• Journal of the Institute of Electronics Engineers of Korea SP
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• v.42 no.5 s.305
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• pp.123-136
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• 2005

We propose a recognition system for superimposed patterns based on selective attention model and SVM which produces better performance than artificial neural network. The proposed selective attention model includes attention layer prior to SVM which affects SVM's input parameters. It also behaves as selective filter. The philosophy behind selective attention model is to find the stopping criteria to stop training and also defines the confidence measure of the selective attention's outcome. Support vector represents the other surrounding sample vectors. The support vector closest to the initial input vector in consideration is chosen. Minimal euclidean distance between the modified input vector based on selective attention and the chosen support vector defines the stopping criteria. It is difficult to define the confidence measure of selective attention if we apply common selective attention model, A new way of doffing the confidence measure can be set under the constraint that each modified input pixel does not cross over the boundary of original input pixel, thus the range of applicable information get increased. This method uses the following information; the Euclidean distance between an input pattern and modified pattern, the output of SVM, the support vector output of hidden neuron that is the closest to the initial input pattern. For the recognition experiment, 45 different combinations of USPS digit data are used. Better recognition performance is seen when selective attention is applied along with SVM than SVM only. Also, the proposed selective attention shows better performance than common selective attention.

• KSBB Journal
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• v.19 no.2
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• pp.113-117
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• 2004

The effect of ultrasonification on immuno-stimulatory activities of the extracts from Ephedra sinica Stapf and Rubus coreanus Miq. was observed by the growth of human immune cells. The extraction yields from water extracts and water extract with ultrasonification at 40$^{\circ}C$, 60$^{\circ}C$ and 100$^{\circ}C$ were compared. The highest yield was observed enhancement ratio 2.34% in the extract at 40$^{\circ}C$ with ultrasonification. The growth of human T-cell was increased up to 13.8${\times}$10$^4$ viable cells/$m\ell$ in adding 1.0 g/L of the ultrasonification extracts. The treated extracts increased the specific secretion of TNF-${\alpha}$ up to 10.5${\times}$10$\^$-4/ pg/cell. It was suggested that of the extracts on water the extraction yield with ultrasonification compared improved the extraction with ultrasonification of low than.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.34 no.2
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• pp.93-99
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• 2008

Until now, (-)-epigallocatechin-3-gallate(EGCG) is known as the most powerful antioxidant among green tea catechins having many beneficial effects on human skin. Considering that the content of catechins is variable according to many conditions such as solvent, temperature and pressure, we prepared the heat-epimerized-EGCG-mixture (HE-EGCG-mix) containing high content of gallocatechin-3-gallate(GCG) by epimerization during autoclaving process and found out its optimal condition for maximizing conversion from EGCG to GCG. To investigate the effects of EGCG and HE-EGCG-mix on skin barrier function, we performed in vivo experiments with hairless mice. We found that HE-EGCG-mix has more potent stimulating activity than EGCG for the production of involucrin 7(INV7) and for recovery of barrier function in SKH-1 mice. Also, we found that GCG stimulates $PPAR-{\alpha}$ transactivation more effectively than EGCG in vitro by transient transfection assay for $PPAR-{\alpha}$ activation activity. These imply that HE-EGCG-mix consisting of high content of GCG should stimulate more efficiently recovery of skin barrier through PPAR-mediated-kerationocyte differentiation than EGCG. In conclusion, our study may provide a possibility that GCG, the C-2 epimer of EGCG, could be a potentially effective agent for development of new cosmetics or health foods for recovery of skin barrier.

• The Korean Journal of Ecology
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• v.26 no.1
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• pp.23-28
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• 2003

In order to identify plant species and communities characteristic of lithospheric condition, forest vegetations of igneous(mainly granite) and sedimentary(mainly sandstone) areas in Kyungpook province were compared. We collected 108 phytosociological releves from the older forests over 20 years old. 444 vascular plant species and 25 plant communities were identified. Results of Principal Coordinates Analysis (PCA) indicated that lithospheric conditions and human impacts were the most important factors related to the plant community diversity and species richness. In the igneous rock areas net contribution degree (rNCD) of 139 species including Quercus serrata, Q. mongolica, Lindera obtusiloba and Fraxinus sieboldiana increased and those of Carpinus laxiflora and Styrax japonica decreased. In the sedimentary rock areas, to a lesser extent, 96 species including Q. aliena, Zanthoxylum schinifolium, Potentilla fragarioides var. major, Rhus javanica, and Plectranthus japonicus increased, whereas character species of Lindero-Quercion mongolicae such as Q. mongolica, Q. serrata, Rhododendron schlippenbachii, Acer mono and Styrax obassia decreased, and particularily the species Sasa borealis, the Alangium-Zelkova serrata community and the Philadelphus-Fraxinus mandshurica community were absent. The vegetation of sedimentary rock area is characterized as a regional type shaping dwarf pine forests and sparse and light broad-leaved forests.

• Journal of the Korean Society of Clothing and Textiles
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• v.32 no.6
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• pp.935-946
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• 2008

Religion is the symbolic form and action, linking the ultimate condition of life with human beings. Religious idea grasps the world through symbols and gives birth to the action through symbols. This research put its purpose in elucidating the effect of religion on the costume and its mechanism. It's focus is centered on Buddhism, Hinduism, and Islam which are among the world high religions. Part of this research also examines the mechanism in which several composing factors are expressed with rituals and manifested with costumes, this process was diagrammatized and suggested. The composing factors of religion such as belief system, experiences, community, and rituals are closely related. Ritual especially, is the symbolic action, practice, and the way of rescue, expressing religious meaning. Religious rituals such as imitative rituals, positive or negative rituals, sacrificial ritual, and rites of passage have been expressed with religious music or figurative art such as costume, construction, and art as well as religious ritual like ancestral rites. Religion has had a great effect on the overall culture including costume as a belief system by lightening the meaning of life and suggesting the solutions to the human problems such as anxiety or conflict.

• Microbiology and Biotechnology Letters
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• v.38 no.2
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• pp.183-189
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• 2010

In the course of screening for anti-acidosis and anti-diabetes agent from natural products, the inhibitory activities of Nepales plant extracts against microbial $\alpha$-amylase and $\alpha$-glucosidase were evaluated. Among the 100 different kinds of ethanol extracts, Cedrus deodara (Roxb.) G. Don and Myrica nagi Thunb showed strong inhibition activities against $\alpha$-amylase. The $IC_{50}$ values of C. deodara (Roxb.) G. Don, M. nagi Thunb and acarose, a commercial available anti-diabetes agent, were 44.5, 47.5 and $50.5\;{\mu}g/mL$, respectively. Considering the crude extract of C. deodara (Roxb.) G. Don, and M. nagi Thunb, these extracts have strong potentials as anti-acidosis or anti-diabates agent. In a while, Cleistocalyx operculatus (Roxb.) extract showed a good inhibition activity to $\alpha$-amylase and $\alpha$-glucosidase, even it was recently reported. The selected three extracts did not show any hemolysis activity against human red blood cell up to 1 mg/mL, and the inhibition activities were maintained by heat or acid treatment. Moreover, treatment of HCl (0.01N) for 1 h into C. operculatus (Roxb.) and M. nagi Thunb increased the inhibition activity from 50% to 70%. Our results suggest that C. deodara (Roxb.) G. Don, M. nagi Thunb, and C. operculatus (Roxb.) are potential as anti-acidosis and anti-diabetes agents.

• Archives of design research
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• v.12 no.2
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• pp.31-40
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• 1999

Because of the oocIear family due to the rapid industrialization and the growth of husband and wife bah working, the base of the tradition that the parents, all of the famly or the hamet oonmunity bring up the infants together in the important time to the infarts has been collapsed in Korea. Because working mothers camot bring up their children by themselves they got stressed and housewives do not have the oonfidence in rearing their infants and the fathers are isolated from home and the chikten instead of being exempted from the responsibility of rearing children. Therefore the common and comprehensive rearing system should be made for solving the child-rearing problem. For solving these problems and for the desirable infant-rearing and education, the joint irlart rearing, whidl compensates for the life, education and furthermore the sdlool edJcation through the volur1ary participation, has been prepared altematively. Compared to the traditional rearing system, joint infant-rearing is not only operated by the residents with the dues paid by the union members but also makes children experience the life force of natu"e in themselves. So the preparation of the standard of the suitable environment design for the joint infant-rearing is required which is diffrent from the traditional standard of the environmertal facilities for the traditional rearing system. The concept of joint infant-rearing was defind in this study through the reference and the ooncept of infant edJcation which is in operation suocessfully in Italy and Sweden in order to understand how the ooncept of infant education has changed as the ages have dlanged. And the basic principals for the formation of physical envirorvnert and the spare design and the envirorYnertal oondition for the practical environmental design was also studied through the reference. And after study about the concept. figure and physical environmental suggestion, the concept, standard and element of joint infant-rearing environment design was suggested. And as the final conclusion, the design requirement of the envirorvnertal design for the joint infant-rearing was suggested.

• Journal of Life Science
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• v.26 no.2
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• pp.265-274
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• 2016

Toxin-antitoxin (TA) systems are ubiquitous genetic modules that are evolutionally conserved in bacteria and archaea. TA systems composed of an intracellular toxin and its antidote (antitoxin) are currently classified into five types. Commonly, activation of toxins under stress conditions inhibits diverse cellular processes and consequently induces cell death or reversible growth inhibition. These effects of toxins play various physiological roles in such as regulation of gene expression, growth control (stress response), programmed cell arrest, persister cells, programmed cell death, phage protection, stabilization of mobile genetic elements or postsegregational killing of plasmid-free cells. Accordingly, bacterial TA systems are commonly considered as stress-responsive genetic modules. However, molecule screening for activation of toxin in TA system is available as development of antimicrobial agents. In addition, cytotoxic effect induced by toxin is used as effective cloning method with antitoxic effect of antitoxin; consequently cells containing cloning vector inserted a target gene can survive and false-positive transformants are removed. Also, TA system is applicable to efficient single protein production in biotechnology industry because toxins that are site-specific ribonuclease inhibit protein synthesis except for target protein. Furthermore, some TA systems that induce apoptosis in eukaryotic cells such as cancer cells or virus-infected cells would have a wide range of applications in eukaryotes, and it will lead to new ways of treating human disease. In this review, we summarize the current knowledge on bacterial TA systems and their applications.

• Applied Chemistry for Engineering
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• v.19 no.3
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• pp.326-331
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• 2008

The purpose of this work is to develope sodium-containing nonstoichiometric apatitic coatings on solid substrate. The apatitic coatings prepared at different concentrations of sodium salt indicated that the presence of sodium ions exerted significant effects on the physicochemical properties of the apatitic coating including surface morphology, chemical state, and Ca/P ratio. The variation of these properties was sustained up to 0.01 mM of sodium ion concentration. The ratio of calcium to phosphorus was varied from 2.18 to 2.03 which indicated the apatitic coating prepared in this study was calcium-rich nonstoichiometric apatite. The structure of all the samples appeared to be low crystalline. In the presence of sodium ion within the apaptitic coating, the adhesion of human osteoblast-like SaOS-2 cells was significantly promoted. On the other hand, the proliferation of the cells on the apatitic coatings was decreased with the increase of sodium ions. This reverse response of SaOS-2 cells indicates that the interaction between SaOS-2 and apatitic surface triggered considerable changes in intracellular mechanisms including cellular signal transductions.

• Journal of KIISE:Computing Practices and Letters
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• v.15 no.4
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• pp.284-288
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• 2009

With explosively growing PPI databases, the computational approach for a prediction and configuration of PPI network has been a big stream in the bioinformatics area. Recent researches gradually consider physicochemical properties of proteins and support high resolution results with integration of experimental results. With regard to current research trend, it is very close future to complete a PPI network configuration of each organism. However, direct applying the PPI network to real field is complicated problem because PPI network is only a set of co-expressive proteins or gene products, and its network link means simple physical binding rather than in-depth knowledge of biological process. In this paper, we suggest a protein functional flow model which is a directed network based on a protein functions' relation of signaling transduction pathway. The vertex of the suggested model is a molecular function annotated by gene ontology, and the relations among the vertex are considered as edges. Thus, it is easy to trace a specific function's transition, and it can be a constraint to extract a meaningful sub-path from whole PPI network. To evaluate the model, 11 functional flow models of Homo sapiens were built from KEGG, and Cronbach's alpha values were measured (alpha=0.67). Among 1023 functional flows, 765 functional flows showed 0.6 or higher alpha values.