• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.11 no.2
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• pp.110-115
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• 2008

Purpose: Intussusceptions are one of the most common causes of intestinal obstruction in infants and young children. Although it is easily treated by non-operative reduction using barium, water or air, this treatment is very stressful for young patients and may cause bowel perforation, peritonitis and shock. In this study, we identified the risk factors associated with the failure of non-operative reduction, to identify a group of children that would benefit from the procedure and those who would not. Methods: We reviewed the medical records of patients with intussusception who were treated at the Korea University Medical Center Ansan hospital from March 1998 to July 2006. Three hundred fourteen children with intussusception were identified. Among them, non-operative reductions were performed in three hundred. Clinical and radiological variables were compared according to the failure or success of the non-operative reduction. Results: Non-operative reductions were successful in 243 (81%) and failed in 57 (19%). The group that had failed procedures had a younger age (12.3${\pm}$17.2 months vs. 18.0${\pm}$15.8 months, p=0.03), longer symptom duration before reduction (33.6${\pm}$29.0 hr vs. 21.5${\pm}$20.3 hr, p<0.01), more vomiting and lethargy (p<0.01), but less abdominal pain and irritability (p<0.01), compared with the group that had a successful procedure. Logistic regression analysis showed that the factors associated with the failure of non-operative reductions were a younger age, less than 6 months of age (odds ratio: 2.5, 95% confidence interval: 1.2~5.2, p=0.01), duration of symptoms, longer than 24 hrs before reduction (odds ratio: 2.1, 95% confidence interval: 1.2~4.2, p=0.03), bloody stool (odds ratio: 4.8, 95% confidence interval: 1.9~12.2, p<0.01), lethargy (odds ratio: 3.4, 95% confidence interval: 1.1~10.4, p=0.04), and abdominal pain or irritability (odds ratio: 0.2, 95% confidence interval: 0.1~0.4, p<0.01). Conclusion: For children with intussusception, an age younger than 6 months, and duration of symptoms more than 24 hrs before reduction, as well as the presence of bloody stools, lethargy and abdominal pain or irritability were variables associated with failure of a non-operative reduction. Knowledge of these variables should be considered in making clinical decisions for therapeutic interventions.

• Clinical and Experimental Pediatrics
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• v.52 no.3
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• pp.295-302
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• 2009

Purpose : To report our experience of gastrointestinal (GI) operations (OP) performed in very low birth weight infants (VLBWI) and to evaluate their clinical characteristics. Methods : Among the 1,117 VLBWI admitted to the SMC neonatal intensive care unit from November 1994 to February 2007, the medical records of 37 infants who underwent GI OP (except inguinal hernia OP) and 1,080 VLBWI without GI OP were retrospectively reviewed. Results : The mean gestational age ($27^{+6}2^{+3}$ vs. $28^{+5}{\pm}$2^{+6}$) and birth weight (979${\pm}$241 g vs. 1,071${\pm}$271 g) of the 37 VLBWI who underwent the GI OP was lower than the VLBWI without GI OP group (n=1,080). Mortality rates in the GI OP group were significantly higher than in the non GI OP group (28% vs. 15%, P<0.001). The incidence of cholestasis, retinopathy of prematurity and periventricular leukomalacia were higher in the GI OP group than in the non GI OP group, but the incidence of bronchopulmonary dysplasia was not significantly different between the GI OP group and the non GI OP group. For GI OP indications, focal intestinal perforation was most common and showed a more favorable outcome than necrotizing enterocolitis. Compared with an earlier 7-year period, 1994-2000, the incidence and survival rates increased in the subsequent 2001-2007 period. Conclusion : GI OP was associated with high mortality and morbidity in VLBWI. Further efforts to improve outcomes of GI OP in VLBWI should be investigated to improve the quality of care in VLBWI.

• 한국지구물리탐사학회:학술대회논문집
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• 2005.05a
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• pp.87-92
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• 2005

The ground-motion (GM) attenuation relations available in Korea has required the validation process for large earthquakes since most of them were developed based on small earthquake database, The Fukuoka earthquake (M=7.0) that occurred near the Korean Peninsula provides invaluable data to indirectly evaluate the attenuation characteristics of the strong GM in Korea. The GM levels (PGA, SA) obtained from the KIK-net downhole stations near the epicenter (R<100km) are reasonably predicted by the GM attenuation relation developed by KEPRI in 2003 for the Kori NPP site, the result of which validates the use of KEPRI GM attenuation relation for predicting GM induced by future large earthquakes. Also, the comparison between the Osaki spectra and response spectra of KIK-net downhole data reveals that the amplitude levels of Osaki spectra are higher than the spectra from KIK-net stations which are believed to be installed at the seismic basement.

• Journal of the Korean Geophysical Society
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• v.8 no.3
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• pp.109-113
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• 2005

The ground-motion (GM) attenuation relations available in Korea has required the validation process for large earthquakes since most of them were developed based on small earthquake database. The Fukuoka earthquake (M=7.0) that occurred near the Korean Peninsula provides invaluable data to indirectly evaluate the attenuation characteristics of the strong GM in Korea. The GM levels (PGA, SA) obtained from the KIK-net downhole stations near the epicenter (R<100km) are reasonably predicted by the GM attenuation relation developed by KEPRI in 2003 for the Kori NPP site, the result of which validates the use of KEPRI GM attenuation relation for predicting GM induced by future large earthquakes. Also, the comparison between the Osaki spectra and response spectra of KIK-net downhole data reveals that the amplitude levels of Osaki spectra are higher than the spectra from KIK-net stations which are believed to be installed at the seismic basement.

• The Journal of Engineering Geology
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• v.17 no.1 s.50
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• pp.27-40
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• 2007

Stratigraphy has been renewedly set up and the evolution of tectonic events related to basin formation has been exam-ined on the basis of fault-slip data analysis in the Tertiary Eoil and Waeup basins of the southeastern part of Korea. First of all, field mapping was carried out in detail for Tertiary formations and then paleostress analysis were peformed with more than 400 fault slip data collected from 11 sites in the Tertiary formations and the Yucheon Group. It is judged that both the Eoil and Waeup basins filled up with Tertiary deposits might be simultaneously formed in separate locations. The Janggi Group in the Eoil basin is divided into following stratigraphic units in ascending order: Gampo Conglomerte, Hongdeok Basalt, Nodongri Conglomerate and Yeondang Basalt, and the Bomkori Group in the Waeup basin: Waeupri Tuff; Andongri Conglomerate, Yongdongri Tuff and Hoamri Volcanic Breccia. Paleostress analysis by using striated faults reveals five sequential tectonic events: (1) NW-SE transtension (event I), (2) NW-SE transpression (event IIl), (3) NE-SW pure extension (event III), (4) N-S transpression (event IV) and (5) E-W pure compression (event V). Therefore, five sequential tectonic movements are closely associated with the formation and evolution of the Tertiary basins in the study area: tectonic event I of NW-SE extension is related to formation of the Tertiary basins during the late Oligocene to the Early Miocene, tectonic events II, III and IV caused the termination of the Tertiary basin opening and the crustal uplift in the study area, and tectonic event V upheaved the east coast or Korean Peninsula with compressive stress due to intense subduction of the Pacific plate into Asian continent since the Early Pliocene.

• 한국지구물리탐사학회:학술대회논문집
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• 2005.05a
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• pp.79-86
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• 2005

The apparent source spectrum of the Fukuoka earthquake is estimated at the seismic basement by removing from the observed spectra at Korean seismic stations the path and site responses that were previously revealed through inversion process applied to large spectral D/B accumulated until 2004. The approximate source spectrum is also estimated by using data recorded near the epicenter from various Japanese seismic networks and compared with the Korean source spectrum. The comparison result shows that there is good agreement among source spectra estimated based on the data from seismic networks of Korea at large distances (190km

• The Journal of Engineering Geology
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• v.8 no.1
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• pp.35-49
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• 1998

To interpret the movement historv of the Yangsan fault, the paleostresses were analyzed from about 1,000 striated small faults and 330 extension joints which were measured from 37 sites near and along the strike of the Yangsan fault from Yangsan-si, Kyeongsangnam-do to the Shinkwang-myeon, Kyeongsangbuk-do. Six sequential tectonic events have boen established as followings: (I) NW-SE extension, (Il) ENE-WSW compression and NNW-SSE extension, (III) NW-SE compression, (W) ENE-WSW extension, (V) E-W comoression and N-S extension, and (VI) NNE-SSW compression and(VI) NNE-SSWextension. The movement history of the Yangsan fault rnrning in NNE direction were inteepreted based on these six sequential stress fields. The initial feature of the Yangsan fault was formed at the first stage with the development of extension fractures by tectonic event (I) of NW-SE extension. The fault was acted continuously with a right-1ateral strike-slip movement by tectonic event( II) closely related to event( I). The movements had been continued until the Late Miocene. This age was the most active period in faulting. The left-lateral strike-slip movement was followed by subsequent tectonic events (ffi) and (IV). The activity of the Yangsan fault was suspended temporarily by compression of tectonic event (V) which was perpendicular to the strike of the fault. This period might be very short and the magnitude of the tectonic was also small. In the last stage, the fault acted with slight extension or right-lateral moveenent by tectonic event (VI).

• Journal of the Korean Geophysical Society
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• v.8 no.1
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• pp.15-21
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• 2005

The apparent source spectrum of the Fukuoka earthquake is estimated at the seismic basement by removing from the observed spectra at Korean seismic stations the path and site responses that were previously revealed through inversion process applied to large spectral D/B accumulated until 2004. The approximate source spectrum is also estimated by using data recorded near the epicenter from various Japanese seismic networks and compared with the Korean source spectrum. The comparison result shows that there is good agreement among source spectra estimated based on the data from seismic networks of Korea at large distances (190 km

• Radiation Oncology Journal
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• v.16 no.3
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• pp.311-323
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• 1998

Purpose : Prospective, single arm, Phase I/II clinical trial was performed to assess the efficacy and toxicity of the concurrent chemotherapy and definitive radiotherapy (RT) in patients with previously untreated locally advanced carcinoma of the uterine cervix. Methods and Materials : From Mar 1992 to January 1997, a total of 73 patients with advanced cervical carcinoma were entered on the protocol but 5 patients were excluded in analysis because of patients' refusal of treatment. Their ages ranged from 31 to 77 years, median 58 years. The International Federation of Gynecology and Obstetrics (FIGO) stage distribution was as follows: IIB 46, IIIA 2, IIIB 15 and IVA 5. RT consisted of external beam irradiation to 4,140-5,040 cGy/23-28 fractions plus high dose rate intracavitary treatments to deliver a dose of 30-35 Gy to point A in 6-7 fractions. During the intracavitary treatments parametrial boost was delivered for point B dose of 60 Gy in stage IIB and 65 Gy in stage IIIB. Two cycles of concurrent 5-fluorouracil and cisplatin (FP) chemotherapy (5-fluorouracil 1,000 mg/$m^2$/day continuous infusion for 4 days, day 1-4, 29-32 and cisplatin 20 mg/$m^2$/day intravenous bolus for 3 days day 1-3, 29-31) administered starting on day 1 of RT. Results : The median follow-up was 24 months (range 4-68+). Sixty-four patients were evaluable for survival rate in this protocol: The 5-year actuarial and disease-free survival rate were 52$\%$ and 64$\%$, respectively. The 5-rear actuarial survival for stage IIB and III+IVA patients were 58$\%$ and 36$\%$, respectively The 5-year disease-free survival rate for stage IIB and III+IVA patients were 71$\%$ and 40$\%$, respectively. Of the 68 patients evaluated for patterns of failure, overall recurrence rate was 27.9$\%$ (19/68) : local failure in 5.9$\%$ (4/68), distant metastasis in 10.3$\%$ (7/68) and both in 11.8$\%$ (8/68). Of the 64 patients evaluated for response at one month after the completion of treatment the complete response rate was 78$\%$ (50/64). Concurrent chemoradiation appear to be a well-tolerated regimen but there were two treatment-related deaths. Conclusion : Concurrent chemotherapy of FP with high-dose definitive RT in locally advanced carcinoma of the uterine cervix is feasible and effective with acceptable toxicities. This chemoradiation regimen may offer a modest survival benefit for advanced stage. Further follow-up of these patients will evaluate the impact of this regimen on the long-term local control and their survival.