• Journal of the Institute of Electronics Engineers of Korea SP
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• v.39 no.5
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• pp.544-555
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• 2002

The aim of this study is to develop the $^1H$-MRS data postprocessing software for both single-voxel and multi-voxel technique, which plays and important role as a diagnostic tool in clinical field. This software is based on graphical user interface(GUI) under windows operating system of personal computer(PC). In case of single-voxel MRS, both of raw data in time-domain and spectrum data in frequency-domain are simultaneously displayed in a screen. Several functions such as DC correction, zero filling, line broadening, Lorentz-Gauss filtering and phase correction, etc. are included to increase the quality of spectrum data. In case of multi-voxel analysis, spectroscopic image reconstructed by 3-D FFT was displayed as a spectral grid and overlapped over previously obtained T1- or T2-weighted image for the spectra to be spatially registered with the image. The analysis of MRS peaks were performed by obtaining the ratio of peak area. In single-voxel method, statistically processed peak-area ratios of MRS data obtained from normal human brain are presented. Using multi-voxel method, MR spectroscopic image and metabolite image acquired from brain tumor are demonstrated.

• Journal of the Korean Society of Radiology
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• v.8 no.5
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• pp.255-260
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• 2014

The acute lumbar pain patients who were unavoidable to take MRI examination were made to take altered lateral recumbent position. they were also not able to control their painfulness and to be in supine position. In this study, it is supposed to increase success rate of the MRI examination through taking the altered lateral recumbent position in using spine and body matrix coil. This altered position made relaxing lumber pain and fatigue for the patients who suffered from sever lumber pain. In these reasons, it decreases the motion artifacts through correcting uncomfortable posture. As a result, qualitative analysis for the image quality was estimated to have average points of supine position A group(lateral recumbent position) of normal candidates and B group(lateral recumbent position) of the abnormal candidates who have sever pain at 4.64, 3.44, and 3.40, respectively. In conclusion, while qualitative analysis in the examination with supine position of the normal patients had significantly high points, the qualitative analysis in the examination with lateral recumbent position of the normal patients and abnormal patients who had sever lumbar pain was almost same. In addition, it was judged that radiologists' imagery interpretation had no other problems in the image evaluation of B group who had acute lumbar pain of abnormal patients. Hereupon, if this technique becomes generalized for the patients who suffer from supine position in the examination, it is supposed to be useful in medical field.

• Journal of KIISE:Software and Applications
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• v.37 no.2
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• pp.110-119
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• 2010

In this paper, we propose an automatic segmentation of the prostate using intensity distribution and gradient information in MR images. First, active shape model using adaptive intensity profile and multi-resolution technique is used to extract the prostate surface. Second, hole elimination using geometric information is performed to prevent the hole from occurring by converging the surface shape to the local optima. Third, the surface shape with large anatomical variation is corrected by using 2D gradient information. In this case, the corrected surface shape is often represented as rugged shape which is generated by the limited number of vertices. Thus, it is reconstructed by using surface modelling and smoothing. To evaluate our method, we performed the visual inspection, accuracy measures and processing time. For accuracy evaluation, the average distance difference and the overlapping volume ratio between automatic segmentation and manual segmentation by two radiologists are calculated. Experimental results show that the average distance difference was 0.3${\pm}$0.21mm and the overlapping volume ratio was 96.31${\pm}$2.71%. The total processing time of twenty patient data was 16 seconds on average.

• Korean Chemical Engineering Research
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• v.48 no.1
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• pp.33-38
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• 2010

A microfluidic system has been developed using biomaterial for the measurement of cupric ion concentration. The cell-membrane-mimicking bilayer lipid membrane(BLM)-coated silver electrode was used for the sensing of cupric ion concentration. The silver-supported BLM could increase its stability. A silver-supported bilayer lipid membrane(s-BLM) was easily obtained using its self-assembling characteristics by immersing silver wire into lipid(phosphatidylcholine; PC) solution and then dipping into aqueous KCl solution. These s-BLMs were used to determine the relationship between $Cu^{2+}$ concentration and current crossing s-BLM. Their relationship showed high linearity and reproducibility. The calibration curve was constructed to express the relationship between $Cu^{2+}$ concentration and current in the $Cu^{2+}$ concentration range of 10 and $130{\mu}M$. This calibration curve was used to measure $Cu^{2+}$ concentration in an unknown sample. Microfluidic system with s-BLM was made of PDMS(polydimethyl siloxane) using typical soft photolithography and molding technique. This integrated system has various functions such as activation of the silver surface without cutting silver wire, coating of BLM on silver surface, injection of KCl buffer solution, injection of $Cu^{2+}$ sample and measurement of $Cu^{2+}$ concentration in the sample.

• Journal of the Korean earth science society
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• v.30 no.2
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• pp.153-164
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• 2009

We examined the regional 1-D deep resistivity structure of the Korean Peninsula using MT data acquired at seven sites located in the Kyongsang Basin and Kyonggi Massif. At the sites located in the Kyongsang Basin, surrounding sea distorts observed MT response and hence this distortion, so called "sea effect", is corrected using an iterative tensor stripping method. The 1-D layered inversion results for the seven MT sites reveal 4 layered structure, which is composed of 1) near surface layer, 2) upper crust, 3) lower crust and upper mantle, and 4) asthenosphere from the surface downward. Conrad interface, which is a boundary between upper and lower crust, is distinctly identified beneath all the MT sites. Conrad interface depth is estimated to about be 17km in the Kyongsang Basin and about 12km in the Kyonggi Massif, while the upper crust of the Kyongsang Basin is about 5 times more resistive than that of the Kyonggi Massif. Finally, asthenosphere is inferred to exist below a depth of approximately 100km with a resistivity of 200-300 ohm-m.

• Geophysics and Geophysical Exploration
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• v.7 no.2
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• pp.148-154
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• 2004

This article reviews the development of three-dimensional (3-D) magnetotelluric (MT) modeling. The 3-D modeling of electromagnetic fields is essential in understanding the physics of MT soundings, and in implementing an inversion method to reconstruct a 3-D resistivity image. Although various numerical schemes have been developed over the last two decades, practical methods have been quite limited. However, the recent rapid improvement in computer speed and memory, as well as the advance in iterative solution algorithms for a large system of equations, makes it possible to model the MT responses of complex 3-D structures, which have been very difficult to simulate before. The use of staggered grids in finite difference method has become popular, conserving a magnetic flux and an electric current and allowing for realistic discontinuous fields. The convergence of numerical solutions has been greatly accelerated by adopting Krylov subspace methods, proper preconditioning techniques, and static divergence corrections. The vector finite-element method using edge elements is also free from the discontinuity problem, and seems a natural choice for modeling complex structures including irregular topography because its flexibility allows one to capture full geometric complexity.

• Journal of Korea Water Resources Association
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• v.49 no.9
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• pp.761-771
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• 2016

The GloSea5 (Global Seasonal forecasting system version 5) is provided and operated by the KMA (Korea Meteorological Administration). GloSea5 provides Forecast (FCST) and Hindcast (HCST) data and its horizontal resolution is about 60km ($0.83^{\circ}{\times}0.56^{\circ}$) in the mid-latitudes. In order to use this data in watershed-scale water management, GloSea5 needs spatial-temporal downscaling. As such, statistical downscaling was used to correct for systematic biases of variables and to improve data reliability. HCST data is provided in ensemble format, and the highest statistical correlation ($R^2=0.60$, RMSE = 88.92, NSE = 0.57) of ensemble precipitation was reported for the Yongdam Dam watershed on the #6 grid. Additionally, the original GloSea5 (600.1 mm) showed the greatest difference (-26.5%) compared to observations (816.1 mm) during the summer flood season. However, downscaled GloSea5 was shown to have only a -3.1% error rate. Most of the underestimated results corresponded to precipitation levels during the flood season and the downscaled GloSea5 showed important results of restoration in precipitation levels. Per the analysis results of spatial autocorrelation using seasonal Moran's I, the spatial distribution was shown to be statistically significant. These results can improve the uncertainty of original GloSea5 and substantiate its spatial-temporal accuracy and validity. The spatial-temporal reproducibility assessment will play a very important role as basic data for watershed-scale water management.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2015.05a
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• pp.548-549
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• 2015

무인 잠수정은 자율 무인잠수정(이하 'AUV' 또는 '자율무인잠수정'을 혼용)과 원격조정잠수정(이하 'ROV'로 지칭)으로 분류를 할 수 있다. ROV는 테더 게이블로 인한 작업 범위의 한계와 운동성능 효율이 떨어지는 단점을 지니고 있어, 테더 케이블이 필요 없는 AUV에 대한 필요성이 증대되고 있다. 추측 항법 시스템인 관성 항법 시스템(inertial navigation system, 이하 'INS'로 지칭)은 외부 도움없이 관성측정 장치(inertial measurement unit, 이하 'IMU'로 지칭)를 활용하여 구성된 시스템을 말한다. IMU는 자이로 스코프(gyroscope), 가속도계(accelerometer), 지자기(magnetic)센서로 구성된 측정 장치로 3개의 센서를 사용하여 상호 보정을 통한 기동 체의 위치, 속도 및 자세 정보를 제공한다. 복합항법시스템은 추측항법시스템이 가지는 누적오차와 측위 항법시스템이 가지는 외부환경에 대한 단점을 상호 보완하는 방법으로 연구가 진행 중이다. 하지만 심해서 또는 해양의 특성에 따라 측위 시스템이 사용되지 못하기 때문에 추측 항법시스템의 다양한 관성 센서를 활용한 상로 보완과 신호처리 방법을 통한 연구 개발이 진행 중이다. 다양한 센서 정보를 통합하는 목적으로 칼만 필터와 같은 최적 필터기법이 보편적으로 사용되고 있다. 칼만 필터는 확률 선형 시스템에 대하여 공정잡음 및 측정 잡음이 가우시안 확률 분포를 따를 때 최적의 추정자가 된다. 또한 가우시안 조건을 만족하지 않는 경우에도 선형 추정자 중에 추정 오차의 분산이 가장 작은 추정자이다. 칼만 필터가 최상의 성능을 발휘 하려면 공정잡음과 측정 잡음의 실제 값을 정확히 알아내는 것이 중요하다. 잡음 수준에 대한 정보가 부정확 할 경우 칼만 필터는 발산 할 수 있기 때문에 시스템에서 잡음 수준의 공산은 칼만 필터의 최적 이득을 결정하는 중요한 요소로 추정치에 큰 영향을 준다. 따라서 칼만 필터를 추측항법시스템에 적용 시킬 경우 실제 모텔의 잡음 공분산을 정확히 추정할 수 있는 기법이 요구된다. 추측항법시스템은 다양한 센서를 활용하기 때문에 움직이는 기동 표적에 적용시 잡음공분상이 변하기 때문에 항법시스템이 저하 될 수 있다. 본 연구에서는 다양한 센서를 융합하여 해양 생체 로봇의 정밀 자세 제어가 가능한 시스템을 제안하고자 한다.

• Proceedings of the Korea Information Processing Society Conference
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• 2001.04b
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• pp.727-730
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• 2001

초고속 인터넷 서비스의 확대에 따라 이를 교육에 직 간접적으로 응용하기 위한 노력이 지속적으로 진행되어 왔다. 특히 웹 기반의 가상강의 저작도구를 통한 웹 코스웨어는 원거리 학습자들의 학습 욕구를 자기 주도적인 학습을 통해 가능케 했고 기존의 텍스트, 사운드를 통한 가상강의에서 동영상이 가미된 주문형 교육 서비스(EOD: Education On Demand)가 가능해졌다. 그러나 이를 이용하는 학습자는 전체적인 모듈의 이해를 통해 수업이 진행됨에 따라 학습과정에서는 질의응답을 튜터를 통해 웹 캐스팅이 이루어졌다. 따라서, 질의응답은 텍스트 형식의 E-mail, 채팅, 게시판, 방명록을 통해 이루어지므로 학습자가 요구한 질의 내용을 잘못 이해하고 튜터가 학습 과정에서의 피드백을 제공하지 못함으로써 개인 학습의 동기부여가 감소됨에 따라 흥미를 잃게 되었다. 본 논문에서는 이러한 문제점을 개선하기 위해 멀티 캐스팅 기법을 통해 교육용 서버를 이용한 학습지원도구를 분석, 설계한다. 가상강의는 기본적인 컨텐츠를 제시하고 그를 통해 수업이 진행되는 과정에서의 질의응답을 일대다(One-To-Many)의 멀티 캐스팅 서비스를 튜터가 지정한 교육용 서버를 통해 텍스트 형식이 아닌 강의자료로 쓰인 문서 파일에 직접 작성하여 전송하게 된다. 따라서 튜터는 메일링 서비스를 통해 질문사항을 자신의 폴더 서비스로 확인하고 즉시 학습자에게 피드백을 제공함으로써 튜터와 학습자들간의 커뮤니케이션이 활발히 이루어지며, 상호작용의 증가를 통해 웹 기반의 컨퍼런싱(WBC: Web Based Conferencing)을 가질 수 있게 된다.rver는 Client가 요청한 Content(services)를 전달 해 주는 컨텐트 전달 모듈(Content Deliver Module)과 서버 Phonebook 엑세스 모들(Server Phonebook Access Module)로 구성되어 있다.외 보다 높았다(I/O ratio 2.5). BTEX의 상대적 함량도 실내가 실외보다 높아 실내에도 발생원이 있음을 암시하고 있다. 자료 분석결과 유치원 실내의 벤젠은 실외로부터 유입되고 있었고, 톨루엔, 에틸벤젠, 크실렌은 실외뿐 아니라 실내에서도 발생하고 있었다. 정량한 8개 화합물 각각과 총 휘발성 유기화합물의 스피어만 상관계수는 벤젠을 제외하고는 모두 유의하였다. 이중 톨루엔과 크실렌은 총 휘발성 유기화합물과 좋은 상관성 (톨루엔 0.76, 크실렌, 0.87)을 나타내었다. 이 연구는 톨루엔과 크실렌이 총 휘발성 유기화합물의 좋은 지표를 사용될 있고, 톨루엔, 에틸벤젠, 크실렌 등 많은 휘발성 유기화합물의 발생원은 실외뿐 아니라 실내에도 있음을 나타내고 있다.>10)의 $[^{18}F]F_2$를 얻었다. 결론: $^{18}O(p,n)^{18}F$ 핵반응을 이용하여 친전자성 방사성동위원소 $[^{18}F]F_2$를 생산하였다. 표적 챔버는 알루미늄으로 제작하였으며 본 연구에서 연구된 $[^{18}F]F_2$가스는 친핵성 치환반응으로 방사성동위원소를 도입하기 어려운 다양한 방사성의 약품개발에 유용하게 이용될 수 있을 것이다.었으나 움직임 보정 후 영상을 이용하여 비교한 경우, 결합능 변화

• Geophysics and Geophysical Exploration
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• v.8 no.4
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• pp.270-279
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• 2005

Under the research project supported by Japanese Ministry of Education, Culture, Sports, Science and Technology (MEXT), we have conducted the development of GPR systems for landmine detection. Until 2005, we have finished development of two prototype GPR systems, namely ALIS (Advanced Landmine Imaging System) and SAR-GPR (Synthetic Aperture Radar-Ground Penetrating Radar). ALIS is a novel landmine detection sensor system combined with a metal detector and GPR. This is a hand-held equipment, which has a sensor position tracking system, and can visualize the sensor output in real time. In order to achieve the sensor tracking system, ALIS needs only one CCD camera attached on the sensor handle. The CCD image is superimposed with the GPR and metal detector signal, and the detection and identification of buried targets is quite easy and reliable. Field evaluation test of ALIS was conducted in December 2004 in Afghanistan, and we demonstrated that it can detect buried antipersonnel landmines, and can also discriminate metal fragments from landmines. SAR-GPR (Synthetic Aperture Radar-Ground Penetrating Radar) is a machine mounted sensor system composed of B GPR and a metal detector. The GPR employs an array antenna for advanced signal processing for better subsurface imaging. SAR-GPR combined with synthetic aperture radar algorithm, can suppress clutter and can image buried objects in strongly inhomogeneous material. SAR-GPR is a stepped frequency radar system, whose RF component is a newly developed compact vector network analyzers. The size of the system is 30cm x 30cm x 30 cm, composed from six Vivaldi antennas and three vector network analyzers. The weight of the system is 17 kg, and it can be mounted on a robotic arm on a small unmanned vehicle. The field test of this system was carried out in March 2005 in Japan.