• KIISE Transactions on Computing Practices
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• v.23 no.6
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• pp.371-378
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• 2017

In modern society, awareness of diabetes is growing with an increase in the elderly population and an increase in the incidence of diabetes. In particular, diabetic patients can suddenly develop hypoglycemic shock; therefore, it is important to measure blood glucose periodically. However, self-monitoring blood glucose meters are difficult to carry and it is difficult to manage the value. To solve these problems, the blood glucose measurement system has been developed as a sensor attached to the body or as one of the functions of smart devices, but it has not been commercialized. In this paper, we propose a smart band with a blood glucose measurement function. If a user enters a schedule to measure blood glucose level, such as before/after meals, in the app, he/she can receive a measurement alarm from the band. The user can measure the blood glucose level at any time using the band, and the measured value is transmitted and managed by the app including behavior history such as before/after meals and the time. This will help the user to manage, diagnose and prevent health problems. The system has been tested using two medical device-certified products, and each blood glucose measurement value has been confirmed to be more accurate.

• Monthly Korean Chicken
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• v.15 no.12
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• pp.113-117
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• 2009

• The Monthly Diabetes
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• s.256
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• pp.52-53
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• 2011

• The Monthly Diabetes
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• s.221
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• pp.36-39
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• 2008

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2003.05c
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• pp.28-32
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• 2003

본 논문은 시료의 양을 최소화하고 혈중 요소 및 혈당 농도에 대한 정확한 측정을 위하여 최근에 개발된 전기화학형 마이크로 전극형 센서의 간략한 소개 및 전기적인 특성에 관하여 요약하는 것에서 출발하여 센서로부터 전기신호를 발생시키는 signal conditioning 회로의 설계, microprocessor를 이용한 digital 값으로의 변환 및 data 취득, 취득한 data를 측정된 혈당량 및 요소량으로의 변환 저장 display까지의 휴대용 계측기의 prototype 개발에 관하여 기술한다. 이 계측기는 미량의 혈액채취 한번으로 농도를 측정하는 측정모드와, 측정된 data를 찾아보기 위한 검색모드로 작동시킬 수 있다. Microprocessor의 기능을 최대한 사용하여 측정기의 크기를 소형화하였으며 LCD(Liquid crystal display)틀 채택하는 등 저전력 회로로 구현하였다.

• Journal of the Korean Data and Information Science Society
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• v.22 no.3
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• pp.413-421
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• 2011

The present study was carried out to summarize the effect of garlic in the hyperlipidemia rats by meta-analysis related studies. The association measure to test effect of garlic was the mean difference (MD). In this particular fixed-effect model of mean difference, body weight, liver weight, kidney weight and heart weight were significantly decreased (p < 0.05). Also, blood glucose, plasma total cholesterol, plasma triglycerides, LDL-cholesterol, liver cholesterol, liver triglycerides were significantly decreased. HDL-cholesterol was significantly increased. In this case of heterogeneous variable, random effect model was applied. In this model, liver weight, blood glucose, plasma total cholesterol, plasma triglycerides, LDL-cholesterol, liver cholesterol, liver triglycerides were significantly decreased. HDL-cholesterol was significantly increased. According to the meta-regression analysis, duration of injection was significantly for kidney weight, testis weight, plasma total cholesterol, plasma triglycerides, HDL-cholesterol, LDLcholesterol, liver cholesterol, liver triglycerides.

• Journal of The Korean Society of Inherited Metabolic disease
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• v.17 no.2
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• pp.69-76
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• 2017

Citrin deficiency is an autosomal recessive disorder caused by mutations in the SLC25A13 gene on chromosome 7q21.3, and a type of urea cycle disorder that causes hyperammonemia. Although neonatal intrahepatic cholestasis and adult-onset type II citrullinemia, a type of citrin deficiency, have been described well in many articles for several decades, failure to thrive and dyslipidemia caused by citrin deficiency (FTTDCD), the other type of citrin deficiency, has been only identified recently. There was previously no case report about FTTDCD in Korea. Patients with FTTDCD could present with loss of appetite, fatigue, failure to thrive, hypoglycemia, hypercitrullinemia, dyslipidemia, and an increased lactate/pyruvate ratio. Routine evaluation may not reveal the cause of hypoglycemia caused by citrin deficiency. We recently had a case that presented with recurrent hypoglycemia in a 30-month-old boy. Chemistry profiling, urine organic acid analysis, plasma acylcarnitine analysis, and hormone studies indicated values within the normal range or non-specific findings. Mutation analysis to identify the cause of hypoglycemia identified the subject as a compound heterozygote carrying each of the c.852_855del ($p.Met285Profs^*2$), and c.1177+1G>A mutant alleles. We report here on this unusual case of citrin deficiency presenting with FTTDCD for the first time in Korea.

• The Monthly Diabetes
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• s.287
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• pp.44-45
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• 2013

당뇨병은 흔히 비만한 사람에게서 많이 발생된다고 생각한다. 하지만 간혹 채식 위주의 편식 등의 잘못된 식습관과 과도한 스트레스로 영향 결핍형 저체중이 와서 혈당조절이 안 되는 경우가 종종 있다. 이때에는 체중감량을 위한 일반적인 식사요법과는 다른 방법이 필요하다.

• Journal of Nutrition and Health
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• v.43 no.4
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• pp.333-341
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• 2010

The aim of this study was to investigate the hypolgycemic activity of water extract of fermented yacon (Smallanthus sonchifolius) leaves tea (Yacon LWE) in high-fat diet (HFD)/streptozotocin (STZ)-induced diabetic mice. Male ICR mice were fed with a HFD (37% calories from fat) for 4 weeks prior to intraperitoneal injection with STZ (100 mg/kg body weight). Diabetic mice were supplemented with two doses of Yacon LWE (0.16% and 0.8%, wt/wt) for 6 weeks. The supplementation of high-dose Yacon LWE significantly lowered blood glucose levels and plasma ALT and AST activities compared with the control group. High-dose Yacon LWE also improved the insulin tolerance without any changes in plasma and pancreatic insulin concentrations in HFD/STZ-induced diabetic mice. Yacon LWE supplementation increased the insulin staining of pancreatic $\beta$-cells in a dose-dependent manner. Both 0.16% and 0.8% of Yacon LWE significantly elevated plasma leptin concentration, hepatic glucokinase activity and glucokinase/glucose-6-phosphatase ratio compared with the control group. However, glycosylated hemoglobin concentration was not different among the groups. These results suggest that high-dose Yacon LWE lowers the blood glucose level partly by enhancing insulin sensitivity and hepatic glucose metabolism in type 2 diabetic mice.

• Child Health Nursing Research
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• v.26 no.2
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• pp.212-221
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• 2020

Purpose: Nursing protocols for glucose management are well known for both healthy term newborns and high-risk newborns. However, for less risky newborns who are under only observation surveillance, hypoglycemia could be overlooked unless clinical symptoms develop. Methods: A retrospective study was performed to explore factors influencing variations in glucose levels in 91 newborns who did not require any interventions, but were under nursing surveillance, at a level II neonatal intensive care unit. Data were retrieved from electrical medical records on glucose levels, demographic characteristics, and other clinical characteristics of newborns in their first day of life from January 2016 to May 2019. Results: Glucose levels tended to stabilize within the normal range (60~80 mg/dL) as time passed during the first day of life. Cesarean section, multiple gestation, abnormal growth, and later preterm birth were associated with low glucose levels in the first 2 hours of life. Thirty-one newborns experienced a hypoglycemic episode (< 45 mg/dL) during the first 24 hours of life. Conclusion: The findings of this study support the active encouragement of early feeding within 2 hours of birth and urgent adoption of a structural protocol for glucose surveillance in newborns with potential health problems immediately after birth.