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Retrospective Analysis of Patients Suffering from Dementia or Mild Cognitive Impairment Treated by Collaboration between Western and Korean Medicine (한양방 협진치료를 받은 치매와 경도인지장애 환자에 대한 후향적 의무기록 분석)

  • Lee, Go Eun;Cheong, Moon Joo;Lee, Sung Ik;Kim, Nam Kwen;Kim, Jinwon;Kang, Hyung Won
    • Journal of Oriental Neuropsychiatry
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    • v.29 no.2
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    • pp.111-119
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    • 2018
  • Objectives: To investigate the characteristics of patients diagnosed with dementia or mild cognitive impairment who are treated by means of a blend between Western and Korean medicine. Methods: We searched for outpatients with dementia or mild cognitive impairment by means of a collaboration between Western and Korean medicine from August 1, 2015, to July 31, 2017, through electronic medical records in Wonkwang Hospital. The records were retrospectively analyzed according to the patients' demographic and clinical characteristics, pathway of medical care, diagnostic tests, treatment, and medical expenses. Results: Thirteen patients were included in the analysis. Among them, six patients were diagnosed with mild cognitive impairment, five with dementia, Alzheimer's type, one patient with frontotemporal dementia, and one patient with unspecified dementia. Twelve of the thirteen patients were over 60 years of age. The number of pathways from the Dept. of Neurology to the Dept. of Neuropsychiatry of Korean Medicine was almost the same as the opposite pathway. The most used diagnostic test in Korean medicine was a neuropsychological test such as SNSB, MMSE and GDS. In Western medicine, hematology and neuroimaging were frequently used for patients. Acupuncture in Korean medicine and medication in Western medicine were the most frequently used. In Korean medicine, uncovered service costs were much higher than covered service costs,. whereas, in Western medicine, covered service costs were higher than uncovered service costs. Conclusions: This study describes the basic characteristics of dementia and mild cognitive impairment patients treated by a collaboration between Western and Korean medicine. Based on these results, a clinical pathway of the collaborative practice system between Western and Korean medicine for dementia patients needs to be developed.

A Study on Developing the Draft of International Standard for the Determination of Perchlorate in Soil Using Ion Chromatography (이온크로마토그래피를 이용한 토양 중 퍼클로레이트 정량에 관한 국제표준(안) 연구)

  • Choi, Cheon-il;Lee, Goon-taek;Park, Min-ki;Jeong, Moon-ju;Kim, Ji-yang;Kang, Ji-young;Ryu, Ji-young
    • Journal of Soil and Groundwater Environment
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    • v.20 no.6
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    • pp.55-61
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    • 2015
  • Based on the literature study for the determination of perchlorate in soil we chose the ion chromatography as a measurement method and decided to use 70 mM KOH as an eluent to avoid the interference derived from the co-elution of pyrophosphate (P2O74−), tripolyphosphate (P3O105−). Also we proposed to use air dried soil through 0.15 mm sieve and distilled water as an extractant. Under the these basic concepts, we carried out the experiments to set up the detail procedure like solid to liquid ratio (S/L ratio), extraction time, device for extraction and indicating factors for quality control (e.g. precision, accuracy, MDL, LOQ). In case of time and device for extraction, 5 hours of mechanical shaking or 1 hour of centrifugation showed better precision and accuracy than that of sonication for 1 hour According to these results, we proposed the extraction method combining 5 hours of mechanical shaking with 1 hour of centrifugation. From the aspect of S/L ratio, the ratio of 1/2 or 1/3 showed resonable precision and accuracy. In case of the ratio of 1/2, there would be some problems in the separation process when the proportion of fine particle is high. Therefore, we proposed the extraction ratio of solid to liquid as 1/3 instead of 1/2. With the consideration of cost effectiveness and soil salinity, we proposed the use of cartridge for removing the interfering anions like chloride, sulfate and carbonate in specific sample such as saline soil.

Expression of Nerve Growth Factor in Estradiol Valerate-induced Polycystic Ovary Syndrome (Estradiol valerate에 의해 유발되는 다낭성난소증후군의 Nerve Growth Factor 변화)

  • Kim, Se-Eun;Lim, Sung-Chul;Jeong, Moon-Jin;Choi, Baik-Dong;Kim, Seung-Hyun;Ko, A-Ra;Seo, Seung-Yong;Kang, Seong-Soo;Moon, Chang-Jong;Kim, Jong-Choon;Kim, Sung-Ho;Bae, Chun-Sik
    • Journal of Veterinary Clinics
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    • v.28 no.4
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    • pp.403-407
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    • 2011
  • A form of polycystic ovary (PCO) resembling some aspects of the human PCO syndrome (PCOS) can be induced in rats by a single injection of estradiol valerate (EV). An increase in sympathetic outflow to the ovary precedes, by several weeks, the appearance of cysts, suggesting the involvement of a neurogenic component in the pathology of this ovarian dysfunction. To test the hypotheses that the change in sympathetic tone is related to an augmented production of hippocampal and/or ovarian nerve growth factor (NGF), and that this abnormally elevated production of NGF contributes to the induction of PCOS induced by EV. The animals were sacrificed after PCOS induction and the ovaries and hippocampus were sectioned and compared to the normal control. The expression of NGF was measured by immunohistochemical staining and Western blot analysis in the ovaries and hippocampus. EV-induced PCOS showed significant increase of ovarian NGF expression. Immunohistochemical expression of NGF was confined to the follicular cells and interstitial cells. Hippocampal NGF expression was not significantly changed. In conclusion EV-induced PCOS was related to the ovarian sympathetic activation which was mediated by NGF.

The Results of Surgical Treatments in the Peripheral Nerve Injuries (말초신경 손상 후 수술적 치료에 대한 고찰)

  • Chung, Moon-Sang;Park, Jin-Soo;Seo, Joong-Bae;Park, Yong-Bum
    • Archives of Reconstructive Microsurgery
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    • v.5 no.1
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    • pp.121-127
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    • 1996
  • Peripheral nerve injury occurs mostly by trauma and is usually associated with fracture of bone and joint, muscular injury and tendon injury and it also evokes paralysis and anesthesia. When treatment of peripheral nerve injury is considered,, the modality of treatment is decided by the general condition of the patient, type of injury, associated injuries and the condition of wound. To get the maximum results, surgical treatment and reconstruction and rehabilitation should all go in hand-in-hand. From January 1985 to December 1994, we observed 61 patients that had operation without reconstruction due to peripheral nerve injury with a follow-up period of more than 1 year. Among the 61 patients, 44 were men(72%) and 17 were women(28%). Follow-up period was average 19 months. Age distribution was mostly in their twenties with a mean age of 28 years. Time interval of operation after injury was average 11 months. Trauma was the main cause of peripheral nerve injuries with a proportion of 87%. 31 patients had neurorrhaphy, in which case 14 patients had stay suture and 17 patients did not. 14 patients had nerve graft, and 16 patients had neurolysis. We used our scales to compare the results of surgery on the basis of British Research Council System. We gave scores to every sensory and motor scale to estimate functional improvement and emphasized on motor functional improvement. The total score = sensory score + ($2{\times}motor$ score). We considered 8-9 points as excellent, 6-7 points as good, 2-5 points as fair, 0-1 points as poor result. We considered excellent and good as much improved. Excellent and good results were obtained in 13 out of 14 neurorrhaphy with stay suture(93%), 12 out of 17 neurorrhaphy without stay suture(71%), 6 out of 14 nerve graft(43%), 12 out of 16 neurolysis(75%). Among the patients with neurorrhaphy done within 3 months, 11 out of 14(86%) showed improvement, but among the patients after 4 months 3 out of 17(76%) showed improvement. 84% of improvement was observed in the patients with time interval from injury to surgery within 3 months, and 64% in the patients with time interval after 4 months. In the aspect of age, 77% with the age below 20 years, 70% with the age between 21 and 30 years, 66% with the age above 31 years showed improvement. We conclude that considering degree of injury, time interval from injury and age with the adequate method of treatment, we can obtain good results from surgery.

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A Preliminary Study for Curriculum Building in Nursing (교육과정개발을 위한 학생측면의 기초연구 - 간호학과 학생의 자아개념과 교육자의 인식을 중심으로 -)

  • Jung Moon-Hee;Lim Nan-Young;Choi Sun-Ha;Do Keong-Jin
    • Journal of Korean Public Health Nursing
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    • v.4 no.2
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    • pp.35-57
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    • 1990
  • This study was conducted to provide information useful in developing a nursing curriculum. The sample consisted of 158 nursing students in Hanyang University and 34 faculty members who has taught them in their college & the practical area. Data were collected by using a structured questionnaire, which consisted of general characteristics of the students & their self-concept, teacher's perception of student's professional roles. The results are summarized as follows; 1. General characteristics of the students When the students applied for the university, they decided what they would specialized in. Because the motive of application for their major was simply based on their high school records, they were admitted to their university without previous knowledge of their major. The reason why they wanted to tranfer to another course after the admission was the same as above. The level of satisfaction of their major was the highest in Freshman, but in other grades the higher the;, grades were, the more they satisfied with their major and they had a better prospects about their speciality. 2. Self-concept in profermance for their major Self-concept in horne aspects was more positive perception than in social aspects & self control aspects. It resulted from tile fact that all students were females and the nursing uniqueness was based on the spirit of humanity & service. The students who had graduated from the high school in rural area wanted to tranfer to another course and taken counsel their personal problems with their parents had higher self-concept in horne aspects. As their grades were higher, the self-concept in social aspects bacame higher. The students who were satisfied with their major and took counsel their personal problems with their parents had more positive self - concept in social aspects. Self-concept in self control aspects was lower than other aspects. The students who didn't take counsel their problems with their parents, were burdened with their educational expenses and their curriculum had more negative self-concept in self control aspects. Therefore the university should be concerned about student's welfare and provide detailed orientation about their curriculum. 3. Teacher's perception about learner's professional role The role model of democratic group leader, role models for learners facilitator in a students' reach for knowledge and teaching based on soundly researched theory showed more positive perception than other factors. Their mean values were over 4. 32. The professionalism of allnurshing area, reinforcement with reinforcement for learning, nursing as part of the meaningful context of the whole showed nagative perception. Their mean values were below 3. 00. Therefore the nurse as a teacher should try to promote the locus of nursing profession and participate in their research actively.

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A Review on Stress and Coping Level at Dysmenorrhea Perceived by Middle School Girls in Seoul (월경곤란시 여자중학생이 지각하는 스트레스 및 그 대응에 관한 소고)

  • Jung Moon-Hee
    • Journal of Korean Public Health Nursing
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    • v.5 no.2
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    • pp.45-51
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    • 1991
  • The purpose of this study is to investigate the stress and coping level as a result of dysmenorrhea which was experienced by girls. For the collection of data, the girls from the 1st to the 3rd grade in middle school in Seoul were selected through a random sampling technique. The survey was conducted from the 1st. to the 14th of June, 1991 by the use of questionnaires made after a pilot study. The final subjects for analysis were restricted to only those who had experienced me~arche, the number of which totaled 1,131. The stress, coping level, and other variables, were tested and analysed by descriptive statistics (eg, frequency, percentage, mean and standard deviation), t-test, ANOVA and Pearson's correlation coefficients. The obtained results are summarized as follows. 1. The chronological start for menarche was at a mean age of 13.1 The respondents who had experienced menarche numbered $70.9\%$ of the 1st grades and $96.2\%$ of the 2nd grades in middle school, otherwise the starting age for menarche was in the 4th grade in primary school. 2. Their menstrual cycle and period were longer than adult's one. The number of students studied who had experienced dysmenorrhea during their menstrual cycle were 860, and 650 of those revealed that their mothers or sisters had experienced similar problems. 3. The subjects who were late or head left early rather than being absent from school every menstruation cycle were more stressful. The results are thought to show that the girl's perception of dysmenorrhea seems to be more sensitive than adult's one. 4, A significant negative correlation was found between the perception of menstrual flow and strees level. It means that an increase in the stress of dysmenorrhea was associated with decreased menstrual bleeding. The degree of hypochondrical concern assessed by the girls was significantly correlated to stress and coping level. When the girls perceived high stress as a result of dysmenorrhea, they worried about their physical health more. The above results lead us to the suggestion that the starting point of early education with a school program is appropriate for the 4th grade in primary school. Especially if the girls in middle school should be required to give the information about correct knowledge and sufficient self -care management of menstruation monthly, if this could be implemented the loss in school days among the students due to dysmenorrhea would be minimized with more ease.

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A Study on the Health Conditions of Male and Female Environmental Workers in Seoul (서울시 남$\cdot$여 환경미화원의 건강실태에 관한 고찰)

  • Kwon Young Eun;Suh Gil Hee;Kim Kyu-Sung;Choy Haeng-Gi;Jung Moon-Hee
    • Journal of Korean Public Health Nursing
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    • v.7 no.1
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    • pp.67-79
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    • 1993
  • This study was designed to identify the general health conditions and high risk factors of the male & female environmental workers. Thereby. the results of this study were to provide useful data as a contribution to knowledge for health protection and promotion. The data used for this study were environmental workers' physical examination cards; the male environmental workers were 52 persons. and the female environmental workers 52 persons. The data were analyzed by descriptive statistics, t-test, Pearson correlation, and distinction analysis, using the SPSS program. The results of this study can be summarized as follows; 1. Thers was a significant statistical difference between the two groups as to height. eyesight. serum GPT, hematocrit. The variables having little difference between two groups were weight. systolic blood pressure. total cholesterol. creatinine. 2. The rate of revealed in significant health examination was extra-health discrimination rate $28.8\%$, significant result of illness rate $12.5\%$. injury-inflicting rate $7\%$. second-time urine test $5.7\%$. antigen positive 3.8%. hearing impairment $2.8\%$, urine protein positive $1.9\%$. and urine sugar positive $1.9%$. 3. The workers diagnosed as extra-health discrimination were 30 persons or $28.8\%$. There was a difference between two groups on the prevalence. In the male environmental workers. ten times live problems and six times pulmonary tuberculosis and three times circulatory problems were revealed the higher than thoes of the female environmental workers. 4. In the male environmental workers, the relationship between age and systolic blood pressure revealed a significant correlation (r=0.22. p<0.05). In the female environmental workers. there was a negative correlation between age and weight (r= 0.25, p<0.05). the relationship between age and total cholesterol correlated positively (r=0.30, p<'0.05). 5. In the male environmental workers, there was a negative correlation between working career and creatinine(r=-0. 22, p<0.05) In the female environmental workers, there was a positive correlation between working career and total cholesterol (r= 0.58, p<0.01). 6. There were significant differences on working career and creatinine accdording to the male and female environmental workers who had any problems through x-ray inspection. 7. There were significant differences on height. eyesight. serum GPT according to the male and female environmental workers who were diagnosed as extra-health discrimination. 8. The female environmental workers who were diagnosed as 'care' were positively correlated with weight (r= 0.26. p<0.05)' and systolic blood pressure (r= 0.30. p<0. 05). on the other hand. the left and right eyesight correlated nagatively(r=-0.15. r=-0.33. p<0.01). 9. The most influential variables on the male and female environmental workers' health condition were working career, height. and weight. And these three variables could help determine the two groups at the level of 81. 8 percentage.

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A Scheme for Identifying Malicious Applications Based on API Characteristics (API 특성 정보기반 악성 애플리케이션 식별 기법)

  • Cho, Taejoo;Kim, Hyunki;Lee, Junghwan;Jung, Moongyu;Yi, Jeong Hyun
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.26 no.1
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    • pp.187-196
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    • 2016
  • Android applications are inherently vulnerable to a repackaging attack such that malicious codes are easily inserted into an application and then resigned by the attacker. These days, it occurs often that such private or individual information is leaked. In principle, all Android applications are composed of user defined methods and APIs. As well as accessing to resources on platform, APIs play a role as a practical functional feature, and user defined methods play a role as a feature by using APIs. In this paper we propose a scheme to analyze sensitive APIs mostly used in malicious applications in terms of how malicious applications operate and which API they use. Based on the characteristics of target APIs, we accumulate the knowledge on such APIs using a machine learning scheme based on Naive Bayes algorithm. Resulting from the learned results, we are able to provide fine-grained numeric score on the degree of vulnerabilities of mobile applications. In doing so, we expect the proposed scheme will help mobile application developers identify the security level of applications in advance.

Facial Expression Control of 3D Avatar by Hierarchical Visualization of Motion Data (모션 데이터의 계층적 가시화에 의한 3차원 아바타의 표정 제어)

  • Kim, Sung-Ho;Jung, Moon-Ryul
    • The KIPS Transactions:PartA
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    • v.11A no.4
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    • pp.277-284
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    • 2004
  • This paper presents a facial expression control method of 3D avatar that enables the user to select a sequence of facial frames from the facial expression space, whose level of details the user can select hierarchically. Our system creates the facial expression spare from about 2,400 captured facial frames. But because there are too many facial expressions to select from, the user faces difficulty in navigating the space. So, we visualize the space hierarchically. To partition the space into a hierarchy of subspaces, we use fuzzy clustering. In the beginning, the system creates about 11 clusters from the space of 2,400 facial expressions. The cluster centers are displayed on 2D screen and are used as candidate key frames for key frame animation. When the user zooms in (zoom is discrete), it means that the user wants to see mort details. So, the system creates more clusters for the new level of zoom-in. Every time the level of zoom-in increases, the system doubles the number of clusters. The user selects new key frames along the navigation path of the previous level. At the maximum zoom-in, the user completes facial expression control specification. At the maximum, the user can go back to previous level by zooming out, and update the navigation path. We let users use the system to control facial expression of 3D avatar, and evaluate the system based on the results.

Development of Non-sintered Construction Materials for Resource Recycling of the Flotation Tailings (부선(浮選) 광미(鑛尾)의 순환자원화(循環資源化)를 위한 비소성(非燒成) 토건재료(土建材料) 개발(開發))

  • Kim, Joo-Ik;Jung, Moon-Young;Park, Jay-Hyun;Lee, Jin-Soo
    • Resources Recycling
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    • v.20 no.1
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    • pp.37-45
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    • 2011
  • This study was conducted to recycle flotation tailings as non-sintered construction materials considering the economic and eco-friendly treatments. The particle size distribution( median $220\;{\mu}m$) of flotation tailings from Soon-shin mine was confirmed to be larger than that(median $140\;{\mu}m$) of tailings from Sam-kwang mine. Thus we investigated the properties of non-sintered eco-brick producted with the tailings from Sam-kwang mine and non-sintered water permeable block producted with the tailings from Soon-shin mine. Compressive strength of non-sintered water permeable block which was made with less than 25 wt% of tailings from Soon-shin mine was met with products class(over 14.70 MPa) of water permeable concrete(EL 245) from KEITL. Meanwhile, the coefficient of its permeability wasn't met with the products class( over $1.0{\times}10^{-2}\;cm/sec$). The properties of non-sintered eco-brick with less than 40 wt% of tailings from Sam-kwang mine were satisfied with third class in sintered clay brick products standard(KS L 4201). The non-sintered eco-brick as a result of leaching test on heavy metals by KSLT was verified to be environmentally stabile.