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A case of atypical hemolytic uremic syndrome as an early manifestation of acute lymphoblastic leukemia (비전형적 용혈성 요독 증후군으로 조기 발현한 급성 림프모구성 백혈병 1예)

  • Han, Dong Kyun;Baek, Hee Jo;Cho, Young Kuk;Kim, Chan Jong;Shin, Myung Geun;Kook, Hoon;Hwang, Tai Ju
    • Clinical and Experimental Pediatrics
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    • v.53 no.2
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    • pp.253-257
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    • 2010
  • Hemolytic uremic syndrome (HUS) is the most common cause of acute renal failure in children younger than 4 years and is characterized by microangiopathic hemolytic anemia, acute renal failure, and thrombocytopenia. HUS associated with diarrheal prodrome is usually caused by Shiga toxin-producing Escherichia coli O157:H7 or by Shigella dysenteriae, which generally has a better outcome. However, atypical cases show a tendency to relapse with a poorer prognosis. HUS has been reported to be associated with acute lymphoblastic leukemia (ALL) in children. The characteristics and the mechanisms underlying this condition are largely unknown. In this study, we describe the case of an 11-year-old boy in whom the diagnosis of ALL was preceded by the diagnosis of atypical HUS. Thus, patients with atypical HUS should be diagnosed for the possibility of developing ALL.

Spontaneous Pneumothorax associated with Thoracic Endometriosis - Report of a case- (흉부 자궁내막증에 의한 자연 기흉 - 1예 보고 -)

  • Cho Jung Soo;Kim Young Sam;Kim Joung Taek;Baek Wan Ki;Lee Kyung Hi;Kim Lucia;Kim Kwang Ho
    • Journal of Chest Surgery
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    • v.38 no.7 s.252
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    • pp.518-521
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    • 2005
  • Pneumothorax associated with thoracic endometriosis is a rare clinical entity and it is called catamenial pneumothorax if the recurrence of pneumothorax is related to the period of menstruation. Several hypotheses about its pathogenesis are suggested including spontaneous rupture of the bulla, endometrial implants of the visceral pleura, and passage of air from the genital tract through endometrial fenestration of the diaphragm. Pneumothorax is associated with chest pain and dyspnea within 72 hours of the onset of menses in young women and developed usually at right side. We report a case of 32-year-old woman who had bilateral pneumothorax and thoracic endometriosis confirmed histopathologically in the visceral pleura by thoracotomy.

A Case of Nocardiosis (Nocardiosis 1예)

  • Kim, Jeong-Hee;Yoon, Ki-Heon;Yoo, Jee-Hong;Kang, Hong-Mo;Suh, Jin-Tae
    • Tuberculosis and Respiratory Diseases
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    • v.39 no.4
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    • pp.355-360
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    • 1992
  • Nocardiosis is an acute, subacute or chronic infection, which usually introduced through the respiratory tract resulting pneumonia, and may develop a disseminated infection, especially subcutaneous abscess and/or CNS infection. It is usually affects the immunocompromized host and may be fatal unless early diagnosis and adequate treatment are performed. There have been only several case reports of nocardial infection in Korea. Nocardiosis is so unfamiliar to many physicians that may be misdiagnosed as pneumonia, tuberculosis, or neoplasm. We have experienced a case of nocardiosis from a patient who had been treated as pneumonia and tuberculosis at first. The 57-year-old male patient had fever, chill, dyspnea and blood tinged purulent sputum for 20 days. Under the impression of bacterial pneumonia, broad spectrum antibiotics were administered for more than 3 weeks without clinical improvement. Although antituberculous drugs began to be administered after acid fast bacilli were found in bronchial aspirate by bronchoscopy, the nocardial infection was suspected due to no clinical response toward antituberculous therapy and the occurrence of multiple subcutaneous abscesses on scalp. The diagnosis was made by modified Ziehl-Neelson stain and culture of the sputum and pus. Nocardia asteroides was identified. After 25 days of trimethoprim-sulfamethoxazole treatment, the patient was much improved and discharged.

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A Case of Renal Cell Carcinoma Presented with Chest Wall Metastasis (전흉벽와 피하조직내 종괴로 발현한 원발성 신장암 1예)

  • Song, Chan-Ho;Choi, Hyung-Seok;Sheen, Dong-Hyuk;Yang, Sang-Seok;Lee, Jee-Youn;Han, Yoon-Ju;Yun, Ku-Sub;Kim, Ki-Chool;Choi, Shin-Eun
    • Tuberculosis and Respiratory Diseases
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    • v.48 no.1
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    • pp.84-90
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    • 2000
  • The appearance of a tumor in the chest wall is rare compared to that in any other part of the body. It can be classified into benign and malignant types and can be located in the rib, clavicle, sternum, cartilage and soft tissues. Tumors that are metastatic are commonly located in the lung, breast, bone and pleura. But, the soft tissue mass of anterior chest wall is rarely metastasized from a distant organ that is not confined to the thoracic cavity. This and thus has rarely been described. A 68-year-old man was admitted to our hospital with a chief complaint of resting dyspnea. A huge non-tender mass of about $10{\times}15$ cm in size was visible on his left lower anterior chest wall. We pathologically confirmed that the mass was a metastatic renal cell carcinoma of clear cell type by incision biopsy. Through an incision biopsy, the mass was pathologically confirmed as a metastatic renal cell carcinoma of the clear cell type.

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The effects of adjective meaning on response to color: A test using Stroop task (형용사의 의미가 색 구별에 미치는 영향: 스트룹 과제를 통한 검증)

  • Hong, Seongkyun;Kim, Kyungho;Li, Hyung-Chul O.;Kim, ShinWoo
    • Korean Journal of Cognitive Science
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    • v.28 no.1
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    • pp.27-42
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    • 2017
  • Stroop effect(Stroop, 1935) is a reliable paradigm which has been used in various psychological research. Although classic Stroop experiment used color and color name for experimental stimuli, subsequent research reported that a color(e.g. green) and an object(e.g. grass) which displays a typical color show similar effects depending on color-object congruency(Klein, 1964). Because past research that used Stroop effect to investigate semantic representation tested association between concrete object and color, they predominantly used concrete nouns and their corresponding color names as stimuli(e.g. Dalrymple-Alford, 1968, 1972; Klein, 1964). Recently, Sherman and Clore(2009) reported that response time to white or black words is affected by moral value of words (e.g., honesty, crime) even when the words do not have specific referents. Based on this result, we tested association between thermesthesia-related adjectives(e.g., 따스한, 냉정한) and color(warm color, cold color) using Stroop task. The results showed that subjects were faster in their response to color when adjective-color was congruent than when incongruent, and there was an interaction between color and meaning of adjectives. The Stroop effect in this research is unique because, contrary to previous research that used concrete nouns, the effect was obtained even with abstract adjectives which do not have specific referents. In addition, unlike Sherman and Clore(2009) that used achromatic color, our results show that Stroop effect obtains between abstract adjectives and chromatic color.

A Study on the Association of Thin Glomerular Basement Membrane Abnormality with Minimal Change Nephrotic Syndrome (사구체 기저막 비박화 소견을 보인 미세변화 신증후군에 관한 고찰)

  • Kim, Chang-Woo;Cho, Min-Hyun;Ko, Cheol-Woo;Koo, Ja-Hoon;Kwak, Jung-Sik
    • Childhood Kidney Diseases
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    • v.6 no.1
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    • pp.48-55
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    • 2002
  • Purpose: Thin glomerular basement membrane nephropathy (TGBMN) is recognized as the leading cause of microscopic hematuria in both children and adults. However thinning of glomerular basement membrane (TCBM) has been found in healthy adult and also is known to be associated with various renal diseases such as Alport syndronh, IgA nephropathy and mesangial proliferative glomerulonephritis. The association of TGBM with minimal change nephrotic syndrome (MCNS) has been very rare so that the present study was undertaken to determine the relationship between TGBM and MCNS. Methods: The study population consisted of 49 children with biopsy- proven MCNS who have been admitted to the pediatric department of Kyungpook University Hospital during the past 5 years from 1997 to 2001. Group I consisted of 8 children associated with TGBM and Group II 41 children without TCBM. Various parameters such as age of illness, duration from discovery of illness to the time of biopsy, family history of hematuria and other laboratory tests were compared between these two groups and the following results were obtained. Results: Age distribution showed slightly older age in Group I ($7.1{\pm}3.5$ years) compared to Group II ($4.8{\pm}2.9$ years). However this was not statistically different (P=0.056). Family history of hematuria was noted in 2 cases in Group II. Though statistically not significant, hematuria was seen in 2 out of 8 cases ($25\%$) in MCNS children with TGBM, compared to 7 out of 41 cases ($17\%$) with MCNS children without TGBM. Other parameters such as BUN, creatinine, 24 hours urine protein excretion, serum protein, albumin, cholesterol, and T4/T8 ratio, showed no difference. Also renal biopsy finding showed no significant difference and the thickness of glomerular basement membrane in Croup I was $188{\pm}30nm$. Conclusion: TGBM was found in 8 out of 49 children with MCNS ($16.3\%$). And this high frequency of occurrence indicates that these association is not an incidental findings. Typical clinical findings of TCBMN was not noted in all of the 8 children with MCNS associated with TGBM, suggesting that thinning of glomerular basement membrane (TCBN) is secondary to rather than the cause of MCNS. (J Korean Soc Pediatr Nephrol 2002;6: 48-55)

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The remediation strategy of e-sports (e-sports 의 재매개 전략)

  • Lee, Jong-Young
    • 한국HCI학회:학술대회논문집
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    • 2007.02b
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    • pp.713-719
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    • 2007
  • 한 미디어를 다른 미디어에서 표상하는 것을 재매개 remediation (이재현, 2006)라고 한다. 보통 재매개는 원 소스 멀티 유즈 혹은 재목적화 repurposing로 알려져 있다. 한 미디어가 다른 미디어를 통해 표상된다는 사실은 한가지 컨텐츠를 다양한 창구 혹은 채널을 통해 내보냄으로써 해당 컨텐츠의 가치를 극대화한다는 경영학적 의미뿐만 아니라, 미학적 사회학적 의미를 가진다. 특정한 미디어를 통해 보여지는 컨텐츠가 이질적인 다른 미디어를 통해 표상되면, 컨텐츠 뿐만 아니라 표상되는 미디어도 쉽게 인식하게 되면서 미학적 의미를 갖는다. 가령 액자 속에 들어있는 풍경화를 보는 순간, 액자라는 창을 넘어서 그림이 표상하는 풍경을 보려고 하지만, 액자 속의 퐁경화를 텔레비전을 통해 보게 되면, 시청자는 그림을 둘러싼 액자 혹은 그 그림이 위치한 미술관을 인식하기 마련이다. 또한 새롭게 등장하는 미디어와 그 종사자는 기존 미디어 혹은 종사자들의 사회적 지위를 표상하면서 기존 미디어의 지위를 이어받으려고 하면서 사회적 의미를 갖는다. 컴퓨터 게임이라는 미디어가 텔레비전을 통해 방송되는 e-sports는 디지털 컨텐츠의 전형적 재매개의 예가 될 수 있다. e-sports중계는 컴퓨터 게임 화면만을 보여주지 않는다. 게이머의 표정, 게임의 제반 정보를 나타내는 게임 화면의 세부 창들, 관중들의 반응, 해설자의 해설, 리플레이 화면 등을 동시 혹은 선형적으로 보여줌으로써, 시청자로 하여금 끊임없이 컴퓨터 게임이라는 미디어를 인식하게 한다. 또한 e-sports는 이름에서도 드러나듯이, sports의 사회적 지위를 표상한다. e-sports 플레이어들이 선수로 불리고, 이들이 프로 게임단을 조직해 활동한다. e-sports(스타크래프트의 경우)는 상설 경기장에서, 종종 체육관에서 대규모 관중들 앞에서 보여짐으로써 기존 sports 경기를 표상한다. 재매개는 새로운 미디어가 등장하면서 자연스럽게 취하는 전략이다. 새로운 미디어가 쏟아지는 디지털 미디어 시대, e-sports의 재매개 전략을 살펴봄으로써 새로운 미디어가 미학적, 사회적으로 자리잡을 수 있는 함의를 얻을 수 있다.

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Cinematic Imagination and Representation of State/Nation -Focusing on and (국가/민족에 대한 영화적 상상력과 재현 - <실미도>와 <한반도>를 중심으로)

  • Hwang, Hye-Jin
    • The Journal of the Korea Contents Association
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    • v.6 no.11
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    • pp.56-64
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    • 2006
  • It seems that there has been a tendency of faction film which reveals imagination of state/nation. As typical examples, & would show the relationship between some factional imagination and the project of blockbuster. In this regard, I've researched the tradition of cinematic representation of state/nation and some historical aspects which reveal the being of official films ruled by oppressive political intention. As a kind of discourse dealing with state/nation, & have specific strategy of representation. The analysis about that process might enable us to understand what is nationalism and what is the nature of ideological discourse consumed by faction-related products.

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Awareness of the Causes of Drug-Induced Liver Injury: A Case of Hepatotoxicity Resulting from Antipsychotics (사례로 본 한방임상에서 양약으로 인한 약인성간손상에 대한 인식 필요성)

  • Chang-gue Son
    • The Journal of Internal Korean Medicine
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    • v.44 no.4
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    • pp.751-756
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    • 2023
  • Objective: This study attempts to increase awareness of hepatotoxicity caused by antipsychotic drugs and to provide updated information on drug-induced liver injury (DILI) to physicians in Korean medicine (KM) clinics. Methods: This study presents a detailed case of a female patient diagnosed with DILI attributed to antipsychotic drugs, highlighting the improvement observed through laboratory findings. Results: A 56-year-old female patient with underlying disorders, including mixed connective tissue disease and depression, was under medical care. One day, she reported experiencing intense fatigue and distressing sensations, prompting the author to order blood tests. The levels of AST and ALT were significantly elevated by more than 2.5-fold, indicating hepatocellular DILI. The RUCAM score for antipsychotic drugs was 9, as no other medications, including herbal medicine, were being taken. Upon discontinuation of the antipsychotic drugs, the patient's laboratory findings returned to normal levels within 2 weeks, accompanied by a recovery of subjective symptoms. Conclusion: This study presents a noteworthy case of hepatotoxicity caused by antipsychotic drugs, serving as an illustrative example that highlights the crucial need for awareness among doctors of KM in clinical settings.

Clinical features of transient small bowel intussusception in children (소아에서의 일과성 소장형 장중첩증의 임상적 고찰)

  • Heo, Ji Seung;Seo, Eun Min;Shim, Eun Jung;Cho, Do Jun;Kim, Dug Ha;Min, Ki Sik;Yoo, Ki Yang;Lee, Kwan Seop
    • Clinical and Experimental Pediatrics
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    • v.51 no.5
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    • pp.500-505
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    • 2008
  • Purpose : We analyzed the clinical features, management and outcome of small bowel intussusception in children compared with ileocolic intussusception. Methods : We retrospectively reviewed the records of 210 children with documented intussusception, in whom intussusception was initially diagnosed by ultrasonography during the four-year period of 2002 to 2005. Results : A total of 191 children were diagnosed with ileocolic intussusception and 19 were diagnosed with small bowel intussusception. Children with small bowel intussusception were older than children with ileocolic intussusception (P<0.05). In comparison to patients with ileocolic intussusception the characteristic presenting symptoms- such as currant jelly stool and palpable mass- were rarely observed in patients with small bowel intussusception. In ileocolic intussusception, air reduction (92.2%), or surgical reduction (7.3%) was performed; however, in small bowel intussusception, spontaneous reduction (78.9%) was observed and no surgical reduction was required in our study. Conclusion : Conservative management with close observation and follow-up sonographic evaluation rather than an immediate operation is recommended for children with small bowel intussusception.