• The Microorganisms and Industry
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• v.16 no.1
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• pp.18-20
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• 1990

현재 전세계적으로 10,000여개 이상의 실험실에서 생물공학적인 연구가 진행중에 있고, 200여개 이상의 회사에서 생물공학을 이용한 제품이 만들어지고 있다.(Saftlas, 1984). 이와같은 제품으로 생물농약(예, 모기억제에 사용되는 Bacillus thuringiensis var. israelensis 등)이라든가 insulin, 성장호르몬, lymphotoxin및 항암제등의 의약품(Saftlas, 1984)과 식물품종개량제(예, 질소 공정의 vector로 사용되는 Agrobacterium tumerfaciens의 Ti Plasmid)(McDanial, 1981 ; Shaw, 1986) 등이 있다. 그러나 최근 미생물 생태분야에서는 이와같이 만들어진 미생물들 (genetically engineered microorganisms : GEMs)이 자연 생태계에 유출되었을때 야기될 가능성이 있는 biohazaed에 대하여 관심이 집중되고 있다. (Curtiss, 1976 ; Sharples, 1983 ; Rissler, 1984). 토양환경에서 GEM이 유전물질을 전달항 수 있는 기작은 크게 conjugation, transduction, transformation 등이 알려지고 있다. 여기서는 주로 토양환경에서 transformation에 의한 유전물질의 전달과정에 대한 최근 연구동향을 간단히 기술하고자 한다.

• Journal of Power System Engineering
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• v.9 no.1
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• pp.42-49
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• 2005

The vibration analysis of a rectangular plate with stiffeners is formulated by using the transfer stiffness coefficient method (TSCM). This method is based on the concept of the successive transmission of stiffness coefficients which are defined as the relationship between the force vector and the displacement vector at an arbitrary nodal line. In order to confirm the validity of the present method, bending vibration analysis for a rectangular plate with stiffener is carried out on a personal computer by using the present method and the finite element method (FEM). Through comparing computational results of the TSCM and the FEM, the effectivness of the TSCM from the viewpoint of computational cost, that is, computational time and storage is demonstrated.

• Journal of KSNVE
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• v.7 no.5
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• pp.853-860
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• 1997

For this study, the multi-degree of freedom analysis model of torsional vibration was developed. This model is combined with mass moment of inertia and torsional spring in two wheel drive and four wheel drive vehicle. We compared and analyzed torsional vibration characteristics by natural frequencies and mode shapes which are obtained by free vibration analysis of this model. And we studied torsional vibration contribution of driveline elements by performing the forced vibration analysis of engine excitation torque. The validity of this model is demonstrated by the field test. The reduction effect of the torsional vibration along the driveline design factor is presented by the analytical results.

• Journal of the KSME
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• v.25 no.4
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• pp.295-303
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• 1985

경량화와 저연비의 추세에도 불구하고 자동화의 안락감에 대한 고객의 요구 수준은 더욱 높아 가고 있다. 따라서 이와 같은 승차감을 대표하는 요소의 실내소음은 여전히 상품 평가의 중요한 지표가 되고 있으며 최근 이 방면의 기술 역시 요구에 상응하는 속도로 발전하고 있다. 모든 기계 요소의 소음의 수준은 곧 개개의 부품에 대한 완벽성을 총체적으로 평가하는 수단이며 이는 발생원, 전달계, 응답계등 모든 측면에서의 기술 수준을 대변한다. 최근 컴퓨터와 수치 해석법 그리고 실험장치의 발달에 힘입어 이들 각각에 대한 보다 신속하고 정확한 저감대책 수립은 물론 상호간의 연성 문제까지를 포함한 해석이 가능해 지고 있으며 이를 이용한 저소음 차량 개발 노력이 경주되고 있다. 자동차 보유 댓수가 급격히 증가 되고 있는 국내 여건은 물론 자동차 산업이 수출 전략적 측면에서의 위치를 굳히고 있는 현시점에서 생활공간의 일부인 자동차의 실내소음 저감에 더욱 많은 연구발전이 있기를 기대한다.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1993.04a
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• pp.119-119
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• 1993

안트라싸이클린계 항암항생제의 부작용 발생기전으로는 C-고리의 퀴논 부위에 전자가 전달되어 퀴논 고리가 환원되는 과정이 제시되고 있으며 그 중 하나의 전자가 전달되어 생성되는 활성산소(activated oxygen)가 심장독성과 관련이 있는 것으로 알려져 있다. 이 때 퀴논 고리의 환원력(전자흡수능력)이 C-고리자체의 변환, 또는 인접 B-고리에 도입된 치환체의 영향으로 억제될 수 있다는 보고를 이론적 근거로 하여 안트라싸이클리논 골격을 전자흡수 능력을 가진 acridone 골격으로 치환한 화합물(1)과 안트라싸이클리논 골격을 유지하면서 aminosugar 부위를 pentopyranose계열을 도입 한 2 합성하였다. 화합물 1은 1,3-butadiene 과 1,4-benzoquinone 의 Diels-Alder adduct 3을 출발물질로 하여 7 단계의 반응과정으로 합성하였다.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.12 no.9
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• pp.674-684
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• 2002

In order to decrease remarkably the computation time and storage used in the direct integration method without the loss of accuracy, authors suggest a new transient analysis algorithm. This algorithm is derived from the combination of three techniques, that is, the transfer technique of the transfer stiffness coefficient method, the modeling technique of the finite element method, and the numerical integration technique of the Newmark method. In this paper, the transient analysis algorithm of a frame structure is formulated by the proposed method. The accuracy and computation efficiency of the proposed method are demonstrated through the comparing with the computation results by the direct integration method for three computation models under various excitations.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.14 no.8
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• pp.749-756
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• 2004

While designing shafting in reciprocating machines with internal combustion engines which derive generators, pumps, and vehicles, it is very important to calculate the additional stress of shafting by torsional vibration. In this paper, the transfer stiffness coefficient method which is based on the successive transfer of stiffness coefficient was applied to the calculation of the additional stress of shafting in reciprocating machine by torsional vibration. In order to confirm the effectiveness of the present method, a propulsion shafting with a diesel engine in a vessel was considered as the computational example of shafting in reciprocating machine. The results calculated by the present method were compared with those of the modal analysis method, the mechanical impedance method, and free vibration analysis.

• Transactions of the Korean Society of Automotive Engineers
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• v.5 no.1
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• pp.69-78
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• 1997

Main sources of the vibration in gear driving system are transmission error and backlash. Transmission error is the difference of the rotation between driving and driven gear due to tooth deformation and profile error. Vibro-impacts induced by backlash between meshing gears lead to excessive vibration and noise in many geared rotation systems. Nonlinear dynamic characteristics of the gear driving system due to transmi- ssion error and backlash are investigated. Transmission error is calculated for spur gear. Nonlinear equation of motion for the gear driving system is developed with the calculated transmission error and backlash. Numerical analysis of the equation and the experimental results show the existence of meshing frequency, superharmonic compon- ents. Instability of the gear driving motion is found on the basis of Mathieu equation. Rattle vibration due to backlash is also discussed on the basis if nonlinear jump phenomenon.

• Transactions of the Korean Society of Automotive Engineers
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• v.4 no.1
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• pp.63-74
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• 1996

Automatic transmission for heavy duty vehicles is a part of the power pack which includes steering and braking systems. This transmission in different from the one for passenger car. Therefore, in order to understand the trend of the important design parameters, maneuverability, acceleration performance and maximum speed, we need to analyze the total performance characteristics of the power transmission systems. In this study, modeling of the automatic transmission in heavy duty vehicle is carried out and the performance analysis method is presented. Results can be used for performance estimation data in the analysis for several combination method which determines the optimal parameters on the basis of penalty functions and weightings. And the estimation method of the important performance parameters such as engine inertia or power loss of engine by experiments is presented.

• Transactions of the Korean Society of Automotive Engineers
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• v.3 no.2
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• pp.102-111
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• 1995

The non-periodic fluctuation of the engine torque appears to be the major source of the torsional vibration of the automotive driveline. The reduction of this torsional vibration has become a significant problem along with the requirements of higher performance. The torsional vibration of the automotive driveline can be reduced by smoothing the fluctuation by adjusting the torsional characteristics of the clutch-disc. Computer simulation of the driveline is a useful investigative tool on studying the torsional characteristics of the clutch-disc. In this paper, a dynamic model for the automotive driveline was developed, and the engine torque of the model were evaluated with experimental data. By executing a simulation using the model, it has become possible to obtain the clutch-disc torsional characteristics for reducting the torsional vibration at creeping.