• Pediatric Infection and Vaccine
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• v.19 no.1
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• pp.1-11
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• 2012

Purpose : Although influenza is regarded as one of the major causes of morbidity and mortality in children with cancer, the actual vaccine coverage remains poor. We conducted evaluation of immunogenicity and safety of influenza vaccine in children with cancer. Methods : In this study, 25 children with cancer who received influenza vaccine (SK influenza IX vaccine$^{(R)}$) at the Korea Cancer Center Hospital between October and December 2009 were analyzed. Blood samples of patients were collected twice (at the beginning of this study and at 30th day after vaccination) and their antibody titers were measured using the hemagglutination-inhibition (HI) assay. Immunogenicity of the influenza vaccine was assessed by seroprotection rate on days 0 and 30, seroconversion rate on day 30, and mean fold increase (MFI) of geometric mean titer (GMT) of HI between days 0 and 30. Results : Any of the subjects in our study did not experienced serious adverse events after influenza vaccination. Seroprotection rates were 68% for H1N1, 40% for H3N2, and 36% for B. Seroconversion rates were 12% for H1N1, 16% for H3N2, and 20% for B. MFIs were 0.9 for H1N1, 1.2 for H3N2, and 1.8 for B. Conclusion : In the study, we found a limited protective immune response to influenza vaccine, among subjects with cancer. However, some subjects showed seroconversion, and there were no severe adverse events among all subjects, supporting the recommendation of annual influenza vaccination in children with cancer.

• Journal of Korean Society of Environmental Engineers
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• v.32 no.5
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• pp.469-476
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• 2010

The purpose of the study is to find ways to decrease turbidity and residual aluminum by improving the efficiency of coagulation process through controlling the pH of the source water with $CO_2$ when the pH increases by algal bloom or by the characteristics of the source water. Water quality parameters were monitored before and after $CO_2$ addition in February, March, April, and December, when the pH of the source water is over 8.0 and constant regardless of day and night. Water quality parameters closely related with evaluation of treated drinking water quality were monitored in detail, e.g. aluminum, turbidity, particle counts, TOC, THMs, 2-MIB, and geosmin. According to the results, inorganic water quality parameters such as turbidity, particle counts, and aluminum were decreased due to improved efficiency of the coagulation process. It was concluded that the pH of the water in the arrival basin must be controlled below 7.4 by adding $CO_2$ when the pH of the source water increasing. By controlling pH with $CO_2$, the water quality could be maintained within the drinking water quality goal of Seoul City (<30 particle/mL of particle count, <0.05 NTU of turbidity and <0.02 mg/L of aluminum). The change of the pH could not affect the concentrations of DBP's (e.g., THMs, CH, and HAAs) and taste/odor causing compounds (e.g., 2-MIB and geosmin). 2-MIB and geosmin were affected more by their initial concentrations in the source water.

• Journal of Korean Society of Environmental Engineers
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• v.28 no.6
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• pp.677-686
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• 2006

This study was the effectiveness of two downflow BAF(Biological Aerated Filter) systems at conventional water treatment system. A BAF reactor placed in front of coagulation and sedimentation tanks(Mode A) and after coagulation and sedimentation tanks(Mode B) that were compared in terms of removal of suspended particles, organic matters, and ammonia nitrogen. The suspended particles removal efficiency was over 80% for both Mode A and B, although Mode A gave slightly better results. $BOD_5$ removal and nitrification efficiencies were more than 90% for both reactor. The organic matter and ammonia removals were also superior in the Mode A. The biofilm thickness and biomass increased as increment of EBCT and the upper part of reactor more about 30% than lower part. The specific oxygen uptake rate(SOUR) was higher the upper part of reactor and Mode A than the lower part of reactor and Mode B. A cost analysis showed that the Mode A system was more cost effectiveness. It could save the coagulant dose by about 67% and the chlorine demand by about 95%. The ideal place to put the BAF reactor was in front of the coagulation/sedimentation process.

• The Journal of the Korea Contents Association
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• v.15 no.5
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• pp.582-591
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• 2015

Late-Koryeo people networks were constructed from four different history books that were written by various historic aspects in the period from king Kongmin to the final king of the Koryeo, Kongyang. All networks constructed in this study show scale free network properties as if most social networks do. Tajo-sillok preface is one of subjectively written history book that described personal history of the Lee Seong-gye and his ancestors. It is confirmed that the book is one of the most biased-written history books through network study. Jeong Do-jeon known as a Chosun dynasty projector is not greatly contributed for founding of a Chosun dynasty in network study and various historical documents as well. In this network study, we provide objective historical information in the historical situations of the late-Koryeo and during establishment procedure of Chosun dynasty. Hub nodes in network is denoted highly linked nodes, called degree. Stress centrality is a unit to measure positional importancy in the network. If we employ two factors, degree and stress centrality to determine hub node, it represents high connectivity and importancy as well. As comparing values of the degree and stress centrality, we elucidate more objective historical facts from late-Koryeo situations in this study. If we further develop and employ a new algorithm that is considered both degree and stress centrality, it is a very useful tool for determining hub node.

• Food Science and Preservation
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• v.18 no.4
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• pp.527-534
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• 2011

The purpose of this studies was analyzed moisture content, rheology and sensual test of jujube jungkwa by addition of water, sugar, fructose at processing of jujube jungkwa for development the optimization for processing of jujube jungkwa. The changes of moisture contents at process condition of jujube jungkwa were increased by increasing of sugar and water quantity. And moisture contents of jujube jungkwa were increased by high fructose quantity and low sugar quantity, but were decreased by high sugar and fructose quantity. The 'b' values of jujube jungkwa at low sugar quantity were decreased by the increasing of water quantity, but increased at high sugar quantity. The cohesiveness of jujube jungkwa at 0.03 kg of fructose were high by the increasing of sugar quantity, but those at 0.065 kg of fructose were high by the decreasing of sugar quantity. And those at 0.050 kg of fructose were similar without the quantity of sugar. The sweet taste of jujube jungkwa were increased by the increasing of water and fructose quantity. The characteristics of jungkwa at conditions of processing for the best quality of jujube jungkwa were 18-20% of moisture content, 2.0-3.0 of 'b' values, 3.0-3.2 of color scores, and 3.3-3.4 of sweet taste scores. The conditions of processing for the best quality of jujube jungkwa were determined to 0.95-1.04 L of water, 0.052-0.060 kg of fructose at 0.95 kg of sugar.

• Journal of Life Science
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• v.32 no.4
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• pp.303-309
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• 2022

Dystaenia takesimana is an endemic plant found only in Korea, especially on Ulleung Island. The leaves and roots of D. takesimana have been used as food, forage, and oriental medicine. Anti-bacterial, anti-inflammation, antioxidant, and α-glucosidase inhibition biological activities have been reported in the plant's root extract. However, studies concerning the anti-thrombosis activities of D. takesimana are still in the rudimentary stage. In this study, the extracts of the leaf (DT-L), stem (DT-S), and root (DT-R) of D. takesimana were prepared using 70% ethanol, and their anti-thrombosis activities were evaluated. DT-L extracts (0.25 mg/ml) showed strong inhibitions against platelet aggregation, comparable to aspirin, with strong radical scavenging activities. Furthermore, the DT-L extract did not show any RBC hemolysis up to 1 m/ml. The ant-coagulation and antioxidant activities of the DT-S extract were ignorable. While the DT-R extract showed inhibitions against thrombin and blood coagulation factors, it also showed strong platelet aggregation. This is a first report of the anti-thrombosis activities of D. takesimana, and our results suggest that DT-L could be developed as a valuable bioresource for high value-added products.

• Journal of Life Science
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• v.26 no.1
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• pp.83-90
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• 2016

This study was investigated the improvement effects of Ledebouriella seseloides (LS) ethanol extracts on lipid parameters in an ovariectomized animal model. Sixty, nine-week old female Sprague Dawley rats were randomly assigned to four groups as follows: sham-operated rats (SHAM), ovariectomized rats (OVX-CON) and ovariectomized rats that were treated with LS ethanol extracts (50 mg/kg/day and 200 mg/kg/day, respectively). The diets were fed to the rats for six weeks after their operation. The total-cholesterol and triglyceride contents on serum increased in the OVX-CON group compared to the SHAM group, but supplementation with the LS extract caused these factors to decrease. Notably, the serum LDL-cholesterol concentration in the supplemented 200 mg/kg/day LS ethanol extract group was significantly more reduced than the OVX-CON group. In addition, the platelet aggregation ability was lower in groups treated with LS than in the OVX-CON group. The alkaline phosphatase (ALP) activity was lower in the LS extract group compared to the OVX-CON group. Collagen content, in bone and cartilage, were reduced by ovariectomy, but the supplemented LS extract groups exhibited higher concentrations in their bones. According to these results, the improvement effects of LS extract on serum lipid parameters and osteogenesis in ovariectomized rats were illuminated.

• Korean Chemical Engineering Research
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• v.58 no.2
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• pp.176-183
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• 2020

In this study, synthesis of a hydrogel consisted of a coordination bond network between small organic molecules and transition metals had been carried out. By adding a tackifying material to the gel, the potential of the gel to be used as an adhesive material had been also confirmed. Synthesis of the adhesive had been done with simple mixing of 3 components: tannic acid, transition metal, and polymer. The tannic acid molecule possesses multiple hydroxyl groups that can form coordination bonds with the transition metals and hydrogen bonds with the hydrophilic polymers. Due to the morphology of the metal-organic complex and polymer dispersed in water, the fabricated material exhibited high adhesiveness and cohesiveness. Optimizing the rheological property had been conducted for use in adhesive by the synthesis with varying the transition metal (Fe³⁺, Ti⁴⁺), polymer, and treatment conditions. Rheological measurement results demonstrate the promising potential of the material as a bio-compatible and versatile pressure-sensitive adhesive with both high adhesiveness and cohesiveness.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.59 no.4
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• pp.413-426
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• 2014

This study was conducted to investigate changes of physicochemical properties and fatty acid compositions of rough rice stored at different storage temperatures and periods. So we analyzed texture, alkali digestion value (ADV), toyo glossiness value, pasting properties, fat acidity and fatty acid compositions of five rice varieties every 4 month on the condition of which rough rice had been stored at different temperatures (ambient and low temperature condition at $15^{\circ}C$) for 2 years. Hardness of cooked rice was increased by storage periods and cohesiveness of cooked rice was not considerably different among varieties according to storage temperatures and periods. ADV was significantly different among varieties and storage periods but not different with storage temperatures. Toyo glossiness value of cooked rice was continuously decreased from 4 months after storage regardless to storage temperature. The pasting properties were considerably affected by storage temperatures and periods of rough rice. Increase in peak viscosity, final viscosity and breakdown was observed but setback was decreased by storage periods. Fat acidity of brown rice was much higher than that of milled rice during storage of rough rice and tend to increase by storage period. Oleic acid among fatty acids of brown rice except Sindongin and Hitomebore tended to be decreased by storage periods and linoleic acid among fatty acids of brown rice of Hopum was decreased by storage periods. The contents of linoleinic acid and stearic acid among fatty acids of milled rice were comparatively decreased from 4 months after storage, whereas the content of palmitic acid tended to be increased by storage periods.

• Clinical and Experimental Pediatrics
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• v.48 no.6
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• pp.675-677
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• 2005

Pseudothrombocytopenia is usually associated with anticoagulant ethylene diaminetetraacetic acid (EDTA). The platelet clumping that occurs in EDTA-dependent pseudothrombocytopenia (EDPT) can sometimes be prevented by the use of other anticoagulants such as heparin or sodium citrate. As an alternative, we used kanamycin before or after the withdrawal of EDTA-anticoagulated blood in a 6-year-old boy with EDPT. Kanamycin used supplementarily during the differentiation of EDPT effectively prevented platelet clumping.