• Title/Summary/Keyword: 재활의학부

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The Role of Glial Cells in Regenerative Responses of the Injured Corticospinal Tract Axons in Rats Treated with Cindii Rhizoma (흰쥐의 척수손상 후 천궁처리에 의한 피질척수로 축삭재생 반응시 Glial cells의 역할)

  • Han, Yeong-Su;Oh, Min-Seok
    • Journal of Korean Medicine Rehabilitation
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    • v.18 no.3
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    • pp.19-39
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    • 2008
  • Objectives : It has been reported that CG was effective in decreasing injury to neural tissues. To investigate neural responses in the injured spinal cord, an extract of CG was examined to determine its effect on neural responses in the injured spinal cords of rats. Methods : After CG treatment was applied to the spinal cord of rats given a contusion injury, the re-growth responses of injured neural tissues and corticospinal tract axons was observed by measuring the number of GAP-43, Cdc2, and phospho-Erk1/2 proteins, CST axons, GFAP-stained astrocytes, and Glial scarring in the injured spinal cord. Results : Levels of GAP-43, Cdc2, and phospho-Erk1/2 proteins were found to have increased in the injured spinal cord region. The number of GFAP-stained astrocytes also increased within and around the injury cavity. Glial scarring, which was identified by CSPG immunofluorescence staining, was reduced by CG treatment. Anterograde tracing by Dil dye showed that the elongation of the CST axons in the dorso-medial white matter area was almost completely prevented at the injury site. Collateral sprouting was observed in the spinal cord rostrally close to the injury site, and CG treatment further increased axonal arborization in the corresponding region. In vivo migration of CST axons and astrocytes using an implanted polymer tube system showed more of an increase in enhanced migration of axons and astrocytes in CG-treated group compared to the injury control group. Conclusions : These results suggest that CG activated neural responses - including astrocyte migration - and promotes axonal regenerative activity in the injured spinal cord area.

Sharing Experiences in Selecting Clinical Outcome and Approving Validated Questionnaires : Insights from an Elderly Registry Study (노인등록연구 사례를 통한 임상평가지표 선정 과정 및 검증된 설문도구 승인 경험의 공유)

  • Nahyun Cho;Hyungsun Jun;Won-Bae Ha;Junghan Lee;Mi Mi Ko;Young-Eun Kim;Jeeyoun Jung;Jungtae Leem
    • The Journal of Korean Medicine
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    • v.45 no.1
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    • pp.17-43
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    • 2024
  • Objectives: Underpinned by the context of a Korean traditional medicine cohort study on healthy aging, this research primarily aims to guide the selection of Clinical Outcome Assessments (COAs) for elderly healthy aging patient registry research, offering insights into the selection process; and secondly, to streamline the resource-intensive process of obtaining permissions for validated COAs, benefiting future traditional Korean medicine clinical researchers. Methods : In this study, we identified outcomes through a review of previous studies, followed by a process involving expert consultations to select the final outcomes. Subsequently, for the selected outcomes that were Clinical Outcome Assessments (COAs) developed tools, we searched in commercial databases to confirm the availability of Korean versions and the necessity of obtaining permissions. Finally, we obtained permissions for their utilization and, when needed, acquired the original instrument questionnaire through payment. Results: Through a literature review of existing observational studies, a total of 57 outcomes were selected, with 19 of them identified as COA instruments. Upon verifying usage permissions for these 19 instruments, it was found that 17 required author-specific permissions, and among these, 2 needed a purchase as they were commercially available. Conclusion: This study provides a detailed overview of outcome selection and permission acquisition for elderly patient registry research. It underscores the importance of Clinical Outcome Assessment (COA) tools and the rigorous approval process, aiming to enhance research reliability. Continuous verification of COA information is essential, and future research should explore Core Outcome Set (COS) development through consensus-building approaches like Delphi studies.

Effects of Irradiation on the Muscle Activity Around an Amputation Site During Proprioceptive Neuromuscular Facilitation Pattern Exercise for Upper Extremity and Scapular Exercise on the Non-Amputated Part -A Case Study- (비 절단부에 적용한 PNF 상지 패턴과 견갑골 움직임에 의한 방산이 절단부 주변 근육 활성도에 미치는 영향 -단일 사례연구-)

  • Choi, Su-Hong;Rhee, Min-Hyung;Ha, Kyung-Jin;Lee, Sang-Yeol
    • PNF and Movement
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    • v.17 no.1
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    • pp.11-18
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    • 2019
  • Purpose: This study verifies the muscle activity around the amputation site during proprioceptive neuromuscular facilitation (PNF) pattern exercise for the upper extremities on the non-amputated part in upper extremity amputees and provides basic data on effective exercise around an amputation site. Methods: Manual resistance was applied to the PNF upper extremity pattern of the non-amputated part to generate muscle activity around the amputation site. The resistance was adjusted to an intensity that could cause maximal isometric contraction. The muscle activity of the amputation site and the non-amputated part was measured using a surface electromyogram for the upper trapezius, middle trapezius, infraspinatus, serratus anterior, and pectoralis major. Results: During the scapular exercise in the painless range, the amputated side showed significantly lower muscle activity and a lower muscle contraction ratio compared with the non-amputated side. During the PNF pattern exercise in the painless range, the amputated side showed lower muscle activity and a lower muscle contraction ratio compared with the non-amputated side. When the direct scapular exercise of the amputated side was compared with the PNF pattern exercise of the non-amputated side, their muscle contraction ratios were similar. Conclusion: This study confirmed the effectiveness of the PNF pattern exercise of the non-amputated part as a way to indirectly train the injured site with no pain for rehabilitation of patients with serious body injuries, such as amputation. It is necessary to develop effective exercise programs for the rehabilitation of the amputation site based on the results of this study.

Mini open repair of the rotator cuff tear (회전근 개 파열에 대한 소절개를 이용한 봉합술)

  • Rhee Yong Girl
    • Journal of Korean Orthopaedic Sports Medicine
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    • v.3 no.2
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    • pp.98-99
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    • 2004
  • 소절개 봉합술은 관혈적 봉합술에 비해 동반된 관절와 상완 관절(glenohumeral joint) 내의 병변을 확인하고 이에 대한 처치를 시행할 수 있으며, 견봉하 감압술과 함께 동반된 견봉 쇄골 관절의 병변을 치료할 수 있다. 또한 삼각근 기시부에 대한 손상을 최소화하기 때문에 빠른 재활과 조기 퇴원을 시행할 수 있는 등의 장점이 있다 관절경적 봉합술에 비해서는 수술 술기가 어렵지 않기 때문에 항상 좋은 결과를 기대할 수 있다 회전근 개 파열에 대한 수술을 시행할 때 관절경적 봉합술이 모든 경우에서 관혈적 또는 소절개 봉합술에 비해 좋은 결과를 나타내는 것은 아니다. 환자가 심한 골다공증이 있는 경우, 기술적 문제가 있는 경우, 봉합 후 회전근 개에 지나친 긴장이 염려될 때는 항상 소절개 봉합술로의 전환을 시도하여야 한다. 소절개 봉합술을 시행한 경우에도 관절경적 봉합술시와 비슷한 좋은 결과를 얻을 수 있고, 치료의 결과는 수술의 방법보다는 정확한 술기 및 수술 전 환자의 상태에 좌우된다고 하겠다.

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Usefulness of Multiphase Scaffolds for Improving Tendon to Bone Healing for Rotator Cuff Tears in Shoulder (회전근개파열에서 힘줄뼈부착부 개선을 위한 다상 스캐폴드의 유용성)

  • Lee, Sang Chul
    • Clinical Pain
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    • v.19 no.2
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    • pp.59-63
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    • 2020
  • Rotator cuff tear is often cited as a reason for shoulder pain and dysfunction in patients > 40 years of age. Surgical repair of rotator cuff tear is one of the most commonly performed orthopedic surgical procedures. Until now, the success rate of surgical repair for rotator cuff tear has not been satisfactory. Many factors influence the process of rotator cuff repair such as the presence of tendinosis and fatty infiltration, but the main factor is the difficulty in achieving healing at the tendon to bone interface. There is a clinical need for bioengineering approaches to promote regeneration of the native enthesis and reduce the poor outcomes after surgical repair. Toward this end, the design and fabrication of multiphasic or hierarchically structured scaffolds have received great attention. This manuscript deals with information on the tendon to bone interface and tries to find out why a multiphasic scaffold is necessary to reproduce it and considerations that need to be taken into to make an ideal scaffold.

Arthroscopic ACL Reconstruction Using Quadrupled Hamstring Tendon with Tibial Remnant-preserving Technique (슬괵건을 이용하여 경골부 잔류 조직을 보존한 관절경적 전방십자인대 재건술)

  • Kyung, Hee-Soo;Oh, Chang-Wug;Kim, Poong-Taek;Lee, Byung-Woo
    • Journal of Korean Orthopaedic Sports Medicine
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    • v.6 no.2
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    • pp.92-98
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    • 2007
  • Purpose: We evaluated the clinical results of arthroscopic ACL reconstruction using quadrupled hamstring tendon with tibial remnant-preserving technique. Materials and Methods: Thirty-five cases were evaluated from Feb, 2003 to May, 2006. The average interval from injury to surgery was $2.6{\pm}1.6$ months. The cause of injury was mostly sports-related trauma. The average follow-up period was 17 months. Tibial remnant was preserved as much as possible and caution was taken not to damage the remnant during ACL reconstruction. Postoperative rehabilitation was the same as the usual rehabilitation method after ACL reconstruction, except for delaying motion for 2 weeks with an extension locking brace. Clinical evaluation was performed using ROM; Lachman test; pivot-shift test; anterior displacement measurement using KT-2000 arthrometer; Lysholm score and proprioception measured by single limb standing test. Results: There was no limitation of knee motion without contracture. The Lachman test and pivot-shift test were both negative. The side-to-side difference of anterior displacement measured using KT-2000 arthrometer was improved from 6.7 mm to 2.2 mm. The average Lysholm score improved from 81 to 96. The single limb standing test for proprioceptive evaluation showed no significant difference from a normal leg. Conclusion: ACL reconstruction with tibial remnant-preserving technique can preserve mechanoreceptors with prorioception and expect good functional recovery.

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Comparisons of Anxiety, Sexual Attitudes and Behaviors According to Smartphone Use and Contacts with Obscene Materials in University Students (대학생의 스마트 폰 사용 및 음란물 접촉에 따른 불안, 성 태도, 행동 비교)

  • Moon, Jong-Hoon;Jeon, Min-Jae;Lee, Chang-Hyung
    • Journal of Korea Entertainment Industry Association
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    • v.13 no.5
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    • pp.203-213
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    • 2019
  • The purpose of this study was to compare the anxiety, sexual attitudes, and sexual behavior according to smartphone use and contacts with obscene materials. 110 university students surveyed demographic characteristics, smartphone use, contacts with obscene materials, anxiety, sexual attitudes, and sexual behavior, and analyzed 102 questionnaires except missing and incomplete responses. The collected data were analyzed by independent t-test or chi-square test. Men were significantly more likely to have contacts with obscene materials, sexual attitudes, and sexual behavior than the women (p<.05). In type of residence, boarding room or lodging was significantly higher at time of smartphone use, anxiety, and sexual behaviors than the home (p<.05). There was no difference in variables according to religion (p>.05). There was no difference in variables according to the level of academic achievement (p>.05). Time of smartphone use over 3 hours was significantly higher for contacts of obscene materials, anxiety, and sexual attitudes and behaviors than less 3 hours (p<.05). Higher levels of time of contacts with obscene materials were significantly higher in anxiety and sexual behaviors than lower level (p<.05). The results of this study can be used as a basis for the development of intervention programs for those who are experiencing excessive smartphone use and contacts with obscene materials.

Methods of medical treatment in 『Euibangyoochui』 (『의방유취(醫方類聚)』치법편의 구성과 특징 -식치(食治)·금기(禁忌)·침구(鍼灸)·도인편(導引篇)을 중심으로-)

  • Ahn, Sang woo;Choi, Whan soo
    • The Journal of Korean Medical History
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    • v.14 no.1
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    • pp.109-124
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    • 2001
  • "Euibangyoochui" is a great medical encyclopedia composed of 91 symptoms and signs of diseases which classified 150 kinds of reference books. It consisted mainly of fifty thousands of herbal prescriptions and therapeutics but it deals with other treatments like diet therapy, precautions, acupuncture and moxibustion, physical and breathing exercises as well. Unlike other medical references, this book made up these treatments as independent chapters. We tried to catch the meanings and characteristics of each chapters.

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Clinical Case Report on the Gait disturbance Patient with Osteoporosis and Lower Limb Fracture Surgery Treated by Chuna Therapy (골다공증을 동반한 하지부골절 수술 후 보행불리 환자 재활에 단순추나요법을 적용한 치험 1례)

  • Lee, Yun-Jin;Park, Na-Ri;Yang, Doo-Hwa;Ahn, Hee-Duk
    • The Journal of Churna Manual Medicine for Spine and Nerves
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    • v.14 no.2
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    • pp.77-88
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    • 2019
  • Objectives : The purpose of this study was to show the effectiveness of Chuna Manual Therapy applied to a osteoporosis patient with gait disturbance due to lower limb fracture surgery. Method : We focused on Chuna therapy accompanied with acupuncture, herbal medicine, moxibustion, cupping treatment and rehabilitation exercise. This case was assessed using the Visual Analogue Scale (VAS), Pain Free Walking Distance (PFWD), Berg Balance Scale (BBS), and Modified Barthel Index (MBI). Result : This patient showed improvement on the VAS from 6 to 3, PFWD from 0 m to 2000 m using a walker and 50 m by self-walking, BBS from 2 to 28, and MBI from 56 to 89. Moreover the walking state improved from gait disturbance to self-walking. Conclusion : This study suggests that Chuna therapy could be used to improve gait disturbance in patients with osteoporosis and lower limb fracture surgery.

Sports Pharmacy: New Specialty of Pharmacists and Pharmaceutical Care Services (스포츠 약학: 새로운 영역의 약사 역할과 전문 약료서비스 준비)

  • Kim, Sung Hwa;Cho, Sora;Choi, Jae Hee;Lee, Young-Hee;Rhie, Sandy Jeong
    • Korean Journal of Clinical Pharmacy
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    • v.31 no.1
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    • pp.12-20
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    • 2021
  • The World Anti-Doping Agency has made efforts to promote the safe use of medications and prevent doping in sports globally. International standards have been established and experts have advocate anti-doping education to athletes and healthcare professionals. Pharmacists are expected to participate in the pharmaceutical care activity of sports medicine in protecting the athletes while providing the spirits of clean sports. In this review, we described the pharmacists' roles and functions in six areas of sports pharmaceutical care: awareness, treatment, prevention, optimization, abuse, and monitoring. Sports pharmacists should be able to prevent inappropriate drug use and manage athletes' illness and injury using pharmacotherapy. Further pharmacists should actively involve to educate and counsel athletes, trainers, and healthcare teams. In conclusion, pharmacists are expected to play important roles in sports pharmacy, which is the emerging area of specialized pharmaceutical care services.