• Title/Summary/Keyword: 자가 이식

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Reconstruction of Bone Defects Caused by Tumor Resection Using Recycled Autograft Augmented with VFG (재생 자가골과 생비골 이식술을 이용한 종양절제 후 골 결손의 재건)

  • Chung, Yang-Guk;Kang, Yong-Koo;Bark, Won-Jong;Rhee, Seung-Koo;Lee, An-Hi;Park, Jeong-Mi;Park, Bo-Youn
    • The Journal of the Korean bone and joint tumor society
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    • v.15 no.2
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    • pp.93-103
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    • 2009
  • Purpose: We evaluated the outcomes of surgical reconstructions using recycled autograft augmented with VFG for bone defects caused by tumor resections. Materials and Methods: Ten patients with a malignant or locally aggressive bone tumor who were managed with recycled autograft augmented with VFG and followed up minimum 1 year were evaluated for bone union, functional result and complications. The influence of various factors on bone union and functional outcomes were also analyzed. Results: Bone unions were obtained at 13 of 20 junctions. Average union time was 3.7 months at metaphyseal junctions and 8 months at diaphyseal junctions (P<0.05). At diaphyseal junctions, younger aged group and intramedullary location group showed earlier bone union (P<0.05). The mean functional score was 81%. There were 3 nonunions, 4 delayed unions and 2 recycled bone resorption combined with fractures. Conclusion: To obtain excellent results, proper microvascular technique, sufficient length of VFG bridging both junctions, stable internal fixation and protection of reconstructed bone until union are necessary.

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체외배양조건이 체세포 핵이식란의 배발달 및 배반포의 동결-융해 후 생존성에 미치는 영향

  • 최은주;이호준;연승은;윤종택
    • Proceedings of the KSAR Conference
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    • 2002.06a
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    • pp.43-43
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    • 2002
  • 체세포 핵이식에 의한 산자가 양, 소, 염소, 쥐 및 최근에 돼지에서 보고되었지만, 생산된 배반포의 동결보존에 관한 연구결과는 보고되지 않고 있다. 따라서, 본 연구는 체세포 핵이식란의 활용과 산업화 촉진을 위해서 체세포 핵이식 유래 배반포의 동결성 향상에 배양조건이 미치는 영향을 조사하고자 실시하였다. 공여세포는 60일령의 태아세포를 10% FBS 가 첨가된 DMEM 에서 39℃, 5% CO₂의 incubator에서 배양하여 monolayer confluent 형성을 유도한 후 0.25%trypsin 처리하였다. (중략)

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Reconstruction of the Glenoid Using Iliac Bone Graft for Recurrent Anterior Shoulder Instability with Severe Glenoid Bone Defect - A Report of Two Cases - (관절와의 심한 골결손을 동반한 견관절 전방 불안정성에서 장골 이식술을 이용한 관절와 재건술 - 2예 보고 -)

  • Lee, Seong-Man;Jung, Won-Ju;Lee, Hyun-Joo;Jeon, In-Ho
    • Clinics in Shoulder and Elbow
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    • v.13 no.1
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    • pp.117-122
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    • 2010
  • Purpose: The purpose of this report was to assess a surgical technique-using an autogenous tricortical iliac crest bone graft in patients with epilepsy-for anatomical glenoid reconstruction for recurrent anterior glenohumeral instability with severe glenoid deficiency. Materials and Methods: We studied two cases of recurrent anterior dislocation of the shoulder due to epilepsy. These cases were treated with anatomical glenoid reconstruction using an autogenous tricortical iliac crest bone graft. Results: Both cases achieved bone union in 5 months. There was no recurrence of instability and pain. Both cases had normal range of motion. Conclusion: Anatomical glenoid reconstruction for recurrent anterior glenohumeral instability with severe glenoid deficiency using an autogenous tricortical iliac crest bone graft is a successful surgical technique for achieving shoulder stability.

Comparison of Quality of Life of Autologous and Allogeneic Hematopoietic Stem Cell Transplantation Recipients (자가 조혈모세포 이식환자와 동종 조혈모세포 이식환자의 삶의 질의 비교)

  • Kim, Eun-Ji
    • Asian Oncology Nursing
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    • v.8 no.1
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    • pp.50-60
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    • 2008
  • Purpose: The purpose of this study was to compare Quality of life (QOL) in type and time after Hematopoietic stem cell tansplantation (HSCT) for patients with hematologic cancer. Method: This study was cross-sectional. The autologous recipients was 120, the allogeneic recipients was 237. The obtained data were analyzed using T-test, One-way ANOVA, Scheffe's test. Results: No significant differences were total QOL between the autologous and allogeneic recipients. But the autologous recipients reported better status than the allogeneic recipients in physical domain, especially 1-3 yr after HSCT. There was poorer QOL of 1-3 yr compared to 1 yr after HSCT in physical, psychological and social domain between the two groups. QOL in time after HSCT of the autologous recipients was significance differences in psychological, social domain. And QOL in time after HSCT of the allogeneic recipients was significant differences in physical, psychological and social domain. Conclusions: QOL of recipients undergoing HSCT is recovered beyond 3 yr point. Accordingly, long term care and service is essential to recipients undergoing HSCT. And further studies with a longitudinal design are necessary.

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Autogenous Transplantation of Third Molar to Replace Hopeless Tooth (예후 불량한 치아를 대체하는 제3대구치를 이용한 자가치아이식술)

  • Song, Il-Seok
    • Journal of the Korean Academy of Esthetic Dentistry
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    • v.29 no.1
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    • pp.13-24
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    • 2020
  • Autotransplantation is the surgical repositioning of an autogenous erupted or unerupted tooth from one site to another in the same individual. This treatment is indicated in traumatic tooth loss, teeth with severe caries, congenitally missing teeth, teeth with bad prognosis and in case of developmental anomalies of teeth. The following 2 cases describe the potential to utilize autotransplantation to replace hopeless teeth with sound wisdom teeth.

The Use of Greater Saphenous Vein In Situ Graft in Arterial Occlusive Disease of Lower Extremity (하지동맥 폐쇄성 질환에서 자가 대복재정맥 정위 이식편의 이용)

  • Shin Yong-Chul;Kim Mi-Jung;Song Chang-Min;Ahn Jae-Bum;Kim In-Sub;Kim Woo-Sik;Kim Byung-Yul
    • Journal of Chest Surgery
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    • v.39 no.6 s.263
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    • pp.456-461
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    • 2006
  • Background: Distal anastomosis using artificial vascular graft is difficult when luminal size mismatch occurred owing to severe occlusion of popliteal artery and its branches. So we reconstructed blood flow to ischemic lower limb by using autologous greater saphenous vein in situ graft (GSVISG) as vascular graft material. Material and Method: From July 2000 to July 2005, 26 patients treated using GSVISG. We analyzed clinical results retrospectively by chart review. Result: There was no in hospital or early postoperative death and 6 late deaths occurred during follow up period. Postoperative complications were 5 cases of early graft obstruction, 2 cases of wound dehiscence, 1 case of graft aneurysmal change, 1 case of seroma formation at inguinal wound and 1 case of graft injury during valvulotomy. Overall patency rate during follow up period was 69.3%. Conclusion: Greater saphenous vein in situ graft is acceptable vascular graft for arterial occlusive disease of lower extremity.

Left Ventricular Remodeling in Pediatric Orthotopic Size Mismatched Heart Transplantation (몸무게 차이가 큰 성인 공여자-소아 수용자간 심장이식에서의 좌심실 재형성)

  • Lee Seung-Cheol;Yoon Tae-Jin;Kim Young-Hwee;Park In-Sook;Kim Jong-Wook;Seo Dong-Man
    • Journal of Chest Surgery
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    • v.39 no.3 s.260
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    • pp.226-229
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    • 2006
  • Recently, heart transplantation has been accepted as a standard treatment for infant and children with end-stage cardiomyopathy or complex congenital heart disease. Due to the shortage of donors, size-mismatched cardiac transplantation is common. After size-mismatched transplantation, there could be side-effects such as hypertension and hypertensive encephalopathy because of the big-heart. Donor heart is also known to do remodel as time goes by. This is a case report of a size-mismatched heart transplantation between 9-year-old boy and a 39-year-old female whose body weight is almost twice of him. In this case, classical postoperative hypertension and hypertensive encephalopathy developed but was successfully managed. The donor heart has remodeled to normal dimension during 3 years follow-up period.

Allogeneic Hematopoietic Stem Cell Transplantation in Juvenile Myelomonocytic Leukemia (연소형 골수단구성 백혈병에서의 동종 조혈 모세포 이식)

  • Yoo, Keon Hee;You, Dong Kil;Lee, Soo Hyun;Sung, Ki Woong;Cho, Eun Joo;Koo, Hong Hoe
    • Clinical and Experimental Pediatrics
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    • v.48 no.2
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    • pp.178-185
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    • 2005
  • Purpose : The purpose of this study was to evaluate the outcome of children with juvenile myelomonocytic leukemia(JMML) treated with allogeneic hematopoietic stem cell transplantation(allo-HSCT). Methods : Eleven JMML patients aged 8-39 months underwent allo-HSCT. The sources of grafts were unrelated donors(n=7), HLA-matched siblings(n=3) and an HLA 1-antigen mismatched familial donor. All patients had received chemotherapy ${\pm}13$-cis-retinoic acid(CRA) before transplant, and CRA was used, posttransplant, in six patients. Results : Only three patients were in complete remission(CR) at the time of transplantation. Initial chimeric status revealed complete donor chimerism(CC) in five patients, mixed chimerism(MC) in five and autologous recovery(AR) in one. One patient with MC having persistent splenomegaly eventually turned to CC and CR after rapid tapering of cyclosporine, combined with daily use of CRA. An AR case relapsed shortly after transplant but was rescued with second, unrelated cord blood transplantation. Ultimately, six patients are alive, event-free, with a median follow-up of 15.5 months posttransplant. All three deaths occurred in patients who failed to achieve CC, leading to disease progression. Conclusion : We suggest that graft-versus-leukemia effect play an important role and CRA a possible role in posttransplant leukemic involution in JMML. In patients whose leukemic burden is still high with MC after transplant, early tapering of immunosuppressants and introduction of CRA might provide a chance of a cure for some patients.