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Serological and Histological Changes after Interferon Alfa Therapy in Children with Chronic Hepatitis B (소아 만성 B형 간염의 Interferon Alfa 치료 후 혈청학적, 조직학적 소견의 변화)

  • Ko, Jae-Sung;Chung, Ju-Young;Jang, Ja-Joon;Seo, Jeong-Kee
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.3 no.1
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    • pp.56-62
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    • 2000
  • Purpose: The aim of this study was to evaluate the efficacy and histologic changes of interferon-alfa therapy on chronic hepatitis B virus infection in children. Patients and Methods: Thirty five children aged 3~16 years who were seropositive for HBV DNA, HBsAg and HBeAg were enrolled. Interferon-alfa 2a ($3.4\;MU/m^2$) were given for 6 months. Serologic markers of viral replication was evaluated 1 year after therapy. Post treatment liver biopsy was performed in 18 patients who showed serologic response. Results: Serum HBeAg and viral DNA became negative in 22 (63%) of treated children at 12 months after therapy. Serum aminotransferase levels normalized in all of the responders and HBsAg became negative in one responder. Horizontal transmission, serum aminotransferase levels more than twice normal, and active inflammation on liver biopsy were predictive factors for response to interferon therapy. Periportal piecemeal necrosis, lobular activity, portal inflammation, fibrosis, and total histologic activity index were reduced in responders. Conclusion: In children with chronic hepatitis B, interferon alfa promotes loss of viral replication and improves aminotransferase. Serologic response is associated with improvement in hepatic histology.

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Development and Evaluation of a Left-Turn Actuated Traffic Signal Control Strategy using Image Detectors (영상검지기를 이용한 좌회전 감응식 신호제어전략 개발)

  • Eun, Ji-Hye;O, Yeong-Tae;Yun, Il-Su;Lee, Cheol-Gi;Kim, Nam-Seon;Han, Ung-Gu
    • Journal of Korean Society of Transportation
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    • v.29 no.2
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    • pp.111-121
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    • 2011
  • This paper discusses a method for optimizing the semi-actuated traffic signal control system by adjusting the initial interval according to the number of vehicles waiting for the green light in the actuated phase. We also present a Left-Turn actuated traffic signal control strategy that examines the vehicular noise in the detection area and determines the phase extension and the gap-out. In order to detect the vehicles in real-time, an image detector's Video Image Tracking technology was adopted. A 'Zone in Zone'method was implemented, and the image detection area is segmented into three zones: 1) Zone1 for verifying a vehicles obligatory presence, 2) Zone2 for counting the standby vehicles, and 3) Zone3 for examining the number of vehicles that have passed. The on-site assessment of the Left Turn Actuated Control is carried out using CORSIM, and the results show that the Control Delay decreased by 23.10%, 15.06%, and 4.34% compared to the delays resulted from pre-timed control, semi-actuated control-1 and semi-actuated control-2 traffic signal control systems respectively. The Queue Time also decreased by 36.24%, 20.10% and the Total Time by 14.36%, 7.02% for the same scenario. Which clearly demonstrates the operational efficiency. A sensitivity analysis reveals that the improvement from the propose traffic control strategy tends to increase as the through traffic volume reaches a saturated condition and the left-turn traffic volume decreases.

The Relationship between Bodyguard Leisure Types and Attitude toward Leisure (경호.경비요원의 여가 유형과 여가 태도의 관계)

  • Jung, Joo-Sub;Park, Jeong-Hun
    • Korean Security Journal
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    • no.31
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    • pp.101-123
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    • 2012
  • The 5 day workweek has become widespread, and more recently, the 40 hour workweek is planned to be implemented to the Korean industry by the government by 2012. It is possible that in the future, we may begin to complain about too much leisure, rather than too much work. There is a need then, for types options in leisure activity, brought about by personal choices and interests. The use of leisure time is a very personal matter. It is deeply related to types with the quality of life. Bagozzi (1981) developed a model discerning among attitude, intention and activity, that attitude affects behavioral intention, and behavioral intention affects activity. So, as behavioral activity has a deep relationship to behavioral intention, participation intention according to leisure types leads to participation in leisure activity. Sports activity and hobby and cultural activity appear to have high participation and it seems that this is reflected in behavioral attitude. Among the types of leisure satisfaction, sport activity satisfaction is associated with a more positive attitude to leisure than other types. With respect to background variables for attitude toward leisure according to leisure satisfaction, the biggest differences in attitude toward leisure were associated with sports activity.

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An Integrated Processing Method for Image and Sensing Data Based on Location in Mobile Sensor Networks (이동 센서 네트워크에서 위치 기반의 동영상 및 센싱 데이터 통합 처리 방안)

  • Ko, Minjung;Jung, Juyoung;Boo, Junpil;Kim, Dohyun
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.8 no.5
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    • pp.65-71
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    • 2008
  • Recently, the research is progressing on the SWE(Sensor Web Enablement) platform of OGC(Open Geospatial Consortium) to provide the sensing data and moving pictures collected in a sensor network through the Internet Web. However, existed research does not deal with moving objects like cars, trains, ships, and person. Therefore, we present a method to deal with integrated sensing data collected by GPS device, sensor network, and image devices. Also, this paper proposes an integrated processing method for image and sensing data based on location in mobile sensor networks. Additionally, according to proposed methods, we design and implement the combine adapter. This combine adapter receives a contexts data, and provides the common interface included parsing, queueing, creating unified message function. We verity the proposed method which deal with the integrated sensing data based on combine adapter efficiently. Therefore, the research is expected to help the development of a various context information service based on location in future.

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A Study of Intravenous Sedation in Dankook University Dental Hospital (단국대학교 치과대학 부속치과병원에서 시행된 정주진정에 대한 연구)

  • O, Jeong Eun;Kim, Jong-Su;Kim, Seung-Oh
    • Journal of The Korean Dental Society of Anesthesiology
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    • v.13 no.1
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    • pp.1-7
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    • 2013
  • Background: Intravenous sedation is effective for dental patients who are anxious. Recently, target-controlled infusion (TCI) has begun to be used widely to administer and titrate propofol and remifentanil during sedation. To investigate the effect and safety of the pharmacologic agents used in anesthetic department, we performed a retrospective study. Methods: Retrospective study of a series of dental procedure under intravenous sedation performed in department of anesthesiology in Dental Hospital of Dankook University was carried out with propofol or propofol/remifentanil between January and August 2011 and January and April 2012. All patients received oxygen by nasal cannula. The average propofol and remifentanil target was 0.5 ${\mu}g/ml$ and 1.0 ng/ml, respectively using a TCI pump. The average peripheral oxygen saturation ($SpO_2$), heart rate, blood pressure, respiratory rate, nasal end-tidal $CO_2$ were recorded at 5-10 minute intervals. The age, gender, weight, procedure and sedation time, type of procedure were also recorded. Results: We included 22 cases of 19 adults (group A) and 6 cases of children (group B). In group A, 4 patients received propofol (group A-P), and 15 patients received propofol with remifentanil (group A-PR). In group B, 6 patients received propofol only. The mean age of group A was 41.1 years old and that of group B was 9.5 years old. No clinically significant complications were noted. There were no case of de-saturation <90%. The median respiratory rate was 13.1 (range 6 to 36) in group A and 19 (range 13 to 25) in group B. The median end tidal $CO_2$ was 36.7 mmHg(range 8 mmHg to 56 mmHg) in group A and 41.7 mmHg (range 30 mmHg to 53 mmHg) in group B. Conclusions: Based on our results, dental sedation using propofol/remifentanil in adult and propofol in children with TCI pump seems to appear as a safe and effective procedure while performing dental procedure.

Resident관 Cognitions and Attitudes about Urban Development Policy: A Case of Sunchon City (지방도시의 발전정책에 관한 주민의 인식과 태도: 전남 순천시를 사례로)

  • 이정록
    • Journal of the Economic Geographical Society of Korea
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    • v.4 no.2
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    • pp.23-35
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    • 2001
  • Resident's attitude and evaluation about local or urban development policies is a major factor in the process of the regional and urban 1)tanning and its practices. Therefore there are numerous studies pointing to analysis about the evaluation of the urban development policies. The purpose of this paper is concerned on the residents'cognitions, attitudes and evaluation about of urban development policy of Sunchon City in South Korea. Research area, Suncgon city, has been served as a central place of eastern Chollanamdo since 1920 and now functions as economic and commercial leading city of Kwangyang-bay area. In addition, Sunchon city is fastly growned with the influence of national development policy including the establishment of major industrial estates and the construction of container port in Kwangyang-bay area. In the overall cognition and evaluation about the quality of life of Sunchon city, most people are satisfied with the quality of life of urban living comparing with near cities such as Kwangyang and Yosu city. In particular, the level of satisfaction about education, transportation, natural environment are relatively higher than economic condition and living facilities. Most of residents have positive attitude and evaluation about the image of future urban development, and prefer to culture and education city in urban function of Sunchon city. Therefore, in order to function as a central city of Kwangyang-bay area. Sunchon city have to adopt new urban development policy including such as reconstruction of urban spatial structure, strengthening of culture and education functions, and the related facilities, restructuring of regional industrial structure. and expansion of commercial and shopping facilities.

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Stylized Specular Reflections Using Projective Textures based on Principal Curvature Analysis (주곡률 해석 기반의 투영 텍스처를 이용한 스타일 반사 효과)

  • Lee, Hwan-Jik;Choi, Jung-Ju
    • Journal of the HCI Society of Korea
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    • v.1 no.1
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    • pp.37-44
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    • 2006
  • Specular reflections provide the visual feedback that describes the material type of an object, its local shape, and lighting environment. In photorealistic rendering, there have been a number of research available to render specular reflections effectively based on a local reflection model. In traditional cel animations and cartoons, specular reflections plays important role in representing artistic intentions for an object and its related environment reflections, so the shapes of highlights are quite stylistic. In this paper, we present a method to render and control stylized specular reflections using projective textures based on principal curvature analysis. Specifying a texture as a pattern of a highlight and projecting the texture on the specular region of a given 3D model, we can obtain a stylized representation of specular reflections. For a given polygonal model, a view point, and a light source, we first find the maximum specular intensity point, and then locate the texture projector along the line parallel to the normal vector and passing through the point. The orientation of the projector is determined by the principal directions at the point. Finally, the size of the projection frustum is determined by the principal curvatures corresponding to the principal directions. The proposed method can control the position, orientation, and size of the specular reflection efficiently by translating the projector along the principal directions, rotating the projector about the normal vector, and scaling the principal curvatures, respectively. The method is be applicable to real-time applications such as cartoon style 3D games. We implement the method by Microsoft DirectX 9.0c SDK and programmable vertex/pixel shaders on Nvidia GeForce FX 7800 graphics subsystems. According to our experimental results, we can render and control the stylized specular reflections for a 3D model of several ten thousands of triangles in real-time.

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A Study on Adolescents' Ethical Consumption Education Experience and Ethical Consumption Behavior (청소년의 윤리적 소비 교육 경험과 윤리적 소비행동에 관한 연구)

  • Jung, Joo-Won
    • Journal of Korean Home Economics Education Association
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    • v.24 no.3
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    • pp.191-208
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    • 2012
  • The purpose of this study was to explore a plan for maximizing effectiveness of adolescents' ethical consumption education. The ethical consumption education experience and the ethical consumption behavior in home, school and society were examined targeting 587 middle and high school students. As a result of research, first, adolescents' ethical consumption education experiences were indicated not to be mostly high. In the sphere of ethical consumption behavior, the ethical consumption education for the future generation of centering on green consumption was being much performed. Second, the students are much facing ethical consumption through participating in event and voluntary-service activity as for school program and through participating in flea market as for social program. And the tendency was being shown that has high contact frequency in ethical consumption education through internet. Third, the adolescent consumers' ethical consumption behavior level was not high as a whole. Thus, it could be known that the ethical consumption education is needed continuously. Especially, the education of the ethical consumption for current generation is further demanded. Fourth, the factors of having influence upon adolescent consumers' ethical consumption behavior were indicated that the more ethical consumption behavior is shown in more taking home consumer education and school consumer education in case of women and in the lower school year as for school year. In this way, the importance of ethical consumption education in home, school and society is indicated. Thus, there will be a need of being developed the educational method and the educational contents that are connected with real life so that adolescents themselves can acquire through experience by being linked mutually.

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Effect of Career Experiential Learning and Parental Support on Career Maturity of High School Students (고등학생의 진로체험 유형과 부모지지가 진로성숙도에 미치는 영향)

  • Jung, Joowon
    • Journal of Korean Home Economics Education Association
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    • v.28 no.4
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    • pp.139-158
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    • 2016
  • The purpose of this study was to explore the effects of career experiential learning and parental support on career maturity of high school students. The number of subjects for this study was 290 high school students. The results are as follows. First, the effects of attitude in career maturity were higher for students with communication, field trip and visiting, and field experience in career experiential learning. However, career planning did not have any correlation with field experience types of attitude in career maturity. The effect of competency in career maturity was positively correlated with student experience with theory, communication, and field trip and visiting in career experiential learning. Second, parental support showed a significant positive correlation with all factors of career maturity. Third, results identify career maturity impacts on career experiential learning. The types of communication as well as field trip and visiting significantly affected all components of career maturity. The type of theory was a factor affecting competency. In addition, the results reveal the impact of parental support on the career maturity. Emotional support had a significant influence on all factors for career maturity, except for career exploration. Informative support was found to have a significant influence on career planning, career independency and career exploration. Financial support had a significant influence on occupational attitude, career independency and career exploration.

Characteristics of MHEMT Devices Having T-Shaped Gate Structure for W-Band MMIC (W-Band MMIC를 위한 T-형태 게이트 구조를 갖는 MHMET 소자 특성)

  • Lee, Jong-Min;Min, Byoung-Gue;Chang, Sung-Jae;Chang, Woo-Jin;Yoon, Hyung Sup;Jung, Hyun-Wook;Kim, Seong-Il;Kang, Dong Min;Kim, Wansik;Jung, Jooyong;Kim, Jongpil;Seo, Mihui;Kim, Sosu
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.33 no.2
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    • pp.99-104
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    • 2020
  • In this study, we fabricated a metamorphic high-electron-mobility transistor (mHEMT) device with a T-type gate structure for the implementation of W-band monolithic microwave integrated circuits (MMICs) and investigated its characteristics. To fabricate the mHEMT device, a recess process for etching of its Schottky layer was applied before gate metal deposition, and an e-beam lithography using a triple photoresist film for the T-gate structure was employed. We measured DC and RF characteristics of the fabricated device to verify the characteristics that can be used in W-band MMIC design. The mHEMT device exhibited DC characteristics such as a drain current density of 747 mA/mm, maximum transconductance of 1.354 S/mm, and pinch-off voltage of -0.42 V. Concerning the frequency characteristics, the device showed a cutoff frequency of 215 GHz and maximum oscillation frequency of 260 GHz, which provide sufficient performance for W-band MMIC design and fabrication. In addition, active and passive modeling was performed and its accuracy was evaluated by comparing the measured results. The developed mHEMT and device models could be used for the fabrication of W-band MMICs.