• Journal of Life Science
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• v.23 no.8
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• pp.1064-1072
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• 2013

Circadian rhythm is controlled by hormonal oscillations governing the physiology of all living organisms. In mammals, the main function of the pineal gland is to transform the circadian rhythm generated in the hypothalamic suprachiasmatic nucleus into rhythmic signals of circulating melatonin characterized by a largely nocturnal increase that closely reflects the duration of night time. The pineal gland has lost direct photosensitivity, but responds to light via multi-synaptic pathways that include a subset of retinal ganglion cells. Rhythmic control is achieved through a tight coupling between environmental lighting and arylalkylamine-N-acetyltransferase (AANAT) expression, which is the rhythm-controlling enzyme in melatonin synthesis. Previous studies on the nocturnal expression of AANAT protein have described transcriptional, post-transcriptional, and post-translational regulatory mechanisms. Molecular mechanisms for dependent AANAT expression provide novel aspects for melatonin's circadian rhythmicity. Extensive animal research has linked pineal melatonin for the expression of seasonal rhythmicity in many mammalian species to the modulation of circadian rhythms and to sleep regulation. It has value in treating various circadian rhythm disorders, such as jet lag or shift-work sleep disorders. Melatonin, also, in a broad range of effects with a significant regulation influences many of the body's physiological functions. In addition, this hormone is known to influence reproductive, cardiovascular, and immunological regulation as well as psychiatric disorders.

• The Journal of the Acoustical Society of Korea
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• v.22 no.1
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• pp.69-77
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• 2003

Measurements of backscattered intensity were made over a shallow water using 300 ㎑and 1200 ㎑ bottom mounted ADCP (Acoustic Doppler Current Profiler) to determine the temporal variability of vertical distribution of high-frequency volume scattering strength (Sv). The variability of Sv in relatively deep water column(85 m and 113 m was due to the daily vertical migration, probably of larger zooplankton. However it was not found with 1200㎑ data at shallow water column. From the empirical orthogonal function (EOF) analysis using 1200㎑ data, the vertical distribution of the first mode eigenvectors of Sv is characterized by the presence of the maximum values near the bottom of the water.

• 한국지구과학회:학술대회논문집
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• 2010.04a
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• pp.42-47
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• 2010

본 연구에서는 2005~2007년 여름철(JJAS; 6~9월) 기간에 한반도 부근의 위성관측(TRMM) 및 지상관측(AWS) 강수량 그리고 대기오염 관측 자료를 이용하여 이들의 공간적 분포와 일주기 특성을 분석하였다. 이 기간에 AWS 평균 강수량은 전국적으로 약 5 mm/day 이었고, 제주도, 중부 내륙, 그리고 영 호남 경계 지역에서 9 mm/day 이상으로 많았다. PM10 (${\mu}g/m^3$) 미세먼지의 농도는 $27{\sim}57\;{\mu}g/m^3$ 이었고, 특히 수도권과 경남의 산업지역에서 $45\;{\mu}g/m^3$ 이상으로 높았다. 위성관측과 지상관측 강수량간의 상관(~0.8)은 매우 유의적이었다. AWS는 지점 관측이고 TRMM 관측은 면적평균임을 고려할 때, 위의 상관값은 상당히 높은 것으로 판단된다. 일주기 분석에서 미세먼지는 수도권 지역에서 오전에, 그리고 영남 지역에서는 오후 늦게 많이 발생하였다. AWS 강수량은 영동 및 경북 지역에서 이른 오전(2~8시)에, 이 지역 외에서는 오후 늦게(16~22시) 주로 발생하였다. 중부 지방의 강수 주기는 전선이 오후 3시부터 다음날 오전 4시까지 서해안에서 동해안으로 동진하는 형태를 잘 반영하였다.

• Sleep Medicine and Psychophysiology
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• v.20 no.2
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• pp.82-87
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• 2013

Objectives: Previous studies have reported an association between circadian preference and personality. Defense mechanism is unconscious ego process which deals with an individual's anxiety and is closely associated with one's personality. Our aim is to investigate the association between defense mechanism and circadian preference in medical students. Methods: One hundred forty eight medical students (70 males, 78 females), aged 22 to 30, answered the Beck Depression Inventory-II, Morningness-eveningness Questionnaire, and Korean version of Defense Style Questinnaire. Results: Consumption (beta=-0.262, p=0.001) and being a male (beta=0.175, p=0.031) were significant positive predictors of eveningness, while sublimation (beta=0.185, p=0.023) was a significant negative predictor of eveningness. Conclusion: Our study showed a relationship between specific defense mechanisms (i.e., consumption and sublimation) and eveningness in medical students, but it did not address whether the relationship is a causal one.

• Korean Journal of Ichthyology
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• v.22 no.4
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• pp.267-272
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• 2010

Laboratory-reared marbled flounder (Pleuronectes yokohamae) juveniles ($23.2{\pm}0.2mm$ total length; age 89 day) were sampled over a 48-h period to determine any diel patterns in RNA/DNA ratios. RNA/DNA ratios were highest during daytime periods (0800, 1100, 1400, 1700 h) and significantly reduced at night (2000, 2300, 0200, 0500 h). Findings from this study indicate a diel variation in biochemical condition and suggest that special care should be taken in designing sampling plans, including sampling time and data analysis to account for this source of variability.

• The Korean Journal of Zoology
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• v.5 no.1
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• pp.13-20
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• 1962

1. 1957년 8월 7일부터 18일까지 계룡산에서 고도차분포를 조사하기 위하여 고도별 4 지점에서 과물 (복숭아, 도마도) trap를 사용하여 오전 6시와 오후 6시에 동시에 초파리를 채집하였다. 그리고 sweeping 도 하여 총 33 종을 채집하였는데 다음종들은 높은 지점에서 발견되었다. Microdrosophila purpurata, Mycodrosophila basalis, Parascaptomyz disticha, Scaptomyza aplicalis , Drosophila histrioides, D.difasciata, D.histrio. 그리고 초파리의 성비가 고도에 따라 변동하였음을 관찰하였는데 특히. D. suzukii 는 저지에서 충이 현저히 많았던 것이 700미 고지에서는 거의 1 : 1의 성비를 보여주었다. 300 미높이의 (B) 지점에서 D.lacertosa 와D. Coracina 의 일주기활동은 반대적이었는데 D.lacertosa 는 습도가 높은 아침에 주로 활동하고, D.coracina는 이와 반대로 주로 오후에 활동하고 있음을 알았다. 2. 초파리 집단의 계절적 변동을 조사하기 위하여 1958년 4월부터 11월까지 매일 중순삼일씩 공주잠업시험소구내 상전에서 그리고 동년 5월 터 11월까지는 매일 초순삼일식 계룡산에서 각각 5개의 과물 trap를 설치하고 비교관찰하엿따. 매월 초파리종들의 계절적 변동은 3 표와 4 표에 기재된 바와같다. 특히 D.auraria는 두장소에서 우점종이었는데 공주잠업시험소구내 상전에서는 9월에 최고에 달했고, 계룡산에서는 8월에 최고에 달하는 unimodality를 표시하였다. 3 . 초파리의 일주기활동을 조사하기 위하여1959년 6월부터 10월까지 공주잠업시험소구내 상전에서 매월 2일간씩 2시간마다 채집을 하였다. 이 지방에서 우점종인 D.auraria 는 매월 일주기활동에 있어서 bimodality를 형성하였는데 9, 10월에는 두 peak는 서로 근접되었다. 그리고 6월 26일 2시간마다 sweeping 법으로 채집한 D.auraria의 일주기활동도 비교연구하였는데 거의 같은 현상을 나타냈다.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2006.05a
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• pp.129-132
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• 2006

Recently, Society increasingly need the hish-rise building because of urban population concentration. and The hish-rise building need new systematic work-planning method. but it didn't use the construction project's work plan and management. his paper investigated efficient work-planning method. and the work-planning method in using domestic High-rise building's structure work. A investigated result is TACT, DOC LOB etc. and domestic using method is 3day and 4day-Cycle among the Tact. This paper is to compare and analysis two method. a purpose of paper is to analyse application through the case of using the work-planning method. also To find efficient method.

• Proceedings of the Acoustical Society of Korea Conference
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• spring
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• pp.433-438
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• 2002

연안역의 천해 해저면에 설치된 ADCP(Acoustic Doppler Current Profiler, 300kHz, 1200kHz)를 이용, 천해에서 체적 산란강도(volume scattering strength) 수직분포의 시간적인 변동 특성을 알아보았다. 수심 85m와 113m에서 ADCP로 측정한 산란강도의 일주기 변동성은 동물플랑크톤(zooplankton)으로 추측되는 산란체의 일주기 수직 이동(daily vertical migration)의 원인으로 추정되었다. 그러나 수심 20m의 천해에서 관측된 산란강도의 시변동성은 경험적 직교 함수(Empirical Orthogonal Function, EOF) 분석 결과 해저면 부근의 변화가 천해 체적 산란의 변동성에 큰 영향을 주는 것으로 나타났다.

• Proceedings of the Korean Society of Fisheries Technology Conference
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• 1998.06a
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• pp.352.1-352
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• 1998

• Journal of Life Science
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• v.27 no.5
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• pp.501-508
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• 2017

Bone morphogenetic proteins (BMPs) are multifunctional cytokines that play important roles in a variety of cellular functions. Among BMP family members, BMP2 efficiently promotes osteoblast differentiation through Smad-mediated runt-related transcription factor 2 (Runx2) expression. Several recent studies suggest that BMPs are associated with clock genes, in particular Bmal1. Bmal1 protein heterodimerizes with Clock protein and then induces period 1 (Per1) expression. However, the role of Per1 on osteoblast differentiation remains unclear. In this study, we investigated whether Per1 is involved in osteoblast differentiation. MC3T3-E1 cells were treated with BMP2 for induction of osteoblastic differentiation. Osteogenic maker gene and Per1 mRNA expression were measured using real-time PCR. Interestingly, BMP2 treatment induced Per1 mRNA expression in MC3T3-E1 cells. To further investigate the function of Per1 on osteoblast differentiation, MC3T3-E1 cells were transiently transfected with pCMV-Per1. Per1 overexpression increased Runx2 mRNA and protein levels. Also, mRNA expression and promoter activity of osteocalcin were upregulated by Per1 overexpression. To investigate the effect of interaction between Per1 and osteogenic condition, MC3T3-E1 cells were cultured in osteogenic medium containing ascorbic acid and ${\beta}$-glycerophosphate. Osteogenic medium-induced ALP staining level and mineralization were synergistically increased by overexpression of Per1. Taken together, these results demonstrate that Per1 is a positive regulator of osteoblast differentiation.