• Korean Journal of Psychosomatic Medicine
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• v.7 no.1
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• pp.87-102
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• 1999

Objectives : The purposes of this study were to estimate the prevalence rate of eating disorders in Korean males and to clarify their characteristics in sociodemograhic data, the eating traits, and general psychopathology through the comparison with those of female high scored group on the Korean version of Eating Attitudes Test-26(KEAT-26). Methods : Using a multi-stage questionnaire sampling method including area sampling, proportionated stratified sampling, and quota sampling, we surveyed a total of 4,400 Korean adults over 18 in a nationwide area(9 kus, 10 middle or small cities, and 17 kuns), obtaining usable responses on 3,896. Of the 3,062 subjects(1249 males and 1813 females) who were available for analysis, we ascertained 52 males and 208 females who had high score($\geq$ cutoff point 21) on the KEAT-26. Results : 1) The proportion of this high score group was 1.7% in male and 6.8% in female with a sex ratio(male versus female) of 1 : 4. 2) The mean age was higher in the male group than in the female group, although it was not statistically significant(p=0.0514). Mean Body Mass Index(BMI) of the male group was significantly higher than that of female group, and the number of male subjects with below 20 of BMI was also significantly lower than in the female group. 3) There were no significant difference in past history of physical illness between two groups. However, frequency of smoking and alcohol use, and mean amount of alcohol consumption per month were significantly higher in the male group than in the female group. There were no significant differences between the two groups on various socio-demographic correlates such as economic status, total duration of education, number of family, marital status, religious status, and area of residence, but the exception of being occupational status. 4) The 'Eating Habits Scale' score and score of 'preference for vegetables and fish, and dislike for sweet-tasting food' of the male group were significantly lower than those of the female group. Although there was no significant difference between the two groups in total scores of the KEAT-26, the mean score on 'pursuit of thinness' subscale was higher in the female group than in the male group, while scores of 'food preoccupation' and 'self-control' subscales were higher in the male group than in the female group. 5) Scores on 'psychoticism' was significantly higher in the male group than in the female group, although there were no significant differences between the two groups on 'locus of control for weight', 'depression' and 'hypochondriasis'. Conclusion : These results support a possibility of a high prevalence of eating disorders in Korean males. These results suggest that eating related characteristics of high scorer on the EAT are different by sex in spite of the same high score on the EAT, and also suggest that male patients with eating disorders have more serious personality pathology than female patients with eating disorders.

• Tuberculosis and Respiratory Diseases
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• v.44 no.3
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• pp.534-546
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• 1997

Background : The p53 and retinoblastoma(Rb) tumor suppressor genes are associated with the pathogenesis of several types of human cancer. Substantial proportion of the primary lung cancers or cell lines have been reported to have the p53 and/or the Rb gene mutations. But, so far there is no report on the analysis of the Rb gene polymorphism as one of the genetic susceptibility marker. This study was undertaken to establish the gene frequencies of the polymorphic genotypes of the p53 and Rb genes in Koreans to evaluate the possible involvement of these genotypes as a risk factor of lung cancer. Methods : In this study 145 controls without previous and present tumor history and 128 lung cancer patients were subjected to analysis. The two intragenic polymorphisms of the p53 gene(exon 4/ AccII, intron 6/MspI) and one intron 17/XbaI polymorphism of the Rb gene were analysed by the method of polymersae chain reaction- restriction fragment length polymorphisms(PCR-RFLPs). The genotype of the intron 3/16 bp repeat polymorphism of p53 was determined by PCR and direct gel electrophoresis. Results : There were no significant differences in the genotype distributions of the p53 gene between lung cancer patients and controls. But heterozygotes(Arg/Pro) of the exon 4/AccII polymorphisms were slightly over-represented than controls, especially in the Kreyberg type I cancer, which was known to be associated with smoking. The intron 3/16 bp duplication and the intron 6/MspI polymorphisms were in complete linkage disequilibrium. About 95% of the individuals were homozygotes of the common alleles both in the 16 duplication and MspI polymorphisms, and no differences were deteced in the genotype distributions between lung cancer patients and controls. Overall genotype distributions of the Rb gene polymorphisms between lung cancer patients and controls were not significantly different However, the genotype distributions in the Kreyberg type I cancer were significantly different from those of controls(p = 0.0297) or adenocarcinomas(p = 0.0008). It was noticeable that 73.4% of the patients with adenocarcinomas were heterozygotes(r1/r2) whereas 39.2% of the Kreyberg type I cancer were heterozygous at this polymorphisms. In the lung cancer patients, significant differences were also noted between the high dose smokers and low dose smokers including non-smokers(p = 0.0258). The relative risk to Kreyberg type I cancer was significantly reduced in the individuals with the genotype of r1/r2(odds ratio = 0.46, 95% C.I. = 0.25-0.86, p = 0.0124). The combined genotype distribution of the exon 4 AccII of the p53 and the intron 17 Rb gene polymorphisms in Kreyberg type I cancers were significantly different from dose of controls or adenocarcinomas. The highest odds ratio were observed in the individuals with the genotypes of Arg/Pro and r2/r2(odds ratio = 1.97,95% C.I. = 0.84-4.59) and lowest one was in the patients with Arg/Arg, r1/r2 genotype(odds ratio = 0.54, 95% C.I. = 0.25-1.14). Conclusion : The p53 and the Rb gene polymorphisms modulate the risk of smoking induced lung cancer development in Koeans. However, the exact mechanism of risk modulation by these polymorphism remains to be determined. For more discrete clarification of associations between specific genotypes and lung cancer risk, the evaluations of these polymorphisms in other ethnics and more number of patients will be needed.

• Proceedings of the Korean Aquaculture Society Conference
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• 2003.10a
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• pp.119-120
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• 2003

우리나라에 분포하는 모자반류는 모두 28종으로 알려져 있으며 (이와 강 2002) 이 가운데 식용으로 이용되는 것은 모자반 (S. fulvellum)이 대표적이다. 모자반의 양식은 주로 서남해 지역에서 이루어지고 있으며 이들의 종묘생산은 자연에서 생식기탁이 성숙되는 4-5월경에 이루어지는데, 유배의 대량 방출을 위한 성숙 모조의 다량 확보가 어렵고 일시에 유배의 대량 방출을 유도하기 위한 성숙 유도 기법의 연구는 전무한 실정이다. 따라서 이 연구에서는 모조의 실내 배양을 통하여 유배의 대량 방출을 위한 성숙 유도 기법과 배양 조건별 엽체의 성숙 및 난방출율을 구하여 모자반의 조기채묘에 유용한 자료로 사용하고자 하였다. 또한 채묘된 발아체의 초기생장에 필요한 최적 배양 환경을 구명하고자 하였다. 모자반 모조는 전남 진도군 조도 지역의 수심 3-5m에서 채집하였으며, 채집 즉시 실험실로 운반하여 유수식 사육 수조에 수용하였다. 성숙 유도는 20$\ell$ 플라스틱 bottle을 사용하였으며, 성숙률의 정량화를 위하여 암생식기탁을 절단하여 수차례 멸균해수에서 세척후 멸균된 5cm직경의 petri dish에 멸균해수20$m\ell$와 함께 수용하여 Multi-chamber incubator에서 배양하였다. 배양조건은 5개 온도조건 (5, 10, 15, 20, $25^{\circ}C$)과16:8h의 장일 광주기 조건으로하였으며 조도는 80 $\mu$molm$^{-2}$ s$^{-1}$로 하였다. 모든 실험구는 3반복 실험하였으며 2일 간격으로 생식기탁의 생장 및 성숙 그리고 난방출 여부를 현미경하에서 측정하였다. 난이 방출된 모조로부터 유배를 분리하여 3개 조도 구간 (30, 60, 100 $\mu$molm$^{-2}$ s$^{-1}$)과 5개 온도 구간 (5, 10, 15, 20, $25^{\circ}C$)의 조합인 15개 배양 조건하에서 엽체의 길이생장을 측정하였다. 생식기탁으로부터 난의 방출은 15$^{\circ}C$와 2$0^{\circ}C$ 조건에서 배양 2일후부터 방출되기 시작하였으며, 배양 9일후 2$0^{\circ}C$ 조건에서 가장 높은 96.7$\pm$5.8%의 난방출율을 보였다. 또한 15$^{\circ}C$ 조건에서는 배양 9일후 76.7%의 난방출율을 보였다. 1$0^{\circ}C$와 $25^{\circ}C$ 조건에서는 배양 11일까지 36.7%의 난방출율을 나타내어 온도 조건에 따라 난방출 비율에 차이를 보였다. 따라서 이러한 실내 배양 결과를 다량의 모조를 조기에 성숙시키기 위해 모조 수용 수조의 수온을 자연수온보다 2~5$^{\circ}C$ 높은 12~15$^{\circ}C$ 조건으로 유지하여 15일간의 수조 관리 후 모조의 대량 유배 방출을 유도할 수 있었다. 모조 성숙을 위한 사육 수조의 수온을 2$0^{\circ}C$ 이상으로 가온할 경우 엽체의 끝녹음을 유발하였으며 가온에 따르는 가온 비용이 수반되므로 엽체의 난방출율이 70% 이상에 도달하는 15$^{\circ}C$ 조건으로 유지하는 것이 경제적일 뿐만 아니라 엽체의 건전도 유지에도 바람직하였다. 유배의 초기생장은1$0^{\circ}C$와15$^{\circ}C$의 온도조건에서 길이생장이 빠르게 증가하여, 배양 35일 후 15$^{\circ}C$와 60 $\mu$molm$^{-2}$ s$^{-1}$의 조건에서 3.9$\pm$0.2mm로 가장 높은 값을 나타내었다. 엽체의 초기 길이생장은 15$^{\circ}C$, 60 $\mu$molm$^{-2}$ -s$^{-1}$의 조도 조건에서 가장 우세하였으며, 다음으로 30과 100 $\mu$molm$^{-2}$ s$^{-1}$의 조건 순으로 나타났다. 2$0^{\circ}C$와 $25^{\circ}C$의 온도 조건에서는 각각 1.8~2.1mm로 길이생장에 있어 유의한 차이가 없는 것으로 나타났다.

• The Journal of the Petrological Society of Korea
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• v.27 no.3
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• pp.139-151
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• 2018

The Songgang-ri area, Cheongsong-gun, which is located in the Sobaeksan province of Yeongnam Massif near the southwestern boundary of Yeongyang subbasin of Gyeongsang Basin, consists of age unknown metamorphic rocks (banded gneiss, granitic gneiss, limesilicates) and age unknown igneous rock (granite gneiss) which intrudes them. This paper researched the geological structures of the Songgang-ri area from the geometric and kinematic features and the developing sequence of multi-deformed rock structures in the geological outcrops exposed about 170 m along the riverside of Yongjeoncheon in the eastern part of Songgang village, Songgang-ri. In the Songgang-ri geological outcrops are recognized three times (Fn, Fn+1, Fn+2) of folding, three times (Dk-I, Dk-II, Dk-III) intrusion of acidic dykes, one time of faulting, which are different in deformation and intrusion timing each other. These geological structures are at least formed by five times (Dn, Dn+1, Dn+2, Dn+3, Dn+4) of deformation. The Dn deformation is recognized by Fn fold which axial surface is parallel to the regional foliation. The Dn+1 intruded the (E)NE trending Dk-I dyke in the earlier phase and formed the NW trending Fn+1 fold in the later phase under compression of (E)NE-(W)SW direction. There are tight, isoclinal, intrafolial folds, boudinage, ${\sigma}$- or ${\delta}$-type boudins, asymmetric fold, C' shear band as the major deformed rock structures. The Dn+2 intruded the (N)NW trending Dk-II dyke in the earlier phase and formed NE trending Fn+2 fold in the later phase under compression of (N)NW-(S)SE direction. There are open fold and folded boudinage as those. The Dn+2 intruded the Dk-III dyke which cuts the Dk-I and Dk-II dykes and the axial surface of Fn+2 fold. The Dn+3 formed the left-handed reverse oblique-slip fault of NNE trend in which hanging wall moves into the SSE direction. Considering in that such five times of deformation recognized in the Songgang-ri geological outcrops are closely connected to the distribution and geological structure of the constituents in the more regional area as well as Songgang-ri area, the research result is expected to play a great data in clarifying and understanding the geological structure and its development process of the surrounding and boundary constituents of the Yeongnam Massif and Gyeongsang Basin.

• Journal of the korean academy of Pediatric Dentistry
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• v.33 no.4
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• pp.661-672
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• 2006

This study was performed to compare the shear bond strength of AQ Bond $Plus^{TM}$ with AQ $Bond^{TM}$ and Single $Bond^{TM}$. Also by observing the fractured interface under scanning electro-microscope, the fracture pattern and the quality of hybrid layer were analyzed. The possibility of clinical application of all-in-one system which has an advantage to reduce chair time for children with difficult behavior pattern was evaluated, The results obtained are as follows ; 1. There was no significant difference between AQ $Bond^{TM}$ and AQ Bond $Plus^{TM}$ in shear bond strength and Single Bond showed the highest bond strength with statistical significant difference (p<0.05). 2. Adhesive fracture pattern was mainly observed in both enamel/dentin in AQ $Bond^{TM}$ and AQ Bond $Plus^{TM}$ group while Single Bond group showed equal numbers for cohesive and adhesive pattern. 3. Under scanning electro-microscope, resin tags observed in AQ $Bond^{TM}$ and AQ Bond $Plus^{TM}$ were very weak and tangled while strong and thick tags were shown with many lateral branches in Single Bond. Careful case selection and accurate clinical application is recommended when using AQ $Bond^{TM}$ and AQ Bond $Plus^{TM}$considering the result showing its weaker strength than Single $Bond^{TM}$.

• Journal of Korean Ophthalmic Optics Society
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• v.21 no.3
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• pp.235-242
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• 2016

Purpose: This study was to investigate whether the application of different diagnostic criteria affected the frequency of convergence insufficiency (CI). Methods: Eighty one subjects with mean age of 22.54 years (20 to 27 years) were evaluated. Binocularity tests after refraction were performed as the following tests: near point of convergence (NPC) with an accommodative target, phoria using von Graefe method, positive fusional vergence (PFV) with a phoropter. Subjects with CI were diagnosed when exophoria (exo) was greater at near than at distance ($exo{\geq}4{\Delta}$, or >$6{\Delta}$), fusional vergence was $PFV{\leq}11{\Delta}$ for blur, $PFV{\leq}15{\Delta}$ for break, Sheard's or Percival's criterion, and NPC was $NPC{\geq}6cm$, ${\geq}7.5cm$ or >10 cm. Results: Frequency of CI with one diagnostic criterion was ranged from 6.2% to 77.8%, and was overestimated or underestimated according to criteria. It was reduced to the range of 6.2% to 43.2% with diagnostic criteria more than two, especially to the range of 24.7% to 28.4% with lower variability in diagnostic criteria including phoria and Sheard's criterion. There were high relationship between total score of signs and phoria score (r = 0.772, p<0.001), and measured phoria and Sheard's criterion (r = -0.654, p<0.001), but NPC had a high variability and a weak or no significant relationship with other diagnostic criteria. Results suggested $exo{\geq}4{\Delta}$, Sheard's criterion and $NPC{\geq}7.5cm$ for diagnostic criteria of signs and sequence for CI. Conclusions: Frequency of CI is likely to be over- and underestimated with diagnostic criteria. Cutoff values and procedures for phoria, Sheard's criterion and NPC as clinical signs should be suggested definitely in diagnosis associated with CI.

• Journal of Preventive Medicine and Public Health
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• v.36 no.2
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• pp.93-100
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• 2003

Objectives : Because shipyard workers are involved with various manufacturing process, they are exposed to many kinds of hazardous materials. Welders especially, are exposed to bisphenol-A (BPA) during the welding and flame cutting of coated steel, This study was conducted to assess the exposure status of the endocrine disrupter based on the job-exposure matrix. The effects of the genetic polymorphism of xenobiotic enzyme metabolisms involved in the metabolism of BPA on the levels of urinary metabolite were investigated. Methods : The study population was recruited from a shipyard company in the f province. A total of 84 shipbuilding workers 47 and 37 in the exposed and control groups, respectively, were recruited for this study. The questionnaire variables included, age, sex, use of personal protective equipment, smoking, drinking and work duration. The urinary metabolite was collected in the afternoon and correction made for the urinary creatinine concentration. The of the CYP1A1, CYP2E1 and UGT1A6 genotypes were investigated using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) methods with the DNA extracted from venous blood. Results : The urinary BPA level in the welders group was significantly higher than in the control group (p<0.05). The urinary BPA concentration with the wild type UGT1A6 was higher than the other UGT1A6 genotypes, but with no statistical significant. From themultiple regression analysis of the urinary BPA, the regression coefficient for job grade was statistically significant (p<0.05). Conclusions : The grade of exposure to BPA affected the urinary BPA concentration was statistically significant. However, the genetic polymorphisms of xenobiotics enzyme metabolism were not statistically significant. Further investigation of the genetic polymorphisms with a larger sample size is needed.

• Economic and Environmental Geology
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• v.46 no.6
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• pp.485-494
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• 2013

$CO_2$ Monitoring, Mitigation and Verification (MMV) is the essential part in the Carbon Capture and Storage (CCS) project in order to assure the storage permanence economically and environmentally. In large-scale CCS projects in the world, the seismic time-lapse survey is a key technology for monitoring the behavior of injected $CO_2$. In this study, we developed a basic process procedure for 3-D seismic baseline data from the Aquistore project, Estevan, Canada. Major target formations of Aquistore CCS project are the Winnipeg and the Deadwood sandstone formations located between 1,800 and 1,900 ms in traveltime. The analysis of trace energy and similarity attributes of seismic data followed by spectral decomposition are carried out for the characterization of $CO_2$ injection zone. High trace energies are concentrated in the northern part of the survey area at 1,800 ms and in the southern part at 1,850 ms in traveltime. The sandstone dominant regions are well recognized with high reflectivity by the trace energy analysis. Similarity attributes show two structural discontinuities trending the NW-SE direction at the target depth. Spectral decomposition of 5, 20 and 40 Hz frequency contents discriminated the successive E-W depositional events at the center of the research area. Additional noise rejection and stratigraphic interpretation on the baseline data followed by applying appropriate imaging technique will be helpful to investigate the differences between baseline data and multi-vintage monitor data.

• The Journal of Korean Academy of Prosthodontics
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• v.47 no.4
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• pp.424-434
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• 2009

Statement of problem: Problems such as loosening and fractures of retained screws and fracture of implant fixture have been frequently reported in implant prosthesis. Purpose: Implant has weak mechanical properties against lateral loading compared to vertical occlusal loading, and therefore, stress analysis of implant fixture depending on its material and geometric features is needed. Material and methods: Total 28 of external hexed implants were divided into 7 of 4 groups; Group A (3i, FULL $OSSEOTITE^{(R)}$Implant), Group B (Nobelbiocare, $Br{\aa}nemark$ $System^{(R)}$Mk III Groovy RP), Group C (Neobiotec, $SinusQuick^{TM}$ EB), Group D (Osstem, US-II). The type III gold alloy prostheses were fabricated using adequate UCLA gold abutments. Fixture, abutment screw, and abutment were connected and cross-sectioned vertically. Hardness test was conducted using MXT-$\alpha$. For fatigue fracture test, with MTS 810, the specimens were loaded to the extent of 60-600 N until fracture occurred. The fracture pattern of abutment screw and fixture was observed under scanning electron microscope. A comparative study of stress distribution and fracture area of abutment screw and fixture was carried out through finite element analysis Results: 1. In Vicker's hardness test of abutment screw, the highest value was measured in group A and lowest value was measured in group D. 2. In all implant groups, implant fixture fractures occurred mainly at the 3-4th fixture thread valley where tensile stress was concentrated. When the fatigue life was compared, significant difference was found between the group A, B, C and D (P<.05). 3. The fracture patterns of group B and group D showed complex failure type, a fracture behavior including transverse and longitudinal failure patterns in both fixture and abutment screw. In Group A and C, however, the transverse failure of fixture was only observed. 4. The finite element analysis infers that a fatigue crack started at the fixture surface. Conclusion: The maximum tensile stress was found in the implant fixture at the level of cortical bone. The fatigue fracture occurred when the dead space of implant fixture coincides with jig surface where the maximum tensile stress was generated. To increase implant durability, prevention of surrounding bone resorption is important. However, if the bone resorption progresses to the level of dead space, the frequency of implant fracture would increase. Thus, proper management is needed.

• The korean journal of orthodontics
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• v.32 no.5 s.94
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• pp.343-353
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• 2002

This study was designed to investigate the stress distribution of alveolar bone in case of on masse retraction with lingual K-loop archwire using the 3-dimensional photoelastic stress analysis followed by stress freezing process. Lingual K-loop archwire which had loop in 15mm height was used and activated by retraction force of 350gm per each side. The results were as follows 1. Central incisor : As the closer side to crown, the larger tensile stress was distributed at both mesial and labial surfaces and the larger compressive stress was distributed at distal surface. As the closer side to root apex, the larger compressive stress was distributed at lingual surface. The compressive stress was distributed at root apex. 2. Lateral incisor : The tensile stress was distributed at the coronal side of mesial surface. The compressive stress was distributed at distal surface. As the closer side to crown, the larger tensile stress was distributed at labial surface. The tensile stress was distributed at coronal side and the compressive stress was distributed at apical side of lingual surface. The compressive stress was distributed at root apex. 3. Canine The tensile stress was distributed at coronal side and the compressive stress was distributed at apical side of mesial surface. The tensile stress was distributed at distal surface. As the closer side to crown, the larger tensile stress was distributed at both mesial and distal surfaces. The compressive stress was distributed at root apex. 4. Second premolar : The tensile stress was distributed at mesial surface. The compressive stress was distributed at coronal side and the tensile stress was distributed at apical side of distal surface. The compressive stress was distributed at coronal side of buccal surface. As the closer side to crown, the larger tensile stress was distributed at lingual surface. The compressive stress was distributed at root apex. 5. First molar . As the closer side to crown, the larger tensile stress was distributed at both mesial and distal surfaces. No stress was distributed at buccal surface and palatal root apex. As the closer side to crown, the larger tensile stress was distributed at both lingual surfaces. The compressive stress was distributed a4 buccal root apexes. 6. Second molar The compressive stress was distributed at all root apexes. As the closer side to crown, the larger compressive stress was distributed at both mesial and lingual surfaces, and the larger tensile stress at both distal and buccal surfaces. Transverse bowing effect was observed in on-masse retraction with lingual K-loop archwire, however vertical towing effect was not. Rather, reverse vortical bowing effect was developed.