• Title/Summary/Keyword: 적합도 분석

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Influences of Animal Mucins on Peroxidase Activity in Solution and on the Surface of Hydroxyapatite (동물성 Mucin이 용액상태와 Hydroxyapatite표면에서 Peroxidase 활성에 미치는 영향에 관한 연구)

  • Lee, Sang-Goo;Jeon, Eun-Hyoung;Kho, Hong-Seop
    • Journal of Oral Medicine and Pain
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    • v.33 no.3
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    • pp.229-240
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    • 2008
  • Animal mucins have structural characteristics similar to human salivary mucins. Animal mucins have been regarded as suitable substances for saliva substitutes. Since animal mucin molecules in saliva substitutes and host-derived antimicrobial salivary molecules exist simultaneously in whole saliva and the pellicles of patients with dry mouth, interactions may occur between these molecules. The purpose of this study was to investigate the influence of animal mucins on peroxidase activity in solution and on the surface of hydroxyapatite(HA) surfaces. The effects of animal mucins on peroxidase activity were examined by incubating porcine gastric mucin(PGM) or bovine submaxillary mucin (BSM) with either bovine lactoperoxidase(bLPO) or saliva samples. For solid-phase assays, immobilized animal mucins or peroxidase on three different HA surfaces(HA beads, HA disc, and bovine tooth) were used. Peroxidase activity was determined with an NbsSCN assay. The obtained results were as follows: 1. PGM enhanced the enzymatic activity of bLPO in solution phase. PGM did not affect the enzymatic activity of peroxidase in saliva sample(POS). 2. BSM did not affect the enzymatic activities of both bLPO and POS in solution phase. 3. HA-adsorbed PGM increased subsequent bLPO adsorption in all three HA phases. The activity of POS was increased on both the HA beads and bovine tooth. 4. The peroxidase activities on the HA beads and disc were increased when the HA surfaces were exposed to a mixture of bLPO and PGM. 5. The binding affinity of bLPO to PGM was greater than that of bLPO to BSM. Collectively, our results suggest that animal mucins affects the enzymatic activity of peroxidase on the HA surfaces as well as in solution. Saliva substitutes containing animal mucins may affect the function of antimicrobial components in natural saliva and saliva substitutes.

THE MORPHOLOGICAL OBSERVATION OF HUMAN GINGIVAL FIBROBLASTS ATTACHMENT AND SPREADING ON THE MECHANICAL TREATED TITANIUM PLASMA SPRAYED IMPLANT SURFACE (기계적 표면 처리된 TITANIUM PLASMA SPRAYED IMPLANT에 대한 치은섬유아세포전개양상의 형태학적 관찰)

  • Whang, Yun-Hi;Lee, Jae-Mok;Suh, Jo-Young
    • Journal of Periodontal and Implant Science
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    • v.25 no.3
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    • pp.741-755
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    • 1995
  • Currently titanium is the material of choice for implants because of its biological acceptance. This high degree of biocompatibility is thought to result, in part, from the protective and stable oxide layer that presumably aids in the bonding of the extracellular matrix at the implant-tissue interface. Endosseous dental implants are interfaced with bone, connective tissue, and epithelium when implanted into the jaw bone. The soft tissue interface including connective tissue and epithelium is one of the most critical factors in the determination of implant maintenance and prognosis. For maintenance of failing or failed implants, it is essential to treat the implant fixture surface to remove bacterial endotoxins and make a surface tolerated by surrounding soft and hard tissues. In this study, the effect of mechanical treatment on titanium plasma sprayed implant on adhesiveness and proliferation of human gingival fibroblasts and changed surface characteristics were studied. titanium plasma sprayed discs manufactured by Friedrichsfeld company were treated with loaw speed stone bur, a rubber point and a jetpolisher. Its surface components were analyzed with Energy dispersive X-ray spectroscopy to evaluate whether the surface characteristics were altered or not. To observe the spreading pattern of the human gingival fibroblasts which attached to the all specimens author used the scanning electron microscope. The results were as follows : Pure titanium and plasma sprayed titanium, stone polished titanium showed titanium peak and small amout of aluminum, so there was no alteration on surface characteristics. Under the scanning electron microscopic examination in the initial attachment of human gingival fibroblast, there was a slight enhancement in pure titanium, stone polished titanium than plasma sprayed titanium. After 6 hours, the pure titanium and stone polished titanium showed human gingival fibroblasts were elongated and connected with numerous processes. Human gingival fibroblasts were more intimately attached on the pure titanium discs than on the other discs. The human gingival fibroblasts attached on the plasma sprayed titanium by thin and elongated processes. After 24 hours, the human gingival fibroblasts connected with each other via numerous processes and compeletly covered the pure titanium and stone polshed titanium discs. Human gingival fibroblasts had multiple point contacts with more long and thin lamellopodia and showed a little bare surface on plasma sprayed titanium discs.

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A Model based Vocational Evaluation for People with Psychiatric Disabilities (정신장애인 직업재활모델과 직업평가 - 직업기능척도 개발을 위한 예비연구 -)

  • Lee, Seong-Gyu;Kim, Sang-Hee
    • Korean Journal of Social Welfare
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    • v.54
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    • pp.123-147
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    • 2003
  • It is well known that one of essential features of psychiatric disability is vocational impairment. Since the year of 2000 when psychiatric disability was declared as one of disability categories in Korea, vocational rehabilitation programs have been actively administered. At this point, it is compelling that vocational evaluation serves as a means of screening out the most promising candidates, identifying their vocational deficits and strengths, designing the individualized vocational interventions, and evaluating vocational outcomes. Still, vocational evaluation for people with psychiatric disabilities has been more problematic than for any other group with disabilities. The authors argued that vocational evaluation for people with psychiatric disabilities should be based on a certain vocational rehabilitation model to address those problems. It is because there exists an indispensible relationship between the vocational rehabilitation model and vocational evaluation. In other words, the main purposes, measurement time points, and focus of vocational evaluation may depend on which of vocational rehabilitation models to make a choice of. In addition, the vocational rehab model(i.e., vocational readiness model or graduation model) underlying traditional vocational evaluation does not seem to work for people with psychiatric disabilities. Authors argued that accelerating model fits for psychiathric characteristics which are often unpredictable and turbulent. As a preliminary step of developing vocational functioning instrument incorporating the demand characteristics of the accelerating model, post-hoc analyses were done on data from a vocational functioning measure and the results were critically examined from viewpoints of accelerating model. For these purposes, discussions were made about a) general functioning of vocational evaluation, (b) relation between vocational rehabilitation model and vocational evaluation, (c) the reasons why the accelerating model is more appropriate to the characterstics of psychiatric clients than the graduation model, (d) post-hoc analytic results reviewed from viewpoints of accelerating model-based vocational evaluation This study is significant in that it attempted model-based, model-specific vocational evaluation as a preliminary step for developing vocational functioning assessment instruments ill future.

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Serum Immunoglobulin levels in Coal Worker's Pneumoconiosis Patients (진폐증 환자에서의 혈청 면역 글로불린의 변화)

  • Yoo, Kwang-Ha;Ahn, Chul-Min;Kim, Hyung-Joong;Kim, Young-Ho;Lee, Yong-Kyoo;Kim, Sung-Kyu;Lee, Won-Young
    • Tuberculosis and Respiratory Diseases
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    • v.46 no.2
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    • pp.165-174
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    • 1999
  • Background: Coal-worker's pneumoconiosis(CWP) is radiologically divided into two major groups: simple pneumoconiosis (SP), in which small, rounded or irregular opacities smaller than 1cm are observed, and progressive massive fibrosis(PMF), which is characterized by opacities larger than 1cm. SP has a life expectancy equivalent to miners with no radiographic evidence of CWP, but PMF is associated with more obvious impairments of ventilatory capacity and premature death. But only minority of workers develop PMF when exposed to dust concentrations similar to those experienced by workers who develop only SP. In this study, immune status in patients with CWP were evaluated by measurement of the serum immunoglobulin levels between control, SP and PMF groups. Method: Coal workers selected for this study were emplyees of the Tae-Baek and Dong-Hae Hospital. All the patients were men of 45-76 years old and the mean duration of exposure to coal dust were 23.2 years. By X-ray examination, 51 patients were classified in SP, 59 in PMF category. The normal controls examined were 58 men of 26-70 years old. Serum Ig levels were estimated by using Nephelometer(Behring Nephelometer : Germany) and serum were collected 51 in SP, 49 in PMF and 57 cases in control group. Results: The levels of IgG were increased but the levels of IgM were decreased with increasing age in control groups. There were no statistical difference of immunoglobulin levels between smokers and nonsmokers in control groups. There were no statistical difference of immunoglobulin levels between Control, SP and PMF groups. Multiple regression analysis were undertaken to determine the statistical significance of the apparent trends and estimate the effects associated with age, smoking habit and radiological category of CWP. According to this analysis, the levels of IgG were decreased significantly in SP group and had decreasing tendancy, but not statistically significant in PMF group. Conclusion : From the observations described, CWP patients had decreased IgG concentration compared to control gorup. Therefore, there was some relation between CWP and immunoglobulin concentration.

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Strategy Development for Expanding High-speed Railway into both Korean Domestic Market and Foreign Market (고속철도사업 활성화 및 건설업체의 해외사업참여 확대방향 연구)

  • Park, Heedae;Park, Hyung Keun;Jang, Hyeon Seok;Han, Seung Heon
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.31 no.1D
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    • pp.119-126
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    • 2011
  • High-speed railway raises global interests with the growing concerns on the green development and the green energy. However, since most of the infrastructure investment of Korea was focused on the highway projects for last forty years, the investment on the railway has been limited around 40~50% of that of the highway projects. In addition, due to the world economy crisis and unsatisfactory support of existing policy for the private investment project, the private investment is given a small deal of weight on the social overhead capital investment. Meanwhile, despite the world high-speed railway market is growing rapidly and the Korean contractors have won the international construction contracts over 70 billion USD, past records of railway projects are very rare. Therefore, it is required to develop strategies for encouraging private investment in the domestic market to achieve efficient high-speed railway development and for advancing into foreign high-speed railway market. This study carried out data collection and market analysis for both domestic and foreign market respectively. Through a structured questionnaire survey and expert interviews, contractors' perceptions on the high-speed railway market and needs for the government support are collected. Summary of strategies drawn from this study are as follows: 1) carrying out BTL high-speed railway projects and revising related policies; 2) upwarding incentive level for the private pre-investment projects considering the contractors' credit rating; 3) carrying out Honam-Jeju submarine railway project; 4) establishing a efficient consortium model for foreign market; 5) improving the capacity of the Korea Railway Association that support Korean contractors' foreign advancement; and 6) expand the budget for Global Infra-fund.

A STUDY ON THE STRUCTURAL RELATIONSHIP AMONG TEST ANXIETY, PSYCHOPATHOLOGY, TEMPERAMENT & FAMILY ENVIRONMENT (시험불안과 정신병리, 기질 그리고 가정환경 간의 구조적 관계에 관한 연구 - 시험불안-우울-불안-자기개념-가정환경간의 인과적 관계분석 -)

  • Cho, Soo-Churl;Yoo, Tae-Ik;Shin, Min-Sup
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.10 no.1
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    • pp.50-63
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    • 1999
  • Introduction:Test anxiety is a pervasive problem among high school students in Korea. While anxiety in test situations may actually facilitate the performance of some students, more often it is disruptive and leads to performance decrements. Over the past years, many child psychiatrists have become concerned with understanding the nature of test anxiety, but it is not clearly understood yet. In order to understand the nature of test anxiety, the relationship between test anxiety and depression, state anxiety, trait anxiety, temperament and family environment were examined. Methods:The Test Anxiety Inventory, Chidlren's Depression Inventory, State-Trait Anxiety Inventory, Temperamnet and Family Environment Scale Scale were administered to 576 high school students in Seoul. The relationships between test anxiety and other measures were tested using Pearson correlation coefficients and to test the causal relationship among the variables, regression analysis was performed. Results:The correlation coefficients between test anxiety and depression, state anxiety, trait anxiety, temperament and family environment scale were 0.42(p<0.01), 0.34(p<0.05), 0.38(p<0.05), 0.36(p<0.05) and -0.23(p<0.01), respectively. Regression analysis showed that only state and trait anxiety had direct causal relationship with test anxiety. Depression, temperament and family environment were indirecly related with test anxiety. Conclusions:This study indicates that the level of state and trait anxiety are directly related with test anxiety, and other variables such as temperament, family environment and depression are indirectly related with test anxiety. Thus, in order to develop the effective methods for treatment, these psychopathological characteristics should be kept in mind and the most important factors are the levels of state and trait anxiety.

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Development of Solar Warehouse for Drying and Storing the Agricultural Products (농산물(農産物) 건조(乾燥) 및 저장(貯藏)을 위(爲)한 태양열(太陽熱) 저장고(貯藏庫)의 개발(開發)에 관(關)한 연구(硏究))

  • Kim, Man Soo;Chang, Kyu Seob;Kim, Soung Rai;Jeon, Byeong Seon
    • Korean Journal of Agricultural Science
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    • v.9 no.1
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    • pp.357-370
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    • 1982
  • Recent concern regarding price and availability of fossil fuels has spurred the interest in alternative sources for farm crop drying. Among the available options such as biomass energy, wind power, nuclear energy and solar energy etc., the increasing attention is being directed to the utilization of heat from solar energy especially for farm crop drying. Even though solar energy is dispersed over a large land area and only a relatively small amount of energy can be simply collected, the advantages of solar energy is that the energy is free, non-polluting. The study reported here was designed to help supply the informations for the development of simple and relatively inexpensive solar warehouse for farm crop drying and storage. Specifically, the objectives of this study were to determine the performance of the solar collector fabricated, to compare solar supplemented heat drying with natural air drying and to develop a simulation model of temperature in stored grain, which can be used to study the effects due to changes in ambient air temperature. For those above objectives, solar collector was fabricated from available materials. Corrugated steel galvanized sheet, painted flat black, was used as absorbers and clear 0.2mm polyethylene sheet was the cover material. The warehouse for rough rice drying and storage was constructed with concrete block, and the solar collector was used as the roof of warehouse instead of original roofing system of it. The results obtained in this study were as follows: 1. The thermal efficiency of the solar collector was average 26 percent and the overall heat transfer coefficient of the collector was approximately $25kJ/hr.m^2\;^{\circ}K$. 2. Solar heated air was sufficient to dry one cubic meter of rough rice from 23.5 to 15.0 percent in 7 days and natural air was able to dry the same amount of rough rice from 20.0 to 5 percent in l2 days. 3. Drying with solar heat reduced the required drying time to dry the same amount of rough rice into a half compared to natural air drying, but overdrying problems of the bottom layer were so severe that these problems should be thoroughly analyzed. 4. Simulation model of temperature in stored grain was developed and the results of predicted temperature agreed well with test results. 5. Based on those simulated temperature, changes in the grain-temperature were a large at the points of the wallside and the damage of the grain would be severe at the contact area of wall.

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Restoration for Evergreen Broad-leaved Forests by Successional Trends of Pasture-grassland in the Seonheulgot, Jeju-do (제주도 선흘곶 초지지역의 천이경향을 고려한 상록활엽수림 복원 연구)

  • Han Bong-Ho;Kim Jeong-Ho;Bae Jeong-Hee
    • Korean Journal of Environment and Ecology
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    • v.18 no.4
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    • pp.369-381
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    • 2004
  • This study was achieved to present the way to restore the Seonheulgot pasture-grassland damaged by landuse and interference for a long time to evergreen broad-leaved forests as the native vegetation structure. As a result of analyzing ecological succession tendency of structure in survey area, we established the optimal restoration model. The total of survey sites were 26, and the classified plant community types were four types by M.I.P of dominant woody species. Finally we classified the four types based on diameter of dominant woody species in canopy layer. The six community types are as follows: Community I was runner-shrub forest, community II was evergreen broad-leaved shrub forest, and community III was evergreen broad-leaved forest of small diameter. Community IV and V were evergreen broad-leaved forest of middle diameter. Community Ⅵ was evergreen broad-leaved forest of large diameter. The number of constituent species was 24 in community I, 28 in community II as the shrub forest, 16 as the evergreen broad-leaved forest of small diameter, 29 in community III, 30 in community IV as the evergreen broad-leaved forest of middle diameter and 27 in community Ⅵ as the evergreen broad-leaved forest of large diameter. The range of Shannon's index of all communitys was from 0.8763 to 1.2630 and the Similarity index between the community composed of middle diameter woody species and large diameter woody species. The ecological succession of community I, II, and III were changed from pasture-grassland to broad-leaved forest and the structure of community IV, V, and Ⅵ was similar to evergreen broad-leaved forest in warm temperate region. We suggest the restoration planting model evergreen broad-leaved forest of in Seonheulgot pasture-grassland, as follows: The target restoration vegetation were Castanopsis cuspidata var. sievoldii community and Queycus glauca community. Castanopsis cuspidata var. sievoldii and Quercus glauca should be dominant woody species in canopy layer, the number of trees was 10 per 100$m^2$, and Castanopsis cuspidata var, sievoldii, Quercus glauca, Camellia japonica, and Eurya japonica should be dominant woody species in the understory layer, the number of trees was 14 per 100$m^2$.

Shoot Growth and Fruit Characteristics According to Bearing Branch Direction and Thickness in 'Kawanakajima Hakuto' Peach Trees (복숭아 '천중도백도'의 결과지 방향 및 굵기에 따른 신초 생장과 과실 특성)

  • Yun, Seok Kyu;Yoon, Ik Koo;Nam, Eun Young;Jun, Ji Hae;Kwon, Jung Hyun;Bae, Haejin;Kim, Ho Cheol;Kim, Tae-Choon
    • Horticultural Science & Technology
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    • v.32 no.4
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    • pp.421-426
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    • 2014
  • To investigate the optimal size of fruit bearing branches (FBBs) of 'Kawanakajima Hakuto' peach (Prunus persica Batsch) for production of high quality fruits, we evaluated shoot growth and fruit characteristics relative to FBB direction and thickness. FBB diameter, shoot length, fruit weight, and soluble solids content (SSC) averaged 6.9 mm, 32.6 cm, 333.6 g, and $11.2^{\circ}Brix$, respectively. Coefficients of variation of FBB diameter and shoot length were high as 35.8% and 75.3%. The highest frequency values revealed that 76.4% of FBBs had a diameter below 9.0 mm, 70.0% of shoot lengths were less than 40 cm, 24.8% of fruits were 310-340 g, and 66.9% of SSCs were $10.5-12.5^{\circ}Brix$. Shoot length and SSC were significantly affected by FBB diameter without direction, and fruit weight was significantly affected by interaction of FBB diameter and direction. There was a negative correlation ($r^2=0.094^*$) of FBB diameter and fruit weight with upward FBB directions, whereas FBB diameter and fruit weight were positively correlated ($r^2=0.246^{**}$) with downward FBB direction. With thick FBB diameter, shoot length, and SSC were significantly increased, but fruit weight was decreased. Therefore, downward FBBs below 9.0 mm in thickness are suitable for producing high-quality fruits of 'Kawanakajima Hakuto' peach.

Influence of Climate Factors and PM10 on Rotaviral Infection: A Seasonal Variation Study (Rotavirus 감염의 연도별 유행시기의 변동양상 및 기후요소와 PM10과의 관계)

  • Im, Hae-Ra;Jeon, In-Sang;Tchah, Hann;Im, Jeong-Soo;Ryoo, Eell;Sun, Yong-Han;Cho, Kang-Ho;Im, Ho-Joon;Lee, Gwang-Hoon;Lee, Hak-Soo;Kang, Yune-Jeung;Noh, Yi-Gn
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.6 no.2
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    • pp.120-128
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    • 2003
  • Purpose: Recently, while the authors were experiencing that the epidemic period of rotaviral infection happened more in the early spring, we tried to find out how the outbreaks of rotaviral infection are changing in detail depending on the weather condition since it has something to do with the climate factors and PM10. Methods: Fourteen hundreds seventy nine patients who were proved to be positive to rotavirus were chosen among children less than 5 years old from January 1995 to June 2003. Among various climate factors, monthly average temperature, humidity, rainfall and PM10 were selected. Results: Rotaviral infection was most active in 2002 as 309 (20.9%) patients. It has been the spring that is the most active period of rotaviral infection since 2000. The temperature (RR=0.9423, CI=0.933424~0.951163), rainfall (RR=1.0024, CI=1.001523~1.003228) and PM10 (RR=1.0123, CI=1.009385~1.015248) were significantly associated with the monthly distribution of rotaviral infection. Conclusion: Through this study we determined that the epidemic period of rotaviral infection is changed to spring, which is different from the usual seasonal periods such as late fall or winter as reported in previous articles. As increased PM10 which could give serious influence to the human body, and changing pattern of climate factors such as monthly average temperature and rainfall have something to do with the rotaviral infection, we suppose that further study concerning this result is required in the aspects of epidemiology, biology and atmospheric science.

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