• International Area Studies Review
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• v.15 no.3
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• pp.493-511
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• 2011

This study investigate the impacts of Chinese consumers' cultural dispositions on the WOM behaviors in SNS. Specifically, cultural dispositions in the individual-level, collectivism and uncertainty avoidance, were examined as potential predictors of eWOM behaviors in SNSs. Hypotheses are tested with a sample of 164 university students in Shanghai, China. The results of the structural equation analysis reveal that chinese consumers' collectivism in the individual-level positively affects the opinion seeking behavior. And chinese consumers' uncertainty avoidance in the individual-level positively affects the opinion seeking behavior and negatively affects the opinion giving behavior. Lastly, the opinion giving behavior positively affects the pass along behavior. Theoretical and managerial implications for Internet marketers in China were presented and discussed.

• Journal of Life Science
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• v.29 no.1
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• pp.105-111
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• 2019

In recent years, progress has been made in the search for the development of new anti-cancer agents by employing specific inhibitors of histone deacetylase (HDAC)-6 to block signal transduction pathways in cancer cells. This study examined the effects of tubastatin A (TubA), an HDAC-6 inhibitor, on the growth and development of immature oocytes in murine ovaries using RNA sequencing analysis. The results from a gene set enrichment analysis (GSEA) indicated that the expression of most of the gene sets involved in the cell cycle and control and progression of meiosis decreased in the TubA-treated group as compared with that in germinal vesicle (GV) stage oocytes. In addition, an ingenuity pathway analysis (IPA) suggested that TubA not only caused increased expression of p53 and pRB and decreased expression of CDK4/6 and cyclin D but also caused elevated expression of genes involved in the control of the DNA check point in G2/M stage oocytes. These results suggest that TubA may induce cell cycle arrest and apoptosis through the induction of changes in the expression of genes involved in signal transduction pathways associated with DNA damage and the cell cycle of immature oocytes in the ovary.

• Korean Journal of Poultry Science
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• v.50 no.4
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• pp.283-291
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• 2023

Long-chain fatty acids (LCFAs) are vital in cellular compartments, primarily regulating lipid metabolism. Fatty Acid-Binding Proteins (FABPs) facilitate LCFA transport, lipid synthesis, storage, and act as signaling molecules influencing various pathways, including inflammation. FABP4, in particular, is linked to vascular and cardio-related diseases, and it plays a role in macrophage-mediated inflammatory responses. Previous studies have identified FABP4 as not only a representative biomarker for lipogenesis but also as having correlations with immune responses. This study aims to investigate the regulation of the chicken FABP4 (chFABP4) gene by toll-like receptor 3 (TLR3) activation and determine the signaling pathways that are involved in chFABP4 transcriptional regulation. We analyzed the transcriptional regulation of chFABP4 in TLR3-stimulated DF-1 cells. The results showed that chFABP4 was up-regulated upon stimulation with polyinosinic-polycytidylic acid (PIC), a TLR3 ligand. Notably, chFABP4 transcription was independently regulated in the NF-κB signaling pathway. It was up-regulated in p38 inhibition, demonstrating that the p38 signaling pathway might suppress the transcription of chFABP4 within TLR3-activated DF-1 cells. In contrast, chFABP4 expression was down-regulated in JNK signaling pathway inhibition, suggesting the positive regulation of JNK signaling pathway for chFABP4 transcription in DF-1 cells in response to TLR3 activation, consistent with findings in macrophages. MEK pathway inhibition resulted in a similar regulation to NF-κB signaling. These results suggest that each MAPK contributes differentially to the transcriptional regulation of chFABP4 by in DF-1 cells in response to TLR3 activation.

• The Journal of the Acoustical Society of Korea
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• v.16 no.6
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• pp.100-105
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• 1997

To analyze the multipath propagation effects on the source bearing detection of HLA(Horizontal Line Array), the conversion mechanism of the multipath into the bearing is described, and the bearing is estimated from the multipath modeled with typical sound velocity structures of the East and the South Sea of Korea. The erroneous bearing is observed from the beamforming outputs simulated with the modeled multipath, and the erroneous phenomena are analyzed. In case of the East Sea, since the multipath propagation with a high receiving angle occurs due to strong inverse slope of the sound velocity structure, it is possible that the estimated source bearing is different from the real source bearing, and that the number of the source is misrecognized.

• Journal of the Korea Society for Simulation
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• v.19 no.3
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• pp.1-6
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• 2010

Simulation analysis may be the essential means to either evaluate performance of systems or optimize system parameters for new design. Including many variations for design and implementation, MANET (Mobile Ad-hoc NETwork) is one target area of such an analysis. Since every node, however, included in the network has mobility, one MANET could be overlapped or merged with another one which use a different transport protocol. In order to communicate among nodes in this case, the new merged network should configure paths and addresses in advance. Configuring paths and addresses generates much overheads which ultimately cause delay in communicating data. Performance analysis is required to improve the data transport performance by minimizing overheads. This paper proposes a sound address auto-configuration method which is based on an on-demand manner and then presents modeling and performance analysis of the method. NS-2 simulation results verify that the proposed method can not only alleviate overheads, which are inevitably generated for address auto-configuration processes, and but also decentralize them in time.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2009.10a
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• pp.591-592
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• 2009

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2008.11a
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• pp.295-296
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• 2008

• Electronics and Telecommunications Trends
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• v.12 no.1 s.43
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• pp.1-13
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• 1997

OSF/1 AD 운영체제에 사용된 노드간 메시지 전달 기법인 DIPC(Distributed Interprocess Communication)는 마이크로커널 내에 구현된 서브시스템으로, 다중 컴퓨터 환경에서 특정 태스크간의 통신을 효과적으로 지원할 수 있도록 설계되었다. 본 문서에서는 이러한 DIPC 서브시스템을 그 운영특성을 중심으로 자세히 살펴보았다.

• Proceedings of the Korea Information Processing Society Conference
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• 2001.04b
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• pp.1209-1212
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• 2001

본 논문에서는 PCB(Printed Circuit Board)회로에서 고속 신호들을 전달하는 배선의 특성 및 배선의 요구사항에 의한 설계 규칙과 이론화된 공식은 이용하여 PCB상에 배치되는 부품들간의 배선경로를 추적하여 해당 배선의 특성을 분석하고, 흐르는 신호의 특성 및 해당 신호의 전기/전자적인 시뮬레이션을 수행할 수 있도록 하는 PCB회로의 신호통합 시뮬레이터에 대하여 언급하고 실험을 통하여 시뮬레이션의 타당성을 검증하였다.

• 기계와재료
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• v.23 no.3
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• pp.190-198
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• 2011

하이브리드 굴삭기는 에너지 재생 및 연비향상을 위하여 기존의 유압부품들 중 일부를 전기부품으로 대체하여 시스템을 구성하고 있다. 따라서, 하이브리드 굴삭기의 신뢰성을 평가하고 보장하기 위해서는 기계적인 부하와 전기적인 부하가 복합적으로 영향을 미쳐 발생되는 고장모드를 고려하여 신뢰성평가기법을 개발하여야 한다. 특히 하이브리드 굴삭기는 가혹한 실외 환경조건에서 운용되므로 새롭게 개발되는 부품들에 대하여 설계 결함을 조기에 발견하기 위한 복합 내환경 시험과 초가속 수명시험이 수행되어야만 한다. 본 연구에서는 FMEA, FMECA, FTA 및 HALT 등의 다양한 신뢰성 기법을 사용하여 하이브리드 굴삭기의 신뢰성평가기법을 개발하였고, 개발대상 하이브리드 굴삭기의 주요 동력전달 파트인 선회구동 시스템에 대한 신뢰성평가장비를 개발하고 구축하였다. 본 연구에서 개발된 하이브리드 굴삭기 신뢰성평가기법은 하이브리드 자동차의 부품들에 대한 신뢰성평가에도 유용하게 사용될 수 있을 것으로 기대된다.