• Korean Journal of Microbiology
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• v.55 no.1
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• pp.69-73
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• 2019

During screening of microbes for compounds having cosmetic benefits, we isolated Marinobacter salarius HL2708#2 from lava seawater on Jeju Island, Republic of Korea. The complete genome sequence was determined. Strain HL27080#2 features a circular chromosome of 4,304,603 bp with 57.21% G+C content and a 244,163 bp plasmid with 53.14% G+C. There were 4,180 protein coding sequences identified, along with 49 transfer RNA and 18 ribosomal RNA noncoding genes. The genome harbored genes for the utilization of alcohol, maltose/starch, and monosaccharide as sole carbon sources. Genes responsible for halophilic characteristics and heavy metal resistance could be annotated, as well as aromatic and alkane hydrocarbons. Contrary to the prior report that M. salarius is negative for nitrate and nitrite reduction, nitrate/nitrite reductase along with nitrate/nitrate transporters and nitronate monooxygenase were evident, suggesting that strain HL2708#2 may be able to denitrify extracellular nitroalkenes to ammonia.

• Journal of Life Science
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• v.25 no.10
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• pp.1081-1090
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• 2015

Diabetes has been one of major health risks in industrialized countries. Allium hookeri is a wild herb distributed in India and Myanmar. The root of the plant has been used as food and medicine in Southeast Asia. We investigated Allium hookeri extract improves type 2 diabetes mellitus in C57BL/KSJ db/db obese mouse. C57BL/KSJ db/db obese mouse arise out of Type 2 diabetes and we treated Allium hookeri methanol extract 400 mg/kg (AH 400), 800 mg/kg (AH 800), positive control group (thiazolidinedine;TZDs) were administered orally for 8weeks. AH treated group normalized lipid enzyme system (triglyceride, total cholesterol, HDL-cholesterol and LDL-cholesterol) and serum glucose, HbA1c and plasma insulin level. AH treated group recovered β-cell damage by hyperglycemia and fatty liver disease. AH treated group significantly up regulated expression of Peroxisome proliferator-activated receptor gamma (PPAR-γ), pyruvate dehydrogenase kinase4 (PDK4), Sterol regulatory element-binding protein 1c (SREBP 1) and fork head box O1 (FOX 01) proteins in C57BL/KSJ db/db obese mouse liver. And we found that AH treated group decreased hepatic malondialdehyde formation in C57BL/KSJ db/db obese mouse liver. These results indicate that Allium hookeri methanol extract might be a potential anti-diabetic agent and could be useful in the treatment of type 2 diabetes mellitus.

• Applied Biological Chemistry
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• v.47 no.2
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• pp.164-169
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• 2004

In the course of our screening for biocontrol agent (BCA) against Streptomyces scabiei and S. turgidiscabies causing potato scab using 5,000 actinomtcete isolates, 9 antagonistic strains were selected as BCA candidates through in vitro and in vivo assay. An antagonistic strain, A020645 was highly resistant to some pesticides and antibiotics such as dazomet and mancozeb and showed high control value in vivo. Two bioactive compounds (compound A, B) were purified by anion exchange chromatography, solid phase (ODS) extraction, TLC and reverse phase HPLC. Their chemical structures are now thought to be nucleoside derivative as determined by $^1H-NMR$ data analysis. Their full chemical structures would be elucidated through $^{13}C-NMR$, HMQC and HMBC analyses. Further studies will be focused on fitness in soil and formulation of the BCA candidates.

• The Journal of the Korea Contents Association
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• v.19 no.5
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• pp.24-34
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• 2019

This study compares in depth the song performed by two groups, one by 'Seo Taiji And His Boys'(X Generation) and the other by 'BTS'(C Generation) based on the discourse about the 'X Generation' in the 1990s and the 'C Generation' in the 2010s. It will specifically focus on the nature of 'home' that has great significance in the music video and will find the sociocultural meaning of it. Based on the analysis, the original performance by 'Seo Taiji and The Boys' demonstrated the vertical structure of enlightenment and discipline and narrated the story with the plot of 'maturity'. The meaning of 'home' in the original version shifts from a target of resistance to a subject of internalization. The remake music video of BTS demonstrated a horizontal structure of empathy and solidarity and narrated the story with the plot of 'pursuit/discovery'. The 'home' here can be considered the life itself of a person who maintains one's self identity.

• Geophysics and Geophysical Exploration
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• v.24 no.4
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• pp.164-170
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• 2021

Frequency-domain and time-domain induced polarization methods can provide spectral information about subsurface media. Analysis of spectral characteristics has been studied mainly in the frequency-domain, however, time-domain induced polarization research has recently become popular. In this study, assuming a homogeneous half-space model, an inversion method was developed to extract Cole-Cole parameters from the measured secondary potential or electrical resistivity. Since the Cole-Cole parameters of chargeability, time constant, and frequency index are not independent of each other, various problems, such as slow convergence rate, initial model problem, local minimum problem, and divergence, frequently occur when conventional nonlinear inversion is applied. In this study, we developed an effective inversion method using the initial model close to the true model by introducing a grid search method. Finally, the validity of the developed inversion method was verified using inversion experiments.

• Microbiology and Biotechnology Letters
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• v.35 no.1
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• pp.30-35
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• 2007

This study was carried out to investigate the usefulness of the aerial part of Cnidium officinale Makino as a bioactive material source. The aerial part(leaf and stem) of Cnidium officinale Makino was extracted with three kinds of solvents and determined their antimicrobial activities against several bacteria and yeast strains using the paper disc method and the microtiter dilution method. The extracts of the Cnidium offocinale aerial part exhibited the broad spectrum of antibacterial activity against Gram (+) and Gram (-) bacteria, including food-borne pathogens such as Listeria monocytogenes, Salmonella typhimurium, and Staphylococcus aureus. The extracts of Cnidium officinale also showed antifungal activity against Saccharomyces cerevisiae. The ethyl acetate extracts completely inhibited the growth of Staphylococcus aureus and Pseudomonas aerogenes, and moderately inhibited the growth of Escherichia coli and Enterobacter cloacae at the concentration of 0.5 mg/mL. However, water extract of Cnidium officinale exhibited lower antimicrobial activity than ethyl acetate and methanol extracts. The inhibitory effect of the ethyl acetate extract of Cnidium officinale Makino was not destroyed by heating at $100^{\circ}C$ for 30 min or at $121^{\circ}C$... for 15 min. These results suggest that the aerial part of Cnidium officinale Makino could be a useful source for a natural antimicrobial material.

• Korean Journal of Weed Science
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• v.13 no.2
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• pp.89-95
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• 1993

The Inhibiting activity of newly synthesized phenol (E-series) and triazine (T-series) derivatives was evaluated by using thylakoid membranes extracted from cyanobacteria (Anacystis nidulans $R_2$). There were no significant differences between phenol derivatives and dinoseb to the thylakoid membrane extracted from wild type in the Hill reaction. However, a phenol derivative, E-24 which has no -Cl at phenyl ring, did not show any activity. The longer the length of R substituents was in phenol derivatives, the lower inhibiting activity was in the Hill reaction. Triazine derivatives, T-27, T-28, T-40, T-41, T-47 and T-48 were also compared with diuron and atrazine. Among triazine compounds, T-27 and T-28 showed 10 and 30 times activity as high as atrazine to wild type, respectively. Other triazine derivatives, T-40, T-41, T-47 and T-48 showed low inhibiting activity to wild and mutant type. A structural difference of T-27 and T-28 from T-40, T-41, T-47 and T-48 was the presented of -C-NH-. Both T-27 and T-28 were very closely associated with serine, an amino acid located at the 264th position of D1 protein because of the resistant ratio(R/S) to mutant G-264 were higher than that of atrazine.

• Journal of Science and Technology Studies
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• v.5 no.2 s.10
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• pp.97-127
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• 2005

While science museums, whose functions consist traditionally in collecting, preserving, researching, and displaying science-related objects, present scientific knowledge, figures, or tools in the historical context, science centers give more emphases on science education by exposing interactive exhibits to their visitors. However, neither objects-oriented exhibits nor hands-on technologies can provide museum visitors with the full insight into modem science in terms of its complicated relationships to politics, economy, culture, art, risk, and environment. This paper argues that for the 21st century we need to establish a new kind of science museum through the critical examination of its previous kinds - science museums and science centers. In the first part of this paper, the history of the first and second generations of science museums, including their recent trends in science centers, in the West will be elaborated. Secondly, the development of national science museums in Korea will be discussed specifically for the understanding of Korean science museums. The next part of this paper will seek for the possibilities of the third generation of science museums through three examples, which show interdisciplinary, contextual, and institutional approaches to change science museums or science centers. Fourthly, the social function of science museums as 'forum' will be discussed in relation to promoting public 'participation' of science as well as public 'understanding' of science. As a conclusion, some practical suggestions and conceptual guidelines will be proposed for the future Korean national science museum.

• Korean Journal of Social Welfare Studies
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• v.45 no.3
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• pp.35-69
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• 2014

This study was conducted to explore initial motherhood experience of non-married mothers who decided to raise their babies. We applied Rennie's hermeneutic grounded theory for this study in which 7 non-married mothers participated. 9 hermeneutic categories which are 'decision to give birth', 'feeling of hitting bottom', 'ambivalence toward a life in stomach', 'realization of motherhood', 'motherhood anxiety', 'the bridle of social tag', 'hope of motherhood', 'encounter with new self' and 'visage of weary life' were constructed based on 145 meaning units, 34 subordinate categories. The core category that integrates motherhood experiences of participants was postulated as living with two conflicting visages of motherhood which are a cure and a poison at the same time. Motherhood experience processes were emerged in five stages which are decision to give birth, psychological frustration, realization of motherhood, confusion, and hope and discouragement of motherhood. Three types of motherhood experience were analyzed in the study which are adaptative, conflictive, and resistant. Based on the result of the study, the motherhood experience of non-married mother who decided to raise their babies are the process of emergence of new identity called mother. The non-married mothers formed their motherhood identities as they internalize socioculturally granted motherhood ideology. Moreover, the gap between socially oriented motherhood and realistic role of motherhood led to confusion. Based on this study, we suggest intervention plans to the field of social welfare practice that will support initial motherhood of non-married mothers who decided to keep their babies.

• Korean Journal of Culture and Social Issue
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• v.26 no.4
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• pp.351-378
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• 2020

The purpose of the study was to identify the latent classes of meta-awareness of gender discrimination among Korean young adults using Latent Profile Analysis based on 'perceived ambivalence toward men among women', 'perceived ambivalent sexism among men', 'perceived gender(reverse-) discrimination in Korea'. After identifying the latent classes, the difference between gender role conflict, sense of distance from the opposite sex, and support for gender discrimination issues were explored among the classified groups. As a result, 3 latent classes among women and 2 latent classes among men were identified. Latent classes among women were named 'women with low sensitivity of sexism', 'women with high sensitivity of sexism' and 'women against sexism' and latent classes among men were named 'men with perception of gender equality', 'men with perception of reverse discrimination'. Types with higher levels of meta-awareness of gender discrimination were related with higher gender role conflict and higher sense of distance from the opposite sex. Among women, types with higher levels of meta-awareness of gender discrimination perceived higher levels of gender discrimination and showed more support for gender discrimination issues while among men, types with higher levels of meta-perception of gender discrimination only perceived higher levels of reverse discrimination. Based on the present findings, implications about the severe gender conflict among Korean young adults are further discussed in the article.