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A Case of Hypophosphatemic Rickets associated with Epidermal Nevus Syndrome (저인산혈증성 구루병을 동반한 표피모반증후군 1례)

  • Lee Yong Joo;Kang Ju Hyung;Lee Soo Jin;Park Ho Jin;Shin Choong Ho;Cheong Hae Il
    • Childhood Kidney Diseases
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    • v.9 no.2
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    • pp.263-268
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    • 2005
  • Epidermal nevus syndrome is a rare disease consisting of epidermal nevus and multisystem pathologic conditions associated with anomalies in the central nervous system, bone, eye, heart, vasculature and genito-urinary system. Hypophosphatemic rickets has been rarely observed in association with this syndrome. We report a case of hypophosphatemic rickets as sociated with epidermal nevus syndrome with review of the literature. (J Korean Soc Pediatr Nephrol 2005;9:263-268)

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Homogenization Analysis of Problems related to Quartz Dissolution and Hydroxide Diffusion (석영광물의 용해 및 수산화 이온의 확산에 관한 균질화해석)

  • Choi, Jung-Hae;Ichikawa, Yasuaki
    • The Journal of Engineering Geology
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    • v.20 no.3
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    • pp.271-279
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    • 2010
  • Time-dependent behavior similar to secondary deformation related to mineral dissolution is easily observed when performing a laboratory pressure experiment. In this research, to observe the dissolution of quartz found in bentonite used as buffer material for the geological disposal of high-level waste (HLW) under conditions of high pH, we calculated the diffusion of $OH^-$ ions and the behavior of quartz dissolution using the homogenization analysis method. The results reveal that the rate of quartz dissolution is proportional to the temperature and interlayer water thickness. In particular, in a high-pH environment, the reacted area (and therefore the dissolution rate) increases with decreasing interlayer water thickness.

Mutagenicity studies of food and cosmetic dyes (1) (식용 및 외용색소의 유전독성에 관한 연구 (1))

  • 하광원;정해관;오혜영;허옥순;손수정;한의식;정성철;한순영;최선주
    • Journal of Food Hygiene and Safety
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    • v.8 no.3
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    • pp.171-179
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    • 1993
  • The mutagenicity of 22 food and cosmetic dyes had been evaluated. Two different short-term mutagenicity tests were used: (1) Salmonella typhimurium preincubation assay (Ames test) (2) Chromosome aberration test with cultured Chinese hamster lung (CHL) fibroblast cells. Orange No. 203 was mutagenic in Salmonella typhimurium with and without rat liver microsomal activation, and Red No. 204 was mutagenic in Salmonelhl typhimurium with rat liver microsomal activation. Red No. 104-1 and Red No. 215 showed slight increase of chromosomal aberration in CHL cells.

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현장탐방 - (주)성아테크 가락시장 시설현대화사업 제1단계 신축공사

  • 대한설비건설협회
    • 월간 기계설비
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    • s.292
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    • pp.70-78
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    • 2014
  • 가락동 농수산물도매시장은 지난 1985년 개설된 국내 최초 공영도매시장이자 연간 230만톤 거래 규모의 세계 최대 도매시장으로 서울시민 농수산 먹거리의 약 50%를 담당하고 있으며 전국 공영도매시장 물량의 약 33%를 처리하는 등 전국 농수산물 유통의 중추 기능을 담당하고 있다. 가락시장은 5,000여개 유통업체가 영업 중이며 하루 이용객은 13만명, 출입차량은 6만7,000대에 달할 정도로 과부하를 겪고 있다. 또한 도시 주거환경을 저해하는 혐오시설로 치부돼 이전 압박을 받아왔으며 전반적인 시설 노후화와 유통 수요에 부적합한 물류구조, 주변 교통정체 야기 등의 문제로 시설현대화 필요성도 제기되어 왔다. 이에 따라 서울시농수산식품공사가 지난 2009년 재건축을 통한 시설현대화 사업을 발표하고 기존의 시장 기능을 유지하면서 재건축을 하는 순환식 시설현대화 사업을 3단계(당초 계획은 2009년~2018년까지 10년 예상했으나 가락시장 계획변경 타당성 검토용역 결과에 따라 2025년까지 지연될 것으로 예상됨)에 걸쳐 추진키로 했다. 이에 따라 1단계 사업은 지난 2011년 6월부터 진행되어 2015년 2월 준공 예정이다. 본지는 가락시장 시설현대화 1단계 공사에서 기계설비 및 소방공사를 담당한 (주)성아테크(대표 정해돈) 이완식 현장소장과 시공사인 대림산업(주) 박승재 현장소장을 만나 현장 이야기를 들어 보았다.

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Detection of Benzene Metabolite Induced Aneuploidy and Translocation in HL-60 Cells by Fluorescence in situ Hybridization using Whole Chromosome-specific Probes for Chromosome 8 and 21 (벤젠 대사산물에 의해 유도된 HL-60 세포의 8번 및 21번 염색체의 이수성 및 상호전좌)

  • 김수영;정해원
    • Environmental Mutagens and Carcinogens
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    • v.22 no.2
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    • pp.90-96
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    • 2002
  • Benzene is a widespread human carcinogen, inducing leukemia and hematotoxicity. Exposure to benzene metabolites has been shown to cause genetic damage, including aneusomy and chromosome aberrations. Fluorescence in situ hybridization(FISH) procedure was used to determine if the benzene metabolite, 1, 2, 4-benzenetriol(BT), hydroquinone(HQ) and trans, trans-muconic acid(t,t-MA) induced specific chromosomal change in HL-60 cells. Treatment with BT, HQ and t,t-MA resulted in the induction of monosomy 8 and 21 in HL-60 cells in a dose-dependent manner. All of these metabolites also induced trisomy 8 and 21, but no correlation between frequencies of trisomy and concentration was found. Translocations between chromosome 8 and another unidentified chromosome [t(8:\ulcorner)], and between chromosome 21 and another unidentified chromosome [t(8:21)] were found. However, translocation between chromosome 8 and 21 [t(8:21)] was not found. Results indicate that the benzene metabolites, BT, HQ and t,t-MA, induce chromosome specific numerical and structural aberrations, and the fluorescence in situ hybridization (FISH) approach may be a useful and powerful technique for detection of aneuploidy.

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Characterization of Electrostrictive Polyurethane Films for Micro-Actuators (전기왜곡성 폴리우레탄 엑츄에이터의 특성 평가)

  • Jeong, Eun-Soo;Park, Han-Soo;Jeong, Hae-Do;Jo, Nam-Ju;Jae, Woo-Seong
    • Journal of the Korean Society for Precision Engineering
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    • v.19 no.4
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    • pp.161-167
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    • 2002
  • For the purpose of applying to micro-actuator, thermal properties and displacement of electrostrictive polyurethane(PU) elastomers have been measured. In order to understand an effect of PU component, crosslinking agent are controlled by 0.5 wt% and 1 wt%. DMPA and anther chain extenders were used. PU sample that chain extenders are DMPA is added NaOH for comprehension of effect of ionic groups. The deposited electrode sire on PU films is equal to acrylic holder size when the displacement was measured. Dynamic response according to frequency, displacement and recovery time according to PU thickness were measured. 1 wt% crosslinking agent contents PU samples have higher displacement and lower recovery time than 0.5 wt% crosslinking agent contents PU. If the PU thickness is increased, the actuating voltage for generating of same displacement is increased, too.

Effects of Noise Power Uncertainty on Energy Detection for Spectrum Sensing (잡음 전력의 불확실성이 에너지 검파 기반의 스펙트럼 감지에 미치는 영향)

  • Lim, Chang-Heon
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.48 no.11
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    • pp.22-27
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    • 2011
  • In spectrum sensing, an energy detector compares the energy of a received signal with a predetermined detection threshold and decides whether a primary user is active or not in a licensed frequency band. Here the detection threshold is related to the noise power level in the band. Most previous works on energy detection have assumed that the noise power is exactly known a priori. However, this assumption does not hold in practice since there may be some uncertainty about the noise power. So it is necessary to investigate its effects on the performance of energy detection for spectrum sensing. In this paper, we analyze the effects using the residue theorem for contour integral and present the associated numerical results.

The Development of Evaluation Items for Each Stage of Public Informatization Projects Implementation (공공정보화사업 추진단계별 평가항목 개발)

  • Jung, Hae-Yong;Kim, Sang-Hoon
    • 한국IT서비스학회:학술대회논문집
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    • 2003.11a
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    • pp.323-333
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    • 2003
  • 본 연구에서는 정보화사업의 성과는 직접적으로 하나의 효과만을 발생시키지 않고 다양한 단계에서 다양한 형태의 성과로 발생된다는 점에서 정보화사업의 추진단계를 사업추진 전(前) 단계(사전평가), 사업추진 진행단계(진행평가), 사업추진 완료 후 운영단계(사후평가)로 구분하고 각 단계별로 정보화사업의 성과를 측정하기 위한 정보화사업 추진단계별 평가모형을 제시하였다. 각 추진단계별 평가영역 및 평가항목의 개발은 정보화사업 평가항목에 관한 선행연구들에 대한 이론적 고찰과 국내 외 공공부문에서 실제 적용하고 있는 사례를 중심으로 도출하였으며, 특히 본 연구에서의 중점연구대상 정보화사업인 문화정보화사업을 중심으로 제시하였다. 각 단계별 평가영역 및 평가항목으로는 사전평가에서는 사업추진 계획영역의 비용산정적정도, 사업적 타당도, 전략적 타당도, 위험도분석, 추진계획적정도의 5개의 평가항목으로, 진행평가에서는 사업추진 실행영역의 사업추진효율성, 자원관리적정도, 아웃소싱관리적정도 등 3개 평가항목을 제시하였다. 또한 사후평가에서는 정보시스템 구축성과 영역의 경우 시스템품질, 정본품질, IS 서비스 품질을, 정보시스템 운영성과 영역은 시스템의 활용도와 사용자 만족도를, 조직 및 경영성과 영역은 사업적 기여도와 전략적 기여도를 각각 제시하였으며, 아울러 각 평가항목별 세부 평가항목을 함께 제안하였다.

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A Study on the Step-Up Converter with the New Topology Method (내구성이 개선된 발전용 가스터빈 온도센서 개발에 관한 연구)

  • Lee, Young-Jun;Jung, Hai-Young
    • The Journal of the Korea institute of electronic communication sciences
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    • v.15 no.6
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    • pp.1175-1186
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    • 2020
  • In this study, the problem is analyzed, and methods of improvement are presented. For evaluating the performance of the proposed EGT sensor, a complex environment test equipment has been developed to test both high temperature and vibration conditions at the same time. This equipment evaluates the accuracy and response time of the EGT sensor. In the results of the comparison test of the complex environment test equipment of heat and vibration, the existing sensor showed a carbonization problem, and the proposed sensor showed no problem. Therefore, it is expected that the improved EGT sensor will be able to be applied to various industrial fields, including gas turbines for power generation.

A Feasibility Study of a Rainfall Triggeirng Index Model to Warn Landslides in Korea (산사태 경보를 위한 RTI 모델의 적용성 평가)

  • Chae, Byung-Gon;Choi, Junghae;Jeong, Hae Keun
    • The Journal of Engineering Geology
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    • v.26 no.2
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    • pp.235-250
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    • 2016
  • In Korea, 70% of the annual rainfall falls in summer, and the number of days of extreme rainfall (over 200 mm) is increasing over time. Because rainfall is the most important trigger of landslides, it is necessary to decide a rainfall threshold for landslide warning and to develop a landslide warning model. This study selected 12 study areas that contained landslides with exactly known triggering times and locations, and also rainfall data. The feasibility of applying a Rainfall Triggering Index (RTI) to Korea is analyzed, and three RTI models that consider different time units for rainfall intensity are compared. The analyses show that the 60-minute RTI model failed to predict landslides in three of the study areas, while both the 30- and 10-minute RTI models gave successful predictions for all of the study areas. Each RTI model showed different mean response times to landslide warning: 4.04 hours in the 60-minute RTI model, 6.08 hours in the 30-minute RTI model, and 9.15 hours in the 10-minute RTI model. Longer response times to landslides were possible using models that considered rainfall intensity for shorter periods of time. Considering the large variations in rainfall intensity that may occur within short periods in Korea, it is possible to increase the accuracy of prediction, and thereby improve the early warning of landslides, using a RTI model that considers rainfall intensity for periods of less than 1 hour.