• Title/Summary/Keyword: 전기체

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Induction of Spontaneous Neutrophil Apoptosis by 4-O-Methyl-Ascochlorin, A Prenyl Phenol Compound (프레닐 페놀계 항생제인 4-O-methyl-ascochlorin에 의한 호중구 세포사멸의 유도)

  • Son Dong-Aoon;Lee Sun-Young;Lee Min-Jung;Park Joo-In;Hong Young-Seob;Lee Yong-Hwan;Chang Young-Chae;Kwak Jong-Young
    • Journal of Life Science
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    • v.16 no.1
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    • pp.30-36
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    • 2006
  • Neutrophils are short-lived leukocytes that play a vital role in immune responses to bacteria, yeast, and fungi. This study was performed to investigate the effect of 4-O-methyl-ascochlorin (MAC), an anti-tumor, antibiotic, and anti-fungal prenyl-phenol compound on the spontaneous apoptosis of human neutrophils. MAC time- and dose-dependently accelerated the spontaneous apoptosis of human neutrophils. The effect of MAC on neutrophil apoptosis was blocked by pre-treatment of the neutrophils with specific inhibitors of pancaspase (zVAD-fmk), caspase-8 (zIETD-fmk), or caspase-3 (zDEVD-fmk). The cleavage of procaspase-8 and procaspase-3 was increased by MAC. Mitochondrial permeability, which was measured by the retention of $DiOC_6(3)$, was dose-de-pendently increased by MAC but the change of mitochondrial permeability was not blocked by pretreatment of neutrophils with zIETD-fmk. These results suggest that MAC induces neutrophil apoptosis by caspase-8-dependent but mitochondria-independent manner.

Composition of Buckwheat (Fagopyrum esculentum Moench) Cultivars from Korea (한국산 메밀의 성분)

  • Shim, Tae-Heum;Lee, Heok-Hwa;Lee, Sang-Young;Choi, Yong-Soon
    • Korean Journal of Food Science and Technology
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    • v.30 no.6
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    • pp.1259-1266
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    • 1998
  • To clarify the values and varieties of the buckwheats as a dietary source of nutritional and functional components, thirteen different samples of buckwheat were analyzed for this investigation. Six developed seeds were given by RDA, Korea or RDA branch of Kangwondo, and seven land race seeds were collected from a farmhouse. Amino acid analysis showed that glutamate, arginine and asparagine were major amino acids, whereas tryptophan, methionine and cysteine were minor ones of buckwheat. In addition, tryptophan content of buckwheat cultivars from Korea was 195 mg% on average. The content of rutin tended to be higher in developed cultivars than land races. On the other hand, the contents of phytic acid in buckwheats were in the range of 7.0 to 13.6 mg/g. In the tocopherol homologues of the buckwheats analyzed by HPLC, mean ${\gamma}-tocopherol$ contents were 6.16 mg/100 g with the actual range of $4.67{\sim}8.58\;mg/100g$, whereas ${\beta}-form$ was very low or zero. There were a big variations in the iron content of the buckwheats of the minerals. SDS-PAGE showed that total proteins from buckwheats exhibited a relatively similar electrophoretic patterns on the whole. The results show that CV Suwon 1 has good quality, judged from the distribution of the components of buckwheats analyzed.

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Measurement of Flexural Modulus of Lamination Layers on Flexible Substrates (유연 기판 위 적층 필름의 굽힘 탄성계수 측정)

  • Lee, Tae-Ik;Kim, Cheolgyu;Kim, Min Sung;Kim, Taek-Soo
    • Journal of the Microelectronics and Packaging Society
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    • v.23 no.3
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    • pp.63-67
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    • 2016
  • In this paper, we present an indirect method of elastic modulus measurement for various lamination layers formed on polymer-based compliant substrates. Although the elastic modulus of every component is crucial for mechanically reliable microelectronic devices, it is difficult to accurately measure the film properties because the lamination layers are hardly detached from the substrate. In order to resolve the problem, 3-point bending test is conducted with a film-substrate specimen and area transformation rule is applied to the cross-sectional area of the film region. With known substrate modulus, a modulus ratio between the film and the substrate is calculated using bending stiffness of the multilayered specimen obtained from the 3-point bending test. This method is verified using electroplated copper specimens with two types of film-substrate structure; double-sided film and single sided film. Also, common dielectric layers, prepreg (PPG) and dry film solder resist (DF SR), are measured with the double-sided specimen type. The results of copper (110.3 GPa), PPG (22.3 GPa), DF SR (5.0 GPa) were measured with high precision.

Characteristics and Implications of Lava Tubes from Geophysical Exploration in Jeju Island (지구물리 탐사에 의해 발견된 제주도 용암동굴의 특징과 의미)

  • Jeon, Yongmun;Ki, Jin Seok;Koh, Su Yeon;Kim, Lyoun;Ryu, Choon Kil
    • The Journal of Engineering Geology
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    • v.25 no.4
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    • pp.473-484
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    • 2015
  • Geophysical exploration using electric resistivity, ground penetrating radar (GPR), and impedance high-frequency (ZHF) surveys was conducted in Gujwa-eup, Jeju City, Jeju Island, an island in the Korea Strait, to confirm the existence of new caves near known caves. The exploration revealed a number of anomaly zones, presumed to be caves; 27 sites at suitable locations and depth ranges were selected for drilling and further surveys. However, contrary to predictions, most of the anomaly zones were clinker layers or paleosols intercalated with lavas. Only five boreholes intersected caves. The clinker layers and paleosols were possibly detected as anomalies owing to their different physical properties from the other rocks. Two of the five cave-finding boreholes penetrated Yongcheon Cave; a new cave was found at the other. The two boreholes that penetrated Yongcheon Cave were drilled in areas where the cave has not been previously reported, and thus helped correct an error in the cave distribution map. The cave newly discovered in this boring exploration is 180 m long, and it is connected to the upstream part of Dangcheomul Cave (110 m). The cave contains well-developed lava helictites, lava levees, and ropy structures; carbonate speleothems such as soda straws, stalagmites, columns, and curtain shawls are also well preserved. Notably, the unique shape of the carbonate speleothems is attributed to their growth in relation to the cavern water that flowed into the cave along plant roots.

Characterization of Physical Factor of Unsaturated Ground Deformation induced by Rainfall (강우를 고려한 불포화 지반변형의 영향인자 평가)

  • Kim, Man-Il;Jeon, Gyo-Cheol
    • The Journal of Engineering Geology
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    • v.18 no.2
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    • pp.127-136
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    • 2008
  • Geophysical survey for establishing a wide site for the distribution of water content, wetting front infiltration due to the rainfall, and distribution of groundwater level has been performed by using 8round penetration radar (GPR) method, electrical resistivity method, and so on. On the other hand, a narrow area survey was performed to use a permittivity method such as time domain reflectometry, frequency domain reflectometry, and amplitude domain reflectometry methods for estimating volumetric water content, soil density, and concentration of contaminant in surface and subsurface. The permittivity methods establish more corrective physical parameters than different found survey technologies mentioned above. In this study for establishment of infiltration behaviors for wetting front in the unsaturated soil caused by an artificial rainfall, soil physical parameters for volumetric water content, pore water pressure, and pore air pressure were measured by FDR measurement device and pore water pressure meter which are installed in the unsaturated weathered granite soil with different depths. Consequently, the authors were proposed to a new establishment method for analyzing the variations of volumetric water content and wetting front infiltration from the responses of infiltrating pore water in the unsaturated soil.

Application of Rare Earth Compounds for the Treatment of Phosphate and Fluoride in Wastewater (인산염 및 불소폐수 처리제로서의 희토류 화합물 적용에 관한 연구)

  • Kim, Jin-Wha;Shin, Sung-Hye;Song, Hye-Won;Kim, Dong-Su;Woo, Sang-Mo;Kwon, Young-Shik
    • Journal of Korean Society of Environmental Engineers
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    • v.22 no.6
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    • pp.1127-1137
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    • 2000
  • Applications of lanthanum ion and crude rare earth chloride to the phosphate wastewater and fluorine wastewater, respectively, as treatment agents were studied. For the investigation of phosphate removal characteristics according to the amount of lanthanum ion, initial phosphate content was decreased by about 50% when molar ratio of [$La^{3+}$]:[$PO_4{^{3-}}-P$] was 0.25 and nearly all of phosphate was removed when the molar ratio of [$La^{3+}$]:[$PO_4{^{3-}}-P$] to be doubled. The removal of phosphate by $La^{3+}$ appeared to reach equilibrium state rapidly, and it was exothermic reaction since the removed amount of phosphate was diminished somewhat when the reaction temperature was increased. The zeta potential of combined particulate compound of lanthanum ion and phosphate was located for its isoelectric point at pH 5.5 and the turbidity of treated wastewater was found to vary according to the pH in a similar manner as the absolute value of zeta potential of the combined particulate compound did. For the treatment of fluorine wastewater by crude rare earth chloride, the remaining fluorine content after treatment decreased as the dosage of crude rare earth chloride increased. Whereas, the turbidity of treated wastewater and the amount of sludge generated were shown to increase as more crude rare earth chloride was added. The remaining fluorine content and the turbidity of treated wastewater were decreased and the amount of sludge generated was observed to increase according the increase of coagulant dosage under the condition of constant input of crude rare earth chloride.

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한국발명특허협회 12년사 - 주요 20대 뉴-스로 본 12년의 장한 발자취

  • 신동식
    • 발명특허
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    • v.10 no.10 s.116
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    • pp.18-24
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    • 1985
  • 한국발명특허협회는 기업의 적극적인 참여와 관계당국의 지원을 받아 지난 73년 10월 18일 창립, 그간 발명 및 공업소유권관계 제위의 아낌없는 성원에 힘입어 금년 10월 18일로 12주년을 맞게 되었다. 창립당시 우리나라는 선진국으로 도약하기 위하여 경제개발과 수출드라이브 정책을 추구하기 위해 창조적 자주기술 개발과 선진기술을 도입, 소화흡수하는 것의 시급한 문제로 대두되었으며 더욱이 앞으로 다가올 본격적인 국제화 시대와 자유경쟁시대에 대비하여 외국과의 경쟁에서 이길 수 있는 산업기반의 구책이 절실했다. 이러한 시대적 요청에 부응하기 위하여는 공업소유권 제도의 확립을 통한 신기술 개발의 촉진 및 발명풍토조성이 선결 문제였으며 이를 해결코자 본회가 창립되었던 것이다. 이에 창립과 동시 공업소유권 제도의 수용태세를 갖추도록 하기 위하여 그 인식제고와 보급$\cdot$확산을 통한 제도 정착에 노력해 왔다. 그 결과 동제도의 불모지였던 우리나라 산업계에서도 공업소유권 제도에 눈을 뜨기 시작했으며 ${\ulcorner}$66발기회원${\lrcorner}$으로 출발하였던 본회는 이제 320회원에 이르게 되었다. 또 공업소유권 제도에 대한 인식을 바탕으로 발명$\cdot$신기술개발을 적극적으로 유도하기 위해 발명특허 정보의 보급에 힘써 왔으며 이에따라 기업 및 발명인들이 우수한 발명품들을 창안하여 기업화함으로써 국내 공급은 물론 수출까지 하는 사례도 많이 늘게 되었다. 그러나 무엇 보다도 획기적인 전환점은 지난 82년 한국특허협회를 한국발명특허협회로 확대 개편한데있다. 전경환 명예회장$\cdot$구자경 회장$\cdot$이태섭 상근부회장을 주축으로 재출범한 본회는 지난 4년동안 기술국립으로 지향하는 국가시책에 부응하는 기술혁신의 요체가 되는 공업소유권제도의 정착과 발명환경 조성을 위한 사업기본방향을 공업소유권 인식제고$\cdot$발명진흥장려$\cdot$특허관리체제확립 등 3대 목표에 두고 발명특허의식고양사업$\cdot$공업소유권관리요원양성배출사업$\cdot$발명진흥행사 및 전시사업$\cdot$발명지원사업$\cdot$발명보호계도사업$\cdot$공업소유권제도조사연구사업$\cdot$공업소유권관리자료발간 보급사업$\cdot$각종 공보발간사업$\cdot$발명특허자료(책자)판매선터운영 등 중점사업을 전개하여 이제 명실상부한 국내 유일의 공업소유권 단체로 도약해가고 있다. 발명의 날 부활에 따른 기념행사를 통한 발명유공자 및 우수특허관리기업체 포상, 전국우수발명품 전시회 개최, 발명시작품제작보조, 발명장려관 설치운영, 해외출원비용 및 해외발명전 출품지원등 발명진흥장려사업에 새로운 전기를 마련한 것이다. 한 마디로 ${\ulcorner}$0년이면 강산도 변한다${\lrcorner}$는 속언을 실감하게 한다. 창립 12주년! 이제 또다시 변해가는 시점에서 지난 12년사를 20대 뉴스를 중심으로 소개한다.

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Physical and Chemical Properties of Cover Soils of waste Landfills in Kyonggi-Do Area (경기도 지역 쓰레기 매립지 복토층 토양의 이화학성)

  • 이상모;김기대;이은주;김판기;이군택
    • Journal of Soil and Groundwater Environment
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    • v.7 no.1
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    • pp.53-62
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    • 2002
  • The physical and chemical properties of cover soils of 10 waste landfill sites in Kyonggi-Do area, where social circumstances at present forces to consider the reuse of landfill, were investigated to provide the informations of soil environment which are necessary to establish the appropriate ecological restoration plan of waste landfills. The pH and electrical conductivity of soils were higher in landfills sites than in reference sites (area around landfill sites), indicating the salt accumulation in surface soil. However, total-N and organic matter contents were lower in landfills sites than in reference sites. In landfill sites, the total-N and plant available-P contents were less than 0.15% and 20mg/kg, respectively. Exchangeable cations (K, Ca, Mg and Na) and heavy metal (Cd, Cr, Cu, Fe, Mn, Ni, Pb and Zn) contents varied between the landfill sites, but were higher in landfills sites than in reference sites. The major exchangeable cation of soil was Ca. Heavy metal contents were much lower than the critical concentration which phytotoxicity is considered to be possible and the standard for agricultural land of Korean Soil Environmental Preservation Act. Therefore, the proper soil management plan to increase the soil fertility is recommended for the ecological restoration of landfill using natural or artificial vegetation.

Effects of Additives on Soil Washing Efficiency for Mixed Surfactants (혼합 계면활성제에 적용된 각종 첨가제가 토양세척 효율에 미치는 영향)

  • Choi, Sang-Il;Jang, Min;Hwang, Kyung-Yub;Ryoo, Doo-Hyun
    • Journal of Korea Soil Environment Society
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    • v.3 no.1
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    • pp.65-74
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    • 1998
  • To enhance the washing efficiency of soil polluted by hydrophobic organic compounds, the effects of electrolytes and monomeric organic additives on micelle formation and washing efficiency of mixed surfactant solutions were investigated in this study. The surface tensions and critical micelle concentrations(CMCs) of the single and mixed surfactant solutions[$POE_5$/SDS] supplemented by NaCl were measured to investigate the effects on washing efficiency, and the composition ratios of surfactants and NaCl were optimized for the efficient soil washing system. As the mixing ratio of $POE_5$/SDS was increased to 80%, the mixed surfactant with 0.01M NaCl showed more proportional increase of washing efficiency than the mixed surfactant without any salts. The 3% solution of $POE_5$ and SDS(80%/2o%) with 0.01M NaCl showed the washing efficiency of 90%. However, the washing efficiency was not enhanced by NaCl addition to the single surfactant solution of $POE_5$. The CMC of SDS(0.049%) was higher than that of $POE_5$(0.016%), but the CMCs of mixed surfactants were decreased as the mixing ratio of $POE_5$ was increased. Alcohols having longer chain and branched carbon chain were found to be desirable for the soil washing additives.

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Growth and electrical properties of $MgTiO_3$ thin films ($MgTiO_3$산화물 박막의 성장 및 전기적 특성 연구)

  • 강신충;임왕규;안순홍;노용한;이재찬
    • Journal of the Korean Vacuum Society
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    • v.9 no.3
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    • pp.227-232
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    • 2000
  • $MgTiO_3$thin films have been grown on various substrates by pulsed laser deposition (PLD) to investigate the application for microwave dielectrics and optical devices. Epitaxial $MgTiO_3$thin films were obtained on sapphire (c-plane$A1_2O_3$$MgTiO_3$thin films deposited on $SiO_2/Si$ and platinized silicon ($Pt/Ti/SiO_2/Si$) substrates were highly oriented. $MgTiO_3$thin films grown on sapphire were transparent in the visible and had a sharp absorption edge about 290 nm. These $MgTiO_3$thin films had extremely fine feature of surface morphology, i.e., rms roughness of 0.87 nm, which was examined by AFM. We have investigated the dielectric properties of the $MgTiO_3$thin films in $MIM(Pt/MgTiO_3/Pt)$ capacitors. Dielectric constant and loss of $MgTiO_3$thin films deposited by PLD were about 24 and 1.5% at 1 MHz, respectively. These $MgTiO_3$thin films also exhibited little dielectric dispersion.

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