• Title/Summary/Keyword: 전달경로분석법

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Analytical trends in mass spectrometry based metabolomics approaches of neurochemicals for diagnosis of neurodegenerative disorders (퇴행성신경질환의 진단을 위한 신경전달물질 대사체의 질량 분석법 동향)

  • Lee, Na-Kyeong;Jeon, Won-Jei;Jeong, Seung-Woo;Byun, Jae-Sung;Lee, Wonwoong;Hong, Jongki
    • Analytical Science and Technology
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    • v.30 no.6
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    • pp.355-378
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    • 2017
  • Because neurochemicals are related to homeostasis and cognitive and behavioral functions in human body and because they enable the diagnosis of numerous neurodegenerative disorders, there has been increasing interest in the development of analytical platforms for neurochemical profiling in biological samples. In particular, mass spectrometry (MS)-based analytical methods combined with chromatographic separation have been widely used to profile neurochemicals in metabolic pathways. However, development of delicate sample preparation procedures and highly sensitive instrumental detection is necessary considering the trace levels and chemical instabilities of neurochemicals in biological samples. Therefore, in this review, analytical trends in MS-based metabolomics approaches to neurochemicals in multiple biological samples, such as urine, blood, CSF, and biological tissues, are discussed. This paper is expected to contribute to the development of an analytical platform to discover biomarkers that will aid diagnosis, prognosis, and treatment of neurodegenerative disorders.

A Study on Contribution Analysis using Operational Transfer Path Analysis based on the Correlation between Subjective Evaluation and Zwicker's Sound Quality Index for Sound Quality of Forklifts (지게차의 주관적 음질평가와 Zwicker 음질지수의 상관관계 및 전달경로분석법(OTPA)을 활용한 음질 기여도 분석)

  • Kim, Beom Soo;Yang, Soon Yong
    • Journal of Drive and Control
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    • v.13 no.2
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    • pp.19-25
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    • 2016
  • Recently, drivers have begun to regard comfort in the cabin as one of the most important factors in construction equipment like forklifts. Accordingly, it has become more important to design a forklift cabin with a better sound quality as well as lower sound level, which can make a driver more comfortable. In this paper, the correlation between subjective evaluation and Zwicker's sound quality index was analyzed through a blind test by a few workers in forklifts and other construction equipment in several countries. Correlation analysis showed that Loudness and Sharpness were ranked in sequence, and tendencies were different from country to country. Also, contribution analysis for Loudness and Sharpness using operational transfer path analysis (OTPA), which is widely used in the field of noise, vibration, and harshness (NVH), was performed. However, Loudness and Sharpness cannot be used with OTPA directly because there are no linear relationships between the sources and receivers. In this paper, both are calculated by applying the DIN 45631 method with a contribution rate (%) of 1/3 Octave Sound Pressure Level by OTPA method in addition to considering spectral masking.

Experimental Study on the Power Flow Analysis of Vibration of a Plate (평판 진동 해석에 대한 파워흐름해석법의 실험적 연구)

  • Lee Byoung-Chul;Kil Hyun-Gwon;Lee Hyo-Haeng;Lee Yong-Hyun;Hong Suk-Yoon
    • Proceedings of the Acoustical Society of Korea Conference
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    • autumn
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    • pp.327-330
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    • 2004
  • 파워흐름해석법은 진동에너지 흐름 형태에 따른 에너지지배방정식을 이용하는 방법으로서, 진동에너지의 공간적인 분포와 전달 경로 등을 제시할 수 있는 방법이다. 이러한 파워흐름해석법은 고주파수 대역의 진동을 해석하기 위하여 효과적으로 적용될 수 있다. 본 연구에 서는 평판 구조물 진동에 대한 파워흐름해석법의 예측 결과를 실험 결과와 비교하여 분석하였다. 분석할 진동 특성들은 손실계수, 주파수 응답함수 등을 포함한다. 그리고 이러한 분석 결과로부터 파워흐름해석법이 고주파수 진동에 효과적으로 적용될 수 있음을 보였다.

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A Study on the Improvement of the Sound Quality of the Interior Noise of A/T Vehicle in Idle State (공 회전시 자동변속기 차량의 실내소음 음질 개선에 관한 연구)

  • 이상권;최병욱;여승동
    • Transactions of the Korean Society of Automotive Engineers
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    • v.1 no.1
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    • pp.110-119
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    • 1993
  • 본 논문은 자동변속기를 탑재한 차량에서 에어콘(air condition)을 작동시키고, 공 회전시 기어의 변속을 "D"단에 두었을 때 실내에서 발생하는 이상음의 원인규명 및 해결 방 법에 관한 연구 결과를 논하고자 한다. 이 이상한 소음의 원인을 규명하기 위하여 실린더 내부의 연소압력, 메인 베어링캡(main bearing cap)의 진동, 엔진 마운팅 보스의 진동 및 차 량의 실내소음을 동시에 측정하여 분석하였으며 이 결과에 의하면 이상음의 원인은 크랭크 샤프트(crank shaft)의 굽힘진동이 파워플랜트(power plant)를 가진하여 진동을 증가시키고, 이 진동이 마운팅 보스를 통하여 차량의 차체에 전달되며, 차체의 진동에 의해서 발생하는 고체 전달음(structure-borne noise)이었다. 또한 이상음의 주기는 주파수 성분은 200-400Hz 이었다. 이 이상음은 크랭크 샤프트의 댐퍼 풀리의 질량을 저감하여 크랭크 샤프트의 동특 성을 개선함으로서 해결가능하고, 혹은 점화시기를 지연하여 연소 압력을 낮춤으로서 해결 가능하다.

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Road Noise Estimation Based on Transfer Path Analysis Using a Simplified Tire Vibration Transfer Model (단순화된 타이어 진동전달 모델의 전달경로분석법을 이용한 로드노이즈 예측기술 개발)

  • Shin, Taejin;Park, Jongho;Lee, Sangkwon;Shin, Gwangsoo;Hwang, Sungwook
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.23 no.2
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    • pp.176-184
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    • 2013
  • Quantification of road noise is a challenging issue in the development of tire noise since its transfer paths are complicated. In this paper, a simplified model to estimate the road noise is developed. Transfer path of the model is from wheel to interior. The method uses the wheel excitation force estimated throughout inverse method. In inversion procedure, the Tikhonov regularization method is used to reduce the inversion error. To estimate the wheel excitation force, the vibration of knuckle is measured and transfer function between knuckle and wheel center is also measured. The wheel excitation force is estimated by using the measured knuckle vibration and the inversed transfer function. Finally interior noise due to wheel force is estimated by multiplying wheel excitation force in the vibro-acoustic transfer function. This vibro-acoustic transfer function is obtained throughout measurement. The proposed method is validated by using cleat excitation method. Finally, it is applied to the estimation of interior noise of the vehicle with different types of tires during driving test.

An Efficient Channel Estimator for OFDM-CDMA Systems in Fading Channels (감쇄채널 환경에서 직교 주파수 분할 다중화-부호분할 다중접속 시스템을 위한 효율적 채널 추정기)

  • 정혜정;김형명
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.26 no.8A
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    • pp.1298-1310
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    • 2001
  • 이 논문에서는 채널 상태가 천천히 변할 때, 직교 주파수 분할 다중화-부호분할 다중접속 시스템에 적합한 채널 추정 방법을 제안하고 성능을 분석한다. 제안한 채널 추정 방법은 시간과 주파수 영역 모두에 파일럿 심볼을 삽입하고, 이산 퓨리에 변환 후 영을 채워 넣는 방법을 이용한 내삽법으로 모든 부채널의 전달 함수를 얻는다. 또한 변환 영역에서 저대역 여파를 통해 받은 파일럿 신호에 존재하는 가산성 백색 정규 잡음의 영향을 상당히 줄일 수 있다. 이 때 저대역 여파기의 차단 주파수는 채널의 다중경로 수에 따라 정해진다. 같은 방법을 이용한 내삽법을 시간축으로 적용하여 시간에 따라 변하는 부채널의 채널 응답을 얻을 수 있다. 이 논문에서는 여러 가지 내삽법에 대한 평균 제곱 오차 성능을 수식적으로 제시한다. 제안한 저대역 여파를 결합한 내삽법을 쓰면 채널의 통계적 특성에 관한 정보 없이, 그리고 훨씬 적은 계산량으로 선형 최소 평균 제곱 오차 추정기와 비슷한 성능을 얻는다. 레일리 감쇄 채널에 대한 모의 실험을 통해 같은 비트 오류율에 대한 신호 대 잡음 비의 이득이 있음을 보인다.

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Implementation and Simulation of 2D Ray-tracing Technique in Multiple-wall Indoor Environment (다중 벽면 구조의 실내 환경에서 2차원 광선추적법 구현 및 시뮬레이션)

  • Jeong, Seung-Heui;Kang, Chul-Gyu;Oh, Chang-Heon
    • Journal of Digital Contents Society
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    • v.8 no.4
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    • pp.459-465
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    • 2007
  • In this paper, we implemented a ray-tracing simulator with a ray-launching technique and generated the propagation path of each ray in a multiple-wall indoor environment. In this simulator, we adopted two dimension ray-tracing techniques considering the reflection and penetration were dominant propagation factor in the indoor channel. From the result, we verified that this ray-tracing simulator shows the similar path pattern and delay distribution with the experiment results of the previous research. Especially, impulse responses of the ray were corresponding to reference result in non-line of sight of multiple-wall indoor environment. Furthermore, we confirmed that channel profiles having respectively different departure angle 1 degree to 7 degree were similar between them.

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Interior Noise Reduction of Wheel Loader Using Transfer Path Analysis and Panel Contribution Analysis (전달 경로 분석과 패널 기여도 분석을 이용한 휠로더의 실내소음 저감에 관한 연구)

  • Kim, Bo-Yong;Shin, Chang-Woo;Jeong, Won-Tae;Park, Sung-Yong;Jang, Han-Kee;Kim, Seong-Jae;Kang, Yeong-June
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.18 no.8
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    • pp.805-815
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    • 2008
  • Transfer path analysis(TPA) and panel contribution analysis(PCA) have been used widely to reduce interior noise of mechanical systems. TPA enables us to decompose interior noise into air-borne and structure-borne noises and estimate the path contribution of noise sources. PCA is also used to identify the noise contribution of each sub-panel in vibro-acoustic systems. In this paper, TPA and PCA are applied to wheel loader, one of the heavy construction equipments. Firstly, TPA for air-borne noise is conducted to estimate the contribution of air-borne sources using pressure transfer function. Thereafter, TPA for structure -borne noise is employed to verify the results of air-borne source quantification through the synthesis of two results. Secondly, PCA is performed by both TPA using pressure transfer function between panels inside the cabin and boundry element method(BEM) for the cabin of wheel loader with various boundary conditions. As a results, it was found that TPA conducted by experiments and PCA accomplished by both experiments and BEM are very effective methods in analyzing the path and contribution of the noises for reducing an interior noise level in the wheel loader system.

Implementation and Evaluation of 2D Ray-Tracing Technique for Indoor Propagation Characteristics Modeling (실내 전파특성 모델링을 위한 2차원 광선추적법 구현 및 평가)

  • Jeong, Seung-Heui;Kang, Chul-Gyu;Oh, Chang-Heon
    • Journal of Advanced Navigation Technology
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    • v.11 no.4
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    • pp.454-460
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    • 2007
  • In this paper, we implemented a ray-tracing simulator with a ray-launching technique and generated the propagation path of each ray in an multiple-wall indoor environment. In this simulator, we adopted two dimension ray-tracing techniques considering the reflection and penetration were dominant propagation factor in the indoor channel. From the result, we verified that this ray-tracing simulator shows the similar pattern and delay distribution with the experiment results of the previous research.

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A Study on Interior Noise Contribution Analysis of Trains based on OTPA Method (OTPA방법을 이용한 철도차량 실내 소음 기여도 분석 연구)

  • Jung, Jae-Deok;Hong, Suk-Yoon;Song, Jee-Hun;Kwon, Hyun-Woung;Noh, Hee-Min;Kim, Jun-Kon
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.26 no.1
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    • pp.97-103
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    • 2016
  • The sensitivity of interior noise that the passengers perceive is comparatively high in the train, and structure-borne and air-borne types of noises come into the train. In this paper, to analyze contributions of these noise sources operational transfer path analysis(OTPA) is used. OTPA has some advantages of executing the contribution rates of several sources simultaneously, and in this work, 29 points are measured while running. Transfer functions between reference measurement points and response measurement points are calculated by the singular value decomposition(SVD) and Principal component analysis(PCA) method, and the frequency characteristics of the noise source are successfully derived. Also the interior noise is predicted and compared with measurement data to show the reliability.