• Proceedings of The Korean Cleft Lip And Palate Association
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• 1998.06a
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• pp.25-25
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• 1998

• YAKHAK HOEJI
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• v.35 no.2
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• pp.119-122
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• 1991

A convenient method for the synthesis of ibuproxam, which is a non steroidal antiinflammatory agent, is reported. Friedel-Crafts reaction of isobutylbenzene with ethyl $\alpha$-chloro-$\alpha$-(methylthio)acetate (3) gives ethyl $\alpha$-methylthio-(p-isobutylpheny) acetate (4). Ethyl 2-methylthio-2-(4-isobutylphenyl) propionate (5) is obtained from methylation of the compound (4) with NaH and Mel. lbuproxam (7) is easily synthesized by reductive desulfurization of the compound (5) with zinc dust-acetic acid or Raney nickel, followed by treatment of the resultant ethyl 2-(4-isobutyl-pheny) propionate (6) with H$_{2}$NOH-HCI.

• YAKHAK HOEJI
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• v.35 no.2
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• pp.131-134
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• 1991

A new method for the synthesis of butibufen, which is a non steroidal anti-iriflammatory agent, is described. Friedel-Crafts reaction of isobutylbenzene with ethyl $\alpha$-chloro-.alpha.-(methylthio) acetate (1) gives ethyl $\alpha$-methylthio-(p-isobutylphenyl)acetate (2). Ethyl 2-methylthio-2-(4-isobutylphenyl)butyrate (3) is obtained from treatment of the compound (2) with NaH and Etl. Butibufen (5) is synthesized by reductive desulfurization of the compound (3) with zinc dust-acetic acid or Raney nickel, followed by hydrolysis of the resultant ethyl 2-(4-isobutylphenyl)butyrate (4).

• Proceedings of the Korean Environmental Sciences Society Conference
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• 2017.10a
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• pp.165-165
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• 2017

• Proceedings of the Korean Environmental Sciences Society Conference
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• 2019.10a
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• pp.168-168
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• 2019

• 시스템엔지니어링워크숍
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• s.1
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• pp.165-168
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• 2003

A robot system in most industries has a complicated structure, which includes electric and electronic components, and mechanical parts. For this reason, building a robot system also has a very complicated design and maintenance processes. Especially to predict or assess the system's maintainability and safety is important for both designer and operator before it's production or installation of the system. This paper presents an application methodology of FMECA focused on safety in design of a robot system with point of view of reliability engineering.

• Proceedings of the Korean Institute of Communication Sciences Conference
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• 2004.07a
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• pp.471-471
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• 2004

• Proceedings of the Korean Institute of Communication Sciences Conference
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• 2004.07a
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• pp.352-352
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• 2004

• Proceedings of the KIEE Conference
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• 2001.07c
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• pp.1629-1630
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• 2001

The high voltage measuring systems used in the testing systems shall be required to maintain the traceability to the national or international standards by the IEC 60060-2. Also all testing laboratories should prepare the documents evaluating the measurement uncertainty of the tests. By the way, this paper introduces the principal of IEC about the maintenance of traceability and evaluation methode of uncertainty.

• The Bulletin of The Korean Astronomical Society
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• v.34 no.2
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• pp.52.1-52.1
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• 2009