• 제목/요약/키워드: 정상노화

Search Result 188, Processing Time 0.024 seconds

Effects of Astragali Radix Herbal Acupuncture Extracts on the Collagenase Activity and Procollagen Synthesis in HS68 Human Fibroblasts and Tyrosinase Activity (황기 약침액의 사람 섬유아 세포에서 Collagen 생성과 Tyrosinage 활성에 미치는 영향)

  • Kim, Jee-Hyun;Jung, Tae-Young;Lee, Bong-Hyo;Lee, Yun-Kyu;Kim, Jae-Su;Lee, Kyung-Min;Lim, Seong-Chul
    • Journal of Acupuncture Research
    • /
    • v.28 no.3
    • /
    • pp.13-20
    • /
    • 2011
  • 목적 : 본 연구는 황기약침액의 collagen 대사과정과 tyrosinage 활성에 대한 효과를 관찰하여 항노화 약침소재로의 개발 가능성을 알아보고자 계획되었다. 방법 : 황기 약침액이 사람 정상 섬유아세포 HS68에 UVB 조사 후 type I procollagen의 생산량 회복과 collagenage 활성에 미치는 효과를 ELISA법을 이용하여 측정하였다. 황기약침액의 tyrosinage 활성도에 미치는 영향을 측정하였다. 결과 : 황기 약침액은 사람 섬유아세포 HS68 실험에서 UVB 조사로 감소된 type I procollagen생성을 회복시키고, 통계적으로 유의하게 collagenage 활성을 억제하는 것을 관찰하였고 tyrosinage 활성을 통계적으로 유의하게 억제하지만, L-DOPA 산화는 억제하는 경향이 있는 것을 관찰하였다. 결론 : 본 연구 결과에 의하면, 황기약침액은 collagenage 활성을 억제하고, tyrosinage 활성을 억제하므로 주름개선과 미백효과가 있어 미용약침 소재로 개발가능성이 있을 것으로 사료된다.

Dip Estimation for Overhead Transmission Conductor using Catenary Angle (카테너리 각도를 이용한 가공송전도체의 이도 추정)

  • Kim, Sung-Duck;Sohn, Hong-Kwan;Jang, Tae-In
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
    • /
    • v.21 no.5
    • /
    • pp.112-119
    • /
    • 2007
  • Under normal operating condition, the conductor of overhead transmission line could be always hold it's clearance within the safety margin that is specified in the line design guide of power company. Hence it may be very important to measure/or monitor the dip of the conductor, when building a new line, re-tensioning for an aged conductor, or monitoring dynamic line rating to maximize power capability. In this paper, we suggest a new method to estimate the dip and tension by catenary angle of the conductor. Since most conductors in overhead transmission lines show typical catenary curves, it can be uniquely determined the catenary curve for the conductor from the catenary angle at tower. Based on the catenary curve, the dip or horizontal tension can be easily estimated. Through some simulation and simple experimental results, it is verified that the suggested method can be effectively applied to measure/or monitor conductor dips and tensions in the overhead transmission lines.

Gender differences in age-related decline of regional cerebral glucose metabolism: implications for the gender differences in frontal function (연령 증가에 따른 전두엽 포도당대사 저하의 남녀 차이)

  • Lee, Eun-Ju;Cho, Sang-Soo;Yun, Eun-Jin;Kim, Yu-Kyeong;Lee, Won-Woo;Kim, Sang-Eun
    • Proceedings of the Korean Society for Cognitive Science Conference
    • /
    • 2005.05a
    • /
    • pp.212-215
    • /
    • 2005
  • 연령의 증가에 따른 신경원의 활성화도 변화는 기억 및 집행기능 등의 인지기능에 영향을 미치는 것으로 알려져 왔다. 그러나 어떠한 뇌 영역의 기능적 저하가 연령증가에 따라 남자와 여자에서 차별적으로 인지기능의 변화를 가져오는지에 대해서는 거의 알려진 바가 없다. F-18 FDG PET을 이용하여 78명의 정상 성인 남녀를 대상으로 뇌 포도당 대사량을 조사하였다. 남녀가 공통적으로 연령증가에 따라 뇌 포도당 대사량의 저하를 보이는 영역은frontal lobe과 left insula, right anterior cingulate gyrus, bilateral caudate body, thalamus. right corpus callosum 이었다. 여성의 경우 남성과 달리 추가적으로 right caudate와 bilaterial thalamus에서 연령과 뇌 포도당대사량 간에 부적 상관을 보이고 있었다(P < 0.001 uncorrected). 남녀 모두에서 연령이 증가하면서 포도당 대사 저하를 보이는 right inferior frontal gyrus는 여자에게서만 포도당대사 감소비율이 유의하게 컸다. 남녀에서 보이는 이러한 노화 과정 동안의 뇌 포도당 대사의 저하율의 차이가 여성과 남성의 연령증가에 따른 인지적 기능의 차별적 저하에 대한 설명을 제시할 수 있을 것이라 생각한다.

  • PDF

The Evaluation Indexes' Selection of the Degree of Danger from Big and Old Trees (노거수 위험도 평가지표 선정 연구)

  • Xia, Tian-Tian;Kang, Tai-Ho
    • Journal of the Korean Institute of Landscape Architecture
    • /
    • v.45 no.4
    • /
    • pp.54-61
    • /
    • 2017
  • Strengthening the protection and management of very old trees is an important aspect of urban site preservation, urban design and construction. Rating various danger factors to evaluate the degree of danger posed can help to create the correct protective countermeasures. In order to develop the danger evaluation index, this study performed four round surveys by using the Delphi method and collected opinions from experts in related fields. Necessary indexes were fully added in the first and second round while the indexes falling beyond the guidelines were deleted. From the final analysis results, five areas derived a total of forty-one indicators to create a degree of danger index from vigour status, growth and development status, diseases and insect pests, soil status, and management status. The degree of danger evaluation index can provide basic data for the protection of very old trees.

Selction of Useful Chemicals Reducing Soybean -Sprout Rot (콩나물 부패경감에 유용한 약제 선발)

  • 박의호;최연식
    • KOREAN JOURNAL OF CROP SCIENCE
    • /
    • v.40 no.4
    • /
    • pp.487-493
    • /
    • 1995
  • This study was carried out to select useful chemicals to control pathogens inciting soybean-sprout rot. Pathogen strains were isolated from decaying soybean seedlings. The isolated strains were identified as Pseudomonas spp. (Pse. strains) through microbiological test, however, no rot-inciting fungus was isolated. Eight food additives were tested with different concentrations in controlling pathogens and harmfulness. Five chemicals(over 5% cone.) including sodium hypochlorite apparently inhibited the growth of Pse. strains on media plate, however, sodium hypochlorite was discarded due to its severe germination inhibition. Propionic acid and acetic acid inhibited the growth of Pse. strains more effectively than calcium propionate and sodium propionate relatively. As no harmful effect on seed germination and no growth retard of soybean sprouts were observed by those chemicals with lower concentration(0.5∼1.0%), these chemicals were considered to be applicable to sprout rot control judged by the effectiveness and permissible concentration as food additives.

  • PDF

Effect of BA and NAA on Adventitious Bud Induction From In Vitro Germinant Eucalyptus pellita (Eucalyptus pellita 기내발아묘의 부정아 유도에 미치는 BA 및 NAA 효과)

  • Kim Ji-Ah;Moon Heung-Kyu;Kang Ho-Duck
    • Journal of Plant Biotechnology
    • /
    • v.32 no.3
    • /
    • pp.201-207
    • /
    • 2005
  • This study was conducted to examine the effect of BA and NAA on adventitious bud induction from in vitro germinants E. pellita. The capacity of adventitious bud formation greatly depends on juvenility and explants origin; the more juvenile materials are the better ability to form adventitious buds even in in vitro raised plantlets. In case of in vitro germinants, 7 day old plantlets showed a better morphological response than did 14 day old ones in the induction of adventitious buds. The capacity to show morphological response was in decreasing order : cotyledons> petioles> roots. Ho adventitious buds formed when root segments were used as culture material. And optimum medium appeared to be MS + 0.5 mg/L BA and 0.2 mg/L NAA. Adventitious buds could be developed into multiple shoots and regenerated normal plantlets on DKW medium plus 0.2 mg/L BA and 0.01 mg/L NAA.

Effect of simulated Acid rain on Foliar Structural of Changes of Ginkgo biloba and Pinus thunbergii (은행나무와 곰솔에 처리된 인공산성비에 의한 잎의 형태변화)

  • 소웅영
    • Journal of Plant Biology
    • /
    • v.38 no.1
    • /
    • pp.79-86
    • /
    • 1995
  • Visible injury symptoms such as necrosis, chlorosis and premature senscence in the leaves of Ginkgo bloba and Pinus thunbergii treated with acid rain of pH 3.2 or below were observed. The epicuticular wax erosions were observed by SEM after exposure to acid rain of pH 2.4 and 3.2 in G. biloba and pH 4.0 below in P. thunbergii. The adaxial epidennal cells and sponge parenchyma cells were compressed, and those were distorted in the leaves of G. biloba treated with simulated acid rain of pH 3.2 or below. However, vascular tissue was intact. With increase of acidity, mesophyll cells were smaller than those of control while intercellular space in mesophyU was increased. In P. thunbergii, sponge parenchyma cells and vascular tissue except epidennis were distorted after exposure to acid rain of pH 2.4. The size change of stomata in foliar injury was not observed, but the stomatal index and size of stomatal aperture in leaves treated with acid rain increased. The stomata of injured leaf were opened in both species examined.amined.

  • PDF

Correlations between Sensory Processing Abilities and Safe Driving Behavior in Older Adults (노인의 감각처리능력과 안전운전행동에 관한 상관성 연구)

  • Kim, Hee-Dong;Ko, Hyo-Eun;Jang, Yeon-Sik;Cho, Nam-Ju;Baek, Ji-Young
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.15 no.5
    • /
    • pp.2743-2748
    • /
    • 2014
  • The research was conducted to understand the correlation between sensory processing ability and safe driving behavior of over 65. Questionnaires regarding sensory processing ability and safe driving behavior were given to 31 people who are in their 65 or over and Pearson Correlation Analysis was carried out on the survey. The result of the research indicates that there is interrelationship between total score of sensory processing ability and safe driving behavior, and sub factors. According to the findings, over 65 showed certain difficulties in sensory processing ability and safe driving behavior due to aging. Therefore, it would be necessary to evaluate their driving behavior and arbitrate appropriate operation therapy.

Review of Balance in Elderly by Vestivulo-ocular Reflex (안뜰눈반사를 통한 노인 균형 연구)

  • Baek, Su-Jeong
    • The Journal of Korean society of community based occupational therapy
    • /
    • v.8 no.3
    • /
    • pp.91-106
    • /
    • 2018
  • The purpose of this paper is to review vestibulo-ocular reflex and vestibular rehabilitation for balace problem in elderly. Falling is a common problem associated with aging. Falling and the resulting consequences constitutes one of the most common and serious problems. Balance deficits are one of the top risk factors for falling. Three systems(visual, vestibular and somatosensory) need to be integrated and used to coordinate and control balance. During normal ambulation and head movement, the vestibulo-ocular reflex(VOR) stabilizes gaze, and helps to keep the image of the retina. There is a direct association between deficits in VOR and falls. Older adults have a decreased ability to enhance and suppress the VOR. Vestibular rehabilitation(VR) is an exercise-based group of approaches that began with the aim of central nervous system compensation. VR restores VOR gain and reduces error using repetitive movements of the head and eyes. Many researches showd balance and gait tests were superior in the VR group. It is considered this article helps to prevent elderly falling with vestibular rehabilitation.

Study on Evaluation of Internal Hair Porosity using Optical Microscopy and Improvement of Hair Luster through Internal Hair Density (광학 현미경을 이용한 모발 내부 다공성 평가 및 모발 내부 밀도 증가를 통한 윤기 증가 연구)

  • Hyun-Sub Park;Seong Kil Son;Nae-Gyu Kang;Ik Hyun Lee
    • Journal of the Society of Cosmetic Scientists of Korea
    • /
    • v.49 no.3
    • /
    • pp.225-230
    • /
    • 2023
  • In this study, the porous structure inside the hair were observed using an optical microscope without damaging the hair, and the porosity inside the hair was quantitatively expressed using the results. Experiments were conducted on the effect of the decrease in density inside the hair on the bending and tensile properties of the hair, and experiments on endogenous and extrinsic factors were conducted to find out the causes of the decrease in density inside the hair. As for the endogenous factor, the porosity of gray hair, one of the representative symptoms of aging, was compared with normal hair. As for extrinsic factors, it was observed that the internal density of hair decreased by surfactant and heat, which are factors that can cause hair damage in daily life. In addition, we confirmed whether it is possible to increase the internal density and luster of the hair by using an amino acids and material that can prevent hair lipid predisposition.