• Journal of Sensor Science and Technology
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• v.9 no.6
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• pp.404-415
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• 2000

This paper describes several performances and nondestructive inspection for deterioration due to forest fires in overhead transmission lines. After discussing corrosion mechanism such as atmospheric and galvanic corrosion for aged ACSR conductors and its detection for them are presented. Through impedance analysis of a solenoid coil, it is shown that the eddy current sensor may be available to inspect severe fault or local corrosion. As the solenoid coil changes its impedance when the test conductor is inserted into the coil, it can be possible to measure deterioration degree caused by forest fires. Tensile strength, extension rate and sensor impedance are tested for some samples degraded by artificial fire. As increasing blazed period to some extent, the strength of aluminum strand begins to be reduced remarkably, while galvanized steel strand holds the similar strength to the initial value, despite of appearing a little loss of zinc layer. In general, it is shown that the sensor impedance would be increased while the tension load of conductor is reduced and the extension rate is contrarily increased. Therefore, the sensor output could exhibit the changes of mechanical performances, and would be used to detect such deterioration caused by forest fire in ACSR conductors built on the ridge of mountains. Finally, it was verified that the solenoid coil could be applicable to obtain any crucial inform for serious deterioration due to forest fires.

• Journal of Conservation Science
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• v.29 no.1
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• pp.47-54
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• 2013

The following study tests for the effects of mordants on the production of restoration papers during the conservation process of damaged paper artifacts. For this, four different types of synthetic mordants that are being marketed currently ($K_2CO_3$, $AlK(SO_4)_2{\cdot}12H_2O$, $Cu_2SO_4{\cdot}5H_2O$, $FeSO_4$) were selected to produce samples for measuring variable properties through artificial degradation. The research conducts tests for changes in color, tensile index, and pH level (degree of acidity). The results for changes in color have shown that the value of ${\Delta}E^*ab$ of $K_2CO_3$ mordant sample was the highest, and the tests for tensile index have shown that the strength of dyeing sample was decreased in accordance with the aging time, but Changes according to the mordant was not evident. Finally, the findings for pH level have shown that samples with $Cu_2SO_4{\cdot}5H_2O$ and $FeSO_4$ have pH levels drop below 6. As a result, the research have concluded that mordants used for dyeing restoration paper were identified to have an affect in the dyeing and aging characteristics of the paper.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.44 no.1
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• pp.95-101
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• 2018

The epidermis which is stratified by epithelial tissue renewal based on keratinocyte differentiation protects the organism from various environmental insults by forming a physical barrier. Autophagy is a mechanism which mediates lysosomal delivery and degradation of protein aggregates, damaged organelles and intracellular microorganisms. Recent reports have shown that autophagy has critical roles for proper terminal differentiation to stratum corneum via removing metabolic organelles and nuclei. However, whether increasing autophagy can activate epidermal differentiation is unknown. Here, we screened a library of natural single compounds and discovered that betaine specifically increased the LC3 positive cytosolic punctate vesicles and LC3-I to LC3-II conversion in HaCaT human keratinocyte cell line, indicating increased autophagy flux. mTOR pathway, which negatively regulates autophagy, was not affected by betaine treatment, suggesting betaine-induced autophagy through an mTOR-independent pathway. Betaine-induced autophagy was also observed in primary human keratinocyte and skin equivalent. Furthermore, epidermal thickness was increased in skin equivalent under betaine treatment. Overall, our finding suggests that betaine as a novel regulator of autophagy may induce epidermal turnover and improve the skin barrier abnormality of the aged epidermis.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.34 no.2
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• pp.137-142
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• 2008

Echinacea purpurea, an indian traditional plant medicine has been widely used as herbal remedy for the treatment of disease such as colds or other infections. However, Echinacea purpurea extracts recently have been applied as a cosmetic ingredient for skin care. We artificially cultured Echinacea purpurea by using the bioreactor culture system for this study. We induced callus from Echinacea purpurea and separated adventitious roots, harvested and extracted after cultured in bioreactors. Previously, several studies have been reported on anti-oxidant and immuno-enhancing effects of Echinacea purpurea extract but other efficacies were not well known. In this study, we investigated the whitening, anti-wrinkle and anti-oxidant effects to know applicable value of tissue-cultured Echinacea purpurea adventitious roots extract(TCEPARE) as a cosmetic ingredient. TCEPARE did not show cytotoxicity until a concentration of 2% and showed the anti-oxidative effect in DPPH and NBT tests. Also, the extract decreased tyrosinase expression in a dose-dependent manner and inhibited melanin synthesis in B16 melanoma cells. TCEPARE reduced protein levels of MMP-1, 2 secreted in culture medium or in cell lysates. From these results we suggest that TCEPARE has potential benefits applicable as to cosmetic ingredient for skin care products.

• The Korean Journal of Mycology
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• v.34 no.1
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• pp.15-21
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• 2006

Extracts from 63 kinds of Pholiota sp. fruiting bodies were prepared using water and methanol, and then their physiological functionalities were investigated. The methanol extracts from Pholiota adiposa PAD030 showed high fibrinolytic activity and those of P. adiposa ASI PAD-022 showed potential inhibitory activity of 76.8% against ${\beta}-hydroxy-{\beta}-methylglutaryl(HMG)-CoA$ reductase. The highest antioxidant and tyrosinase inhibitory activities were found in the water extracts of Pholiota sp. PSP-015 (72.7%) and methanol extracts of P. nameko PNA-024 (69.5%), respectively. However, superoxide dismutase(SOD)-like activity and elastase inhibitory activity were low in almost of the extracts. The HMG-CoA reductase inhibitor from the fruiting body of P. adiposa PAD-022 which showed the highest functionality was extracted maximally when powder of the fruiting body was shaked at $30^{\circ}C$ for 12 h by methanol and its HMG-CoA reductase inhibitory activity was 80.2%.

• Korean Journal of Heritage: History & Science
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• v.46 no.3
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• pp.150-171
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• 2013

The most important part of conservation treatment of murals is to preserve them against the risk of a damage by injecting fixative into them when the painting loses its cohesion or powderization of pigments occurred due to occurrence of cracks inside the painting layer. However, studies on the stability of fixative used for painting layers of murals are still insufficient. This study manufactured a mural as a specimen and colored it with four kinds of pigments including oyster shell white, cinnabar, malachite and red clay and applied four kinds of fixative, including, Paraloid $B-72^{(R)}$, Caparol-$binder^{(R)}$, glue and Hydoxypropyl $cellulose^{(R)}$. artificially generated environmental changes in temperature, humidity and ultraviolet rays which may occur after the completion of conservation treatment. Then the changes in physical properties were observed in multifaceted ways such as color stability, contact angle, brilliance, adhesive strength and surface. As a result, this study found that ultraviolet rays and hot?humid environment have a large impact on color stability causing changes in brightness and chroma of all painting layers where the fixative were applied, except for oyster shell white and are considered the main factors of decomposition by accelerating the aging process of fixatives applied. In comparison to the synthetic resins that were also tested in this study, the traditional glue showed satisfactory results in terms of color stability and influence preservation and the hydrophile property. As it showed exceptionally outstanding adhesive strength in all painting layers in the aspect of adhesive strength, it is considered to be highly stabile for the fixation treatment of painting layers of mural.

• Korean Journal of Breeding Science
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• v.50 no.4
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• pp.529-533
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• 2018

Hyowon6, a mid-late maturing, good eating quality rice variety with multi-resistance, was developed by the rice breeding team of Pusan National University in 2013. This variety was derived from a cross between Hwayeong (as a multi-resistant parent) and Koshihikari (as a good eating quality parent). Selection by the pedigree breeding method was carried out until the $F_8$ generation. A promising line, JS14-12-36-8-5-3-1-1-1, was developed and designated as HY103 in 2013. This variety headed on August 22, which was 11 days later than that of Hwayeong. The culm length and panicle length of Hyowon6 was 85.7 cm and 21.1 cm, respectively. The number of panicles per hill was 14.5 and the number of grains per panicle was 101.7. The ratio of ripened grain was approximately 92% and the 1,000-grain weight was approximately 21.36 g for brown rice, which were similar to those of Hwayeong. Hyowon6 was moderately resistant to lodging and also to neck blast, leaf blight, and stripe virus. The glossiness value of Hyowon6 was 83, which was considerably higher than that of Hwayeong.

• Journal of Life Science
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• v.27 no.2
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• pp.247-266
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• 2017

Cordyceps is a traditional Chinese medicinal herb well-known in China, Korea and Japan since B.C. 2,000. The original entomopathogenic fungus, Cordyceps sinensis belonging to the genus Cordyceps could not be found inside Korean peninsula due to the absence of the host insect for the corresponding entomogenous fungus. The development of artificial production methods of Korean type Cordyceps using the silkworm Bombyx mori as in vivo culture medium for the the entomopathogenic fungus Paecilomyces tenuipes is the first, and wonderful occasion in the research history of insect industry of this global world. The aim of this article is to review the historical research background, mass-production methods, and pharmacological effects of the silkworm-dongchunghacho (Paecilomyces tenuipes) which is a newly developed Korean medicinal insect-borne mushroom, and another non-insect-borne medicinal mushroom (Cordyceps militaris and Cordyceps pruinosa). Their biological actions include anti-tumor, immunostimulating, anti-fatigue, anti-stress, anti-oxidant, anti-aging, anti-diabetic, anti-inflammatory, anti-thrombosis, hypolipidaemic and insecticidal effects. The bioactive principles are protein-bound polysaccharides (hexose, hexosamin), cordycepin, D-manitol, acidic polysaccharide etc. Protein-bound polysaccharides and n-butanol fractions were demonstrated to show a significant anti-tumor activities but did not show a cytotoxicities. D-mannitol exhibited a significant prolongation of the life span in tumor bearing mice. Ergosterol did not show an efficient anti-tumor activity, but showed a significant phagocytosis enhancing activity. Anti-tumor activity of silkworm-dongchunghacho might be attributed to immuno-stimulating activities rather than cytotoxic effects [164]. Also this review comprises the breeding of Dongchunghacho varieties, optimization of culture conditions, improvement of learning and memory by Dongchunghacho, application of them as foods and chemical constituents.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.45 no.2
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• pp.175-184
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• 2019

The epidermal growth factor (EGF) has a intrinsic function of inducing growth and proliferation of cells through interacting with cell membrane receptors in human epidermis and dermis layer. These functions of EGF are used as a main ingredient for wound healing medicines and anti-aging cosmetics. As a cosmetic ingredient, the EGF has a problem in exhibiting its natural efficacy due to the lack of the ability to penetrate through the stratum corneum, which is known as the skin barrier. In this study, a recombinant human epidermal growth factor ($MTD_{151}-EGF$) fused with the macromolecule transduction domain $(MTD)_{151}$ with the skin penetration ability was developed to improve the skin penetration efficiency of the EGF. Expression of $MTD_{151}-EGF$ was performed in E. coli transformed with a vector encoding the $MTD_{151}-EGF$ gene and then purified. The purified $MTD_{151}-EGF$ was evaluated using cell proliferation assay, cytotoxicity test and skin penetration test by franz diffusion cell assay and artificial skin. Cell proliferation activity of $MTD_{151}-EGF$ purified to high purity of 99% or above was equivalent to the EGF or better, and cytotoxicity was not observed. In addition, the $MTD_{151}-EGF$ showed an excellent penetration efficiency compared to the EGF in the skin penetration test with EGF and $MTD_{151}-EGF$ labeled by FITC in an artificial skin penetration model. Based on the quantitative analysis of the penetrating substance using franz diffusion cell assay, the amount of penetration was about 16 times more than that of EGF. These results can be regarded as an effective alternative to improve the existing physical transdermal penetration method related to the use of various active ingredients for cosmetics.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.35 no.3
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• pp.201-210
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• 1990

This study was carried out to determine the effect of mixture of hymexazole and metalaxyl(Tachigarace) on the growth and reducing low temperature injury in rice seedlings. The amount of mixture of hymexazole and metalaxyl (Tachigarace) applied to reduce low temperature injury was 0, 9, 18 and 36mgr per pot (5${\times}$15${\times}$10cm) by soil incorperation befor sowing. Aging seedling was investigated on the growth responses by the application of 0.36gr mixture of hymexazole and metalaxyl (Tachigarace) per tray (30${\times}$60${\times}$3cm) after cutting of leaf at 35 day-old seedling. Rice seedlings treated with mixture of hymexazole and metalaxyl (Tachigarace) were better in the growth of top and roots, dry weight, erecting and rooting abilities than untreated seedlings. The effective amount of mixture of hymexazole and metalaxyl (Tachigarace) to increase erecting and rooting abilities was 18 mgr per pot. Under low temperature treatment, 12$^{\circ}C$, the leaf discoloration and dead leaf percent of rice seedlings were markedly decreased in the seedlings treated with mixture of hymexazole and metalaxyl (Tachigarace) as compared with untreated seedlings. The more amount of mixture of hymexazole and metalaxyl (Tachigarace) upto 36mgr per pot, the more effective on the low temperature injury in the seedling. The effect of mixture of hymexazole and metalaxyl (Tachigarace) to reduce low temperature damage in rice seedlings was mainly due to decreasing less physiological activities on the expanding leaf area and rooting, transpiration, stomatal diffusion and chlorophyll content of the leaves and oxygen consumption of the roots. Plant height, top dry weight and leaf area of aging seedlings were increased with mixture of hymexazole and metalaxyl (Tachigarace) treatment and leaf cutting as compared with untreated seedling and intact leaf, respectively. The ratio of missing hill of aging seedling was increased with increasing the period of growing seedling and was decreased due to leaf cutting, whereas the effect of mixture of hymexazole and metalaxyl (Tachigarace) application was not observed. Rooting ability of aging seedlings was decreased with lengthening of the period of raised seedling and was increased with mixture of hymexazole and metalaxyl (Tachigarace) treatment and leaf cutting.