostate (DLP) and seminal vesicle (SV) were constantly maintained. In addition, the incidences of hyperplasia and non-hodgkin's lymphoma (NHL) in the histological structure were remarkably increased in HFD-induced obesity model mice, while the epithelial thickness was higher in the same group. A significant increase in the phosphorylation levels of key proteins in the AKT (protein kinase B) signaling pathway was detected in HFD-induced obesity model mice. Therefore, these results suggest that HFD-induced obesity can promote hyperplasia and NHL in the prostates of C57BL/6N mice through the activation of the AKT signaling pathway.

• Journal of the Korean Society of Radiology
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• v.16 no.3
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• pp.225-231
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• 2022

Transcendence of space and time, virtual reality, augmented reality, etc. are being realized through the latest technologies in the era of the 4th industrial revolution. In a situation where they are currently experiencing artificial intelligence, augmented reality, big data, etc., the degree of interest in the latest technologies of the 4th industrial revolution for radiology students, the necessary competencies in the 4th industrial revolution era, and the prospect of the radiation field employment environment in the 4th industrial revolution era The purpose of this study was to find out the level of awareness of From February 7th to February 18th, 2022, surveys on awareness were analyzed using questionnaires for 2nd and 3rd year students in the Department of Radiology at S University in Daegu. As a result of the study, the level of interest in 3D modeling was shown to be the highest with an average of 3.34 ± 1.09 points, and interest in big data and artificial intelligence was also shown with an average of 3.27 ± 1.17 and 3.33 ± 1.07 points. In addition, the correlation between the awareness of the necessary competencies in the 4th industrial revolution era and the awareness of the prospects for employment in the radiation field in the 4th industrial revolution era was the highest (r=0.778, p<0.01), and the interest in the latest technologies in the 4th industrial revolution and the 4th industrial revolution It was found that there was also a correlation between the perceptions of the necessary capabilities of the times (r=0.694, p<0.01). In the era of the 4th industrial revolution, it is judged that it is necessary to strengthen professional education that can handle the latest technologies such as 3D printing, artificial intelligence, and big data, and to strengthen employment capabilities related to the latest technologies in the field of radiation medical technology.

• Journal of Korea Entertainment Industry Association
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• v.14 no.6
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• pp.279-287
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• 2020

This study aims to put forth an efficient way of improving body shapes by examining the effects of deep tissue massage and illite-combined deep tissue massage on body shape changes, and identifying body shape changes when applying each method. This study targeted twenty women in their thirties, and ten separate subjects were placed in different groups. Then deep tissue massage and illite-combined deep tissue massage were performed once a week, for a total of eight weeks. Moire Topography was applied before the experiments, four weeks later and eight weeks later to compare changes in spinous process inclination, shoulders and hips. The data collected were analyzed using SPSS v. 21.0, and the study results are as follows. In relation to general characteristics of the subjects, professionals occupied the highest proportion of them, and 90% of them were married. Here, 77.8% of them had experience in giving birth, and 78.6% of them chose natural birth. In addition, 57.1% of the subjects holding a majority had two children. When measuring spinous process inclination, shoulders and hips in the illite-combined deep tissue massage group and in the deep tissue massage group before the experiments, the illite-combined deep tissue massage group showed somewhat higher values in every area than the deep tissue massage group, but no statistically significant differences were not found, which means the homogeneity existed between them. When comparing body shape changes between the two massage methods, there were significant differences(p<.05, p<.01), because the illite-combined deep tissue massage group showed a much higher decline in spinous process inclination, shoulders and hips than the deep tissue massage group. This implies illite-combined deep tissue massage was more effective in improving body shapes than deep tissue massage. Therefore, illite-combined deep tissue massage is considered to be helpful in improving body shapes, and it is anticipated that this massage method can be used in relevant fields, including the skin care industry.

• 한국노년학
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• v.40 no.4
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• pp.729-746
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• 2020

For the development and better use of information and communication technology(ICT) for promoting health and quality of life in older people, it is important to understand personal factors associated with ICT use. The aims of this study were to describe the pattern of ICT use according to health characteristics of elderly and to investigate significant factors related to ICT use among three age groups. The data of 2017 National Survey of Older Koreans was used for analysis and 10,058 of older adults aged 65 and over were included for study participants. As results, first, the young old(65~74) used more functions of ICT than the middle-old(75~84) and the old-old(85 and over). Second, ICT was more used among older people with good conditions in chronic disease, subjective health, cognition, depression, vision, hearing, walking and IADL. Third, higher prevalence of ICT use was significantly associated with age, education, household income, subjective health, depression, cognitive function, vision limitation and walking limitation. Fourth, factors influencing the use of ICT were a little different among three age groups. For the young-old(65~74), subjective health, depression, cognitive decline, walking limitation, and IADL disability were significant factors affecting on ICT use. For the middle-old(75-84), subjective health, depression, cognitive decline, vision, hearing, and walking limitation were related with their ICT use. For the old-old(85 and over), only cognitive function and depression were associated with their ICT use. Based on these results, this study suggested the need to consider multiple health conditions for developing and using ICT for older adults.

• Korean Journal of Environment and Ecology
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• v.36 no.4
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• pp.361-367
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• 2022

This study was conducted to identify annual variation of observation and activity pattern of Korean chipmunk (Tamias sibiricus) using camera traps in the Seoraksan and Jirisan National Parks, South Korea from May 2019 to May 2021. The annual variation was identified based on the observed frequency through weekly observations. Daily activity patterns of the species were also analyzed by season. The daily activity pattern of chipmunk appeared to be constantly diurnal across the years regardless of habitat or season. The Korean chipmunks living in the two different regions were observed in different time periods throughout the year. While the chipmunks inhabiting the Seoraksan were observed from 18^th to 45^th week, the chipmunks inhabiting the Jirisan National Park were observed from 7^th to 48^th week. This may be influenced by the hibernation period of chipmunks in the two different regions. In both regions, chipmunks were most frequently observed in autumn. It is considered that seasonal variation on population dynamic and activity patterns of chipmunks were reflected in the observation frequency. Although the observation frequency of camera trap is an indirect indicator and thus having a limitation that it cannot distinguish the population density and amount of activity for the target species, camera trapping is still an effective survey technique for monitoring mammals due to its high accessibility and easy use.

• Korean Journal of Plant Resources
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• v.35 no.5
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• pp.652-658
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• 2022

This study was conducted to induce somatic embryogenic callus (SEC) derived from petals in rose. The petal explants of 3 cultivars ('Ice Wing', 'Orange Eye' and 'Pink Beauty') with different flower colors were placed on three types media (MS, SH and WPM) supplemented with 11 mg/L 2,4-D, respectively, and then cultured in the dark for 47 days. Calluses were formed at explants of all three cultivars. Also, 'Ice Wing', which were cultured in the SH as the basal medium, showed the highest callus formation rate. However, somatic embryos were generated from only petal-derived callus of 'Ice Wing', which were induced on the WPM as the basal medium, transferred it to SH basal medium supplemented with 3 mg/L 2,4-D, and 300 mg/L L-proline, and cultured for 5 weeks. The SEC has been proliferated every four weeks at the subculture interval. In addition, as a results of making a comparison of expression of RhSERK3 and RhSERK4, which is used as signal for generation of somatic embryo from callus in rose, between the SEC and petal-derived callus from 'Ice Wing' by RT-qPCR, the former showed 10 times higher RhSERK3 expression and 700 times higher RhSERK4 expression than the latter.

• Journal of agricultural medicine and community health
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• v.47 no.3
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• pp.181-188
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• 2022

Objectives: The prevalence of diabetes mellitus was approximately 16% in populations of over age 30 years, and deaths from diabetes mellitus became the sixth most prevalent cause of death by disease. To assess the relationship between HbA1c and heavy metal level in blood and urine, targeted residents were evaluated in a vast steel industrial complex. Methods: We selected 414 subjects for analysis after applying the following exclusion criterion: 18 persons with diabetes mellitus. They took part in a questionnaire survey and underwent blood and urinary assessments. HbA1c and lead (Pb) level were measured in blood and, cadmium (Cd), inorganic arsenic (iAs) and mercury (Hg) were evaluated in urine. Two subgroups were divided by HbA1c 6.5%. Each subgroup was divided by 10th, 20th, 30th, 40th, 50th, 60th, 70th, 80th and 90th percentile levels of biological exposure index of the heavy metals for logistic regression. Results: Odd ratios have a tendency to increase as they go from the 90th to the 10th percentile of cadmium. However, lead, arsenic and mercury did not have significant relationships with HbA1c. In correction of age, region, gender and smoking history, a higher distribution in the subgroup with cadmium above 0.8318 ㎍/g creatinine (30th percentile) was demonstrated in the subgroup with HbA1c levels above the 6.5%, with an odds ratio of 5.26 (95% C.I. ; 1.44~19.17). Conclusion: This study found a significant correlation between urinary levels of cadmium and HbA1c in correction of several factors. It is meaningful that this outcome may be used as a basis for a study to establish the acceptable limit of urinary cadmium in Korea.

• Korean Journal of Food Science and Technology
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• v.53 no.4
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• pp.399-407
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• 2021

Wrinkle formation and dryness are the most well-known symptoms of skin aging. This study investigated skin anti-aging and moisturizing effects of Mugunghwa (Hibiscus syriacus L.), the national flower of Korea. The effect of H. syriacus L. flower extract was examined in skin cells originating from humans in vitro and in hairless mice exposed to UVB in vivo. The in vivo study results showed that skin hydration-related factors such as involucrin, filaggrin, HAS1, HYAL1, and matrix metalloproteinase-I (a primary skin photoaging factor) were regulated by H. syriacus L. Additionally, epidermal thickness and collagen disruption, which resulted in wrinkle formation and skin dryness, were ameliorated by oral administration of H. syriacus L. These results indicate that H. syriacus L. flowers can play important roles in preventing aging and promoting skin moisturizing.

• Journal of the Korean Chemical Society
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• v.65 no.3
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• pp.197-202
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• 2021

In this study, activated clay treated with H₂SO₄ (20% by weight) and heat at 90 ℃ for 8 h for acid white soil was used as an adsorbent for the removal of PO₄^3--P in water. Prior to the adsorption experiment, the characteristics of activated clay was examined by X-ray Fluorescence Spectrometry (XRF) and BET surface area analyser. The adsorption of PO₄^3--P on activated clay was steeply increased within 0.25 h and reached equilibrium at 4 h. At 5 mg/L of low PO₄^3--P concentration, roughly 98% of adsorption efficiency was accomplished by activated clay. The adsorption data of PO₄^3--P were introduced to the adsorption isotherm and kinetic models. It was seen that both Freundlich and Langmuir isotherms were applied well to describe the adsorption behavior of PO₄^3--P on activated clay. For adsorption PO₄^3--P on activated clay, the Freundlich and Langmuir isotherm coefficients, K_F and Q, were found to be 8.3 and 20.0 mg/g, respectively. The pseudo-second-order kinetics model was more suitable for adsorption of PO₄^3--P in water/activated clay system owing to the higher correlation coefficient R² and the more proximity value of the experimental value q_e,exp and the calculated value q_e,cal than the pseudo-first-order kinetics model. The results of study indicate that activated clay could be used as an efficient adsorbent for the removal of PO₄³-P from water.

• Journal of the Korean Society of Marine Environment & Safety
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• v.27 no.2
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• pp.275-285
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• 2021

COVID-19 is threatening the safety of ships and seafarers by delaying seafarer rotation. Shipping companies and governments have a blindspot in case of the onboard environment of seafarers. An effective, alternative plan should be devised to eliminate the possibility of human accidents in an emergency that threatens the safety of seafarers. According to the survey of former and current seafarers, the most important factor in boarding life was safety, and the most necessary thing during emergencies was to secure smooth seafarer rotation rather than improve wages and welfare. By analyzing the major routes of national shipping companies by continent, ports with a large number of calls and a high Air Connectivity Index were selected as the base port. In addition, the route was designed for effective, domestic seafarer rotation during international shipping. Other countries must be consulted to establish a travel route linking ships, ports, and airports for the safe return of sailors to their home countries during an emergency. In addition, it is necessary to work together for the seafarers who are in trouble of seafarer rotation through cooperation with the International Maritime Organization(IMO). Starting with this, the government should have a monitoring system for the return and non-return routes as well as the number of seafarers on board. If such a system is established, it will be able to determine the response direction of our country's policy in case of an emergency. Along with the shipping company's ef orts to improve the treatment of seafarers, national and social attention will be needed to review domestic laws and improve awareness about seafarers.