• Title/Summary/Keyword: 전남대학

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Biochemical Assessment of Deer Velvet Antler Extract and its Cytotoxic Effect including Acute Oral Toxicity using an ICR Mice Model (ICR 마우스 모델을 이용한 녹용 추출물의 생화학적 평가 및 급성 경구 독성을 포함한 세포 독성 효과)

  • Ramakrishna Chilakala;Hyeon Jeong Moon;Hwan Lee;Dong-Sung Lee;Sun Hee Cheong
    • Journal of Food Hygiene and Safety
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    • v.38 no.6
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    • pp.430-441
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    • 2023
  • Velvet antler is widely used as a traditional medicine, and numerous studies have demonstrated its tremendous nutritional and medicinal values including immunity-enhancing effects. This study aimed to investigate different deer velvet extracts (Sample 1: raw extract, Sample 2: dried extract, and Sample 3: freeze-dried extract) for proximate composition, uronic acid, sulfated glycosaminoglycan, sialic acid, collagen levels, and chemical components using ultra-performance liquid chromatography-quadrupole-time-of-light mass spectrometry. In addition, we evaluated the cytotoxic effect of the deer velvet extracts on BV2 microglia, HT22 hippocampal cells, HaCaT keratinocytes, and RAW264.7 macrophages using the cell viability MTT assay. Furthermore, we evaluated acute toxicity of the deer velvet extracts at different doses (0, 500, 1000, and 2000 mg/kg) administered orally to both male and female ICR mice for 14 d (five mice per group). After treatment, we evaluated general toxicity, survival rate, body weight changes, mortality, clinical signs, and necropsy findings in the experimental mice based on OECD guidelines. The results suggested that in vitro treatment with the evaluated extracts had no cytotoxic effect in HaCaT keratinocytes cells, whereas Sample-2 had a cytotoxic effect at 500 and 1000 ㎍/mL on HT22 hippocampal cells and RAW264.7 macrophages. Sample 3 was also cytotoxic at concentrations of 500 and 1000 ㎍/mL to RAW264.7 and BV2 microglial cells. However, the mice treated in vivo with the velvet extracts at doses of 500-2000 mg/kg BW showed no clinical signs, mortality, or necropsy findings, indicating that the LD50 is higher than this dosage. These findings indicate that there were no toxicological abnormalities connected with the deer velvet extract treatment in mice. However, further human and animal studies are needed before sufficient safety information is available to justify its use in humans.

The color stability and antibacterial of provisional polyethyl methacrylate (PEMA) resin with zirconia nanoparticles (지르코니아 나노입자 첨가된 PEMA (Polyethyl Methacrylate)레진 표면의 색안정성 및 항균평가)

  • Kim, Hee-Seon;Lee, Seon-Ki;Jang, Woohyung;Park, Chan;Lim, Hyun-Pil
    • Journal of Dental Rehabilitation and Applied Science
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    • v.38 no.1
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    • pp.18-25
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    • 2022
  • Purpose: This study aimed to evaluate the color stability and antibacterial properties of the surface of polyethyl methacrylate (PEMA) resin with zirconia nanoparticles added. Materials and Methods: The control group was pure PEMA resin, and the experiment group was PEMA resin 15 mm in diameter and 2.5 mm in thickness disk-shaped specimens with 2, 4 and 8 w/v% of zirconia nanoparticles added, which were respectively divided into Group Z2, Group Z4, and Group Z8. After analyzing the surface roughness and color stability of the specimens, their antibacterial properties were evaluated using Porphyromonas gingivalis (P. gingivalis). The Statistical analysis was performed using when normality was met in the Shapiro-Wilk test, one-way ANOVA was used to test parameters, and Tukey's test was used as a post hoc test. When normality was not met, the Kruskal-Wallis test, a non-parametric test was used (P < 0.05). Results: The surface roughness measurement found that there was no significant difference between the experimental and control groups. The color stability evaluation showed that the Z2, Z4, and Z8 groups were within the color range of natural teeth. The adhesion of P. gingivalis was evaluated to be significantly reduced in Group Z2 compared to the control group (P < 0.05). In the Z2 group, Z4 group, and Z8 group, dead cells bacteria than the control group were observed. Conclusion: In conclusion, PEMA resin with zirconia nanoparticles added was within the range of natural teeth in color and reduced the adhesion of P. gingivalis.

Oral Health and Stress of College Women in Some Areas (일부지역 여대생의 스트레스와 구강건강)

  • Kim, Seo-Yeon;Lee, Jae-Ra;Choi, Moon-Sil
    • Journal of dental hygiene science
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    • v.15 no.4
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    • pp.503-508
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    • 2015
  • The purpose of this study was to examine factors related to the oral health by stress in college women. This survey was conducted between June 16, 2014 and July 18, 2014 to investigate the correlation between stress and oral health Data were obtained from 393 women students of 5 colleges in Gwangju and Jeollanam-do. The oral health of college students is related with the stress which has a correlation between oral condition satisfaction(-) and inconvenient(+) of mastication and pronunciation (p<0.01). Also, factors affecting stress are discomfort during mastication and oral state satisfaction and discomfort during mastication. The discomfort during mastication showed the highest stress while the higher status of oral satisfaction showed lower stress (p<0.05). Therefore, college women stress is related with oral health. Colleges should consider developing a program which can appropriately manage and regulate stress to relieve their stress.

Comparison between Japan, China, and Korea on How Parents with a Toddler Feel about Food Safety (일본, 중국, 한국 영유아 부모의 식품 안전에 대한 인식 비교)

  • MIZUNO, Tomomi;CHO, Hong-Joong;QU, GuoFeng;TOKUDA, Katsumi
    • Journal of Digital Convergence
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    • v.16 no.12
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    • pp.641-646
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    • 2018
  • Purpose : The aim of this research was to clarify the difference in awareness of food safety and what they feel as dangerous among parents in Japan, China, and Korea and how they are different among the nations. Methods : Research subjects were 250 parents in Japan, 181 parents in China, 166 parents in Korea whose children attend a child institution or a day care center. We conducted a questionnaire survey that was self-written and anonymous. Results : Parents in Japan feel safer than Korea and China, and parents in Korea feel safer than China about food that are sold generally. Especially, in China, the average of 5 level scale was lower than the median so it shows that people do not trust food that are sold in the market. All 3 countries tend to have the awareness that "pesticide that is over the standard amount is detected from vegetables in China" and "vegetable grown without pesticides and organic produce are safe" and showed no significant difference. Also, there was a significant difference statistically for the awareness that "it makes it easier to get cancer if you eat food that contain radiation" and "there is a possibility that seafood caught near Japan contain radiation". Parents in Japan emphasize that "the price is low" the most and it was significantly higher than in China and Korea. Also, similar to parents in Japan, parents in Korea tend to emphasize that it is "domestic". On the other hand, it verified that parents in China emphasized "the meat or fish is grown without antibiotics" and "it uses vegetable grown without pesticides".

Affiliated with the Department of Beauty in Gyeongsang-do and Jeolla-do and trend analysis of department names (영호남 소재 대학 미용학과의 소속 계열 및 학과명에 대한 동향 분석)

  • Park, Jang-Soon
    • Journal of the Korea Convergence Society
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    • v.12 no.4
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    • pp.311-316
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    • 2021
  • The college's beauty department, which has a globalized education system that breaks away from the uniform beauty concept, can dominate in the fierce competition with other schools, and the development and vitalization of the department is guaranteed. In addition, research on the department name is very necessary to establish internal and external PR strategies for affiliated departments and departments and to analyze the direction of realistic beauty education. Accordingly, as a result of analyzing the trends of the department and department name by classifying the universities in Yeonghonam into four regions, the departments belonging to each region of the beauty department showed the most belonging to the natural science and arts and sports departments. In addition, the names of beauty departments by region are Busan and Gyeongnam, Daegu and Gyeongbuk, Gwangju and Jeonnam, and Jeonbuk with 5 beauty departments (29.41%), 3 beauty design schools (13.04%), and 8 beauty and beauty departments. (50.00%), beauty design departments, 2 schools (33.33%). This study makes it possible to cultivate professional beauticians who cultivate an artistic and creative sense that meets the educational goals of beauty education, and it is expected that it will be provided as a very necessary basic data for the division of departments or change of department name according to detailed majors.

Improving the reliability of Certificate bodies of Environmentally-Friendly Agricultural Products (친환경농산물 인증기관의 신뢰도 제고방안 - 민간인증기관 설문조사 결과를 바탕으로 -)

  • Shin, Y.K.;Park, J.K.
    • Journal of Practical Agriculture & Fisheries Research
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    • v.17 no.1
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    • pp.113-124
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    • 2015
  • The purposes of this study is to draw up some measures for improving the reliability of certificate bodies of environmentally-friendly agricultural products in Korea. For the purpose, this study investigated the current states of certification system through a survey of the private certificate bodies. Based on the survey, the main goals of this study are as follows : First, the main reason of providing the certification services is the academic-industrial collaboration(21.7%) followed by the revenue seeking of the organizations (20.0%). Second, the average number of cases per private certificate bodies is 277 cases for 1,195 farms, and the average net revenue per authority is estimated as 16.84 million Won with the average total revenue of 262.09 million Won and the average total cost of 255.04 million Won. Third, in order to improve the reliability of the certificate bodies requires a variety of policy options.

Reliability Study of Three-Dimensional Motion Analysis Program for Wrist and Finger Joint Range of Motion Measurement (손목 · 손가락 관절가동범위 측정에 관한 3차원 동작분석 프로그램의 신뢰도 연구)

  • Park, Sun Ha;Park, Ji-Hyuk;Kim, Jong Bae;Jung, Young Jin;Lee, Joo Hyun;Park, Hae Yean
    • Therapeutic Science for Rehabilitation
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    • v.12 no.1
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    • pp.79-92
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    • 2023
  • Objective : This study aimed to assess the reliability of a three-dimensional (3D) motion analysis program for measuring the range of motion (ROM) of wrist and finger joints. Methods : The study recruited 50 people who had no restrictions on wrist and finger movements, understood the purpose of this study, and agreed to participate. Using a goniometer and a 3D motion analysis program, a total of 11 wrist and finger ROM were measured once each. To measure the reliability of the 3D motion analysis program, the degree of agreement and inconsistency of the measured values were compared. Results : Analysis of the degree of agreement of the measured values revealed that 38 out of 44 items showed a very high degree of agreement. Regarding analysis of inconsistency in the measured values, inconsistencies were found in three items. Conclusion : The results of this study confirmed that the ROM of the joint could be measured using the 3D motion analysis program applied in this study. In addition, it might be expected that the 3D motion analysis program would be used in various clinical fields owing to the advantages of measurement convenience and accuracy.

Application of Near-Infrared Spectroscopy in Neurological Disorders: Especially in Orthostatic Intolerance (신경계 질환에서 근적외선분광분석법의 적용: 기립불내증을 중심으로)

  • Kim, Yoo Hwan;Paik, Seung-ho;Phillips V, Zephaniah;Seok, Hung Youl;Jeon, Nam-Joon;Kim, Beop-Min;Kim, Byung-Jo
    • Journal of the Korean neurological association
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    • v.35 no.1
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    • pp.8-15
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    • 2017
  • Near-infrared spectroscopy (NIRS), a noninvasive optical method, utilizes the characteristic absorption spectra of hemoglobin in the near-infrared range to provide information on cerebral hemodynamic changes in various clinical situations. NIRS monitoring have been used mainly to detect reduced perfusion of the brain during orthostatic stress for three common forms of orthostatic intolerance (OI); orthostatic hypotension, neurally mediated syncope, and postural orthostatic tachycardia syndrome. Autonomic function testing is an important diagnostic test to assess their autonomic nervous systems for patients with symptom of OI. However, these techniques cannot measure dynamic changes in cerebral blood flow. There are many experimentations about study of NIRS to reveal the pathophysiology of patients with OI. Research using NIRS in other neurologic diseases (stroke, epilepsy and migraine) are ongoing. NIRS have been experimentally used in all stages of stroke and may complement the established diagnostic and monitoring tools. NIRS also provide pathophysiological approach during rehabilitation and secondary prevention of stroke. The hemodynamic response to seizure has long been a topic for discussion in association with the neuronal damage resulting from convulsion. One critical issue when unpredictable events are to be detected is how continuous NIRS data are analyzed. Besides, NIRS studies targeting pathophysiological aspects of migraine may contribute to a deeper understanding of mechanisms relating to aura of migraine. NIRS monitoring may play an important role to trend regional hemodynamic distribution of flow in real time and also highlights the pathophysiology and management of not only patients with OI symptoms but also those with various neurologic diseases.

Preliminary Structural Geometry Interpretation of the Pyeongchang Area in the Northwestern Taebaeksan Zone, Okcheon Belt: A Klippe Model (옥천대 북서부 태백산지역 평창 일대의 클리페 모델 기반 구조기하 형태 해석 예비 연구)

  • Heunggi Lee;Yirang Jang;Sanghoon Kwon
    • Economic and Environmental Geology
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    • v.56 no.6
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    • pp.831-846
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    • 2023
  • The Jucheon-Pyeongchang area in the northwestern Taebaeksan Zone of the Okcheon fold-thrust belt preserved several thrust faults placing the Precambrian basement granite gneisses of the Gyeonggi Massif on top of the Early Paleozoic Joseon Supergroup and the age-unknown Bangrim Group. Especially, the thrust faults in the study area show the closed-loop patterns on the map view, showing older allochthonous strata surrounded by younger autochthonous or para-autochthonous strata. These basement-involved thrusts including Klippes will provide important information on the hinterland portion of the fold-thrust belt. For defining Klippe geometry in the thrust fault terrains of the Jucheon-Pyeongchang area by older on younger relationship, the stratigraphic position of the age-unknown Bangrim Group should be determined. The Middle Cambrian maximum depositional age by the detrital zircon SHRIMP U-Pb method from this study, together with field relations and previous research results suggest that the Bangrim Group overlies the Precambrian basement rocks by nonconformity and underlies the Cambrian Yangdeok Group (Jangsan and Myobong formations). The structural geometric interpretation of the Pyeongchang area based on newly defined stratigraphy indicates that the Wungyori and Barngrim thrusts are the same folded thrust, and can be interpreted as a Klippe, having Precambrian hanging wall granite gneisses surrounded by younger Cambrian strata of the Joseon Supergroup and the Bangrim Group. Further detailed structural studies on the Jucheon-Pyeongchang area can give crucial insights into the basement-involved deformation during the structural evolution of the Okcheon Belt.

A Study on University Student's Recognition Type for Student Records: Focused on Chonnam National University (학생기록물에 대한 대학생의 인식 유형 연구 - 전남대학교를 중심으로 -)

  • Kang, Hye-Ra;Chang, Woo-Kwon
    • Journal of the Korean BIBLIA Society for library and Information Science
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    • v.28 no.3
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    • pp.95-123
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    • 2017
  • This study brings up that further studies on the perceptions of university students should be conducted for efficient management of student records. Moreover, the Q methodology is used to identify subjective recognition (Q1) type related to the importance of student records and subjective perception (Q2) of student records type. For this purpose, I carried out questionnaires and interviews with eight students by each grade at Chonnam National University. As a result, Q1 type was derived from Collective Evidence type, Independent activity type, Democratic witness type, and achievement-oriented type. The type of Q2 is derived from Historical Value of Community Type, Personal Possession Type, Historical Expert Management Type, Value for Historical Practical Use Type, and Non-historical Preservation Type. Based on the research results, the following are suggested: First, the management of student records is needed in a way that encompasses various records of various records properties. Second, the management of student records should be established from the perspective of the Community Archives. Third, a strategic measure for the preservation of student records produced by students is necessary (e.g., a campaign for conservation of student records).