• 제목/요약/키워드: 임상 지수

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Acupuncture, an Adjunct Therapy for Asthma: a Pilot Study Protocol of Randomized Controlled Trial (본 임상시험을 대비한 천식 침치료 무작위 대조군 예비 임상시험 프로토콜)

  • Choi, Jun-Yong;Oh, Dal-Seok;Roh, Young-Lae;Jung, Hee-Jae;Jung, Sung-Ki;Choi, Sun-Mi
    • Korean Journal of Acupuncture
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    • v.25 no.3
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    • pp.43-51
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    • 2008
  • 배경 : 최근까지 이루어진 천식의 침치료 무작위 대조군 연구들에 의한 결과는 뚜렷한 효과를 보여주지 못하고 있다. 이러한 요인의 하나로 적절한 피험자 수를 정하기 위한 예비 임상시험의 부재가 거론되고 있다. 따라서 천식에 대한 침치료의 본 임상시험에 앞서 이의 실행 가능성 및 규모를 예측하는 예비임상시험이 필요한 상황이다. 목적 : 예비임상시험을 통해 서양의학적 치료를 받고 있는 천식환자들에 대한 침치료의 부가적 효과를 검증하기 위한 본 임상시험의 실현 가능성을 예측하기 위함. 방법 : 본 시험은 무작위 단일 맹검 대조군 평행 설계 예비 임상시험이다. 1차 평가변수는 최대 호기량 검사기로 집에서 아침, 저녁으로 매일 측정한 수치로 구해진 최대 호기 유속 일중 변동률의 1주간 평균치 변화이며 2차 평가변수는 의료기관에서 시행하는 폐기능 검사, 기준시점 호흡곤란 지수, 호흡곤란 변화에 대한 지수, 천식환자들의 삶의 질 평가를 위한 설문 등이다. 피험자 수는 총 45명으로 선정 및 제외기준을 통해서 참여하게 되며 1주간의 최대 호기 유속 기저치 평가 기간을 거친 후 진짜침 처치 군, 가짜침 처치 군, 대기군 세 군에 각각 무작위로 15명씩 할당된다. 모든 피험자에게 기존의 천식관련 약물의 사용을 허용하며, 진짜침 처치군 및 가짜침 처치군은 주 3회 4주간 해당 처치를 받고 2주 후에 각 평가 항목에 대하여 추적, 관찰하게 된다. 대기군은 기존의 천식관리를 유지하면서 2주마다 방문하여 총 6주간 평가를 받고 진짜침 처치를 4주간 받게 된다. 고찰 : 본 연구는 국내에서 최초로 이루어지는 천식에 대한 침 무작위 대조군 예비 임상시험으로 향후 적절한 피험자 수와 실행가능성을 예측할 수 있으리라 기대된다.

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Usefulness of Triglyceride and Glucose Index to Predict the Risk of Hyperuricemia in Korean Adults (한국 성인에서 고요산혈증 위험을 예측하기 위한 중성지방-혈당 지수의 유용성)

  • Shin, Kyung-A;Kim, Eun Jae
    • Journal of the Korea Convergence Society
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    • v.11 no.12
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    • pp.283-290
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    • 2020
  • The purpose of this study was to evaluate the usefulness of the triglyceride and glucose(TyG) index to predict the risk of hyperuricemia in Korean adults. This study included 14,266 men and 9,033 women over 20 years old who underwent health screenings from 2017 to 2019 at a general hospital in Seoul. To confirm the risk of hyperuricemia and predictive ability of the TyG index, logistic regression analysis and ROC curves were obtained. The accuracy of the TyG index for predicting hyperuricemia was 0.68, 0.61 for men and 0.67 for women(respectively p<0.001). The risk of hyperuricemia in the TyG index was 1.69 times higher in the fourth quartile than in the first quartile, 2.03 times higher in men and 2.07 times higher in women(respectively p<0.05). Thus the TyG index was not of high diagnostic usefulness as a screening test for hyperuricemia, but it was related to the TyG index and hyperuricemia.

The novel expression method of pediatric body composition : fat mass index and fat-free mass index (소아 체성분의 새로운 표현법: 체지방량지수(fat mass index)와 제지방량지수(fat-free mass index))

  • Cho, Young Gyu;Kang, Jae Heon;Song, Hye Ryoung;Kim, Kyung A;Song, Ji Hyun;Jung, Myeong Ho
    • Clinical and Experimental Pediatrics
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    • v.50 no.7
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    • pp.629-635
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    • 2007
  • Purpose : This study was conducted to assess the usefulness of fat-free mass index (FFMI) and fat mass index (FMI) as novel expression methods of body composition in children. Methods : A total of 466 Second grade students-248 boys and 218 girls- from all elementary schools the Gwacheon City underwent anthropometric measures including bioelectrical impedance analysis (BIA) and biochemical tests. The correlation coefficients between obesity indices, including FMI and FFMI, and metabolic risk factors, were assessed. Metabolic risk factors of children with increased FMI were compared with those of children with normal FMI. We compared FMI and FFMI percentile distribution between this study's subjects and the subjects of the Fukuoka body composition study. Results : FMI was lower and FFMI was higher in this study's subjects compared to the subjects of the Fukuoka body composition study. FMI was correlated with other obesity indices and several metabolic risk factors. Metabolic risk was higher in children with increased FMI than in children with normal FMI. Conclusion : FMI and FFMI were useful indicators in comparing difference of body composition among children that had different body size and growth. High FMI was related to increase of metabolic risk in children.

A CLINICAL EVALUATION OF SAFETY OF AN OFFICE BLEACHING GEL CONTAINING 30% HYDROGEN PEROXIDE (30% 과산화수소를 함유한 전문가 미백제의 안전성 평가)

  • Kim, Sin-Young;Park, Je-Uk;Kim, Chang-Hyen;Yang, Sung-Eun
    • Restorative Dentistry and Endodontics
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    • v.35 no.3
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    • pp.198-210
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    • 2010
  • This study evaluated the safety of an office bleaching gel (RemeWhite, Remedent Inc., Deurle, Belgium) containing 30% hydrogen peroxide. 37 volunteers were received office bleaching with the RemeWhite for 3 times at one visit, total 2 visits. As control group, the same gel in which hydrogen peroxide was not included was applied to 34 volunteers with the same protocol. There was no difference between experimental group and control group using electric pulp test. In the result of gingival inflammation index and tooth sensitivity test, there was mild pain response in experimental group but it disappeared as time went by. Therefore, safety of the office bleaching gel containing 30% hydrogen peroxide was confirmed.

Study on Landslide using GIS and Remote Sensing at the Kangneung Area(II)-Landslide Susceptibility Mapping and Cross-Validation using the Probability Technique (GIS 및 원격탐사를 이용한 2002년 강릉지역 태풍 루사로 인한 산사태 연구(II)-확률기법을 이용한 강릉지역 산사태 취약성도 작성 및 교차 검증)

  • Lee Saro;Lee Moung-Jin;Won Joong-Sun
    • Economic and Environmental Geology
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    • v.37 no.5
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    • pp.521-532
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    • 2004
  • The aim of this study is to evaluate the susceptibility of landslides at Kangneung area, Korea, using a Geographic Information System (GIS) and remote sensing. Landslide locations were identified from interpretation of satellite image and field surveys. The topographic, soil, forest, geologic, lineament and land cover data were collected, processed and constructed into a spatial database using GIS and remote sensing data. Using frequency ratio model which is one of the probability model, the relationships between landslides and related factors such as slope, aspect, curvature and type of topography, texture, material, drainage and effective thickness of soil, type, age, diameter and density of wood, lithology, distance from lineament and land cover were calculated as frequency ratios. Then, the frequency ratio were summed to calculate a landslide susceptibility indexes and the landslide susceptibility maps were generated using the indexes. The results of the analysis were verified and cross-validated using actual landslide location data. The verification results showed satisfactory agreement between the susceptibility map and the existing data on landslide locations.

The Effect of Advanced Clinical Practicum on Clinical Competence for Nursing Student (종합선택실습이 간호대학생의 임상실무수행능력에 미치는 영향)

  • Kim, Jisoo;Kim, Young-Sook;Kim, Hye Soon;Jo, Hyun Sook;Lee, Eun-Ja;Lee, Yeo Jin;Kim, Yunmi;Park, Kwang-Hi
    • Proceedings of the Korea Contents Association Conference
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    • 2011.05a
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    • pp.381-382
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    • 2011
  • 본 연구는 4주간의 종합선택실습이 간호대학생의 임상수행 능력 변화에 미치는 영향을 파악하기 위한 것으로 4주간의 종합선택실습을 이수한 4학년 간호 대학생 128을 대상으로 하였고 임상실무수행능력 평가도구를 이용하여 실무능력변화를 측정하였다. 연구 결과 종합선택실습 전의 임상실무능력이 70.4점에서 실습 후에는 124.8점으로 증가(p<.001)되었고 직접간호활동과 간접간호활동의 모든 하위 영역에서 실습 후의 임상실무수행능력이 유의하게 증가되었다. 또한 상위 성적 30% 학생의 종합선택실습 후의 임상실무수행능력이 중간 40%의 학생에 비해 더 유의하게 증가한 것으로 나타났다(p=.047).

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A Study of Impeller's Design and CFD Analysis for Axial Flow Blood Pump (축류형 혈액펌프 개발을 위한 임펠러의 설계 및 해석에 대한 연구)

  • 임상필;김동욱
    • Proceedings of the KAIS Fall Conference
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    • 2002.11a
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    • pp.193-196
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    • 2002
  • 완전인공심장은 크게 정상류형과 박동류형이 있다. 정상류형 인공심장중 축류형 혈액펌프는 기구가 간단하고 비용적형이기 때문에 소형화가 가능한 장점이 있지만, 가동중 발생하는 난류로 인해 용혈현상이 따른다는 단점이 있다. 이 용혈의 형성과정은 실제와 가까운 모의실험을 하지 않고서는 알 수가 없다. 따라서 본 연구에서는 모의 실험단계를 거치지 않고 유한요소해석에 의한 난류평가를 통하여 용혈지수가 가장 낮은 임펠러의 형상을 연구하였다. 난류해석 결과, vane매수가 적을 경우 상대적으로 용혈지수가 낮게 나타나는 것을 알 수 있었으나 vane매수가 적을 경우에는 일정한 출구유량을 얻기 위해 임펠러의 고속회전 이 필요하며 이에 따른 난류에너지가 발생, 높은 용혈지수가 예상되므로 본 논문에서는 vane매수 4매-6매 중 6000-7000rpm의 회전속도사이의 조건으로 설계된 임펠러의 모델이 적당한 것으로 예측할 수 있었다.

The Prevalence of Low Back Pain Disability Index in College Students (대학생의 요통장애지수에 대한 분포)

  • Kwon, Won-An;Kim, Dong-Dae;Um, Ki-Mae;Song, Young-Hwa;Oh, Hyun-Ju;Lee, Jae-Hong
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.11 no.10
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    • pp.3846-3852
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    • 2010
  • Low back pain is commonly experienced by both adolescents and adults. The aim of this study is to research the prevalence of the Oswestry disability index(ODI) in their 20s of college students. The data was collected from the ODI questionnaire on functional disability measures for college students(males: 233, females: 407). Statistical analysis was carried out with SPSS 12.0 program, which was used for descriptive statistics and Pearson correlation analysis. The results were : Firstly, 'sitting' item was showed 'the highest score' and 'the lowest score' was 'personal care' in ODI items. Secondly, there was statistically significant between female(6.13) and male(4.62) on ODI but not ODI grade(p<0.01). Thirdly, there was a statistically significant relationship between ODI grade and each ODI items(p<0.01). These results have specific meaning as future clinical and epidemiological studies.

The Effect of Stress on the Happiness Index of Nursing College Students : Focusing on Mediating Effects of Optimism (스트레스가 간호대학생의 행복지수에 미치는 영향 : 낙관성의 매개효과를 중심으로)

  • Kim, Eun-Young;Lim, Kyoung-Suk
    • Journal of Digital Convergence
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    • v.15 no.12
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    • pp.381-391
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    • 2017
  • The purpose of this study is to investigate the effect of optimism on stress on happiness index. The subjects were 3 and 4 grade students who had clinical practice experience among 3 nursing students at G university, and 362 questionnaires were used as research data. The data analysis used regression analysis, SPSS macro and bootstrapping methods to examine the mediating effects of optimism on college students' stress and happiness. The results showed that stress, happiness, and optimism were significantly correlated, and stress had a direct effect on college students' happiness. In other words, the higher the level of stress, the lower the happiness index of college students. The optimism was partially mediated between stress and college students' happiness index. Therefore, in order to increase the happiness index of college students, it is necessary to develop and implement a program for happiness enhancement as one of the program strategies that can enhance stress.