• The Korean Journal of Applied Statistics
• /
• v.29 no.7
• /
• pp.1247-1255
• /
• 2016

Kim and Lee (2015) identified a superior FABP4 gene that improves the grade and fatty acid of Korean cattle. This study selects a superior genotype by expanding genes that influence the economic traits of Korean cattle. Expanded genes are FABP4, SCD, FASN and SREBPs that are related to grade and fatty acid (Oh, 2014). We use the adjusted economic-trait values with environmental factors excluded. We also applied multifactor dimensionality reduction(MDR) method to data of the adjusted economic-trait values. As a result, we identified superior genes and genotypes which improved the grade and fatty acid of Korean cattle.

• Journal of the Korea Institute of Information and Communication Engineering
• /
• v.13 no.1
• /
• pp.1-5
• /
• 2009

In this paper, a novel wideband crossed planar monopole antenna with the multiple resonance characteristics is proposed. The proposed monopole antenna can be designed by a wideband crossed planar monopole antenna with L-shaped slits. In order to generate multiple resonance characteristics on the proposed monopole antenna, the length of L-shaped slit and the number of L-shaped slits are determined at an interesting frequency. The proposed antenna having an omnidirectional radiation pattern and a high gain over the multiple resonance frequency bands, respectively, is suitable for a mobile antenna.

• Journal of the Korea Institute of Information and Communication Engineering
• /
• v.15 no.3
• /
• pp.536-544
• /
• 2011

In this paper, a controller for two wheeled inverted pendulum type robot is designed to have more stable balancing capability than conventional controllers. Traditional PID control structure is chosen for the two wheeled inverted pendulum type robot, and proper gains for the controller are obtained for specified user's weights using trial-and-error methods. Next a neural network is employed to generate PID controller gains for more stable control performance when the user's weight is arbitrarily selected. Through simulation studies we find that the designed controller using the neural network is superior to the conventional PID controller.

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.30 no.4A
• /
• pp.320-327
• /
• 2005

In this paper, compensation structures are proposed in the CPW directional couplers with finite-extent backed conductor for tight coupling. The proposed structures are realized T-shaped expanded slots and modified finite-extent backed conductor in CPW coupled structure. The T-shaped expanded slots was used to avoide reduced coupling and modified finite extent backed conductor of dumbbell shape was used to enhance directivity and matching. The designed CPW directional couplers at 1 GHz has good directivity without reducing coupling in simulation by EM solver based on full-wave analysis and measurements.

• Journal of the Korea institute for structural maintenance and inspection
• /
• v.13 no.4 s.56
• /
• pp.148-158
• /
• 2009

Firstly the problems of existing foreign code concerning wheel load distribution factor for skew box girder bridges have been examined, and the main parameters which have effects on wheel load distribution factors are evaluated in this study. Further finite element analyses on various skew steel box girder bridges are carried out. Based on the analysis results, formulas to determine wheel load distribution factors are proposed using multiple regression analysis. It is found when using the proposed formulas in this study weak points of existing specifications could be improved and also time spent at structural analysis should be saved a lot, so that the validity and practicality could be verified.

• Journal of Embryo Transfer
• /
• v.22 no.3
• /
• pp.167-172
• /
• 2007

Pituitary-specific transcription factor (PIT1) 유전자는 동물의 성장을 조절하고 근육 형성에 관여하는 유전자로서 최근에는 단일염기다형성 변이가 한우를 비롯한 동물에서 관찰되었으며, 한우의 경제 형질과 연관성이 보고되었다. 본 연구는 PIT1 유전자의 단일염기다형성 변이가 한우에서 성장 인자에 미치는 영향과 경제 형질에 대한 유전자형간 육종가와의 상관성에 대해 알아보고자 하였다. 도체 성적을 보유하고 있는 한우 후보종모우 집단 268두를 대상으로 PIT1 유전자 A1256G 다형성을 조사하여 유전자형의 빈도를 분석하였고 각각의 유전형에 따른 기본적인 검정 성적을 바탕으로 경제 형질과의 연관성을 비교 분석하였다. 268두의 한우에서 PIT1 유전자의 A1256G 유전자형 빈도는 MseI 제한 효소를 사용했을 때 A 유전자 빈도(0.37)보다 G 유전자 빈도(0.62)가 높게 나타났다. 통계적 분석을 통하여 각 유전자형에 대한 경제 형질과의 관련성을 분석한 결과, 각 유전자형 간에 12개월령 체중 (body weight 12, BW12)에서 유의한 차이를 보였고, 등지방 두께 육종가 (Backfat thickness-estimated breeding value, BF-EBV)와도 유의한 차이가 있었지만 (p<0.05), marbling score (MS), carcass weight (CW), M. longissimus dorsi area (LDA) 등 다른 경제 형질과는 통계학적으로 유의한 차이가 없었다. PIT1 유전자의 A1256G 다형성은 한우의 성장과 도체체중에 관여하는 인자로 작용하는 것으로 보여진다.

• Journal of the Korea Society of Computer and Information
• /
• v.3 no.2
• /
• pp.1-6
• /
• 1998

The evaluation of reliability is very important in the development process of software. There may be lack of trustfulness on the results that come from the analysis and evaluation of reliability of softwares which do not divide the test phases. At this point, this article studies how to evaluate the reliability dividing the test phases in order to settle the these problems. In doing so, I apply the fault data to be found in Unit Test, Integration Test, Validation Test and System Test to SRGM(Software Reliability Growth Model), Exponential SRGM, Delayed S-shaped SRGM and Inflection S-shaped SRGM. The result is that Inflection S-shaped is best suitable with Unit Test Delayed S-shaped is best suitable with Integration and Validation Test, and Exponential SRGM is best suitable with System test. In this respect, I can show that the results of this study on parameter estimation, difference square summation, number of fault remained is superior to the established methods.

• Korean Journal of Agricultural Science
• /
• v.20 no.1
• /
• pp.56-67
• /
• 1993

To applying of genetic markers of milk proteins as dairy cow registration and selection aids for genetic improvement, genopypes controlling the 4 milk protein loci, ${\alpha}S1$-casein (${\alpha}S1$-CN), ${\beta}$-casein(${\beta}$-CN), ${\kappa}$-casein(${\kappa}$-CN), and ${\beta}$-lactoglobulin(${\beta}$-LG), from a total of 159 Holstein lactating cows reared at National Animal Breeding Station in 1992 were detected by polyacrylamide gel(PAGE) electrophoresis, and associations between genetic polymorphisms of milk proteins and milk compositions were analyzed. The observed distribution of phenotypes for ${\alpha}S1$-CN, ${\beta}$-CN, ${\kappa}$-CN and ${\beta}$-LG were agreement with those expected under the assumption of genetic equilibrium. The observed genotypic frequencies of the ${\alpha}S1$-CN BB, ${\beta}$-CN AA, ${\kappa}$-CN AA and ${\beta}$-LG AB genotypes were founded to be very high as 79.87%, 84.28%, 71.70% and 49.10%, respectively. Gene frequencies were 0.899 and 0.101 for ${\alpha}S1-CN^B$ and ${\alpha}S1-CN^C$, 0.921 and 0.079 for ${\beta}-CN^A$ and ${\beta}-CN^B$, 0.837 and 0.163 for ${\kappa}-CN^A$ and ${\kappa}-CN^B$, 0.378 and 0.622 for ${\beta}-LG^A$ and ${\beta}-CN^B$. According to the results of analysis of variance, the genotypes of the ${\alpha}S1-CN$, ${\beta}-CN$, ${\kappa}-CN$ and ${\beta}-LG$ were significantly difference for fat, protein and total solid percentage in milk compositions. On milk compositions, the ${\kappa}$-CN BB genotype was very high fat and protein percentage more than ${\kappa}$-CN AA and AB genotypes, and ${\beta}$-LG AA genotype was very high fat percentage more than ${\beta}$-LG AB and BB genotype at 5% level of significant difference, respectively. As a consequence, the fat and protein percentage may be improved to select to ${\kappa}$-CN BB and ${\beta}$-LG AA genotypes.

• Clinical and Experimental Pediatrics
• /
• v.52 no.3
• /
• pp.356-363
• /
• 2009

Purpose : A polymorphism in the IGF-I gene promoter region is known to be associated with serum IGF-I levels, birth weight, and body length, suggesting that IGF-I gene polymorphism might influence postnatal growth. The present study aimed to investigate the role of this polymorphic cytosine-adenine (CA) repeat of the IGF-I gene in children with idiopathic short stature. Methods : The study involved 131 children (72 boys and 59 girls) diagnosed with idiopathic short stature, aged 715 years. Genomic DNA was extracted from anticoagulated peripheral whole blood. The primers were designed to cover the promoter region containing the polymorphic CA repeat. Data were analyzed using GeneMapper software. The correlations between age and serum IGF-I levels were analyzed using Spearmans correlation coefficient. Results : The CA repeat sequences ranged from 15 to 22, with 19 CA repeats the most common with an allele frequency of 40.6%. Homozygous for 19 CA repeat was 13.0%, heterozygous for 19 CA repeat was 56.5%, and 19 CA non-carrier was 30.5%. The three different genotype groups showed no significant differences in height, body weight and body mass index, and serum IGF-I levels. The serum IGF-I level and age according to the IGF-I genotypes were significantly correlated in the entire group, 19 CA repeat carrier group, and the non-carrier group. The three groups also showed no significant differences in the first year responsiveness to GH treatment. Conclusion : There were no significant different correlations between 19 CA repeat polymorphism and serum IGF-I levels according to genotype. Our results suggest that the IGF-I 19 CA repeat gene polymorphism is not functional in children with idiopathic short stature.

• Journal of Animal Science and Technology
• /
• v.53 no.2
• /
• pp.107-111
• /
• 2011

This study was undertaken to reveal the relationship between genetic variations and the basic coat color classification system in Jeju horses. Genetic variations of the melanocortinreceptor 1 (MC1R) and agouti signaling protein (ASIP) genes were investigated using pyrosequencing technique. A nucleotide substitution mutation for MC1R g.901C>T and an ASIP 11-bp deletion mutation were screened. Black horses had MC1R $E^+$/- ($E^+/E^+$ or $E^+/E^e$) and ASIP $A^a/A^a$ genotypes. In contrast, chestnut horse genotypes were MC1R $E^e/E^e$ and ASIP -/-. Thus, black and bay horses have at least one dominant MC1R allele, $E^+$, whereas chestnut horses have homozygous recessive alleles $E^e/E^e$. This suggests that the MC1R genotypes determine chestnut or black/bay coat color, regardless of the genotype distribution of ASIP. In addition, the horses with MC1R $E^+$/- and a dominant ASIP $A^A$/- allele showed bay coat color, but not black, suggesting that the ASIP $A^A$ allele represses black coat color development in the hairs of the body, but not in the mane and all four legs. Pedigree analysis showed a consistent relationship between the genotype distribution of the MC1R and ASIP genes and basic coat color patterns, even in the $F_1$ progeny. The results of this study revealed the relationship between the coat color phenotype and genetic background and suggested that useful information may be provided for molecular breeding of Jeju horses.