• Title/Summary/Keyword: 전신 방사선 조사

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Development of Total Body Irradiation Program (전신방사선조사 프로그램 개발)

  • Choi Byung Ock;Jang Ji Sun;Kang Young Nam;Choi Ihl Bohng;Shin Sung Kyun
    • Progress in Medical Physics
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    • v.16 no.3
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    • pp.130-137
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    • 2005
  • In total body irradiation (T81) for leukemia, we have a two methode. One is a AP (anterior-posterior) method and the other is a Lateral methode. Our hospital used lateral methode. T81 must consider about body contour, because of homogeneous dose distribution. For compensation about irregular body contour, we use compensator. For T81 treatment, we must be considered, accurate manufacture of compensator and accurate calculation of dose. We developed the automatic program for T81. This program accomplished for compensator design and dose calculation for irregular body. This program was developed for uses to use in a windows environment using the IDL language. In this program, it use energy data for each energy: TMR, output factor, inverse square law, spoiler, field size factor. This program reduces the error to happen due to the manual. As a development of program, we could decrease the time of treatment plan and care the patient accurately.

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전신방사선조사(TBI)시 다이오드측정기(Diode detector) 및 열형광선량계(TLD)를 이용하여 측정한 골조직 선량감쇠에 대한 고찰

  • 임현실;이정진;장인기;김완선
    • Journal of The Korean Radiological Technologist Association
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    • v.29 no.1
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    • pp.6-11
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    • 2003
  • 목적 : 전신방사선조사(TBI)시 균등한 선량을 조사할 목적으로 사용되는 각 신체부위별 보상체(compensator) 두께의 결정은 열형광선량계(TLD)를 이용하여 표면선량(surface dose)을 측정하고, 심부선량(depth dose)으로 환산하는 방법을 주로 이용한다. 그러나 이와 같은 방법은 골(bone) 조직에 대한 선량감쇠(dose attenuation)의 영향이 고려되지 않아 신체중심부에서의 정확한 심부선량을 알 수가 없다. 이에 본 연구

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'THE METHOD OF TBI FOR ACCURATE REPRODUCTION OF RADIATION FIELD AND PATIENT POSITION' (방사선 전신 조사 치료시 정확한 환자자세 및 조사야 재현을 위한 방법)

  • KWEON YOUNG-HO;LEE BYOUNG-GOO;WHANG WOONG-KU;KIM YOU-HYUN
    • The Journal of Korean Society for Radiation Therapy
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    • v.7 no.1
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    • pp.156-166
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    • 1995
  • Total body irradiation (TBI) requires large radiation field and extended source to axis distance (SAD), therefore in needs large size treatment room and it needs compensators which components. Appropriate thickness beam spoiler should be used to raise skin dose. Treatment machine, photon energy, total dose, dose rate, dose fractionation, patient position, shield of normal tissues and organs were known to important parameters for TBI. TBI disturbes regular daily treatment schedule and significantly overloads Radiation on oncology departments and during the treatment session it requires accurate reproduction of radiation field and patient position. We were enable to TBI in small size treatment room and short SAD with parallel opposing lateral fields technique and achieved homogenious whole body dose distribution using pb compensators and controled lung dose by lung shield blocks. Drawing a patient shadow on the wall, we could shortened set up time and possible to accurate reproduction of radiation field and patient position.

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Effects of Low-Dose Fractionated Total Body Irradiation on Murine Immune System (마우스에서 전신 저선량 분할 방사선 조사에 의한 면역학적 변화 평가)

  • Kim, Mi-Hyoung;Rhu, Sang-Young;Lim, Dae-Seog;Song, Jie-Young
    • Journal of Radiation Protection and Research
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    • v.39 no.3
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    • pp.134-141
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    • 2014
  • Along with the wide use of radiotherapy in cancer treatment, there is growing interest in beneficial effect of low-dose irradiation (LDI) in cancer therapy. Therefore, we investigate how LDI affects immune responses in mice model. Total body irradiation (TBI) on C57BL/6 mice was given at low-dose rate of $1mGy{\cdot}min^{-1}$ using $^{137}Cs$ source at three times for consecutive three days. Hematological examination, total cell numbers of spleen, populations and characteristics of splenocytes were determined. Total numbers of RBC or platelet in irradiated mice showed no significant changes. WBC counts were decreased in a dose-dependent manner 2 days after TBI, however, these differences are gradually waned until 28 days. Dose-dependent decrease in the number of splenocytes of TBI mice at day 2 was also improved as time progressed. While the level of Foxp3 mRNA was decreased, the frequency of $CD4^+$ T cells and $CD69^+$ cells in spleen was increased at day 2 and 14. Fractionated low-dose TBI on mice exhibited normal body weight with no distinguishable behavior during whole experimental periods. These results suggest that some parameters of immune system could be altered and evaluated by fractionated low-dose TBI and be used to broaden boundary of low dose radiation research.

Whole Lung Irradiation for Metastatic Lung Malignancy (전이성 폐암의 전폐 방사선치료)

  • Chung, Tae-Soo
    • Radiation Oncology Journal
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    • v.2 no.1
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    • pp.87-92
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    • 1984
  • The author reviewed four cases of multiple lung metastases who were treated by whole lung irradiation alone for palliation. All patients tolerated the treatment well without complication. Two patients who had symptoms from pulmonary metastases had subjective relief of symptoms and all four patients had objective regression of lung metastases on repeat chest X-rays. Present report and review of literature support that some selected patients with multiple lung metastases can be benefited by whole lung Irradiation. However, systemic chemotherapy should be main modality of treatment for this kind of disseminated disease whenever possible.

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Radioprotective Effect of Propolis on the Blood Corpuscle of a Mouse by SEM after X-irradiation on the Whole Body (전신 X-선 조사 후 마우스의 대동맥 혈구에서 SEM을 이용한 프로폴리스의 방사선방어효과 연구)

  • Ji, Tae-Jeong
    • Journal of radiological science and technology
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    • v.31 no.1
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    • pp.49-54
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    • 2008
  • After x-ray 5Gy radiation on the whole body of a mouse using a linear accelerator, its leucocyte, erythrocyte, and platelet were observed by SEM. Also, after injecting propolis into the abdominal cavity, the radio-protective effect of blood corpuscles was studied. The observation of micromorphology in blood corpuscles revealed that the number of leukocyte, erythrocyte, and thrombocyte decreased in the experimental group and the lump got together in blood corpuscles after 10 and 20 days. In RBC, crack or break on the surface and poikilosperocytes were observed. In the irradiation group, the size of leucocytes was smaller than that in control group and the number of villus at the verge substantially decreased. The blood corpuscles in the propolis group, however, had the similar results to control group.

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