• Title/Summary/Keyword: 정신약물학

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Older Adults' Self-reported Difficulty in Understanding and Utilizing Health Information (노인의 자가 보고에 따른 의료정보 이해 및 활용수준)

  • Kim, Su Hyun
    • 한국노년학
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    • v.30 no.4
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    • pp.1281-1292
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    • 2010
  • This study was performed to identify older adults' self-reported difficulties in understanding and utilizing health information and their relationships with health status and to investigate the differences between age groups and among education levels. Data were collected from July 1 to August 31 in 2007 from older adults in senior centers located in Daegu, Kyungpook, and Busan area. A total of 103 subjects participated in the study. The level of understanding health information in older adults was 50 on average (possible score 15-75). The most difficult items to understand were patient educational materials, written information provided by health care providers, and medical forms. The lower level of difficulty in utilizing health information was associated with better physical and mental health status. There were differences in their self-reported difficulties between the young-old and the old-old as well as among different education levels. Health care providers may need to tailor educational materials and medical forms to the cognitive ability of older adults under the consideration of their age and education levels.

Clinical Characteristics, Drug Adherence to Antipsychotics and Medical Use Trends in Patients First Diagnosed with Psychotic Disorder: A Preliminary Study (정신병적 장애로 첫 내원한 환자들의 임상 특징과 투약 순응도 및 의료 이용 추이: 예비 연구)

  • Heo, Jung Un;Kim, Dong Wook;Oh, Seung-Taek;Choi, Won-Jung;Park, Jaesub
    • Korean Journal of Schizophrenia Research
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    • v.22 no.2
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    • pp.42-50
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    • 2019
  • Objectives: In this preliminary study, we investigated the clinical characteristics of patients who were first diagnosed with psychotic disorder and explored the impact of the adherence to antipsychotics on long-term medical use. Methods: All national health insurance claims related to psychotic disorders including gender, age, income, and drug compliance, from January 1, 2008 to December 31, 2015, were examined. With trend test using Medication Possession Ratio (MPR), we compared the medical use between the compliant group (MRP≥0.8) and the comparative non-compliant group (0.2≤MPR<0.8). Results: Among 28,095 participants in total, 16,239 patients (57.8%) were diagnosed as schizophrenia; the 30s were the most common (n=7,151, 25.5%). Drug compliance was generally low regardless of the diagnosis and was the lowest among 20s with the 40-60% range of income. The compliant group showed lower psychiatric and medical use than the comparative group in the following years (p<0.0001). Conclusion: These findings suggest that patients in the 20s and 30s with the 40-60% range of income, who are diagnosed with schizophrenia at the first psychiatric visit, may need more clinical and political attention. The results also emphasize the importance of initial drug adherence to antipsychotics in reducing long-term psychiatric costs.

The Bibiographical Investigation of effect of Acorus gramineus Soland (석창포의 약리(藥理)에 대한 문헌적(文獻的) 고찰(考察))

  • Jung, Kuk-yung;Kho, Byung-hee;Song, Il-byung
    • Journal of Sasang Constitutional Medicine
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    • v.11 no.1
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    • pp.241-252
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    • 1999
  • 1. Purpose and Method : We have many difficulty of using the existing medical Hurbs based on the theory of Em-Yang and the five elements, this is why we still do not explain the Sasang Constitutional medical Hurb Classification and do not have the Sasang Constitutional Pharmacology exactly, so we easily enter into a dispute and confusion. So through literary consideration about Acorus gramineus Soland. I try to objectify Sasang Constitutional Classification of Acorus gramineus Soland and the spirit of using Acorus gramineus Soland and common property of Sasang Constitutional Medical Hurb and try to find out a clue that search the effect of other Sasang Constitutional Medical Hurb. 2. Result : Qi(氣) and mi(味) of Acorus gramineus Soland have aroma and hot taste and have won Qi(溫氣), the using portion of Acorus gramineus Soland is root as medical Hurb. So Acorus gramineus Soland rise from Goonghacho(中下焦) to Sangcho(上焦) and divied impurity and purity and able to remove the turbidity Qi(氣)Ack(液) Acorus gramineus Soland have the effect of progressing the involution of Paeqi(肺氣) and divided impurity and purity of Qi(氣) and ack(液) and improve the fuction and structure of Tae-Em-ln. I think that the method of literay consideration on objectification of Sasang Constitution Pharmacology is of great value.

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The Bibiographical Investigation of effect of Clematis mandshurica Maxim (위령선(威靈仙)의 약리(藥理)에 대한 사상의학적(四象醫學的) 고찰(考察))

  • Jung, Kuk-yung;Song, Il-byung
    • Journal of Sasang Constitutional Medicine
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    • v.10 no.2
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    • pp.151-162
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    • 1998
  • Purpose and Method : We have many difficulty of using the existing medical Hurbs based on the theory of Yin-yang and the five elements, this is why we still do not explain the Sasang Constitutional medical Hurb Classification and do not have the Sasang Constitutional Pharmacology exactly, so we easily enter into a dispute and confusion. So through literary consideration about clematis mandshurica Maxim. I try to objectify Sasang Constitutional Clasification of Clematis mandshurica Maxim and the spirit of using Clematis mandshurica Maxim and common property of Sasang Constitutional Medical Hurb and try to find out a clue that search the effect of other Sasang Constitutional Medical Hurb. Result : Qi(氣) and mi(味) of Clematis mandshurica Maxim has bitter and hot taste and have won Qi(溫氣), the color is dark, the using portion of clematis mandshurica Maxim is root as medial Hurb. So Clematis mandshurica Maxim fall down from lung and divied impurity and purity and able to remove the symptom that dryness and fever is solidified like Magnoliae cortex(厚朴). Clematis mandshurica Maxim have the effect of awakening Jin-Qi(眞氣) of lung and divide impurity and purity of Qi(氣) and ack(液) and improve the fuction and structure of Taeumin(太陰人) I think that the method of literay consideration on objectification of Sasang Constitution Pharmacology is of great value.

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Analysis of variables Influenced on the Patterns of Antipsychotics Medication by Schizophrenic Out-patients : Using the Technique of Two Group Discriminant Function Analysis (외래 정신분열병 환자의 항정신병 약물복용 양상에 관한 연구 : -판별함수분석기법을 통한 결정변인 분석 -)

  • 김태경
    • Journal of Korean Academy of Nursing
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    • v.23 no.1
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    • pp.130-141
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    • 1993
  • This study was to find out variables influenced on the medication patterns (voluntary medication, in-voluntary medication) of antipsychotics taken by schizophrenic outpatients. Purposes of this study were to be identified that there was the significant difference between the group of voluntary medication and involuntary, and that which variables had infuence on outpsychotics medication. The sample consisted of 30 patients takeing their pills voluntary (voluntary medication group), and 15 patients involuntary(involuntary medication group) at a psychiatry hospital and a psychiatric unit of a The findings of the study are as follows : university hospital in Daegu. Data were collected from September to October, 1991 through interview using questionare about antipsychotics medication. Data were analyzed by the technique of two group discriminant function analysis using SPSS pc$^{+}$ 1) Discriminant function discriminating between voluntary medication and involuntary medication was significant at the level of 10% significance (sig.=.055, p〈.10) Hit-ratio was very high (91. 1%) 2) One of General variables, SEX, was significant of discriminating between two medication patterns at the level of 10% significance. 3) One of Family Environmental Variables, BROTH(a number of brother), were significant between two medication patterns. (p〈.10) 4) One of Therapeutic Environmental Variables, FAMHX, was significant between two medication patterns at the level of 10% significance. 5) One of Variables Related to Drug and Medication, NECESS, was significant between two medication patterns. (p〈.05) 6) Variables Related to Disease was not significant between two medication patterns.s.

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Insomnia in the Elderly (노인에서의 불면증)

  • Sohn, Chang-Ho
    • Sleep Medicine and Psychophysiology
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    • v.8 no.1
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    • pp.5-10
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    • 2001
  • The prevalence of insomnia and the degree of impairment due to insomnia is greater than in the of young. The cause for insomnia in the elderly are various factors among the elderly is known to be high including medical, psychiatric, drug issues, circadian rhythm changes, sleep disorders, and psychosocial. So the careful evaluation to find the cause of insomnia is needed for the eldery. Treatment options for insomnia include behavior modification and pharmacotherapy. Outcome data from previous studies indicate that behavioral approaches produce reliable and durable therapeutic benefits, as evidenced by improved sleep efficiency and continuity and enhanced satisfaction with sleep patterns. Treatment methods such as stimulus control and sleep restriction, which target maladaptive sleep habits, are especially beneficial for older insomniacs, whereas relaxation-based interventions aimed at decreasing arousal, produce more limited effects. Cognitive and educational interventions are instrumental in altering age-related dysfunctional beliefs and attitudes about sleep. The choice of hypnotics is based on matching the nature of the insomnia to the hypnotic agent. The ideal agent has rapid onset, duration of action that lasts through the night but no residual daytime effects, and no adverse effects. The key for the healthcare professional is finding the appropriate treatment or treatment combination, including behavioral modification and pharmacotherapy. When hypnotics are indicated, the most appropriate short-acting agent should be considered.

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Clinical Pharmacology of Psychotropic Agents in Pregnancy (임신시 향정신성 약물의 임상약리학)

  • Roh, Hyung-Keun
    • Korean Journal of Biological Psychiatry
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    • v.3 no.2
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    • pp.149-155
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    • 1996
  • Doctors who treat pregnant women ore usually cautious in writing their prescription for the drugs. The problem of which psychotropic medications ore sale during pregnancy seems to remain unsolved for many years. Although the rate of absorption is reduced due to a reduced rate of gastric emptying, the extent of absorption of drug is generally unchanged during pregnancy. Plasma volume and total body water increase during pregnancy. There is suggestion that drug metabolizing activity may be increased in pregnancy. Since the pregnancy increase the glomerular filtration rate significantly, drugs mainly eliminated by renal excretion will be cleared more quickly. Factors contributing to the potential teratogenecity of a drug include the type of compound, dose and duration of use, developmental stage of fetus at the time of exposure, and the effect of the drug on fetal pharmacokinetics. All major classes of psychotropic agents should be assumed to diffuse readily across the placenta to the fetus and to be present in some quantity in the breast milk. To decide when and how to start the drug treatment depends on an assessment of the risks related both with and without drug treatment of psychiatric disorders.

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Effectiveness of the Self-care Education for the Medication and Symptoms Management on the Psychiatric Patients' Quality of life (약물 및 증상관리에 대한 자가간호교육이 정신질환자의 삶의 질에 미치는 효과)

  • Son Kyung-Hee
    • The Journal of Korean Academic Society of Nursing Education
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    • v.5 no.2
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    • pp.300-314
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    • 1999
  • This study is an attempt to evaluate the effect of the medication and symptoms self-care education on the psychiatric patients' quality of life. This exploratory study was designed to a quasi-experiment of pretest-postest with a non equivalent control group. Subjects of 40 patients who were discharged from a mental hospital in Pusan were selected to be experiment and control group, with each group consisting of 20. The research period was from March, 6 to May, 29, 1999 and the pre-post test was given before and after implementing MSSE to the both experiment and control group. The results finding were summarized as follows ; 1. subjects who attended self-care education scored significantly higher than control group in quality of life.(Z=-2.06, P=0.034) 2. Those who were in the experiment group reported more significant higher scores than control group in item of quality of life, living situation(A=-2.62 P=0.012), relations with spouse (Z=-2.31 P=0.038) and children (Z=3.37, P=0.008), fear (Z=-1 95, P=0.049) and anger(Z=-2.07 P=0.041), work functioning (Z=-2.34, P=0.021), environmental adjustment. (Z=-2.05, P=0.039)

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Frontotemporal Dementia (전두측두엽 치매)

  • Jun, Byoung Sun;Park, Joon Hyuk
    • Korean Journal of Biological Psychiatry
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    • v.23 no.3
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    • pp.69-79
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    • 2016
  • Frontotemporal dementia (FTD) is a degenerative disease characterized by the selective frontal and temporal lobe atrophy, and progressive deficits in behavior, executive function, or language. The prevalence and incidence of FTD are 15-22/100000 and 2.7-4.1/100000, respectively, in midlife. Hereditary is an important risk factor for FTD. Although there is some controversy regarding the further syndromatic subdivision of the different types of FTD, FTD is clinically classified into behavioral variant of frontotemporal dementia, semantic dementia and progressive nonfluent aphasia. FTD can be misdiagnosed as many psychiatric disorders because of similarity of the prominent behavioral features. Advances in clinical, imaging, and molecular characterization have increased the accuracy of FTD diagnosis, thus developing for the accurate differentiation of these syndromes from psychiatric disorders. We also discuss about therapeutic strategies for symptom management of FTD. Medications such as serotonin reuptake inhibitors, antipsychotics, and other novel treatments have been used in FTD with various rates of success. Further advanced research should be directed at understanding and developing new diagnostic and therapeutic modalities to improve the FTD patients' prognosis and quality of life.

Can We Predict Treatment Response in Major Depression? (주요우울증에서 치료반응을 예측할 수 있는가?)

  • Ko, Young Hoon;Kim, Yong Ku
    • Korean Journal of Biological Psychiatry
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    • v.11 no.2
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    • pp.77-87
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    • 2004
  • Due to the high population prevalence of major depression and the strong emphasis on pharmacotherapy for this disorder, antidepressants are among the most frequently prescribed pharmacological agents. But the clinicians are still unable to predict accurately the response of their depressed patients to medication. This article reviews the biological predictors of treatment response including monoamine, neuroendocrine, pharmacogenetic, and psychophysiologic markers. The biological predictors of response, despite some interesting leads that may in the long term be of considerable importance, are not yet sufficiently established to be of routine clinical usefulness. Many of the predictive factors explored in this article are examples of mediators and moderators that affect outcomes. Each one alone may not provide definitive answers for predicting response to treatment, but each must be taken into account at the outset of treatment. It is clear that treatments must be individualized for each patient. It would be necessary to develop the algorithm in order to predict the responsiveness of antidepressant treatment with integration of the results from the previous studies.

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