• KOREAN JOURNAL OF CROP SCIENCE
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• v.22 no.1
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• pp.11-15
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• 1977

Natural infection of purple stain seemed to be higher in early maturing lines comparing to late maturing group. It was positively correlated with length of the period from flowering to maturity and significantly associated with weather conditions during the maturing period.

• Parasites, Hosts and Diseases
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• v.31 no.3
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• pp.239-248
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• 1993

The purpose of this observation was to investigate the natural killer cell activities in mice Infected with pathogenic free-living amoeba, Naegleria fowleri and Acanthomoeba culbertsoni according to the infection doses, and infected with non-pathogenic free-living amoeba, Naegleria fowleri. The natural killer cell activity was examined by means of target binding capacity, active NK cell and maximum recycling capacity of the mice after inoculating free-living amoebae with low and high doses. The mice infected with 1 103, 1 105 A. culbertsoni trophozoites showed mortality rates of 6.9% and 65.5%, respectively. The mice infected with 1 104, 1 105 N.fowleri trophozoites showed mortality rates of 5.9% and 72.2%, respectively. The NK cell activities in all experimental groups increased significantly on day 1 after infection as compared with control group, and then remarkably declined thereafter, there was no difference of the cytotoxic activity of the NK cells In mice among inoculation doses of pathogenic free-living amoebae. The target binding capacities of NK cells and percentages of activated NK cells in mice Infected with pathogenic free-living amoebae were slgrlificantly Increased a day after Infection, as compared Uth control group. There was no difference of the maximal recycling capacities of NK cells in all experimental groups as compared Uth control group. There was significant difference in the cytotoxic activity and single cell cytotoxlcity of NK cells between the experimental groups infected with pathogenic free-living amoebae and that infected with non-pathogenic free-living amoebae.

• Journal of Veterinary Clinics
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• v.17 no.1
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• pp.1-5
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• 2000

Microsporum gypseum을 인공감염시킨 기니픽에서 terbinafine의 치료효과 실험을 위한 전단계 실험으로서 인공감염시킨 기니픽에서 M. gyspeum의 생물학적 주기를 조사하였는데, 이것은 인공감염된 후 효과적인 치료와 평가의 시기를 결정하기 위해 필요하였다. M. gypseum으로 인공감염된 기니픽의 생물학적 주기는 급성기 이후에 자연치유되는 것이 특징이었다. 증식기는 감염 후 5일부터 11일까지 지속되었다. 따라서 다음 번의 치료효과 실험에서 인공감염 당일부터 9일간 계속 terbinafine을 경구투구하고, 마지막 투여 다음 날 진균학적 및 임상적 평가를 하기로 결정하였다.

• Parasites, Hosts and Diseases
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• v.30 no.1
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• pp.21-24
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• 1992

The infectivity of metacestodes of Asian Taenia saginata, now tentatively called Taenia saginata taiwanensis, in human host was confirmed. The metacestodes used in experimental infection were collected from the livers of naturally infected domestic pigs at an abattoir in Cheongju City, Korea. The first gravid proglottid was spontaneously discharged 76 days after infection. Two worms were recovered two years later by chemotherapy. The scolex was unarmed. The number of main uterine branches, varying from 16 to 21, was similar to that of classical Taenia saginata. The liver of pigs was confirmed to be an infection source of Asian T. saginata in Korea.

• Korean Journal of Veterinary Research
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• v.38 no.3
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• pp.600-605
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• 1998

춘천지역에서 포획한 한국 야생랫드(시궁쥐)에서 Capillaria hepatica에 자연감염된 예를 보고한다. Capillaria hepatica의 충란이 포획된 68마리의 랫드중 17마리에서 발견되었다. Capillaria에 감염된 랫드의 간장은 충란과 함께 림프구, 단핵구, 호산구의 침윤이 관찰되었고 심한 괴사소견을 보였다. 또한 섬유화, 출혈 hemosiderin의 침착이 뚜렷하게 관찰되었다. 최근 국내에서 자연에서 채집된 랫드의 Capillaria hepatica의 감염을 보고한 자료가 없는 것으로 미루어 Capillaria hepatica의 숙주감염을 파악하는 자료로 활용될 수 있을 것이다.

• Korean Journal of Microbiology
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• v.31 no.2
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• pp.113-122
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• 1993

Aeromonas veronii was isolated from the haemorrhagic ulcer of the snakehead that had been infected in natural condition, This bacterium was injected hypodermically into the healthy snakeheads and the effect was compared to the naturally infected fish. Both groups showed severe necrosis, falling off of epidermal tissue and hypodermal muscle. In both groups, severe histophathological changes were observed in gill, digestive tract and kidney just before death. Artificially injected fish showed necrosis of tissue in skin, gill and digestive tract from 2 days after injection. Then it showed necrosis or cell atrophy of tissue in kidney from 5 days after injection, and in liver and spleen just before death. Snakehead infected with haemorrhagic ulcer died within 9 days after infection, showing the symptom of skin damage and metabolic inhibition in respiration" digestion, excretion, etc. It was concluded that Aeromonas veronii (CA26) that was isolated from the naturally infected fish is the main bacterium causing haemorragic ulcer in the snakehead.

• Parasites, Hosts and Diseases
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• v.23 no.1
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• pp.173-174
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• 1985

1984년 11월에 쩐남 장홍군 장흥읍에서 구입한 은어에서 자연감염된 요꼬가와흠충의 피낭유충을 분리하여 개 2마리에 실험감염시키고, 감염후 4주일 및 8주일에 도살하여 성충을 얻었다. 그 과정중에서 감염 제8주에 도살한 개의 회장에서 인eterephyepsis continua로 동정한 충체 3마죄를 요꼬가와흡충과 함께 얻었다. 이들 충체는 은어에서 분리하여 감염시킨 괴낭유충 140,000개중에 섞여 있었던 것에서 유래 하였다고 판단하였다. 따라서 은어를 노. continua의 제이중간숙주로 추가하는 것이 타당하다고 생각한다. 은어가 강 하구 반염수대에서 겨울철을 넘기거나 어린시절을 보내므로 그때에 적게나마 감염되는 것으로 생각하였다. Heterephyepsis continua(Onji et Nishio, 1916)의 우리 말 이름을 "긴이형휸충"으로 할 것을 제의한다.

• Parasites, Hosts and Diseases
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• v.27 no.1
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• pp.23-34
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• 1989

In an attempt to investigate the effect of Hymenolepis dana infection on immunological responses to sRBC in ICR strain of mice, cellular and humoral immune responses were chronologically monitored after sensitization with sRBC. Mice weighing about 20 g were allocated into artificial and natural infection groups. The shell-free eggs of H. dana were inoculated into mice on the day 0 (initial) and day 10 in the former group, and praziquantel (25 mg/kg/day) was administered for 3 days to the one half of the mice at the 15th day after the first inoculation and to all of the mice in natural infection group. In artificial infection group, the delayed-type hypersensitivity (DTH) to sRBC was considerably decreased on the day 10 after the first inoculation, and then elevated gradually to normal. Eosinophils in the peripheral blood increased slightly. The hemagglutinin (HA) and hemolysin (HE) titers during the early stage were shown to be more or less higher than those of control. Thereafter, the titers were returned to normal, followed by a transient decrease on the day 15 post-infection. The sRBC rosette and antibody-treated rosette-forming capacities on the day 15 post.infection were temporarily lowered but became higher thereafter. The mucosal mast cells (MMC) in the small intestine were gradually increased to make a peak on the day 10 post-infection and then maintained more or less at lower level. After praziquantel treatment, the DTH and the number of eosinophils were decreased slightly and the MMC number and sRBC rosette-forming capacity were considerably decreased. The titers of HA and HE and antibody-treated rosette-forming capacity, however, were elevated in general. In natural infection group, the DTH, the number of eosinophils, and MMC which were elevated due to H. dana infection were gradually returned to normal after prasiquantel treatment. The titers of HA and HE which were decreased by parasite infection were increased to normal after the treatment. However, the capacities of sRBC rosette or antibody-treated rosette formation were maintained at low levels in spite of the treatment. These results revealed that the immune responses to sRBC were significantly activated during H. dana infection, although they were transiently decreased during the days 10~15 post-infection.

• Korean Journal of Veterinary Research
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• v.24 no.2
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• pp.237-243
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• 1984

한국에서 돼지에 감염되고 있는 Eperythrozoon 증양 질병의 역학적 생물학적 기초연구를 위해 본 질병에 자연감염 발병한 돼지 157두와 정상인 돼지 240두에 대하여 조사하였던 바 다음과 같은 결과를 얻었다. 혈액표본에서 관찰한 본 병원체의 감염율 형태 및 크기는 계절에 따라 변화를 보였는데, 정상인 돼지는 년평균 54% 감염율을 발병한 돼지는 모두 감염된 상태였다. 5종의 형태를 보이는 본병원체는 크기가 $0.5{\sim}0.5{\mu}$이었는 데 감염 혈액을 $0^{\circ}C$에 1주 이상(혹은 $-20^{\circ}C$에 24시간) 냉장하는 경우 그 크기가 $1.4{\sim}8.5{\mu}$까지 커졌으며 세포질내에 염색질 과립을 보이는 예도 발견되었다. 본 병원체는 적혈구막에 부착되거나 혈장내 유리된체 관찰되었으며 병든 돼지의 위장관과 방광내용물 중에서도 다수의 병원체가 발견되었다. 인공감염 실험에서 접종 감염된 돼지는 2개월간 경도의 체온상승과 빈혈상을 나타내면서 혈액내에 전형적인 병원체를 보유하였으며 접종시킨 쥐에서는 12개월이상 동일한 병원체의 잠복 감염상태를 유지하였다. 또한 병든 돼지 주위에서 포획한 파리와 모기의 장내용물 중에서 전형적인 본 병원체를 관찰할 수 있었다.

• Parasites, Hosts and Diseases
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• v.23 no.2
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• pp.197-202
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• 1985

During 8 April 1983 to 9 April 1985, a total of 181 domestic cats (Felis catus domestica Linnaeus) of unknown localities in Korea were purchased at Seoul Chung-ang market, and the internal organs were dissected for helminth infections. In the results, three kinds of trematodes of family Heterophyidae (Ohdner, 1914) were obtained from small intestine of domestic cats and identified as follows; five adult worms of Heterophyopsis continua (Onji et Nishio, 1916) from three hosts, two hundreds and twenty three adult worms of Pygidiopsis summa Onji et Nishio, 1916 from seven hosts and twenty six adult worms of Heterophyes heterophyes nocens (Onji et Nishio, 1916) from three hosts. Among them, Heterophyopsis continua and Pygidiopsis summa had not been proved as natural infections of cats in Korea.