• Journal of Chest Surgery
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• v.32 no.12
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• pp.1106-1110
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• 1999

배경: 다한증의 치료에 있어서 흉강경을 이용한 교감신경절제술의 시술 빈도가 급증하고 있다. 그러나 액와부 다한증의 경우 수장부나 안면 두부다한증에 비하여 절제범위가 광범위하여 이에 따른 보상성 다한증 및 기타 합병증의 발생의 높고 액취증이 동반되어있는 경우 장기적인 만족도가 낮아서 크게 각광 받지 못해왔다. 대상 및 방법: 본 교실에서는 1997년 3월부터 1999년 4월까지 45례의 액와부 다한증 환자에서 2 mm 흉강내시경을 이용하여 흉부교감신경절제술 또는 잘단술을 시행하였다. 남자 28례 여자 17례로 평균연령은 28(13-46세) 였고 평균추적기간은 10개월(1-24)이었다. 24례가 액와부에만 국한된 과도발한을 호소 하였고 2례에서 수술 전 심한 액취증이 동반되어있었다. 21례의 T3,4 교감신경절제술, 20례의 T2,4 교감신경단술 그리고 4례의 T4 교감신경절제수을 시행하여 즉각적인 증상치유효과 보상성 다한증 및 장기적 만족도를 비교 분석하였다. 중등도 이상의 흉막유착으로 5mm 내시경이 필요했던 2례을 제외한 전 환자에서 2mm 트로카 2개를 사용하여 수술을 하였다 결과: 평균수술시간은 T3,4 교감신경절제술이 46.2$\pm$11분 T2, 4 교감신경절단술이 32.5$\pm$23분 T4 교감신경절제술이 53.8$\pm$18분이 소요되었고 수술직후의 효과는 T3,4 교감신경절제술과 T2,4 교감신경절단술에서 '전혀땀이 나지 않는다'가 17례(81%) 와 12례(60%) '수술전보다 감소했으나 약간땀이 난다'가 4례(19%) 와 8례(40%) 로 모든 환자에서 효과가 있었으나 T4 교감신경절제술은 4례중3례(75%)에서 전혀 효과가 없었다. 보상성 다한증은 T3,4교감신경절제술과 T2,4 교감신경절단술에서 각각 67%, 60%로 나타났고 생활에 불편을 줄 정도의 심한경우는 10% 5%에 불과했으며 장기적인 만족도는 T3,4 교감신경절제술이 86% T2,4 교감신경절단술이 89%로 나타나 높은 성공률을 보았다 결론 : 액와부다한증의 치료에 있어서 T3,4 교감신경절제술과 T2,4교감신경절단술은 증상치유효과가 높고 절제범위의 제한에 따른 보상성 다한증의 감소로 장기적 만족도가 우수한 효과적인 방법이다. 액취증이 동반된 경우 이에대한 충분한사전 설명과 원인 감별후 적절한 보조요법을 병행함으로써 환자의 만족도를 높힐수 있다고 본다.

• Land and Housing Review
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• v.3 no.2
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• pp.127-136
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• 2012

The Korean government designated 10 innovation cities throughout the country in 2005 in order to resolve concentration on the capital region and to promote balanced development of localities. An innovation city is a future-type city equipped with environment for innovation and high-quality settlement environment in terms of residence, education and culture by accommodating public institutions and facilitating close cooperation among companies, universities and research institutes. Thus, for the early settlement and activation of innovation cities, this study suggested a plan to operate the current innovation city business centers from a mid- and long-term viewpoint rather than for a limited time. Through this study, we attempt to establish the roles of the centers so that they can play central roles in the move of public institutions, the development of industry-university-research institute clusters, the creation of innovations, and the spread of innovations, which are the goals of the development of public institutions, after the sites have been prepared.

• Journal of Korean Ophthalmic Optics Society
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• v.14 no.3
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• pp.43-49
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• 2009

Purpose: The purpose of this study was to obtain the fundamental data of dynamic visual acuity and dynamic stereoacuity. Methods: The subjects were 20 athletes (high school baseball player) and 40 nonathletes (20 male, 20 female). We assessed static visual acuity, dynamic visual acuity, static stereoacuity and dynamic stereoacuity using rotating mirror projection system and computer program. Results: Three groups had similar static visual acuity and static stereoacuity. On the other hand, the dynamic visual acuity and dynamic stereoacuity showed statistically significant differency. The mean dynamic visual acuity for athletes was 174.80${\pm}$28.70 deg/sec, 137.10${\pm}$16.54 deg/sec for male nonathletes and 111.59${\pm}$15.40 deg/sec for female nonathletes. The mean dynamic stereoacuity for athlets was 234.55${\pm}$19.64, 249.05${\pm}$8.86 for male nonathletes and 247.10${\pm}$14.89 for female nonathletes. The group of athletes had better dynamic visual acuity and dynamic stereoacuity. Conclusions: If the result of this study apply to sports, it will be very useful to improve sports performance.

• Journal of Physiology & Pathology in Korean Medicine
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• v.31 no.5
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• pp.264-269
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• 2017

Prunella vulgaris, well-known traditional medicinal plant, is used for the cure of abscess, scrofula, hypertension and urinary diseases. Diabetic nephropathy is the most common cause of end-stage renal disease. The pathological characteristics of diabetic nephropathy are glomerular and tubular basement membrane thickening. The aim of the present study was to evaluate the effect of Prunella vulgaris, on diabetic glomerular injury in streptozotocin-induced diabetes rats. Diabetes mellitus was induced by a single intraperitoneal injection of streptozotocin (STZ; 45 mg/kg) and confirmed by random glucose level higher than ${\leq}300mg/dL$. The experimental rats were divided into five groups: control group (Male SD rats), STZ group (Male SD rats injected STZ), Aminoguanidine group (Male SD rats injected STZ + AG 100 mg/kg/day), Low dose group (Male SD rats injected STZ + APV 100 mg/kg/day), High dose group (Male SD rats injected STZ + APV 300 mg/kg/day). AG or APVs were administered once a day for 8 weeks. Body weight and food/water intake were measured every four weeks. At the end of study, the kidneys were collected and cut into pieces for immunohistochemistry and western blot analysis. Our study showed that body weight and water/food intake were no significant differences between untreated STZ-induced diabetic rat and APV treated-STZ rat. However, phosphorylation of receptor-regulated Smads (Smad3) was significantly decreased in APV treated-STZ rat as compared with the diabetic group. In addition, APV was improved nephrin level in kidney tissue. Therefore, we suggest that APV has a protective effect against STZ-induced diabetic glomerular injury.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.5 no.1
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• pp.62-67
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• 2002

Purpose: The aim of this study was to investigate the age of onset and the prevalence of lactose malabsorption in early childhood in Korea. Methods: We conducted a study of lactose malabsorption by breath hydrogen test in healthy children aged between 25~96 months old. Standard lactose loading (2 g lactose/kg, maximum 40g) test was done in 129 children and cow's milk (10 mL/kg) loading in 126 children followed by breath sampling of 60 and 120 minutes after the loading. An increase above baseline of 20 ppm or more was used as a criteria for positive responses. Results: The prevalence of lactose malabsorption was 7% in 25~36 months old, 19% in 37~48 months old, 35% in 49~60 months old, 55% in 61~72 months old, 82% in 72~84 months old, 80% in 85~96 months old children. Only 1% of the children showed positive result in breath hydrogen test after the cow's milk challenge. Conclusion: The prevalence of lactose malabsorption was increased between 37 months and 60 months of age, reached to adult level of prevalence after 72 months of age. When physiological dose of lactose was used as the challenge, the number of lactose malabsorbers become clinically insignificant.

• Journal of Life Science
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• v.26 no.2
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• pp.155-163
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• 2016

Metabolism of lactate dehydrogenase (EC 1.1.1.27, LDH) was studied to identify the function of LDH-C. Tissues of LDH liver-specific Ldh-C expressed Carassius auratus and eye-specific Ldh-C expressed Lepomis macrochirus after starvation were studied. LDH activity in liver tissue from C. auratus was increased after starvation. And LDH specific activity (units/mg) and LDH/CS were increased in tissues. It means the anaerobic metabolism was taking place in C. auratus after starvation. LDH B₄ isozyme was decreased in skeletal muscle and increased in heart tissue. LDH C₄ isozymes those showed in eye and brain tissues were identified as liver-specific C₄ isozymes and disappeared after starvation. And C hybrid in eye, A₄ isozyme in brain, and both C hybrid and C₄ isozyme in liver tissue were increased, respectively. In L. macrochirus, the level of variation of LDH activities was low but greatly increased especially in eye tissue and LDH A₄ and AC hybrid were increased in brain tissue. The LDH activities in tissues from C. auratus and L. macrochirus remained 30.30-18.64% and 25-18.75%, respectively, as a result of the inhibition by 10 mM of pyruvate. The Km^PYR values of LDH in C. auratus were increased. As a result, LDH liver-specific C₄ isozyme was expressed in liver, brain and eye tissues during starvation. It seems metabolism of lactate was predominant in brain tissue. After starvation, the liver-specific LDH-C was affected more than eye-specific LDH-C.

• The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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• v.10 no.3
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• pp.139-144
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• 2005

To investigate the long-term variation of water qualities, we have daily monitored physio-chemical characteristics of surface water in the Geum River estuary from June 1996 to April 2004. We found that the water qualities were determined by three dominant factors : 1. fluvial input from Geum River ($28.3\%$), 2. chemical processes such as nitrification and phosphate addition originated from sediment resuspension and domestic sew- age input ($18.6\%$), 3. biological processes such as nutrient consumption by primary producers ($13.5\%$). The factor 1 (fluvial input) effectively affected the water quality of the estuary particularly during the normal or low river discharge. The factor 2 (chemical processes) and the factor 3 (biological processes) showed distinct seasonal differences due to their relative strengths of biological activities. The factor 3 was a governing parameter during the period of spring algal bloom in 2004. For the spring period, an empirical equation derived from the multi-regression analyses showed that the in-situ chlorophyll-a distributions in the estuarine water were successfully simulated by the phosphate concentrations and N/P ratios. Therefore we suggest that phosphate functions as a limiting factor for the primary productivity in the Geum River estuary for the dry season, especially during spring.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.9
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• pp.647-654
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• 2016

In the defense industry, national security takes priority over economic sense and this has translated into high cost and long-term research and development. However, the exponential growth of technology and rapid changes in the security situation in recent years have resulted in a call for the development of systems at a low cost within a short period of time. In order to implement a modularization strategy in the field of defense, the introduction of line replaceable units in OO systems needs to be prioritized. This study selects six criteria following a literature review and prioritizes 11 modules for OO systems using the project evaluation method, Grey Relational Analysis (GRA). Based on the GRA results, the grey relational grades were derived as 0.83, 0.81 and 0.80 for the M11 (Main board), M8 (EMI module), M3 (Single board computer) modules, respectively. The cost and time of development is expected to be reduced in accordance with the grey relational grade. The results of this research could be utilized for decision making on adopting modularization in similar system development or product improvement programs (PIPs).

• Journal of Korean Home Economics Education Association
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• v.29 no.3
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• pp.89-104
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• 2017

Considering the advent of the Fourth Industrial Revolution, this study examines the changes and influences of intelligent information technology and the role of consumer education in the context of consumption life. The purpose of this study is to provide a theoretical foundation to effectively respond to the future consumption society as an independent consumer by enhancing the understanding of the Fourth Industrial Revolution in terms of consumption life. First, in terms of changes in the consumption paradigm in the Fourth Industrial Revolution, production and consumption are converged by being shared through a comprehensive connection platform in real time. Regarding the meaning of consumption, mental experience is being emphasized; moreover, usage and sharing, rather than ownership, are being highlighted. In terms of major changes in consumption life, the emergence of a more convenient smart consumption life and the possibility of personalized consumption optimized for individual demand are anticipated. Moreover, sustainable eco-friendly consumption is expected to increase further, and rapidly changing consumption trends will experience accelerated progress in consumer-centered changes. Next, the predicted problems in consumption life in the Fourth Industrial Revolution include unequal consumption due to intelligent information technology power center and the use and management of personal information data. Furthermore, ethical concerns related to the introduction of new technologies will become prominent, eventually resulting in issues concerning consumption satisfaction. To effectively respond to these new paradigm changes, consumer education should be value-centered. Ethical aspects of consumption should be considered, and consumption life should include trust and mutual cooperation. Furthermore, consumer education should facilitate creative convergence.

• Journal of Korean Society of Forest Science
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• v.90 no.6
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• pp.781-787
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• 2001

The spread rate of forest fire was analyzed on Samcheok forest fire that broke out on April 7, 2000 in Kunduck-Myun, Samcheok-City, Kangwon-Province and lasted for about 9 days. The spatial database including topography, overstory species distribution, micro-climate, daily fire front lines for the area was built using GIS and the daily spread pattern was investigated to determine a multiple regression equation to estimate forest fire spread rate. The results of the investigation showed that, on the first day, the forest fire spreaded out extremely fast up to 12.3m/min at about 10 a.m. until noon. After that, the forest fire spread rate fluctuated and slowed down as low as below 1m/min and quenched on April 15. The daily area-based spread rate along the fire spread line got to the peak of about 5,700ha on April 11, of which spread rates were recorded as 2.84m/min in the first half and 1.10m/min in the second half. Also, it was found that slope aspect, wind velocity and % area distribution of Pinus densiflora are the major factors affecting the spread rate of forest fire in this area.