• Title/Summary/Keyword: 자가 이식

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Preparation and Characterization of Small Intestinal Submucosa Coated with Poly(vinyl alcohol) for Wound Dressing (창상드레싱을 위한 Poly(vinyl alcohol)을 코팅한 소장점막하조직 시트의 제조와 특성 평가)

  • Lee Min-Suk;Yang Jea-Chan;Kim Soon-Hee;Song In-Bum;Kim Moon-Suk;Khang Gil-Son;Lee Hai-Bang
    • Polymer(Korea)
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    • v.30 no.3
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    • pp.259-265
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    • 2006
  • Small intestinal submucosa (SIS) consists of some growth factors which can stimulate cell activity, and PVA has been widely utilized in the area of wound dressing as hydrogel which is easy to be removed from wounds. In this study, native SIS sheets were coated with PVA by immersing them into 2, 4, and 10 wt% of PVA solution and then lyophilized on two type of molds to endow the prepared wound dressing with easy removal property from wounds. The mechanical properties were examined through tensile test. Moreover, enzymatic degradation, water uptake, and in vitro test were carried out to characterize the prepared SIS sheets. The tensile strength of the SIS sheets coated with PVA (PVA-SIS) were decreased, whereas the elongation were increased. Degradation ratio of the PVA-SIS sheets was decreased compare to native SIS. Water uptake ability was improved at 2 and 4 wt% of PVA. The degree of fibroblast attachment was lower than the native SIS sheets. In conclusion, this study suggests that the PVA coated SIS sheets have a potential for the applications of wound dressing and biodegradable injectable materials.

Bivenrticular Repair of Double Outlet Right Ventricle with Remote Ventricular Septil Defect. (비상관성 심실중격결손중을 동반한 양대혈관우심실기시증 환자에서의 양심실성 교정)

  • 방정현;이영탁
    • Journal of Chest Surgery
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    • v.30 no.7
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    • pp.641-646
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    • 1997
  • Understanding of the surgical anatomy of patients with double outlet right ventricle (DORV) is important in the planning of biventricular repair From May 1995 to September 1996, 7 patients underwent biventricular repair for DORV with remote ventricular septal defect. There were 5 males and 2 (tamales. Age at operation varied from 2 to 9 years(mean 3.4$\pm$ 2.7years). Preoperative diagnostic assessment was made by two-dimensional echocardiography and cardiac catheterization. Ventricular septal defect was perimembranous inlet type in all patients. Associated cardiac anomalies were pulmonary atresia in two, pulmonary stenosis in five and tricuspid chordal attachment to zonal septum in five. The operations were performed intraventricular repair and pulmonary enlargement in two, REV operation in two, and Rastelli operation in three. There was no early postoperative deaths and complications. The follow-up period war from 1 month to 18mon1hs, averaging 10: 6.1 months. In the past, we considered the Fontal operation indicative as primary choice when DORV was associated with abnormal tricuspid chordal attachment to the zonal septum, but now we believe that biventricular repair is feasible for those cases by making conal flap or reattachment method. Biventricular repair has theoretic advantages because it estabilishes normal anatomy and physiology, and it was concluded that the precise preoperative evaluation using both echocardiography and cardiac catheterization was essential to the successful surgery.

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Environmental Factors Related to Mass Moralities of Young Red Seabream (Pagrus major) in the Artificial Seed Production (일본산 참돔, Pagrus major 종묘생산과정중 사육수 변화로 인한 대량폐사)

  • 최상덕;정관식;김호진;김성수
    • Journal of Aquaculture
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    • v.11 no.2
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    • pp.203-212
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    • 1998
  • As seed production program is growing prosperously in various fishes in southern Korea, disease problems in larval and juvenile stages have emerged as a new research object. The following results were obtained from investigation about environmental factors related to mass mortalities of young Kinki red seabream, Pagrus major in process of artificial seedling production. Total length of red seabream larvae hatched was 2.93mm, and became 18.83~20.12mm at day 40. The first noticeable mortality of red seabream larvae (7.98~9.37mm) occurred in 25~30 day-old fish with the survival rates of 59.8~60.3%. Thereafter the mortality of larvae decreased, survival rate was 20.5~25.45% in day 40. After 20~30 days, the quality of pond water was bellow II class. During the experimental period COD, $PO_4$-P, $NO_2$-N, $NO_3$-N and $NH_$-N increased up to 3, 7, 34, 6 and 8 times, respectively, compared to initial ones. The number of viable bacteria in pond water and seabream larvae were $6.3{\times}10^6$~$2.3{\times}10^7$ cfu/ml, 4.3~$7.4{\times}10^6$ cfu/g in day 25, respectively. Among the isolated bacteria from the diseased red seabream in day 25, Vibrio spp. was considered to be the causative organism. External symptoms of this disease were floated, spined near the surface and inflated abdomen. When the isolated strain of the Vibrio was bathed to seabream larvae, $LD_50$ of seabream larvae was over $10^6$ cfu/ml of Vibrio spp.

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3.5 mm T-shaped LCP (Locking Compression Plate) Fixation for Unstable Distal Clavicular Fractures (3.5 mm T형 잠김 금속판을 이용한 원위 쇄골 골절의 치료 결과)

  • Lee, Churl-Woo;Kim, Hee-Chun;Roh, Jae-Young;Park, Young-Su
    • Clinics in Shoulder and Elbow
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    • v.11 no.1
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    • pp.41-45
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    • 2008
  • Purpose: To review the clinical and radiological results after an open reduction and internal fixation with a T-shaped LCP for unstable distal clavicle fractures. Materials and Methods: From February 2005 to June 2006, ten patients with distal clavicle Neer type II fractures were treated with an open reduction and internal fixation with a T-shaped LCP. Bony union was identified by plain radiography. The clinical results were analyzed according to the UCLA scoring system. Results: The mean time to fracture union was 9weeks and union was achieved in all cases. The mean UCLA score was 33.4 (30-35); excellent in 8 cases and good in 2 cases. In one case, loosening of one distal screw was occured and mild AC joint subluxation was observed in another case. Conclusion: 3.5 mm T-shaped LCP fixation is a useful technique for treating unstable distal clavicle fractures. This procedure provide stable fixation with no further AC joint injury.

IMMEDIATE RECONSTRUCTION WITH A.C.P AND ILIAC BONE GRAFT AFTER PARTIAL MANDIBULECTOMY ON RECURRENT AMELOBLASTOMA. (재발된 법랑아세포종 환자에서 하악골 부분절제술후 금속판과 자가장골을 이용한 즉시재건술에 대한 증례보고)

  • Moon, Haeng-Gyu;Yeo, Hwan-Ho;Kill, Beug-Dong;Kim, Woon-Gyu
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.11 no.2
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    • pp.53-59
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    • 1989
  • The ameloblastoma is the most common form of the odontogenic tumors exhibiting minimal inductive change in connective tissue, it comprising 1% of all tumor and cysts of the jaws. It is a true neoplasm, generally considered to be a benign but persistent or, locally malignant lesion. The tumor occurs most commonly in persons between the age of 20 and 50 years. 80% and 90% of all lesions are in the mandible. The presenting clinical signs and symptoms of the ameloblastoma very from patient to patient, but most common symptom was swelling, followed by pain, draining sinuses, and superficial ulcerations. It is slow-growing lesion, and the radiographic features of the ameloblastoma depend large one the nature and the local bone reaction to the particular tumor. Recurrence rate is about 33%, but this is probably due to incommplete initial removal of lesion. We had operated a patient ; 29-year-old female immediate reconstruction combined with autocompression plate and iliac bone graft and screw fixation after hemimandibulaectomy with recurred ameloblastoma involving from premolar to ascending ramus at right side mandible. We obtained favorable results of good function, short intermaxillary fixation periods and easy operation precedure than the other reconstruction methods.

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EFFECT OF PLATELET-RICH PLASMA ON AUTOGENOUS BONE GRAFT FOR BONE FORMATION IN RABBIT (가토 하악골 결손부의 자가골 이식시 혈소판 풍부혈장이 골형성 촉진에 미치는 영향에 관한 연구)

  • Jeon, Min-Su;Kim, Bo-Gyun;Song, Jun-Ho;Yeon, Byong-Moo;Lee, Young-Woo;Noh, Kyung-Lok;Kim, Da-Young;Pang, Ean-O;Kim, Jun-Hyun;Nam, Jeong-Hun;Gang, Tae-In;Lim, Sung-Chul;Park, Young-Ju
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.30 no.2
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    • pp.158-164
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    • 2008
  • Purpose : Recently, various materials were developed for enhancing bone formation capacity. Platelet rich plasma(PRP) is an autologous source with several growth factors and obtained by sequestering and concentrating platelets by gradient density centrifugation. This study was to evaluate the effect of PRP on healing of grafted bone. Materials and methods : Two blood samples were obtained and analysed for measuring platelet counts of normal blood and PRP. In experimental group, two defects of mandibular bone, 10mm in diameter and 4.0mm deep, were created in the mandible and immediately grafted with autogenous bone chips mixed with PRP. In control group, same bone defects were prepared and grafted with autogenous bone chips. Gelform was used for carrier of PRP. 2 weeks, 4 weeks, 8 weeks later, each group was evaluated with histologi-cal and histomorphometric analyses. Results : According to histological observation, experimental group was showed more anastomosing newly-formed woven bone having osteoblastic activation than control group. According to histomorphometric analysis, there were 9.11% more newly-formed bone volume in experimental group than control group at 2 weeks, 7.91% more at 4 weeks, 20.08% more at 8 weeks. Conclusion: Our results demonstrated PRP in autogenous bone graft could enhance the bone formation.

Study on the Low-temperature process of zinc oxide thin-film transistors with $SiN_x$/Polymer bilayer gate dielectrics ($SiN_x$/고분자 이중층 게이트 유전체를 가진 Zinc 산화물 박막 트랜지스터의 저온 공정에 관한 연구)

  • Lee, Ho-Won;Yang, Jin-Woo;Hyung, Gun-Woo;Park, Jae-Hoon;Koo, Ja-Ryong;Cho, Eou-Sik;Kwon, Sang-Jik;Kim, Woo-Young;Kim, Young-Kwan
    • Journal of the Korean Applied Science and Technology
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    • v.27 no.2
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    • pp.137-143
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    • 2010
  • Oxide semiconductors Thin-film transistors are an exemplified one owing to its excellent ambient stability and optical transparency. In particular zinc oxide (ZnO) has been reported because It has stability in air, a high electron mobility, transparency and low light sensitivity, compared to any other materials. For this reasons, ZnO TFTs have been studied actively. Furthermore, we expected that would be satisfy the demands of flexible display in new generation. In order to do that, ZnO TFTs must be fabricated that flexible substrate can sustain operating temperature. So, In this paper we have studied low-temperature process of zinc oxide(ZnO) thin-film transistors (TFTs) based on silicon nitride ($SiN_x$)/cross-linked poly-vinylphenol (C-PVP) as gate dielectric. TFTs based on oxide fabricated by Low-temperature process were similar to electrical characteristics in comparison to conventional TFTs. These results were in comparison to device with $SiN_x$/low-temperature C-PVP or $SiN_x$/conventional C-PVP. The ZnO TFTs fabricated by low-temperature process exhibited a field-effect mobility of $0.205\;cm^2/Vs$, a thresholdvoltage of 13.56 V and an on/off ratio of $5.73{\times}10^6$. As a result, We applied experimental for flexible PET substrate and showed that can be used to ZnO TFTs for flexible application.

Studies on Constituents of the Higher Fungi of Korea(XLVII) -Antitumor Constituents of the Cultured Mycelia of Agaricus campestris- (한국산(韓國産) 고등(高等) 균류(菌類)의 성분(成分) 연구(硏究)(제(第)47보(報)) -들버섯 배양(培養) 균사(菌絲)의 항암(抗癌) 성분(成分)-)

  • Park, Hee-Ju;Kim, Ha-Won;Woo, Myoung-Sik;Shim, Mi-Ja;Park, Wan-Hee;Choi, Eung-Chil;Kim, Byong-Kak
    • The Korean Journal of Mycology
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    • v.13 no.3
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    • pp.131-139
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    • 1985
  • To find antitumor constituents in the shake cultured mycelia of Agaricus campestris, the mycelia were extracted with hot water. Purification of the extract was carried out by ethanol precipitation and by ion exchange chromatography using DEAE-Sephadex A-50. Each fraction obtained during the purification procedure was examined for antitumor activity against sarcoma 180 in ICR mice. The antitumor fraction C was isolated. It showed 56.1% inhibition ratio at a dose of 20 mg/kg/day and consisted of a polysaccharide moiety (45%) and a protein moiety (18%). The polysaccharide was analyzed by G.L.C. and found to contain mannose (42.0%), glucose (25.5%), xylose (16.6%), fucose and galactose. The protein moiety was composed of 17 amino acids. The antitumor fraction A showed immunopotentiating activity by accumulating peritoneal macrophages and by increasing plaque-forming cells in mice.

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Design and Implementation of a Web-based Public Transportation Guidance System (웹기반 대중교통 안내시스템 설계 및 구현)

  • Bae, Su-Gang;Lee, Seung-Ryong;Choe, Dae-Sun;Jeong, Tae-Chung;Seung, Hyeon-U
    • Journal of KIISE:Computing Practices and Letters
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    • v.5 no.4
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    • pp.426-439
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    • 1999
  • 본 논문에서는 웹(World Wide Web)에서 사용자가 손쉽고 편리하게 이용할 수 있는 멀티미디어 대중교통 안내시스템 개발 경험을 소개한다. 개발된 시스템은 클라이언트와 서버 시스템, 경로탐색 시스템, 교통정보 저장 시스템, 노선 및 정류장 관리 시스템으로 구성되어 있다. 클라이언트에서 작동되는 사용자 인터페이스는 직관적으로 이해가 쉽고, 사용이 편리하며 인터액티브한 멀티미디어 대중 교통안내 서비스를 제공한다. 서버 시스템은 교통정보 수집 시스템으로부터 입력되는 데이타와, 경로탐색 시스템, 교통정보 저장 시스템과 연동되어 클라이언트의 요구사항을 처리하고 그 결과를 사용자에게 돌려준다. 수정된 A* 알고리즘을 이용하는 경로탐색 시스템은 최적경로를 탐색하며, 교통정보 저장 시스템은 현재 교통상황, 정류장, 노선, 지도 등의 정보를 저장한다. 노선 및 정류장 관리시스템은 시스템 관리자가 노선 또는 정류장 관리를 서버 화면의 지도상에서 효율적으로 수행할 수 있는 도구이다. 본 논문에서 다루는 대중교통 안내시스템은 Java로 구현하였기 때문에 확장과 이식이 용이하며, 시스템 유지보수 비용이 적게 드는 장점을 가지고 있다. 그리고, 웹 브라우저가 동작되는 환경에서는 어디서나 쉽게 접근이 가능하며 향후 구축될 Intelligent Transportation Systems(ITS)의 한 모듈로써 바로 작동될 수 있을 뿐만 아니라, 현재 인터넷상에서 제공되는 다양한 서비스와도 연동이 가능하다.Abstract This paper introduces our experience for developing a public transportation guidance system, which facilitates the World-Wide Web(WWW) to provide users with easier access and use. The proposed system is composed of four subsystems: client/server system, path search system, traffic data storage system, and traffic raw-data management system. The user interface in clients utilizes Java to furnish users with multimedia data accessibility and interactivity. The server processes clients' requests based on the traffic data coming from remote sensing devices and interacts with the path search system and traffic data storage system to provide users with the results. The path search system, which uses a modified A* algorithm, produces optimal solutions based on dynamic traffic data. The traffic data storage system stores the current traffic information together with the geographical information about the b$us_way routes. The traffic raw-data management system is a graphical user interface which enables the system manager to handle the traffic information easily on the map in the terminal screen. The system has considerable benefits such as portability, scalability, and flexibility since it is implemented using Java. Also, it can be extended to an integrated Intelligent Transportation Systems(ITS) which includes a variety of information on the Internet as well as traffic information.n.

Seed Production and Cultivation of Ecklonia stolonifera Okamura, Phaeophyta (갈조 곰피(Ecklonia stolonifera Okamura)의 종묘생산과 양성)

  • Kim, Dong-Sam;Hong, Jung-Pyo;Kim, Young-Dae;Song, Hong-In;Kim, Hyung-Geun
    • Journal of Aquaculture
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    • v.20 no.1
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    • pp.7-13
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    • 2007
  • The seed production of Ecklonia stolonifera Okamura was studied under laboratory conditions through the embryonic sporophyte stage and the field cultivation was conducted in eastern coast of Korea. The germination of zoospores occurred within 3 days and the growth of gametophytes was most rapid at $25^{\circ}C$ and $20\;{\mu}mol{\cdot}m^{-2}s^{-1}$. Sporophyte growth was highest at $20^{\circ}C$ and $20\;{\mu}mol{\cdot}m^{-2}s^{-1}$ and lowest at $25^{\circ}C$ and $80\;{\mu}mol{\cdot}m^{-2}s^{-1}$. In the nursery culture of E. stolonifera lasting for 2 weeks in January, the initial blade length of E. stolonifera (about $500\;{\mu}m$) grew to $526.3{\pm}176.0\;{\mu}m$ at water temperature of $12.05^{\circ}C$. The blade length and width reached their maxima in July, after which the ends of blade and stem began to degrade with the increase in water temperature. The degraded end of the blade started to regenerate in October, when water temperature began to decline. This species can be considered a potential candidate for aquaculture, increasing in the availability of raw material and aiding in recovery of seaweed bed.