• Title/Summary/Keyword: 인체위해성평가

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Health Risk Assessments using GIS Method for the Abandoned Asbestos Mines (GIS 기법을 이용한 폐석면 광산의 위해성 평가)

  • Choi, Jin-Beom;Son, Ill;Noh, Jin-Hwan
    • Journal of the Mineralogical Society of Korea
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    • v.24 no.1
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    • pp.43-53
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    • 2011
  • Health risk assessments for the abandoned asbestos mine were usually performed with activity-based sampling (ABS) method, which was not a effective tool for indexing health risk on an exact small area of mine. A newly proposed potential index of health risk (PIHR) was applied with proper spatial determination of geographical information system (GIS) to assess quantitatively health risks. A new trial was applied to a certain abandoned mine in Boryong as follows: A high grade area of PIHR was estimated 7.8% of the whole area of the mine (about 27.3 ha). Based on US EPA IRIS (integrated risk information system) model considering lifetime excess cancer risk (LECR), the health risk assessment indicated that the high grade area increased from 3.0 ha through 12.9 ha to 19.5 ha with an increase of asbestos contents in soil from 0.36% (1E-04 level) through 0.1% (3E-05 level) to 0.04% (1E-05 level). These results can be effectively applied to determine reclamation area of the abandoned asbestos mine.

A study on Compound Sensibility of Odors and Colors for Aromatic Fabric Design (방향성 소재 디자인을 위한 향과 색의 복합 감성 연구)

  • 우승정;조길수
    • Science of Emotion and Sensibility
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    • v.6 no.2
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    • pp.37-47
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    • 2003
  • The objectives of this study were to find the relationship between the olfactory sense such as perfume and sense of sight and how it affects the sensibility based on the fact that ,senses are compound feeling from detective parts of human body. First, to build the emotional rate stale we selected the 19 pairs of adjective from the previous studies that overlaps smell, color, and clothes and added one pairs of related clause. Then each pair was divided into 7 level of emotional stage. In the experiment by the selected 15 man and woman from the visual design major student of Hong-ick Univ each student was given floral, jasmin, lavender, papaya and asked them to pick one color from I.R.I Hue & Tone chart for each smell. Then, analyzed the emotional rating of selected color for given smell. The emotional structure of smell and color consists five parts; 'Esthetics', 'Romance', 'Character', 'Intensity', 'Nature', There were significant differences in frequencies of selected colors for each given smell and gender difference also affected the color selected. Average value of emotional rating scale of smell and color was ,similar to the results from previous studies on relationship between smell and emotion.

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이동통신 주파수 대역 전자파에 대한 생체 반응

  • 박웅양;서정선
    • The Proceeding of the Korean Institute of Electromagnetic Engineering and Science
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    • v.12 no.2
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    • pp.62-70
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    • 2001
  • 우리 나라 인구의 절반 정도에 해당하는 수의 이동통신 전화가 사용되고 있다. 이동 전화 사용자의 수는 앞으로 더욱 증가할 것이며, 또한 이를 이용한 각종 정보의 교환이 늘어남으로써 개인당 사용량도 늘어날 것으로 생각된다. 사용빈도의 증가와 더불어 이동전화에 의한 뇌종양, 유방암 및 기형 등 각종 인체 질환 발생 가능성에 대한 우려가 늘어나고 있다. 이러한 이동통신 주파수 대역 전자파는 크게 이미 잘 알려진 전자기장이나 자외선, 방사선 등과 인체에 대한 효과가 비슷할 것이라고 생각할 수 있다. 물론 이들은 주파수 대역이 전혀 다르며 이에 따라 서로 다른 물리적 성질을 가지고 있다. 단순히 보유하고 있는 에너지의 크기만으로 비교할 수 있는 것이 아닌 것이다. 그럼에도 불구하고 자외선이나 방사선처럼 전자파도 인체 질환을 유도할 것으로 생각하고 있다. 전자통신제품 사용의 증가에 따라 전자파에 대한 생체 영향에 대한 연구결과들이 발표되고 있다. 특히 이동통신 사용에 따라 암발생이 증가하고 기형이 발생할 수 있다는 역학 및 생물학 연구 결과들이 있었다. 하지만 이 보다 더 많은 수의 논문들이 전자파와 종양 발생이 관련 없다고 얘기하고 있다. 이에 대한 논란은 더 많은 연구와 토론이 필요할 것이다. 정확한 이동전화 주파수대역 전자파가 생체에서 어떻게 작용하는지 알기 위해서는 전자파 자체의 생물리학적 작용기전에 대한 이해가 필요하다. 전자파에 대한 인체 영향을 정확히 분석하기 위해서는 DNA나 단백질 같은 분자수준에서 세포나 실험동물에서 어떤 변화가 발생하는지 분석하는 것이 필요하다. 세포 수준의 연구는 전자파와 한 종류의 세포의 관계를 직접 분석할 수 있다. 세포내에서 DNA나 단백질의 변화는 바로 조직 및 장기내에서의 변화를 의미한다. 하지만 생체내에서는 하나의 세포가 외부 자극에 반응하는 것보다 면역계, 신경계 및 순환계 등 타 장기나 세포의 영향이 존재하는 상황이다. 따라서 세포 수준에서 전자파만의 효과를 장기나 개체내에서 분석하는 전자파에 의한 종양발생 관계를 더 정확히 알 수 있을 것이다. 전자파 중에서 이동전화 주파수 대역에 대한 생체 연구는 많지 않으나 이들로부터 이 주파수 대역의 전자파에 대한 생체 영향 평가 자료를 많이 모을 수 있다. 이러한 자료를 이용하면 핸드폰과 전자파에 대한 위해성 평가를 할 수 있다. 앞으로 다양한 수준에서 생체 영향을 분석함으로써 전자파 노출에 대한 효과를 알 수 있을 것이다.

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High-Risk Area for Human Infection with Avian Influenza Based on Novel Risk Assessment Matrix (위험 매트릭스(Risk Matrix)를 활용한 조류인플루엔자 인체감염증 위험지역 평가)

  • Sung-dae Park;Dae-sung Yoo
    • Korean Journal of Poultry Science
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    • v.50 no.1
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    • pp.41-50
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    • 2023
  • Over the last decade, avian influenza (AI) has been considered an emerging disease that would become the next pandemic, particularly in countries like South Korea, with continuous animal outbreaks. In this situation, risk assessment is highly needed to prevent and prepare for human infection with AI. Thus, we developed the risk assessment matrix for a high-risk area of human infection with AI in South Korea based on the notion that risk is the multiplication of hazards with vulnerability. This matrix consisted of highly pathogenic avian influenza (HPAI) in poultry farms and the number of poultry-associated production facilities assumed as hazards of avian influenza and vulnerability, respectively. The average number of HPAI in poultry farms at the 229-municipal level as the hazard axis of the matrix was predicted using a negative binomial regression with nationwide outbreaks data from 2003 to 2018. The two components of the matrix were classified into five groups using the K-means clustering algorithm and multiplied, consequently producing the area-specific risk level of human infection. As a result, Naju-si, Jeongeup-si, and Namwon-si were categorized as high-risk areas for human infection with AI. These findings would contribute to designing the policies for human infection to minimize socio-economic damages.

제 3세대 백금착체 항암제 신약개발: SKI 2053R의 제 1상 임상연구

  • 김노경;신상구;방영주;허대석;김기협;김대기;조용백
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1994.04a
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    • pp.187-187
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    • 1994
  • 선경인더스트리 연구소에서 개발된 100 여종의 새로운 백금착체 항암제 중 그 동안의 전임상연구를 통해 항암효과가 우수하고 안정성이 확인된 항암제인 SKI 2053R의 인체내 최대내약용량을 결정하고 부작용 및 항암효과를 평가하고 약제의 인체내 약동학적 특성을 검토하기 위해 각종 악성종양 환자들을 대상으로 제 1상 임상연구를 시행하였다. 약제의 투여는 500m1의 5% 포도당용액에 용해하여 1시간에 걸쳐 정주하였으며 병의 악화나 심한 독성이 없으면 치료를 매 4주마다 반복하였다. SKI 2053R의 초기용량은 생쥐에서의 LD$_{10}$의 1/10에 해당하는 40 mg/$m^2$로 하였고, 용량의 단계별 증가는 modified Fibonacci법에 따랐다. 각 단계별로 3명이상의 환자를 치료하여 WHO 기준상 3도 이상의 부작용이 2/6 이상에서 나타날 때의 용량을 최대내약용량으로 설정하였다.

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Potential Human Risk Assessment of PCBs and OCPs in Edible Fish Collected from the Offshore of Busan (부산 연근해의 해양오염퇴적물과 식용 어류 체내의 PCBs와 유기염소계 농약의 분포 및 잠재적인 인체 위해성평가)

  • Choi, Jin Young;Yang, Dong-Beom;Hong, Gi-Hoon;Kim, Suk Hyun;Chung, Chang Soo;Kim, Kyoung-Rean;Cho, Kyung Duk
    • Journal of Korean Society of Environmental Engineers
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    • v.34 no.12
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    • pp.810-820
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    • 2012
  • Polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs) contents in marine sediment and edible fish (4 species) from the estuary near the Yongho wharf in Busan were determined to assess their presence and their potential health risk to the local population through fish consumption was also assessed. Levels of ${\Sigma}PCBs$ and ${\Sigma}DDTs$ in marine sediment were 3.22~197.65 and 1.77~20.27 ng/g dw, respectively. HCHs and endosulfan sulfate concentrations in bottom sediment were 1.42~6.08, 0.56~13.89 ng/g dw, respectively. The bottom sediment in the offshore of the Yongho wharf may be characterized as semi-polluted status with potential adverse marine biological effects in terms of sediment quality guidelines of US NOAA. The mean concentrations of ${\Sigma}PCBs$ in the tissues of olive flounder (Paralichthys olivaceus), Korean rockfish (Sebastes schlegelii), file fish (Stephanolepis cirrhifer) and abbysal searobin (Lepidotrigla abyssalis) were 67.37, 10.20, 48.26, 22.81 ng/g lw, respectively. DDTs and HCHs were also detected in all fish samples. Lifetime cancer risk and target hazard quotient to local residents due to those fish consumption were found to pose negligible cancer and non-cancer risk.

A Study on Level of Service of Pedestrian Facility in Transfer Stations at Urban Railroad (도시철도 환승역의 환승보행시설의 서비스수준에 관한 연구)

  • Jang, Seong-Yong;Han, Sung-Yoeb;Kim, Si-Gon
    • Journal of the Korean Society for Railway
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    • v.13 no.3
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    • pp.339-348
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    • 2010
  • The government continues to make efforts to improve effectiveness, integration and connectivity of public transportation systems. But there have been only a few studies about it. This paper addresses the quality evaluation of pedestrian facility service in transfer stations at urban railroad. LOS (Level Of Service) model of urban railroad by facility based on the body ellipse and density recalculated considering the recent Korean body standard and the suggested Pedestrian Moving Equivalent (PME) and Pedestrian Waiting Equivalent (PWE). For LOS model for the ticket booths and ticket vending machines, queuing theory has been applied to determine LOS of Pedestrians. And the importance weights among the pedestrian facilities is obtained by applying AHP analysis. Lastly, this paper shows and discusses the evaluation results of overall LOS of pedestrian facilities of five urban railroad transfer stations in Seoul.

Safety Evaluation of Pesticide Residue in Five Fruits by Dietary Risk Index (소비자 위해지수를 이용한 5종 과일 중 잔류농약 안전성평가)

  • Lee, Je Bong;Hong, Su-Myeong;Kwon, Hye-Young;You, Are-Sun;Hong, Soon-Sung;Ihm, Yangbin
    • The Korean Journal of Pesticide Science
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    • v.18 no.4
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    • pp.336-341
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    • 2014
  • In order to determine the residual characteristics of pesticides in fruits and their effects on human health, monitoring of pesticide residues were conducted in apples, peaches, pears, grapes and citrus from the major cultivation areas in 2010. Safeties of the pesticides detected from the fruits were evaluated using the amounts of pesticide residue detected and dietary risk index (DRI). Samples were taken from 4-5 major fruit cultivation areas and then pesticide residues in the test fruits were analyzed with a liquid chromatographymass spectrometry (LC-MS/MS). Mean residue levels of the pesticides in fruits were 0.001-0.144 mg/kg. The DRIs were 0.55 for apple, 0.066 for peach, 0.008 for pear, 0.025 for grape, and 0.37 for citrus, respectively. The results indicated that the amounts of pesticide residues in domestic fruits might be safe, considering the regulatory concerning level 1.0.

Calculation of Induced Current in the Human Body around 765 kV Transmission Lines (765 kV 초고압 송전선 주변의 인체 유도전류 계산)

  • 명성호;이재복;허창수
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.9 no.6
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    • pp.802-812
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    • 1998
  • Safety related to electric field exposure for the personnel of high voltage power plant and substation is of importance. To analyze the induced current influencing on human body in this paper, we calculate directly capacitance in three dimension which is complex and time consuming, as not to separate the voltage source and the induced object using a effective modeling technique. The proposed algorithm in this paper has been applied to 765 kV high voltage transmission line to evaluate human hazard for the induced current through the case study. As the results, the short circuit current of human body has been identified in the range of 0.3 mA to 6.8 mA. Closing to transmission line, this range of short current can exceed 5 mA that ANSI recommended let-go current. Therefore, it is necessary to countermeasure such as putting on conductive clothing in live-line maintenance of transmission line.

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Design of Multi Sensor based on Context-aware System for Effective Video Information Acquisition (효율적인 영상정보 획득을 위한 멀티 센서 기반의 상황인지 시스템 설계)

  • Jeon, Min-Ho;Oh, Chang-Heon
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2012.05a
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    • pp.901-904
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    • 2012
  • In this paper, we proposed the context-aware system which can estimate the information on the objects and transmit video information by utilizing multi-sensors. The proposed system is to reduce the excessive video information from a system capturing videos outdoor. This system uses the human-detect sensor attached on the multi-sensor board and four ultrasonic sensor to measure the object's size and movement speed, to recognize the human body's information, and finally to send videos. In order to assess the performance of the context-aware system based on the multi sensor, a comparison has been made between video system and human-detect sensor. As a result, The body human-detect sensor had more reliable images and transmitted information more effectively than when the images were sent by server without sensors attached.

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