• Journal of the Korean Society of Radiology
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• v.12 no.4
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• pp.443-450
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• 2018

The Geant 4 simulated the linear accelerator (VARIAN CLINAC) based on the previously implemented BEAMnrC data, using the head structure of the linear accelerator. In the 10 MV photon flux, Geant4 was compared with the measured value of the percentage of the deep dose and the lateral dose of the water phantom. In order to apply the dose calculation to the body part, the actual patient's lung area was scanned at 5 mm intervals. Geant4 dose distributions were obtained by irradiating 10 MV photons at the irradiation field ($5{\times}5cm^2$) and SAD 100 cm of the water phantom. This result is difficult to measure the dose absorbed in the actual lung of the patient so the doses by the treatment planning system were compared. The deep dose curve measured by water phantom and the deep dose curve calculated by Geant4 were well within ${\pm}3%$ of most depths except the build-up area. However, at the 5 cm and 20 cm sites, 2.95% and 2.87% were somewhat higher in the calculation of the dose using Geant4. These two points were confirmed by the geometry file of Genat4, and it was found that the dose was increased because thoracic spine and sternum were located. In cone beam CT, the dose distribution error of the lungs was similar within 3%. Therefore, if the contour map of the dose can be directly expressed in the DICOM file when calculating the dose using Geant4, the clinical application of Geant4 will be used variously.

• The Korean Journal of Cytopathology
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• v.7 no.1
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• pp.1-11
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• 1996

From the concepts of cellular pathology and of exfoliative cytology, as elucidated by Virchow and Papanicolaou respectively in the late 19th and early 20th century, have evolved the primary methods for the diagnosis of cancer today. From Papanicolaou's concept of exfoliative cytology developed fine needle aspiration biopsy in the early 1960's, this has become a major diagnostic procedure and has contributed to a significant reduction in open biopsies and, therefore, to medical cost-effectiveness immunobiochemical techniques provided us with a supplement to cancer diagnosis in the 1980's. The immunoperoxidase method, using monoclonal antibodies, is applied primarily as an ancillary measure to elucidate the nature of cancers The availability of specific monoclonal antibodies has greatly facilitated the identification of cell products or surface markers. For example, antibodies directed against intermediate filaments have proved to be of value in determining the histogenesis oi poorly differentiated neoplasms. Tumor markers may serve as biochemical indicators of the presence of a neoplasm. They can be detected In plasma and other body fluids. Their concentration can be applied as a diagnostic test, for monitoring the clinical course of known cancer, and as a screening measure to detect certain cancers in a population at risk. Flow cytometry is a useful tool for distinguishing several cell characteristics, such as the immunophenotype of leukemia-lymphoma cells, the DNA content of neoplastic cells, and cell proliferation rate. Molecular biologic techniques provided a giant step for the management of cancer patients encompassing diagnosis, prognostic evaluation, and therapy. Nucleic acid hybridization techniques are utilized as Southern, Northern, and dot blots and in situ hybridization. Molecular biology and its techniques may bring a blight new horizon for understanding cancer biology and in designing therapy on the basis of gene manipulation.

• Clinics in Shoulder and Elbow
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• v.15 no.2
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• pp.65-72
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• 2012

Purpose: To evaluate the differentiation potential of stem cells and their immunophenotype from 3 different sources. Methods: Our study involved three stem cell sources-subacromial bursal tissue, bone marrow, and umbilical cord blood. We obtained the subacromial bursal tissue and bone marrow from the patients undergoing shoulder surgery. After collecting the sample, we applied specific induction media for neurogenic, adipogenic and osteogenic differentiation. Also, flow-cytometry analysis was done to reveal the cell surface antigens. Results: We obtained 100% (8 cases) neural and adipogenic differentiation, but 62.5% (5 of 8 cases) osseous differentiation among the subacromial bursal tissue group. Bone marrow derived cells showed 100% neural (6 cases) and adipogenic (5 cases) differentiation, but 80% (4 of 5 cases) osseous differentiation. Umbilical cord blood derived cells revealed 97% (65 of 67 cases) neural, 53.7% (29 of 54 cases) adipogenic and 68.4% (39 of 57 cases) osseous differentiation. Immunophenotype analysis revealed that surface markers of bone marrow, subacromial bursal cell and umbilical cord blood derived mesenchymal stem cells are different from each other. Conclusions: Mesenchymal stem cells are potential agents in regenerative medicine and are characterized by expression of surface markers and by their differentiation potential. Our study with stem cells from subacromial bursal tissue, bone marrow and umbilical cord discovered that each stem cell has unique differentiation potential and function based on its origin. Various stem cells show multi-lineage differentiations in vitro which can be correlated to in vivo conditions.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.2
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• pp.388-395
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• 2020

This study was conducted from March 15 to March 19, 2019. The purpose of this study was to examine the recognition of uniforms and their images for the selection and development of uniforms and the pursuit of images for dental hygienists and students in some regions. Study methods included frequency analysis, factor analysis, reliability analysis, ANOVA, chi-squared test, and regression analysis. The collected data was analyzed using the IBM SPSS Statistics 21.0 program. This study found that students majoring in dental hygiene thought that uniforms influenced their image and that they influenced the image of the hospital. In addition, students who experienced clinical practice preferred the pants type to the uniform type and the color to achromatic color. In addition, these students preferred scrubs and the use of Crocs for shoes. The results of this study showed that dental hygiene students considered image transmission through uniforms as important. However, it appears that they prefer practical uniforms and shoes over uniforms that convey external images. This is a part that makes us aware of the need for changes in training clothes and training. In conclusion, it is necessary to develop a practical uniform while expressing the image of the institution, which will be reflected in future dental uniform selection.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.8
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• pp.154-159
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• 2020

In this study, we set the occupational satisfaction and communication ability of clinical dental hygienists as the main variables, and investigated the factors that affect communication within the organization to improve the work of dental hygienists. Self-reporting questionnaires were administered to 200 dental hygienists working in dental hospitals and dental clinics in Seoul and Gyeonggi Province from May 18, 2019 to June 12, 2019. We analyzed the data with Pearson correlation analysis and multiple regression analysis. The significance level was set at 0.05. Research results: Job satisfaction (r=0.193, p<0.05) and communication ability (r=0.404, p<.001) showed a significant positive correlation with intra-organizational communication, and individual communication ability (β=0.461, P<.001), which was found to have a significant effect on communication within this organization. Therefore, in order to improve the communication skills of dental hygienists, they should be proud of their work as professionals, enhance their job satisfaction, and be able to have a clear expression of their own intentions and effective dialogue. Efforts should be made to provide opportunities such as opening related lectures during internal education and maintenance education.

• Korean Journal of Human Ecology
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• v.10 no.2
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• pp.189-203
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• 2001

The pulpous of this study is to investigated the kind and feature of the knots used in four categories, "living, clothing, ceremony, and decoration", after analysing and examining 42 knot remains of the folklore museum of On yang. The method were by old books and various kind's related books, history of knots and kind of knots investigated and analyze relics were actual proof investigation of real things and supplementary materials were photos, drawings, and museum's explanation used. The results are as is following ; First, a knot is twisted by two threads, formed in the process of twisting, become in equal shape, and made in symmetry. Second, In knot's names, there are sangkang, karakge, ankyongchip, jamjary, kukhwa, bol, byongary, memi, kkondiki, kong, yonbong which are easily seen in nature. Third, a knot was used in as living things in the era of the three Kingdoms, as a decoration such as Buddhism goods in Koryo. In the era of Cho sun, Because of the development of knot's kind and the variety of service, it was the target of restriction as a luxury. Fourth, as a result of investigating museum's relics, a knot was smaller than the chief object because that is a decoration. Fifth, there are 8 kinds for living and clothing which are simple knots "doramaetup, karakgemaetup, and sangtchokmaetup". Sixth, the complex knots such as kukhwamaetup, byongarymaetup, and 3bolkamkae emaetup are used on pangchang, chokja, nambawi, and chobawi. Seventh, there are 10 kinds for ceremony, the simple knots are twisted and the complex knots such as kukhwamaetp, maehwamaetup, nabimaetup, and sasaekgupoki are used. Eighth, there are 14 kinds for decoration, the simple knots such as doraemaetup, kakagemaetup, santchokmaetup, and ankyongchipmaetup and the applied knots such as kukhwamaetup, byongarymaemaetup, changkumaetup, nabimaetup, and seokssima etup are used. There are 42 knot remains in the folklore museum of On yang. Of them, there are 33 kinds in the present, 17 used. that is because only several knots have been used. Finally, to forget the knot's way, we will set up a plan to keep with it.

• Tuberculosis and Respiratory Diseases
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• v.59 no.3
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• pp.266-271
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• 2005

Background : Ethambutol(EMB) is one of the first-line drugs included in short-course anti-tuberculosis therapy. The point mutations in embB gene have been speculated to be associated EMB resistance. However, detection of embB mutations at these positions have been observed in both EMB-susceptible isolates; thus, it remains controversial whether these mutations are associated with EMB resistance Methods : The 36 M. tuberculosis isolates were selected from clinical isolates which tested susceptible to EMB and resistant to at least one drug. DNA extracted from the isolates was analyzed by amplifying embB gene. The PCR products were purified and directly sequenced. We reviewed the history of past drug susceptibility test results. Results : Out of 36 EMB-susceptible strains, 3 strains (8.3%) had a mutation in codon 306 or 406 of the embB gene. These three strains had at least isoniazid resistance. They grew at 1.0 mcg/ml of EMB in Lowenstein-Jensen media. The patients of the strains were continuously smear-positive for over 3 years despite taking TB therapy. One strain had been EMB-resistant in past drug susceptibility tests. Conclusion : EMB-susceptible strains containing embB mutation may be caused by decreased viability in vitro test not by itself.

• Journal of dental hygiene science
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• v.7 no.2
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• pp.89-96
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• 2007

The purpose of this study was to examine the relationship between the self-expression level of dental hygiene students related to communicative competence and their stress during clinical practice and what affected their stress. The subjects in this study were 125 dental hygiene students in W college, on whom a survey was conducted from September 18 through 30, 2006. After the collected data were analyzed with SPSS WIN 10.0 program, the following findings were acquired: 1. When a factor analysis was made to evaluate the self-expression of the students, there appeared three different categories of self-expression: voice/content, facial expression/attitude and sentiment. The three made a 58.1% prediction of their self-expression. As for overall reliability, they turned out highly reliable(Cronbach'a = .881). 2. The dental hygiene students got a mean of 3.58 out of possible five points in self-expression, which indicated that they expressed themselves relatively well. Concerning connections between their general characteristics and self-expression level, those who were inactive during clinical practice got a mean of 3.28, whereas the others who were active got a mean of 3.85. It implied that those who took a more active attitude to clinical practice expressed themselves better(p < .01). The person with whom they found it hard to get along made a statistically significant difference to their self-expression(p < .05). The students who didn't fare well with dental hygienists got the best score(3.70). The second best group(3.53) didn't get along with dentists, followed by assistant nurses(3.46) and patients/caregivers(3.31). As for the impact of the field of dream job, the students who hoped to work or study overseas(4.21) excelled in self-expression those who wanted to be hired in a general hospital, to go onto a school of higher grade and to work in a public dental clinic(p < .05). Among the general characteristics, satisfaction level with major, health status and motivation of choosing dental hygiene made no statistically significant differences to their self-expression. 3. Regarding relations between self-expression level and stress about clinical practice, those who didn't express themselves properly in terms of sentiment scored higher in stress level(3.65). Their stress was statistically significantly different according to self-expression level (p < .05). 4. As for the influence of self-expression and general characteristics on stress with clinical practice, sentiment was selected from among the self-expression categories as a decisive factor to affect stress. Their stress varied statistically significantly with that(p < .05). In contrast, their demographic variables made no statistically significant difference to that, which made a 79.2% prediction of it.

• Journal of Digital Convergence
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• v.16 no.2
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• pp.431-440
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• 2018

This study examined the effectiveness of the cognitive activity integration program to delay the progression of the mild demented elderly. The subjects were divided into experimental group and comparative group for 12 cases of mild dementia, and the cognitive activity integration program was conducted for 8 weeks and compared with the MMSE-K, ADL & IADL, CDR and GDS scales. The results show that the effectiveness and continuity of the program are as follows. First, as an implication of practical dimension, integrated program of fusion and complexity is more effective than cognitive activity program of single domain. Second, the cognitive activity integration program must be continuously provided to maintain its effectiveness. Third, the cognitive activity integration program is as important as the practice process. It is necessary to develop and disseminate a cognitive activity integration program that reflects fusion and complex treatment techniques applicable to the elderly with mild dementia by practical suggestion. Policy suggestions are needed to continue the ongoing cognitive activity integration program, to maintain effectiveness, and to delay the progress of dementia.

• The Korean Journal of Cytopathology
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• v.10 no.2
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• pp.121-126
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• 1999

The usefulness of E-cadherin immunostaining as a marker of malignancy in the body fluids was investigated in the present study. Thirty-three histologically proven cases of cell blocks from the pleural, peritoneal, and pericardial fluids were studied by immunocytochemistry for E-cadherin antibody using LSAB method. These cases were cytologically diagnosed as adenocarcinoma (25 cases) and atypical cells (8 cases). Tumor cells showed strong positive membranous staining for E-cadherin antibody in 21 out of 25 cases (84%) of adenocarcinoma. E-cadherin staining was not found in 6 of 8 cases of suspicious maligancy. The sensitivity and specificity were 84% and 75%, respectively. Reactive mesothelial cells and Inflammatory cells scattered were all negative. In conclusion, E-cadherin is an useful adjunctive marker to distinguish reactive mesothelial cells from the carcinoma cells in the body fluids.